Lck is a key target of imatinib and dasatinib in T-cell activation von Lee, K C, Ouwehand, I, Giannini, A L, Thomas, N S, Dibb, N J, Bijlmakers, M J

Volltext

In Vitro Susceptibility of Candida Species to Four Antifungal Agents Assessed by the Reference Broth Microdilution Method von Eksi, Fahriye, Balci, Iclal, Gayyurhan, Efgan Dogan

Volltext

Single-cell RNA-sequencing of differentiating iPS cells reveals dynamic genetic effects on gene expression von Cuomo, Anna S. E., Seaton, Daniel D., McCarthy, Davis J., Martinez, Iker, Bonder, Marc Jan, Garcia-Bernardo, Jose, Amatya, Shradha, Madrigal, Pedro, Isaacson, Abigail, Buettner, Florian, Knights, Andrew, Natarajan, Kedar Nath, Vallier, Ludovic, Marioni, John C., Chhatriwala, Mariya, Stegle, Oliver

Volltext

Optimization of Culture Conditions (Sucrose, pH, and Photoperiod) for In Vitro Regeneration and Early Detection of Somaclonal Variation in Ginger Lime (Citrus assamensis) von Mad Yussof, Anis Idayu, Mohamed, Normadiha, Taha, Rosna Mat, Mahmad, Noraini, Yaacob, Jamilah Syafawati, Saleh, Azani

Volltext

Rheumatoid arthritis association at 6q23 von Worthington, Jane, Thomson, Wendy, Barton, Anne, Ke, Xiayi, Eyre, Steve, Hinks, Anne, Bowes, John, Donn, Rachelle, Symmons, Deborah, Hider, Samantha, Bruce, Ian N, Wilson, Anthony G, Marinou, Ioanna, Morgan, Ann, Emery, Paul, Carter, Angela, Steer, Sophia, Hocking, Lynne, Reid, David M, Wordsworth, Paul, Harrison, Pille, Strachan, David

Volltext

Whole genome sequencing reveals that genetic conditions are frequent in intensively ill children von French, Courtney E., Delon, Isabelle, Dolling, Helen, Sanchis-Juan, Alba, Shamardina, Olga, Mégy, Karyn, Abbs, Stephen, Austin, Topun, Bowdin, Sarah, Branco, Ricardo G., Firth, Helen, Rowitch, David H., Raymond, F. Lucy

Volltext

Efficiency and safety of varying the frequency of whole blood donation (INTERVAL): a randomised trial of 45 000 donors von Di Angelantonio, Emanuele, Thompson, Simon G, Kaptoge, Stephen, Moore, Carmel, Ouwehand, Willem H, Roberts, David J, Danesh, John, Di Angelantonio, Emanuele, Thompson, Simon G, Kaptoge, Stephen, Moore, Carmel, Walker, Matthew, Armitage, Jane, Roberts, David J, Danesh, John, Donovan, Jenny, Henry, Rachel, Hunt, Beverley J, Miflin, Gail, Green, Jane, Watkins, Nicholas A, McDermott, Alan, Thomson, Claire, Tolkien, Zoe, Williamson, Lorna, Allen, David, Sambrook, Jennifer, Hammerton, Tracey, Choudry, Fizzah, Ghevaert, Cedric, Johnston, Kirstie, Kelly, Anne, Mo, Alfred, Page, Lizanne, Richardson, Penny, Senior, Peter, Wong, Henna, Murphy, Gavin, Newland, Adrian C, Greaves, Michael, Brain, Richard, Davies, Christine, Wakeman, Paula, Dent, Alison, Anthony, Ben, Bland, Desmond, Parrondo, Will, Vincent, Helen, Weatherill, Candy, Forsyth, Andrea, Butterfield, Carol, Wright, Tracey, Ellis, Karen, Poynton, Pat, Martin, Emma, Littler, Lara, Williams, Lindsay, Blair, Donna, Ackerley, Karen, Woods, Lynn, Stanley, Sophie, Walsh, Gemma, Franklin, Gayle, Sharpe, Sarah, Smith, Deborah, Botham, Lauren, Williams, Caroline, Alexander, Claire, Furnival, Diane, Patel, Shilpa, Roost, Carolyn, Sowerby, Sandra, Appleton, Mary Joy, Bays, Eileen, Bowyer, Geoff, Clarkson, Steven, Halson, Stuart, Holmes, Kate, Humphries, Gareth, Parvin-Cooper, Lee, Towler, Jason, Addy, Joanne, Barrass, Patricia, Dingwall, Hannah, Clarke, Victoria, Potton, Maria, Bolton, Thomas, Daynes, Michael, Spackman, Sarah, Momodu, Abudu, King, Adam, Oates, Nicholas, Ryan, Christine, Stubbins, Craig, Williams, Joanna, Brennan, James, Mochon, Cedric, Taylor, Samantha, Warren, Kimberley, Mant, Jonathan

Volltext

Transcriptional diversity during lineage commitment of human blood progenitors von Chen, Lu, Kostadima, Myrto, Martens, Joost H. A., Canu, Giovanni, Garcia, Sara P., Turro, Ernest, Downes, Kate, Macaulay, Iain C., Bielczyk-Maczynska, Ewa, Coe, Sophia, Farrow, Samantha, Poudel, Pawan, Burden, Frances, Jansen, Sjoert B. G., Astle, William J., Attwood, Antony, Bariana, Tadbir, de Bono, Bernard, Breschi, Alessandra, Chambers, John C., Consortium, BRIDGE, Choudry, Fizzah A., Clarke, Laura, Coupland, Paul, van der Ent, Martijn, Erber, Wendy N., Jansen, Joop H., Favier, Rémi, Fenech, Matthew E., Foad, Nicola, Freson, Kathleen, van Geet, Chris, Gomez, Keith, Guigo, Roderic, Hampshire, Daniel, Kelly, Anne M., Kerstens, Hindrik H. D., Kooner, Jaspal S., Laffan, Michael, Lentaigne, Claire, Labalette, Charlotte, Martin, Tiphaine, Meacham, Stuart, Mumford, Andrew, Nürnberg, Sylvia, Palumbo, Emilio, van der Reijden, Bert A., Richardson, David, Sammut, Stephen J., Slodkowicz, Greg, Tamuri, Asif U., Vasquez, Louella, Voss, Katrin, Watt, Stephen, Westbury, Sarah, Flicek, Paul, Loos, Remco, Goldman, Nick, Bertone, Paul, Read, Randy J., Richardson, Sylvia, Cvejic, Ana, Soranzo, Nicole, Ouwehand, Willem H., Stunnenberg, Hendrik G., Frontini, Mattia, Rendon, Augusto

Volltext

Loss-of-function nuclear factor κB subunit 1 (NFKB1) variants are the most common monogenic cause of common variable immunodeficiency in Europeans von Tuijnenburg, Paul, Jansen, Machiel H., Carss, Keren J., Baxendale, Helen, Chandra, Anita, Seneviratne, Suranjith L., Oksenhendler, Eric, Tool, Anton T.J., Whitehorn, Deborah, Turro, Ernest, Thaventhiran, James E., Kuijpers, Taco W., Adhya, Zoe, Anantharachagan, Ariharan, Arumugakani, Gururaj, Bacchelli, Chiara, Baxendale, Helen, Bibi, Shahnaz, Booth, Claire, Browning, Michael, Burns, Siobhan, Clifford, Hayley, Cooper, Nichola, Davies, Sophie, Devlin, Lisa, Edgar, David, Egner, William, Ghurye, Rohit, Gilmour, Kimberley, Goddard, Sarah, Gordins, Pavel, Hackett, Scott, Hague, Rosie, Hayman, Grant, Jolles, Stephen, Jones, Julie, Kelleher, Peter, Klein, Nigel, Kuijpers, Taco, Kumararatne, Dinakantha, Laffan, James, Lango Allen, Hana, Lear, Sara, Longhurst, Hilary, Maimaris, Jesmeen, McDermott, Elizabeth, Morrisson, Valerie, Nasir, Iman, Noorani, Sadia, Oksenhendler, Eric, Ponsford, Mark, Qasim, Waseem, Quinn, Ellen, Quinti, Isabella, Samarghitean, Crina, Savic, Sinisa, Seneviratne, Suranjith, Simeoni, Ilenia, Staples, Emily, Steele, Cathal, Thaventhiran, James, Thomas, Moira, Thrasher, Adrian, Worth, Austen, Yong, Patrick, Bradley, John, Hammerton, Tracey, Ouwehand, Willem, Raymond, F Lucy, Veltman, Marijke, Clements-Brod, Naomi, Davis, John, Dewhurst, Eleanor, Erwood, Marie, Frary, Amy, Linger, Rachel, Papadia, Sofia, Rehnstrom, Karola, Astle, William, Attwood, Antony, Bleda, Marta, Carss, Keren, Daugherty, Louise, Deevi, Sri, Graf, Stefan, Greene, Daniel, Halmagyi, Csaba, Matser, Vera, Meacham, Stuart, Megy, Karyn, Shamardina, Olga, Titterton, Catherine, Tuna, Salih, Turro, Ernest, von Ziegenweldt, Julie, Furnell, Abigail, Staines, Simon, Stephens, Jonathan, Whitehorn, Deborah, Watt, Christopher

Volltext

Characteristics of Streptococcus pneumoniae Strains Colonizing Upper Respiratory Tract of Healthy Preschool Children in Poland von Korona-Glowniak, Izabela, Malm, Anna

Volltext

Lactic Acid Bacteria: Microbiological and Functional Aspects von Vinderola, Gabriel, Ouwehand, Arthur, Salminen, Seppo, von Wright, Atte

Volltext

Enteropathogenic Escherichia coli Associated with Diarrhea in Children in Cairo, Egypt von Labeeb, Rania S., Ahmed, Entsar A., Abada, Emad A., Behiry, Iman K.

Volltext

Population-scale proteome variation in human induced pluripotent stem cells von Mirauta, Bogdan Andrei, Seaton, Daniel D., Bensaddek, Dalila, Brenes, Alejandro, Bonder, Marc Jan, Kilpinen, Helena, Stegle, Oliver, Lamond, Angus

Volltext

Phenotypic Characterization of EIF2AK4 Mutation Carriers in a Large Cohort of Patients Diagnosed Clinically With Pulmonary Arterial Hypertension von Hadinnapola, Charaka, Bleda, Marta, Haimel, Matthias, Screaton, Nicholas, Swift, Andrew, Dorfmüller, Peter, Preston, Stephen D, Southwood, Mark, Hernandez-Sanchez, Jules, Martin, Jennifer, Treacy, Carmen, Yates, Katherine, Bogaard, Harm, Church, Colin, Coghlan, Gerry, Condliffe, Robin, Corris, Paul A, Gibbs, Simon, Girerd, Barbara, Holden, Simon, Humbert, Marc, Kiely, David G, Lawrie, Allan, Machado, Rajiv, MacKenzie Ross, Robert, Moledina, Shahin, Montani, David, Newnham, Michael, Peacock, Andrew, Pepke-Zaba, Joanna, Rayner-Matthews, Paula, Shamardina, Olga, Soubrier, Florent, Southgate, Laura, Suntharalingam, Jay, Toshner, Mark, Trembath, Richard, Vonk Noordegraaf, Anton, Wilkins, Martin R, Wort, Stephen J, Wharton, John, Gräf, Stefan, Morrell, Nicholas W

Volltext

Genome-wide association study identifies eight loci associated with blood pressure von Jackson, Anne U, Burton, Paul R, Di Gregorio, Alessandra, Mohlke, Karen L, Galan, Pilar, Syvänen, Ann-Christine, Marrugat, Jaume, Jarvelin, Marjo-Riitta, Newton-Cheh, Christopher, Meitinger, Thomas, Watkins, Hugh, Lucas, Gavin, Soranzo, Nicole, Tobin, Martin D, Wain, Louise V, Kooner, Jaspal S, Wallace, Chris, Altshuler, David, Najjar, Samer S, Zeggini, Eleftheria, Felix, Stephan B, Freimer, Nelson B, Laakso, Markku, Homuth, Georg, Ferrucci, Luigi, Brown, Morris, Snieder, Harold, Wichmann, H Erich, Orho-Melander, Marju, Chambers, John C, Valle, Timo T, van der Schouw, Yvonne T, Ernst, Florian, Strachan, David P, van der Harst, Pim, Kathiresan, Sekar, Romanazzi, Valeria, Dörr, Marcus, McArdle, Wendy L, Peden, John F, Beckmann, Jacques S, Song, Kijoung, Yuan, Xin, Melander, Olle, Coin, Lachlan, Lim, Noha, Barroso, Inês, Eyheramendy, Susana, O'Reilly, Paul F, Salomaa, Veikko, Gut, Ivo G, Tuomilehto, Jaakko, Peltonen, Leena, Morken, Mario A, Org, Elin, Luan, Jian'an, Panico, Salvatore, de Jong, Paul E, Schwartz, Stephen M, Matullo, Giuseppe, Wareham, Nicholas J, Seedorf, Udo, Laan, Maris, Uiterwaal, Cuno S, Boehnke, Michael, Farrall, Martin, Elosua, Roberto, Webster, John, Vollenweider, Peter, Reffelmann, Thorsten, Abecasis, Gonçalo R, Rettig, Rainer, Zhao, Jing Hua, Khaw, Kay-Tee, Elliott, Katherine S, Forouhi, Nita G, Voight, Benjamin F, Caulfield, Mark, Dominiczak, Anna, Munroe, Patricia B, Zhai, Guangju, Loos, Ruth JF, Sacerdote, Carlotta, Mooser, Vincent, Bergmann, Sven, Lakatta, Edward G, Bingham, Sheila A, Numans, Mattijs E, Völker, Uwe, Stringham, Heather M, Jousilahti, Pekka, Williams, Frances M, Clarke, Robert, Allione, Alessandra, Spector, Tim D, Elliott, Paul, Collins, Francis S, Lorbeer, Roberto, Sanna, Serena, Ricceri, Fulvio

Volltext

Genetic determinants of ulcerative colitis include the ECM1 locus and five loci implicated in Crohn's disease von Ouwehand, Willem, Keniry, Andrew, Fisher, Sheila A, Jewell, Derek P, Anderson, Carl A, Prescott, Natalie J, Deloukas, Panos, Blaszczyk, Katarzyna, Mansfield, John C, Mathew, Christopher G, Watkins, Nick, Drummond, Hazel, Cummings, Fraser R, Forbes, Alastair, Barrett, Jeffrey C, Ravindrarajah, Radhi, Sanderson, Jeremy, Inouye, Mike, Hunt, Sarah, Nimmo, Elaine R, Johnson, Christopher, Bumpstead, Suzannah, Hanson, Catherine E, Lobo, Alan, Massey, Dunecan, Cardon, Lon, Ewels, Philip, Satsangi, Jack, Tremelling, Mark, Gwilliam, Rhian, Carter, Martyn, Berzuini, Carlo, Lees, Charlie W, Onnie, Clive M, Parkes, Miles, Lewis, Cathryn M

Volltext

Repeated Replication and a Prospective Meta-Analysis of the Association Between Chromosome 9p21.3 and Coronary Artery Disease von SCHUNKERT, Heribert, GÖTZ, Anika, BLANKENBERG, Stefan, TIRET, Laurence, DUCIMETIERE, Pierre, KENIRY, Andrew, GHORI, Mohammed J. R, SCHREIBER, Stefan, EL MOKHTARI, Nour Eddine, HALL, Alistair S, DIXON, Richard J, GOODALL, Alison H, BRAUND, Peter, LIPTAU, Henrike, POLLARD, Helen, SCHWARZ, Daniel F, HOTHOM, Ludwig A, WICHMANN, H.-Erich, KÖNIG, Inke R, FISCHER, Marcus, MEISINGER, Christa, OUWEHAND, Willem, DELOUKAS, Panos, MCGINNIS, Ralph, THOMPSON, John R, ERDMANN, Jeanette, ZIEGLER, Andreas, SAMANI, Nilesh J, TREGOUET, David-Alexandre, MANGINO, Massimo, LINSEL-NITSCHKE, Patrick, CAMBIEN, Francois, HENGSTENBERG, Christian, STARK, Klaus

Volltext

Identification of ADAMTS7 as a novel locus for coronary atherosclerosis and association of ABO with myocardial infarction in the presence of coronary atherosclerosis: two genome-wi... von Reilly, Muredach P, Dr, Li, Mingyao, PhD, He, Jing, PhD, Ferguson, Jane F, PhD, Stylianou, Ioannis M, PhD, Mehta, Nehal N, MD, Burnett, Mary Susan, PhD, Devaney, Joseph M, PhD, Knouff, Christopher W, MD, Thompson, John R, Prof, Horne, Benjamin D, PhD, Stewart, Alexandre FR, PhD, Assimes, Themistocles L, MD, Wild, Philipp S, MD, Allayee, Hooman, PhD, Nitschke, Patrick Linsel, MD, Patel, Riyaz S, MD, Martinelli, Nicola, MD, Girelli, Domenico, Prof, Quyyumi, Arshed A, Prof, Anderson, Jeffrey L, Prof, Erdmann, Jeanette, Prof, Hall, Alistair S, MD, Schunkert, Heribert, Prof, Quertermous, Thomas, Prof, Blankenberg, Stefan, Prof, Hazen, Stanley L, Prof, Roberts, Robert, Prof, Kathiresan, Sekar, MD, Samani, Nilesh J, Prof, Epstein, Stephen E, Prof, Rader, Daniel J, Prof

Volltext

Genome-wide association study of 14,000 cases of seven common diseases and 3,000 shared controls von Clayton, David G, Cardon, Lon R, Duncanson, Audrey, Ouwehand, Willem H, Todd, John A, Donnelly, Peter, Easton, Doug, Evans, David, Morris, Andrew P, Spencer, Chris C. A, Boorman, James P, Cant, Barbara, Everson, Ursula, Hussey, Judith M, Knight, Alexandra S, Nutland, Sarah, Stevens, Helen E, Watkins, Nicholas A, Jones, Richard W, Ring, Susan M, Breen, Gerome, Caesar, Sian, Green, Elaine K, Grozeva, Detelina, Jones, Ian R, Kirov, George, Moskvina, Valentina, Nikolov, Ivan, Collier, David A, Farmer, Anne, Williamson, Richard, Young, Allan H, Ball, Stephen G, Balmforth, Anthony J, Bishop, D. Timothy, Iles, Mark M, Dixon, Richard J, Stevens, Suzanne, Thompson, John R, Bredin, Francesca, Tremelling, Mark, Drummond, Hazel, Nimmo, Elaine R, Fisher, Sheila A, Forbes, Alastair, Lewis, Cathryn M, Prescott, Natalie J, Barbour, Jamie, Mohiuddin, M. Khalid, Mansfield, John C, Cummings, Fraser R, Connell, John, Dobson, Richard, Gungadoo, Johannie, Newhouse, Stephen J, Barton, Anne, Bruce, Ian N, John, Sally L, Potter, Catherine, Silman, Alan J, Symmons, Deborah P. M, Dunger, David B, Widmer, Barry, Frayling, Timothy M, Lango, Hana, Perry, John R. B, Groves, Christopher J, Rayner, Nigel W, Timpson, Nicholas J, Zeggini, Eleftheria, Newport, Melanie, Vannberg, Fredrik, Farrar, Claire, Wordsworth, Paul, Brown, Matthew A, Franklyn, Jayne A, Heward, Joanne M, Simmonds, Matthew J, Seal, Sheila, Stratton, Michael R, Ban, Maria, Conway, David, Chaney, Amy, Ghori, Mohammed J. R, Gwilliam, Rhian, Hunt, Sarah E, McGinnis, Ralph, Potter, Simon, Whittaker, Pamela, Widden, Claire, Withers, David, Hallgrimsdottir, Ingileif B, Vukcevic, Damjan, Bentley, David, Caulfield, Mark, Compston, Alistair, Farrall, Martin, Hall, Alistair S, Hattersley, Andrew T, Mathew, Christopher G

Volltext

Genome-wide analysis of differential transcriptional and epigenetic variability across human immune cell types von Ecker, Simone, Chen, Lu, Pancaldi, Vera, Bagger, Frederik O, Fernández, José María, Carrillo de Santa Pau, Enrique, Juan, David, Mann, Alice L, Watt, Stephen, Casale, Francesco Paolo, Sidiropoulos, Nikos, Rapin, Nicolas, Merkel, Angelika, Stunnenberg, Hendrik G, Stegle, Oliver, Frontini, Mattia, Downes, Kate, Pastinen, Tomi, Kuijpers, Taco W, Rico, Daniel, Valencia, Alfonso, Beck, Stephan, Soranzo, Nicole, Paul, Dirk S

Volltext