A non-canonical cGAS–STING–PERK pathway facilitates the translational program critical for senescence and organ fibrosis von Zhang, Dan, Liu, Yutong, Zhu, Yezhang, Zhang, Qian, Guan, Hongxing, Liu, Shengduo, Chen, Shasha, Mei, Chen, Chen, Chen, Liao, Zhiyong, Xi, Ying, Ouyang, Songying, Feng, Xin-Hua, Liang, Tingbo, Shen, Li, Xu, Pinglong

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Two HEPN domains dictate CRISPR RNA maturation and target cleavage in Cas13d von Zhang, Bo, Ye, Yangmiao, Ye, Weiwei, Perčulija, Vanja, Jiang, Han, Chen, Yiyang, Li, Yu, Chen, Jing, Lin, Jinying, Wang, Siqi, Chen, Qi, Han, Yu-San, Ouyang, Songying

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Mechanistic insights into the R-loop formation and cleavage in CRISPR-Cas12i1 von Zhang, Bo, Luo, Diyin, Li, Yu, Perčulija, Vanja, Chen, Jing, Lin, Jinying, Ye, Yangmiao, Ouyang, Songying

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Biochemical and structural characterization of the BioZ enzyme engaged in bacterial biotin synthesis pathway von Zhang, Sitao, Xu, Yongchang, Guan, Hongxin, Cui, Tao, Liao, Yuling, Wei, Wenhui, Li, Jun, Hassan, Bachar H., Zhang, Huimin, Jia, Xu, Ouyang, Songying, Feng, Youjun

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Regulation of phosphoribosyl ubiquitination by a calmodulin-dependent glutamylase von Gan, Ninghai, Zhen, Xiangkai, Liu, Yao, Xu, Xiaolong, He, Chunlin, Qiu, Jiazhang, Liu, Yancheng, Fujimoto, Grant M., Nakayasu, Ernesto S., Zhou, Biao, Zhao, Lan, Puvar, Kedar, Das, Chittaranjan, Ouyang, Songying, Luo, Zhao-Qing

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The emerging roles of the DDX41 protein in immunity and diseases von Jiang, Yan, Zhu, Yanping, Liu, Zhi-Jie, Ouyang, Songying

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NOD1 Promotes Antiviral Signaling by Binding Viral RNA and Regulating the Interaction of MDA5 and MAVS von Wu, Xiao Man, Zhang, Jie, Li, Peng Wei, Hu, Yi Wei, Cao, Lu, Ouyang, Songying, Bi, Yong Hong, Nie, Pin, Chang, Ming Xian

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The bacterial deubiquitinase Ceg23 regulates the association of Lys-63–linked polyubiquitin molecules on the Legionella phagosome von Ma, Kelong, Zhen, Xiangkai, Zhou, Biao, Gan, Ninghai, Cao, Yang, Fan, Chengpeng, Ouyang, Songying, Luo, Zhao-Qing, Qiu, Jiazhang

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Functional Features and Current Applications of the RNA‐Targeting Type VI CRISPR‐Cas Systems von Perčulija, Vanja, Lin, Jinying, Zhang, Bo, Ouyang, Songying

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Structural basis of antiphage immunity generated by a prokaryotic Argonaute-associated SPARSA system von Zhen, Xiangkai, Xu, Xiaolong, Ye, Le, Xie, Song, Huang, Zhijie, Yang, Sheng, Wang, Yanhui, Li, Jinyu, Long, Feng, Ouyang, Songying

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Structural and biochemical analyses of the tetrameric cell binding domain of Lys170 from enterococcal phage F170/08 von Xu, Xiaolong, Zhang, Dandan, Zhou, Biao, Zhen, Xiangkai, Ouyang, Songying

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The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response von Parvatiyar, Kislay, Zhang, Zhiqiang, Teles, Rosane M, Ouyang, Songying, Jiang, Yan, Iyer, Shankar S, Zaver, Shivam A, Schenk, Mirjam, Zeng, Shang, Zhong, Wenwan, Liu, Zhi-Jie, Modlin, Robert L, Liu, Yong-jun, Cheng, Genhong

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Structural Analysis of the STING Adaptor Protein Reveals a Hydrophobic Dimer Interface and Mode of Cyclic di-GMP Binding von Ouyang, Songying, Song, Xianqiang, Wang, Yaya, Ru, Heng, Shaw, Neil, Jiang, Yan, Niu, Fengfeng, Zhu, Yanping, Qiu, Weicheng, Parvatiyar, Kislay, Li, Yang, Zhang, Rongguang, Cheng, Genhong, Liu, Zhi-Jie

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Structural basis for the dual catalytic activity of the Legionella pneumophila ovarian tumor (OTU) domain deubiquitinase LotA von Luo, Jiwei, Ruan, Xinglin, Huang, Zhijie, Li, Zekai, Ye, Le, Wu, Yongyu, Zhen, Xiangkai, Ouyang, Songying

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Structural transitions upon guide RNA binding and their importance in Cas12g-mediated RNA cleavage von Liu, Mengxi, Li, Zekai, Chen, Jing, Lin, Jinying, Lu, Qiuhua, Ye, Yangmiao, Zhang, Hongmin, Zhang, Bo, Ouyang, Songying

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Interplay between bacterial deubiquitinase and ubiquitin E3 ligase regulates ubiquitin dynamics on Legionella phagosomes von Liu, Shuxin, Luo, Jiwei, Zhen, Xiangkai, Qiu, Jiazhang, Ouyang, Songying, Luo, Zhao-Qing

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Pyroptosis: Induction and inhibition strategies for immunotherapy of diseases von Wu, Junjun, Wang, Hong, Gao, Pu, Ouyang, Songying

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Structural analysis of asparaginyl endopeptidase reveals the activation mechanism and a reversible intermediate maturation stage von Zhao, Lixia, Hua, Tian, Crowley, Christopher, Ru, Heng, Ni, Xiangmin, Shaw, Neil, Jiao, Lianying, Ding, Wei, Qu, Lu, Hung, Li-Wei, Huang, Wei, Liu, Lei, Ye, Keqiang, Ouyang, Songying, Cheng, Genhong, Liu, Zhi-Jie

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NLRC3, a Member of the NLR Family of Proteins, Is a Negative Regulator of Innate Immune Signaling Induced by the DNA Sensor STING von Zhang, Lu, Mo, Jinyao, Swanson, Karen V., Wen, Haitao, Petrucelli, Alex, Gregory, Sean M., Zhang, Zhigang, Schneider, Monika, Jiang, Yan, Fitzgerald, Katherine A., Ouyang, Songying, Liu, Zhi-Jie, Damania, Blossom, Shu, Hong-Bing, Duncan, Joseph A., Ting, Jenny P.-Y.

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A secreted effector with a dual role as a toxin and as a transcriptional factor von Wang, Dandan, Zhu, Lingfang, Zhen, Xiangkai, Yang, Daoyan, Li, Changfu, Chen, Yating, Wang, Huannan, Qu, Yichen, Liu, Xiaozhen, Yin, Yanling, Gu, Huawei, Xu, Lei, Wan, Chuanxing, Wang, Yao, Ouyang, Songying, Shen, Xihui

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