PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis von Yin, Shasha, Liu, Liu, Brobbey, Charles, Palanisamy, Viswanathan, Ball, Lauren E., Olsen, Shaun K., Ostrowski, Michael C., Gan, Wenjian

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E2f3 in tumor macrophages promotes lung metastasis von Trikha, P, Sharma, N, Pena, C, Reyes, A, Pécot, T, Khurshid, S, Rawahneh, M, Moffitt, J, Stephens, J A, Fernandez, S A, Ostrowski, M C, Leone, G

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Erk1 and Erk2 regulate endothelial cell proliferation and migration during mouse embryonic angiogenesis von Srinivasan, Ruchika, Zabuawala, Tahera, Huang, Hong, Zhang, Jianying, Gulati, Parul, Fernandez, Soledad, Karlo, J Colleen, Landreth, Gary E, Leone, Gustavo, Ostrowski, Michael C

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Extracellular Vesicles Modulate the Glioblastoma Microenvironment via a Tumor Suppression Signaling Network Directed by miR-1 von BRONISZ, Agnieszka, YAN WANG, OSTROWSKI, Michael C, HOCHBERG, Fred, WEISSLEDER, Ralph, LAWLER, Sean E, CHIOCCA, E. Antonio, GODLEWSKI, Jakub, NOWICKI, Michal O, PERUZZI, Pierpaolo, ANSARI, Khairul I, OGAWA, Daisuke, BALAJ, Leonora, DE RIENZO, Gianluca, MINEO, Marco, NAKANO, Ichiro

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The splanchnic mesenchyme is the tissue of origin for pancreatic fibroblasts during homeostasis and tumorigenesis von Han, Lu, Wu, Yongxia, Fang, Kun, Sweeney, Sean, Roesner, Ulyss K., Parrish, Melodie, Patel, Khushbu, Walter, Tom, Piermattei, Julia, Trimboli, Anthony, Lefler, Julia, Timmers, Cynthia D., Yu, Xue-Zhong, Jin, Victor X., Zimmermann, Michael T., Mathison, Angela J., Urrutia, Raul, Ostrowski, Michael C., Leone, Gustavo

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TNF inhibits Notch-1 in skeletal muscle cells by Ezh2 and DNA methylation mediated repression: implications in duchenne muscular dystrophy von Acharyya, Swarnali, Sharma, Sudarshana M, Cheng, Alfred S, Ladner, Katherine J, He, Wei, Kline, William, Wang, Huating, Ostrowski, Michael C, Huang, Tim H, Guttridge, Denis C

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Ambient Air Pollution Exaggerates Adipose Inflammation and Insulin Resistance in a Mouse Model of Diet-Induced Obesity von QINGHUA SUN, PEIBIN YUE, BROOK, Robert D, MOFFATT-BRUCE, Susan D, LUNG CHI CHEN, RAJAGOPALAN, Sanjay, DEIULIIS, Jeffrey A, LUMENG, Carey N, KAMPFRATH, Thomas, MIKOLAJ, Michael B, YING CAI, OSTROWSKI, Michael C, BO LU, PARTHASARATHY, Sampath

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Csf1r -mApple Transgene Expression and Ligand Binding In Vivo Reveal Dynamics of CSF1R Expression within the Mononuclear Phagocyte System von Hawley, Catherine A, Rojo, Rocio, Raper, Anna, Sauter, Kristin A, Lisowski, Zofia M, Grabert, Kathleen, Bain, Calum C, Davis, Gemma M, Louwe, Pieter A, Ostrowski, Michael C, Hume, David A, Pridans, Clare, Jenkins, Stephen J

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Optimization of a mouse model of pancreatic cancer to simulate the human phenotypes of metastasis and cachexia von Spadafora, Victoria, Pryce, Benjamin R, Oles, Alexander, Talbert, Erin E, Romeo, Martin, Vaena, Silvia, Berto, Stefano, Ostrowski, Michael C, Wang, David J, Guttridge, Denis C

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NFATc1 in mice represses osteoprotegerin during osteoclastogenesis and dissociates systemic osteopenia from inflammation in cherubism von Aliprantis, Antonios O, Ueki, Yasuyoshi, Sulyanto, Rosalyn, Park, Arnold, Sigrist, Kirsten S, Sharma, Sudarshana M, Ostrowski, Michael C, Olsen, Bjorn R, Glimcher, Laurie H

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PTEN expression by an oncolytic herpesvirus directs T-cell mediated tumor clearance von Russell, Luke, Swanner, Jessica, Jaime-Ramirez, Alena Cristina, Wang, Yufeng, Sprague, Alex, Banasavadi-Siddegowda, Yeshavanth, Yoo, Ji Young, Sizemore, Gina M., Kladney, Raleigh, Zhang, Jianying, Lehman, Norman L., Ostrowski, Michael C, Hong, Bangxing, Caligiuri, Michael, Yu, Jianhua, Kaur, Balveen

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White Electrophosphorescence from Semiconducting Polymer Blends von Gong, X., Ma, W., Ostrowski, J. C., Bazan, G. C., Moses, D., Heeger, A. J.

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Stromal PTEN Regulates Extracellular Matrix Organization in the Mammary Gland von Jones, Caitlin E., Hammer, Anisha M., Cho, YouJin, Sizemore, Gina M., Cukierman, Edna, Yee, Lisa D., Ghadiali, Samir N., Ostrowski, Michael C., Leight, Jennifer L.

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Generation of a pancreatic cancer model using a Pdx1-Flp recombinase knock-in allele von Wu, Jinghai, Liu, Xin, Nayak, Sunayana G, Pitarresi, Jason R, Cuitiño, Maria C, Yu, Lianbo, Hildreth, 3rd, Blake E, Thies, Katie A, Schilling, Daniel J, Fernandez, Soledad A, Leone, Gustavo, Ostrowski, Michael C

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Direct Evidence for Epithelial-Mesenchymal Transitions in Breast Cancer von TRIMBOLI, Anthony J, FUKINO, Koichi, OSTROWSKI, Michael C, LEONE, Gustavo, DE BRUIN, Alain, GUO WEI, LEI SHEN, TANNER, Stephan M, CREASAP, Nicholas, ROSOL, Thomas J, ROBINSON, Michael L, ENG, Charis

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Endothelial-specific deletion of Ets-1 attenuates Angiotensin II-induced cardiac fibrosis via suppression of endothelial-to-mesenchymal transition von Xu, Lian, Fu, Mengxia, Chen, Dongrui, Han, Weiqing, Ostrowski, Michael C, Grossfeld, Paul, Gao, Pingjin, Ye, Maoqing

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Inhibition of Jak/STAT signaling reduces the activation of pancreatic stellate cells in vitro and limits caerulein-induced chronic pancreatitis in vivo von Komar, Hannah M., Serpa, Gregory, Kerscher, Claire, Schwoegl, Erin, Mace, Thomas A., Jin, Ming, Yang, Ming-Chen, Chen, Ching-Shih, Bloomston, Mark, Ostrowski, Michael C., Hart, Phil A., Conwell, Darwin L., Lesinski, Gregory B.

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Two Distinct E2F Transcriptional Modules Drive Cell Cycles and Differentiation von Cuitiño, Maria C., Pécot, Thierry, Sun, Daokun, Kladney, Raleigh, Okano-Uchida, Takayuki, Shinde, Neelam, Saeed, Resham, Perez-Castro, Antonio J., Webb, Amy, Liu, Tom, Bae, Soo In, Clijsters, Linda, Selner, Nicholas, Coppola, Vincenzo, Timmers, Cynthia, Ostrowski, Michael C., Pagano, Michele, Leone, Gustavo

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CSF1-ETS2-induced microRNA in myeloid cells promote metastatic tumor growth von Mathsyaraja, H, Thies, K, Taffany, D A, Deighan, C, Liu, T, Yu, L, Fernandez, S A, Shapiro, C, Otero, J, Timmers, C, Lustberg, M B, Chalmers, J, Leone, G, Ostrowski, M C

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Synthetic Lethality of PARP Inhibition and Ionizing Radiation is p53-dependent von Sizemore, Steven T, Mohammad, Rahman, Sizemore, Gina M, Nowsheen, Somaira, Yu, Hao, Ostrowski, Michael C, Chakravarti, Arnab, Xia, Fen

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