Spontaneous and Engineered Large Animal Models of Neurofibromatosis Type 1 von Osum, Sara H., Watson, Adrienne L., Largaespada, David A.

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PLX3397 treatment inhibits constitutive CSF1R-induced oncogenic ERK signaling, reduces tumor growth, and metastatic burden in osteosarcoma von Smeester, Branden A., Slipek, Nicholas J., Pomeroy, Emily J., Laoharawee, Kanut, Osum, Sara H., Larsson, Alex T., Williams, Kyle B., Stratton, Natalie, Yamamoto, Kenta, Peterson, Joseph J., Rathe, Susan K., Mills, Lauren J., Hudson, Wendy A., Crosby, Margaret R., Wang, Minjing, Rahrmann, Eric P., Moriarity, Branden S., Largaespada, David A.

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Combining nonsense mutation suppression therapy with nonsense-mediated decay inhibition in neurofibromatosis type 1 von Osum, Sara H., Oribamise, Eunice I., Corbière, Stanislas M.A.S., Taisto, Mandy, Jubenville, Tyler, Coutts, Alex, Kirstein, Mark N., Fisher, James, Moertel, Christopher, Du, Ming, Bedwell, David, Largaespada, David A., Watson, Adrienne L.

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Intestinal CD8αα IELs derived from two distinct thymic precursors have staggered ontogeny von Ruscher, Roland, Lee, S Thera, Salgado, Oscar C, Breed, Elise R, Osum, Sara H, Hogquist, Kristin A

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Ex vivo to in vivo model of malignant peripheral nerve sheath tumors for precision oncology von Larsson, Alex T, Bhatia, Himanshi, Calizo, Ana, Pollard, Kai, Zhang, Xiaochun, Conniff, Eric, Tibbitts, Justin F, Rono, Elizabeth, Cummins, Katherine, Osum, Sara H, Williams, Kyle B, Crampton, Alexandra L, Jubenville, Tyler, Schefer, Daniel, Yang, Kuangying, Lyu, Yang, Pino, James C, Bade, Jessica, Gross, John M, Lisok, Alla, Dehner, Carina A, Chrisinger, John S A, He, Kevin, Gosline, Sara J C, Pratilas, Christine A, Largaespada, David A, Wood, David K, Hirbe, Angela C

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Selumetinib normalizes Ras/MAPK signaling in clinically relevant neurofibromatosis type 1 minipig tissues in vivo von Osum, Sara H, Coutts, Alexander W, Duerre, Dylan J, Tschida, Barbara R, Kirstein, Mark N, Fisher, James, Bell, W Robert, Delpuech, Oona, Smith, Paul D, Widemann, Brigitte C, Moertel, Christopher L, Largaespada, David A, Watson, Adrienne L

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Intestinal CD8 alpha alpha IELs derived from two distinct thymic precursors have staggered ontogeny von Ruscher, Roland, Lee, S. Thera, Salgado, Oscar C., Breed, Elise R., Osum, Sara H., Hogquist, Kristin A.

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