Forkhead Transcription Factors Establish Origin Timing and Long-Range Clustering in S. cerevisiae von Knott, Simon R.V., Peace, Jared M., Ostrow, A. Zachary, Gan, Yan, Rex, Alexandra E., Viggiani, Christopher J., Tavaré, Simon, Aparicio, Oscar M.

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Fkh1 and Fkh2 bind multiple chromosomal elements in the S. cerevisiae genome with distinct specificities and cell cycle dynamics von Ostrow, A Zachary, Nellimoottil, Tittu, Knott, Simon R V, Fox, Catherine A, Tavaré, Simon, Aparicio, Oscar M

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ChIP-Seq to Analyze the Binding of Replication Proteins to Chromatin von Ostrow, A. Zachary, Viggiani, Christopher J., Aparicio, Jennifer G., Aparicio, Oscar M.

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Conserved forkhead dimerization motif controls DNA replication timing and spatial organization of chromosomes in S. cerevisiae von Ostrow, A. Zachary, Kalhor, Reza, Gan, Yan, Villwock, Sandra K., Linke, Christian, Barberis, Matteo, Chen, Lin, Aparicio, Oscar M.

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Identification of Fkh1 and Fkh2 binding site variants associated with dynamically bound DNA elements including replication origins von Ostrow, A. Zachary, Aparicio, Oscar M.

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Forkhead (Fox) transcription factors open a new dimension in understanding the epigenetic control of replication origins in S. cerevisiae von Aparicio, Oscar, Knott, Simon R. V., Ostrow, Zachary A., Peace, Jared M., Gan, Yan, Kalhor, Reza, Chen, Lin, Tavaré, Simon

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Fkh1 and Fkh2 Bind Multiple Chromosomal Elements in the S. cerevisiae Genome with Distinct Specificities and Cell Cycle Dynamics: e87647 von Ostrow, A Zachary, Nellimoottil, Tittu, Knott, Simon RV, Fox, Catherine A, Tavare, Simon, Aparicio, Oscar M

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Postmortem Cortex Samples Identify Distinct Molecular Subtypes of ALS: Retrotransposon Activation, Oxidative Stress, and Activated Glia von Tam, Oliver H., Rozhkov, Nikolay V., Shaw, Regina, Kim, Duyang, Hubbard, Isabel, Fennessey, Samantha, Propp, Nadia, Phatnani, Hemali, Kwan, Justin, Sareen, Dhruv, Broach, James R., Simmons, Zachary, Arcila-Londono, Ximena, Lee, Edward B., Van Deerlin, Vivianna M., Shneider, Neil A., Fraenkel, Ernest, Ostrow, Lyle W., Baas, Frank, Zaitlen, Noah, Berry, James D., Malaspina, Andrea, Fratta, Pietro, Cox, Gregory A., Thompson, Leslie M., Finkbeiner, Steve, Dardiotis, Efthimios, Miller, Timothy M., Chandran, Siddharthan, Pal, Suvankar, Hornstein, Eran, MacGowan, Daniel J., Heiman-Patterson, Terry, Hammell, Molly G., Patsopoulos, Nikolaos.A., Butovsky, Oleg, Dubnau, Joshua, Nath, Avindra, Bowser, Robert, Harms, Matt, Aronica, Eleonora, Poss, Mary, Phillips-Cremins, Jennifer, Crary, John, Atassi, Nazem, Lange, Dale J., Adams, Darius J., Stefanis, Leonidas, Gotkine, Marc, Baloh, Robert, Babu, Suma, Raj, Towfique, Paganoni, Sabrina, Shalem, Ophir, Smith, Colin, Zhang, Bin, Harris, Brent T., Fagegaltier, Delphine, Harris, Brent T., Ostrow, Lyle W., Phatnani, Hemali, Ravits, John, Dubnau, Josh, Gale Hammell, Molly

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Broadly Applicable Control Approaches Improve Accuracy of ChIP-Seq Data von Petrie, Meghan V, He, Yiwei, Gan, Yan, Ostrow, Andrew Zachary, Aparicio, Oscar M

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TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A von Brown, Anna-Leigh, Wilkins, Oscar G., Keuss, Matthew J., Hill, Sarah E., Zanovello, Matteo, Lee, Weaverly Colleen, Bampton, Alexander, Lee, Flora C. Y., Masino, Laura, Qi, Yue A., Bryce-Smith, Sam, Gatt, Ariana, Hallegger, Martina, Fagegaltier, Delphine, Phatnani, Hemali, Newcombe, Jia, Gustavsson, Emil K., Seddighi, Sahba, Reyes, Joel F., Coon, Steven L., Ramos, Daniel, Schiavo, Giampietro, Fisher, Elizabeth M. C., Raj, Towfique, Secrier, Maria, Lashley, Tammaryn, Ule, Jernej, Buratti, Emanuele, Humphrey, Jack, Ward, Michael E., Fratta, Pietro

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Unexpected similarities between C9ORF72 and sporadic forms of ALS/FTD suggest a common disease mechanism von Conlon, Erin G, Fagegaltier, Delphine, Agius, Phaedra, Davis-Porada, Julia, Gregory, James, Hubbard, Isabel, Kang, Kristy, Kim, Duyang, Phatnani, Hemali, Shneider, Neil A, Manley, James L

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A framework for sharing of clinical and genetic data for precision medicine applications von Elhussein, Ahmed, Baymuradov, Ulugbek, Elhadad, Noémie, Natarajan, Karthik, Gürsoy, Gamze

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Author Correction: TDP-43 loss and ALS-risk SNPs drive mis-splicing and depletion of UNC13A von Brown, Anna-Leigh, Wilkins, Oscar G., Keuss, Matthew J., Hill, Sarah E., Zanovello, Matteo, Lee, Weaverly Colleen, Bampton, Alexander, Lee, Flora C. Y., Masino, Laura, Qi, Yue A., Bryce-Smith, Sam, Gatt, Ariana, Hallegger, Martina, Fagegaltier, Delphine, Phatnani, Hemali, Newcombe, Jia, Gustavsson, Emil K., Seddighi, Sahba, Reyes, Joel F., Coon, Steven L., Ramos, Daniel, Schiavo, Giampietro, Fisher, Elizabeth M. C., Raj, Towfique, Secrier, Maria, Lashley, Tammaryn, Ule, Jernej, Buratti, Emanuele, Humphrey, Jack, Ward, Michael E., Fratta, Pietro

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Rare variant analyses validate known ALS genes in a multi-ethnic population and identifies ANTXR2 as a candidate in PLS von Pottinger, Tess D, Motelow, Joshua E, Povysil, Gundula, Moreno, Cristiane A Martins, Ren, Zhong, Phatnani, Hemali, Aitman, Timothy J, Santoyo-Lopez, Javier, Mitsumoto, Hiroshi, Goldstein, David B, Harms, Matthew B

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NOS1AP is a novel molecular target and critical factor in TDP-43 pathology von Cappelli, Sara, Spalloni, Alida, Feiguin, Fabian, Visani, Giulia, Šušnjar, Urša, Brown, Anna-Leigh, De Bardi, Marco, Borsellino, Giovanna, Secrier, Maria, Phatnani, Hemali, Romano, Maurizio, Fratta, Pietro, Longone, Patrizia, Buratti, Emanuele

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The cycad genotoxin methylazoxymethanol, linked to Guam ALS/PDC, induces transcriptional mutagenesis von Verheijen, Bert M, Chung, Claire, Thompson, Ben, Kim, Hyunjin, Nakahara, Asa, Anink, Jasper J, Mills, James D, Lee, Jeong H, Aronica, Eleonora, Oyanagi, Kiyomitsu, Kakita, Akiyoshi, Gout, Jean-Francois, Vermulst, Marc

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An integrated multi-omic analysis of iPSC-derived motor neurons from C9ORF72 ALS patients von Phatnani, Hemali, Kwan, Justin, Sareen, Dhruv, Broach, James R., Simmons, Zachary, Arcila-Londono, Ximena, Lee, Edward B., Van Deerlin, Vivianna M., Shneider, Neil A., Fraenkel, Ernest, Ostrow, Lyle W., Baas, Frank, Zaitlen, Noah, Malaspina, Andrea, Fratta, Pietro, Cox, Gregory A., Thompson, Leslie M., Finkbeiner, Steve, Dardiotis, Efthimios, Chandran, Siddharthan, Pal, Suvankar, Hornstein, Eran, MacGowan, Daniel J., Heiman-Patterson, Terry, Hammell, Molly G., Patsopoulos, Nikolaos.A., Butovsky, Oleg, Dubnau, Joshua, Nath, Avindra, Bowser, Robert, Harms, Matt, Poss, Mary, Phillips-Cremins, Jennifer, Crary, John, Atassi, Nazem, Lange, Dale J., Adams, Darius J., Stefanis, Leonidas, Gotkine, Marc, Baloh, Robert H., Babu, Suma, Raj, Towfique, Paganoni, Sabrina, Shalem, Ophir, Smith, Colin, Zhang, Bin, Harris, Brent, Broce, Iris, Drory, Vivian, Ravits, John, McMillan, Corey, Menon, Vilas, Wu, Lani, Altschuler, Steven, Li, Jonathan, Lim, Ryan G., Kaye, Julia A., Dardov, Victoria, Coyne, Alyssa N., Wu, Jie, Milani, Pamela, Cheng, Andrew, Thompson, Terri G., Ornelas, Loren, Frank, Aaron, Adam, Miriam, Banuelos, Maria G., Casale, Malcolm, Cox, Veerle, Escalante-Chong, Renan, Daigle, J. Gavin, Gomez, Emilda, Hayes, Lindsey, Holewenski, Ronald, Lei, Susan, Lenail, Alex, Lima, Leandro, Mandefro, Berhan, Matlock, Andrea, Panther, Lindsay, Patel-Murray, Natasha Leanna, Pham, Jacqueline, Ramamoorthy, Divya, Sachs, Karen, Shelley, Brandon, Stocksdale, Jennifer, Trost, Hannah, Wilhelm, Mark, Venkatraman, Vidya, Wassie, Brook T., Wyman, Stacia, Yang, Stephanie, Van Eyk, Jennifer E., Lloyd, Thomas E., Finkbeiner, Steven, Fraenkel, Ernest, Rothstein, Jeffrey D., Sareen, Dhruv, Svendsen, Clive N., Thompson, Leslie M.

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Mechanism-free repurposing of drugs for C9orf72-related ALS/FTD using large-scale genomic data von Saez-Atienzar, Sara, Souza, Cleide dos Santos, Chia, Ruth, Burciu, Camelia, Gibbs, J. Raphael, Jones, Ashley, Dewan, Ramita, Pensato, Viviana, Corrado, Lucia, van Vugt, Joke J.F.A., van Rheenen, Wouter, Camu, William, Cusi, Daniele, Ding, Jinhui, Drepper, Carsten, Drory, Vivian E., Gerhard, Glenn, Gibbs, J. Raphael, Gibson, Summer B., Hardy, John, Landers, John E., Guissart, Claire, MacGowan, Daniel JL, Mouzat, Kevin, Myllykangas, Liisa, Pulst, Stefan M., Ravits, John M., Renton, Alan E., Rogaeva, Ekaterina, Salvi, Erika, Scholz, Sonja W., Tienari, Pentti J., Valori, Miko, Van Damme, Philip, Zinman, Lorne, Barberis, Marco, Bersano, Enrica, Bisogni, Giulia, Canale, Fabrizio, Carrera, Paola, Casale, Federico, Colletti, Tiziana, Conforti, Francesca L., Ferrarese, Carlo, Greco, Lucia, La Bella, Vincenzo, Marrosu, Maria Giovanna, Messina, Sonia, Moglia, Cristina, Passaniti, Carla, Petrelli, Cristina, Petrucci, Antonio, Russo, Massimo, Salvi, Fabrizio, Santarelli, Marialuisa, Sideri, Riccardo, Vasta, Rosario, Zucchi, Elisabetta, Ticozzi, Nicola, Tiloca, Cinzia, Peverelli, Silvia, Taroni, Franco, Pensato, Viviana, Castellotti, Barbara, Comi, Giacomo P., Corrado, Lucia, Sorarù, Gianni, Corcia, Philippe, Vourc'h, Patrick, Gotkine, Marc, Drory, Vivian, Berg, Leonard H., Andersen, Peter, Tiloca, Cinzia, Verde, Federico, Al Khleifat, Ahmad, Piccinelli, Stefano Cotti, Padovani, Alessandro, Calvo, Andrea, Canosa, Antonio, Lunetta, Christian, Cardinali, Patrizio, Scarpini, Elio, Comi, Giacomo P., Pinter, Giuseppe Lauria, Taroni, Franco, Bella, Eleonora Dalla, Adeleye, Adelani, McGrath Martinez, Elisa, Soltis, Anthony R., Sukumar, Gauthaman, Viollet, Coralie, McLaughlin, Russell, Sorarù, Gianni, Ratti, Antonia, Doucet-O’Hare, Tara, Nath, Avindra, Siciliano, Gabriele, Glass, Jonathan D., Ferraiuolo, Laura

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SPATIAL OMICS PLATFORMS AND SYSTEMS von SHULTZABERGER, Sarah Munchel, VERMAAS, Eric Hans, MANZO, Andrea, PRICE, Andrew J, KARUNAKARAN, Aathavan, KAPER, Fiona, OSTROW, Andrew Zachary, MANDELL, Jeffrey G, WHITE, Adam, BRODIN, Jeffrey, FISHER, Jeffrey S

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SPATIAL OMICS PLATFORMS AND SYSTEMS von SHULTZABERGER, Sarah Munchel, VERMAAS, Eric Hans, MANZO, Andrea, PRICE, Andrew J, KARUNAKARAN, Aathavan, KAPER, Fiona, OSTROW, Andrew Zachary, MANDELL, Jeffrey G, WHITE, Adam, BRODIN, Jeffrey, FISHER, Jeffrey S

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