Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases von De Piano, Mario, Manuelli, Valeria, Zadra, Giorgia, Otte, Jonathan, Edqvist, Per-Henrik D., Pontén, Fredrik, Nowinski, Salpie, Niaouris, Athanasios, Grigoriadis, Anita, Loda, Massimo, Van Hemelrijck, Mieke, Wells, Claire M.

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Lipogenic signalling modulates prostate cancer cell adhesion and migration via modification of Rho GTPases von De Piano, Mario, Manuelli, Valeria, Zadra, Giorgia, Otte, Jonathan, Edqvist, Per-Henrik D, Ponten, Fredrik, Nowinski, Salpie, Niaouris, Athanasios, Grigoriadis, Anita, Loda, Massimo, Van Hemelrijck, Mieke, Wells, Claire M

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Visualizing Hypothalamic Network Dynamics for Appetitive and Consummatory Behaviors von Jennings, Joshua H., Ung, Randall L., Resendez, Shanna L., Stamatakis, Alice M., Taylor, Johnathon G., Huang, Jonathan, Veleta, Katie, Kantak, Pranish A., Aita, Megumi, Shilling-Scrivo, Kelson, Ramakrishnan, Charu, Deisseroth, Karl, Otte, Stephani, Stuber, Garret D.

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Calcium imaging in freely-moving mice during electrical stimulation of deep brain structures von Trevathan, James K, Asp, Anders J, Nicolai, Evan N, Trevathan, Jonathan, Kremer, Nicholas A, Kozai, Takashi D Yoshida, Cheng, David, Schachter, Mike, Nassi, Jonathan J, Otte, Stephani L, Parker, Jones G, Lujan, J Luis, Ludwig, Kip

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Gamma-ray burst science in the era of the Cherenkov Telescope Array von Inoue, Susumu, Granot, Jonathan, O’Brien, Paul T., Asano, Katsuaki, Bouvier, Aurelien, Carosi, Alessandro, Connaughton, Valerie, Garczarczyk, Markus, Gilmore, Rudy, Hinton, Jim, Inoue, Yoshiyuki, Ioka, Kunihito, Kakuwa, Jun, Markoff, Sera, Murase, Kohta, Osborne, Julian P., Otte, A. Nepomuk, Starling, Rhaana, Tajima, Hiroyasu, Teshima, Masahiro, Toma, Kenji, Wagner, Stefan, Wijers, Ralph A.M.J., Williams, David A., Yamamoto, Tokonatsu, Yamazaki, Ryo

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Single-Molecule Imaging of Platinum Ligand Exchange Reaction Reveals Reactivity Distribution von Esfandiari, N. Melody, Wang, Yong, Bass, Jonathan Y, Cornell, Trevor P, Otte, Douglas A. L, Cheng, Ming H, Hemminger, John C, McIntire, Theresa M, Mandelshtam, Vladimir A, Blum, Suzanne A

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An orally available non-nucleotide STING agonist with antitumor activity von Pan, Bo-Sheng, Perera, Samanthi A, Piesvaux, Jennifer A, Presland, Jeremy P, Schroeder, Gottfried K, Cumming, Jared N, Trotter, B Wesley, Altman, Michael D, Buevich, Alexei V, Cash, Brandon, Cemerski, Saso, Chang, Wonsuk, Chen, Yiping, Dandliker, Peter J, Feng, Guo, Haidle, Andrew, Henderson, Timothy, Jewell, James, Kariv, Ilona, Knemeyer, Ian, Kopinja, Johnny, Lacey, Brian M, Laskey, Jason, Lesburg, Charles A, Liang, Rui, Long, Brian J, Lu, Min, Ma, Yanhong, Minnihan, Ellen C, O'Donnell, Greg, Otte, Ryan, Price, Laura, Rakhilina, Larissa, Sauvagnat, Berengere, Sharma, Sharad, Tyagarajan, Sriram, Woo, Hyun, Wyss, Daniel F, Xu, Serena, Bennett, David Jonathan, Addona, George H

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Discovery of Potent and Orally Available Bicyclo[1.1.1]pentane-Derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors von Pu, Qinglin, Zhang, Hongjun, Guo, Liangqin, Cheng, Mangeng, Doty, Amy C, Ferguson, Heidi, Fradera, Xavier, Lesburg, Charles A, McGowan, Meredeth A, Miller, J. Richard, Geda, Prasanthi, Song, Xuelei, Otte, Karin, Sciammetta, Nunzio, Solban, Nicolas, Yu, Wensheng, Sloman, David L, Zhou, Hua, Lammens, Alfred, Neumann, Lars, Bennett, David Jonathan, Pasternak, Alexander, Han, Yongxin

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Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRASG12C Inhibitor von Ma, Xiaoshen, Sloman, David L., Duggal, Ruchia, Anderson, Kenneth D., Ballard, Jeanine E., Bharathan, Indu, Brynczka, Christopher, Gathiaka, Symon, Henderson, Timothy J., Lyons, Thomas W., Miller, Richard, Munsell, Erik V., Orth, Peter, Otte, Ryan D., Palani, Anandan, Rankic, Danica A., Robinson, Michelle R., Sather, Aaron C., Solban, Nicolas, Song, Xuelei Sherry, Wen, Xin, Xu, Zangwei, Yang, Yi, Yang, Ruojing, Day, Phil J., Stoeck, Alexander, Bennett, David Jonathan, Han, Yongxin

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Structure-Guided Discovery of Aminoquinazolines as Brain-Penetrant and Selective LRRK2 Inhibitors von Keylor, Mitchell H, Gulati, Anmol, Kattar, Solomon D, Johnson, Rebecca E, Chau, Ryan W, Margrey, Kaila A, Ardolino, Michael J, Zarate, Cayetana, Poremba, Kelsey E, Simov, Vladimir, Morriello, Gregori J, Acton, John J, Pio, Barbara, Yan, Xin, Palte, Rachel L, McMinn, Spencer E, Nogle, Lisa, Lesburg, Charles A, Adpressa, Donovon, Lin, Shishi, Neelamkavil, Santhosh, Liu, Ping, Su, Jing, Hegde, Laxminarayan G, Woodhouse, Janice D, Faltus, Robert, Xiong, Tina, Ciaccio, Paul J, Piesvaux, Jennifer, Otte, Karin M, Wood, Harold B, Kennedy, Matthew E, Bennett, David Jonathan, DiMauro, Erin F, Fell, Matthew J, Fuller, Peter H

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Effects of toroidal plasma current on divertor power depositions on Wendelstein 7-X von Gao, Yu, Geiger, Joachim, Jakubowski, Marcin W., Drewelow, Peter, Endler, Michael, Rahbarnia, Kian, Bozhenkov, Sergey, Otte, Matthias, Suzuki, Yasuhiro, Feng, Yuhe, Niemann, Holger, Pisano, Fabio, Ali, Adnan, Puig Sitjes, Aleix, Zanini, Marco, Laqua, Heinrich, Stange, Torsten, Marsen, Stefan, Szepesi, Tamas, Zhang, Daihong, Killer, Carsten, Hammond, Kenneth, Lazerson, Samuel, Cannas, Barbara, Thomsen, Henning, Andreeva, Tamara, Neuner, Ulrich, Schilling, Jonathan, Knieps, Alexander, Rack, Michael, Liang, Yunfeng

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Discovery of MK-1084: An Orally Bioavailable and Low-Dose KRAS G12C Inhibitor von Ma, Xiaoshen, Sloman, David L, Duggal, Ruchia, Anderson, Kenneth D, Ballard, Jeanine E, Bharathan, Indu, Brynczka, Christopher, Gathiaka, Symon, Henderson, Timothy J, Lyons, Thomas W, Miller, Richard, Munsell, Erik V, Orth, Peter, Otte, Ryan D, Palani, Anandan, Rankic, Danica A, Robinson, Michelle R, Sather, Aaron C, Solban, Nicolas, Song, Xuelei Sherry, Wen, Xin, Xu, Zangwei, Yang, Yi, Yang, Ruojing, Day, Phil J, Stoeck, Alexander, Bennett, David Jonathan, Han, Yongxin

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Influences of Steric Factors on the Reactivity and Structure of Diorganoalkoxysilylamides von Zibula, Lukas, Achternbosch, Moritz, Wattenberg, Jonathan, Otte, Felix, Strohmann, Carsten

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Development of a Green and Sustainable Manufacturing Process for a Key Intermediate to Nemtabrutinib (MK-1026): Sequential Deprotonation–Lithiation as a Batch–Flow Process von Otte, Douglas A. L., Larson, Reed T., Alwedi, Embarek, Armiger, Travis, Chen, Yonggang, Chung, Cheol K., Corry, James, Desmond, Richard, Fier, Patrick S., Franklin, Robert D., Guetschow, Erik D., Hall, Jackson R., Halsey, Holst M., Hartmanshenn, Clara, Jellett, Lisa, Kuhl, Nadine, Lévesque, François, McMullen, Jonathan P., Patel, Pratiq A., Paulines, Mellie June, Ren, Hong, Rodrigues, Vailankanni L., Ruccolo, Serge, Tan, Lushi, Thaisrivongs, David A., Xiao, Kai-Jiong

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Discovery of MK-1468: A Potent, Kinome-Selective, Brain-Penetrant Amidoisoquinoline LRRK2 Inhibitor for the Potential Treatment of Parkinson’s Disease von Kattar, Solomon D., Gulati, Anmol, Margrey, Kaila A., Keylor, Mitchell H., Ardolino, Michael, Yan, Xin, Johnson, Rebecca, Palte, Rachel L., McMinn, Spencer E., Nogle, Lisa, Su, Jing, Xiao, Dong, Piesvaux, Jennifer, Lee, Susi, Hegde, Laxminarayan G., Woodhouse, Janice D., Faltus, Robert, Moy, Lily Y., Xiong, Tina, Ciaccio, Paul J., Pearson, Kara, Patel, Mayankbhai, Otte, Karin M., Leyns, Cheryl E.G., Kennedy, Matthew E., Bennett, David Jonathan, DiMauro, Erin F., Fell, Matthew J., Fuller, Peter H.

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Biosecurity in Village and Other Free-Range Poultry—Trying to Square the Circle? von Otte, Joachim, Rushton, Jonathan, Rukambile, Elpidius, Alders, Robyn G.

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Discovery and Optimization of Potent, Selective, and Brain-Penetrant 1‑Heteroaryl‑1H‑Indazole LRRK2 Kinase Inhibitors for the Treatment of Parkinson’s Disease von Candito, David A., Simov, Vladimir, Gulati, Anmol, Kattar, Solomon, Chau, Ryan W., Lapointe, Blair T., Methot, Joey L., DeMong, Duane E., Graham, Thomas H., Kurukulasuriya, Ravi, Keylor, Mitchell H., Tong, Ling, Morriello, Gregori J., Acton, John J., Pio, Barbara, Liu, Weiguo, Scott, Jack D., Ardolino, Michael J., Martinot, Theodore A., Maddess, Matthew L., Yan, Xin, Gunaydin, Hakan, Palte, Rachel L., McMinn, Spencer E., Nogle, Lisa, Yu, Hongshi, Minnihan, Ellen C., Lesburg, Charles A., Liu, Ping, Su, Jing, Hegde, Laxminarayan G., Moy, Lily Y., Woodhouse, Janice D., Faltus, Robert, Xiong, Tina, Ciaccio, Paul, Piesvaux, Jennifer A., Otte, Karin M., Kennedy, Matthew E., Bennett, David Jonathan, DiMauro, Erin F., Fell, Matthew J., Neelamkavil, Santhosh, Wood, Harold B., Fuller, Peter H., Ellis, J. Michael

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The genomes of two key bumblebee species with primitive eusocial organization von Sadd, Ben M, Barribeau, Seth M, Bloch, Guy, de Graaf, Dirk C, Dearden, Peter, Elsik, Christine G, Gadau, Jürgen, Grimmelikhuijzen, Cornelis J P, Hasselmann, Martin, Lozier, Jeffrey D, Robertson, Hugh M, Smagghe, Guy, Stolle, Eckart, Van Vaerenbergh, Matthias, Waterhouse, Robert M, Bornberg-Bauer, Erich, Klasberg, Steffen, Bennett, Anna K, Câmara, Francisco, Guigó, Roderic, Hoff, Katharina, Mariotti, Marco, Munoz-Torres, Monica, Murphy, Terence, Santesmasses, Didac, Amdam, Gro V, Beckers, Matthew, Beye, Martin, Biewer, Matthias, Bitondi, Márcia M G, Blaxter, Mark L, Bourke, Andrew F G, Brown, Mark J F, Buechel, Severine D, Cameron, Rossanah, Cappelle, Kaat, Carolan, James C, Christiaens, Olivier, Ciborowski, Kate L, Clarke, David F, Colgan, Thomas J, Collins, David H, Cridge, Andrew G, Dalmay, Tamas, Dreier, Stephanie, du Plessis, Louis, Duncan, Elizabeth, Erler, Silvio, Evans, Jay, Falcon, Tiago, Flores, Kevin, Freitas, Flávia C P, Fuchikawa, Taro, Gempe, Tanja, Hartfelder, Klaus, Hauser, Frank, Helbing, Sophie, Humann, Fernanda C, Irvine, Frano, Jermiin, Lars S, Johnson, Claire E, Johnson, Reed M, Jones, Andrew K, Kadowaki, Tatsuhiko, Kidner, Jonathan H, Koch, Vasco, Köhler, Arian, Kraus, F Bernhard, Lattorff, H Michael G, Leask, Megan, Lockett, Gabrielle A, Mallon, Eamonn B, Antonio, David S Marco, Marxer, Monika, Meeus, Ivan, Moritz, Robin F A, Nair, Ajay, Näpflin, Kathrin, Nissen, Inga, Niu, Jinzhi, Nunes, Francis M F, Oakeshott, John G, Osborne, Amy, Otte, Marianne, Pinheiro, Daniel G, Rossié, Nina, Rueppell, Olav, Santos, Carolina G, Schmid-Hempel, Regula, Schmitt, Björn D, Schulte, Christina, Simões, Zilá L P, Soares, Michelle P M, Swevers, Luc, Winnebeck, Eva C, Wolschin, Florian, Yu, Na, Zdobnov, Evgeny M, Aqrawi, Peshtewani K, Blankenburg, Kerstin P

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Oxetane Promise Delivered: Discovery of Long-Acting IDO1 Inhibitors Suitable for Q3W Oral or Parenteral Dosing von Li, Derun, Sloman, David L, Achab, Abdelghani, Zhou, Hua, McGowan, Meredeth A, White, Catherine, Gibeau, Craig, Zhang, Hongjun, Pu, Qinglin, Bharathan, Indu, Hopkins, Brett, Liu, Kun, Ferguson, Heidi, Fradera, Xavier, Lesburg, Charles A, Martinot, Theodore A, Qi, Ji, Song, Zhiguo J, Yin, Jingjun, Zhang, Huangguang, Song, Licheng, Wan, Baoqiang, DAddio, Suzanne, Solban, Nicolas, Miller, J Richard, Zamlynny, Beata, Bass, Alan, Freeland, Elizabeth, Ykoruk, Bridget, Hilliard, Catherine, Ferraro, Jude, Zhai, Jin, Knemeyer, Ian, Otte, Karin M, Vincent, Stella, Sciammetta, Nunzio, Pasternak, Alexander, Bennett, David Jonathan, Han, Yongxin

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Discovery of Amino-cyclobutarene-derived Indoleamine-2,3-dioxygenase 1 (IDO1) Inhibitors for Cancer Immunotherapy von Zhang, Hongjun, Liu, Kun, Pu, Qinglin, Achab, Abdelghani, Ardolino, Michael J, Cheng, Mangeng, Deng, Yongqi, Doty, Amy C, Ferguson, Heidi, Fradera, Xavier, Knemeyer, Ian, Kurukulasuriya, Ravi, Lam, Yu-hong, Lesburg, Charles A, Martinot, Theodore A, McGowan, Meredeth A, Miller, J. Richard, Otte, Karin, Biju, Purakattle J, Sciammetta, Nunzio, Solban, Nicolas, Yu, Wensheng, Zhou, Hua, Wang, Xiao, Bennett, David Jonathan, Han, Yongxin

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