Peptide vaccines and peptidomimetics of EGFR (HER-1) ligand binding domain inhibit cancer cell growth in vitro and in vivo von Foy, Kevin Chu, Wygle, Ruthie M, Miller, Megan J, Overholser, Jay P, Bekaii-Saab, Tanios, Kaumaya, Pravin T P

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HER-3 peptide vaccines/mimics: Combined therapy with IGF-1R, HER-2, and HER-1 peptides induces synergistic antitumor effects against breast and pancreatic cancer cells von Miller, Megan Jo, Foy, Kevin C, Overholser, Jay P, Nahta, Rita, Kaumaya, Pravin TP

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Epidermal growth factor receptor blockade by antibody IMC‐C225 inhibits growth of a human pancreatic carcinoma xenograft in nude mice von Overholser, Jay P., Prewett, Marie C., Hooper, Andrea T., Waksal, Harlan W., Hicklin, Daniel J.

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Selective inhibition of vascular endothelial growth factor (VEGF) receptor 2 (KDR/Flk-1) activity by a monoclonal anti-VEGF antibody blocks tumor growth in mice von BREKKEN, Rolf A, OVERHOLSER, Jay P, STASTNY, Victor A, WALTENBERGER, Johannes, MINNA, John D, THORPE, Philip E

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A newly discovered PD-L1 B-cell epitope peptide vaccine (PDL1-Vaxx) exhibits potent immune responses and effective anti-tumor immunity in multiple syngeneic mice models and (synerg... von Guo, Linlin, Overholser, Jay, Darby, Heather, Ede, Nicholas J., Kaumaya, Pravin T.P

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Preclinical Studies of a Novel Human PD-1 B-Cell Peptide Cancer Vaccine PD1-Vaxx From BALB/c Mice to Beagle Dogs and to Non-Human Primates (Cynomolgus Monkeys) von Guo, Linlin, Overholser, Jay, Good, Anthony J, Ede, Nicholas J, Kaumaya, Pravin T P

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Immunogenicity and antitumor efficacy of a novel human PD-1 B-cell vaccine (PD1-Vaxx) and combination immunotherapy with dual trastuzumab/pertuzumab-like HER-2 B-cell epitope vacci... von Kaumaya, Pravin T. P., Guo, Linlin, Overholser, Jay, Penichet, Manuel L., Bekaii-Saab, Tanios

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Phase I Immunotherapy Trial with Two Chimeric HER-2 B-Cell Peptide Vaccines Emulsified in Montanide ISA 720VG and Nor-MDP Adjuvant in Patients with Advanced Solid Tumors von Bekaii-Saab, Tanios, Wesolowski, Robert, Ahn, Daniel H, Wu, Christina, Mortazavi, Amir, Lustberg, Maryam, Ramaswamy, Bhuvaneswari, Fowler, Jeffrey, Wei, Lai, Overholser, Jay, Kaumaya, Pravin T P

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Magnetic Fluorescent Bead-Based Dual-Reporter Flow Analysis of PDL1-Vaxx Peptide Vaccine-Induced Antibody Blockade of the PD-1/PD-L1 Interaction von Overholser, Jay, Guo, Linlin, Kaumaya, Pravin T P

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Antivascular endothelial growth factor receptor (fetal liver kinase 1) monoclonal antibody inhibits tumor angiogenesis and growth of several mouse and human tumors von PREWETT, M, HUBER, J, BOHLEN, P, HICKLIN, D. J, YIWEN LI, SANTIAGO, A, O'CONNOR, W, KING, K, OVERHOLSER, J, HOOPER, A, PYTOWSKI, B, WITTE, L

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Anti-Tumor Effects of Peptide Therapeutic and Peptide Vaccine Antibody Co-targeting HER-1 and HER-2 in Esophageal Cancer (EC) and HER-1 and IGF-1R in Triple-Negative Breast Cancer... von Overholser, Jay, Ambegaokar, Kristen Henkins, Eze, Siobhan M, Sanabria-Figueroa, Eduardo, Nahta, Rita, Bekaii-Saab, Tanios, Kaumaya, Pravin T P

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Selective targeting of angiogenic tumor vasculature by vascular endothelial-cadherin antibody inhibits tumor growth without affecting vascular permeability von FANG LIAO, DOODY, Jacqueline F, OVERHOLSER, Jay, FINNERTY, Bridget, BASSI, Rajiv, YAN WU, DEJANA, Elisabetta, KUSSIE, Paul, BOHLEN, Peter, HICKLIN, Daniel J

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Monoclonal antibody to vascular endothelial-cadherin is a potent inhibitor of angiogenesis, tumor growth, and metastasis von FANG LIAO, YIWEN LI, HICKLIN, Daniel J, BOHLEN, Peter, O'CONNOR, William, ZANETTA, Lucia, BASSI, Rajiv, SANTIAGO, Angel, OVERHOLSER, Jay, HOOPER, Andrea, MIGNATTI, Paolo, DEJANA, Elisabetta

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IGF-1R peptide vaccines/mimics inhibit the growth of BxPC3 and JIMT-1 cancer cells and exhibit synergistic antitumor effects with HER-1 and HER-2 peptides von Foy, Kevin Chu, Miller, Megan J, Overholser, Jay, Donnelly, Siobhan M, Nahta, Rita, Kaumaya, Pravin TP

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Anti‐tumor and anti‐angiogenic effects in mice of heparin conjugated to angiostatic steroids von Derbyshire, Elaine J., Comin, Georgina A., Yang, Yong‐Ching, Overholser, Jay, Watkins, Linda, Thorpe, Philip E.

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