Induction of trained immunity by influenza vaccination - impact on COVID-19 von Debisarun, Priya A, Gössling, Katharina L, Bulut, Ozlem, Kilic, Gizem, Zoodsma, Martijn, Liu, Zhaoli, Oldenburg, Marina, Rüchel, Nadine, Zhang, Bowen, Xu, Cheng-Jian, Struycken, Patrick, Koeken, Valerie A. C. M, Domínguez-Andrés, Jorge, Moorlag, Simone J. C. F. M, Taks, Esther, Ostermann, Philipp N, Müller, Lisa, Schaal, Heiner, Adams, Ortwin, Borkhardt, Arndt, ten Oever, Jaap, van Crevel, Reinout, Li, Yang, Netea, Mihai G

Volltext

Deep Transfer Learning Approach for Automatic Recognition of Drug Toxicity and Inhibition of SARS-CoV-2 von Werner, Julia, Kronberg, Raphael M, Stachura, Pawel, Ostermann, Philipp N, Müller, Lisa, Schaal, Heiner, Bhatia, Sanil, Kather, Jakob N, Borkhardt, Arndt, Pandyra, Aleksandra A, Lang, Karl S, Lang, Philipp A

Volltext

SARS‐CoV‐2 targets neurons of 3D human brain organoids von Ramani, Anand, Müller, Lisa, Ostermann, Philipp N, Gabriel, Elke, Abida‐Islam, Pranty, Müller‐Schiffmann, Andreas, Mariappan, Aruljothi, Goureau, Olivier, Gruell, Henning, Walker, Andreas, Andrée, Marcel, Hauka, Sandra, Houwaart, Torsten, Dilthey, Alexander, Wohlgemuth, Kai, Omran, Heymut, Klein, Florian, Wieczorek, Dagmar, Adams, Ortwin, Timm, Jörg, Korth, Carsten, Schaal, Heiner, Gopalakrishnan, Jay

Volltext

Multi-Omics Integration Reveals Only Minor Long-Term Molecular and Functional Sequelae in Immune Cells of Individuals Recovered From COVID-19 von Liu, Zhaoli, Kilic, Gizem, Li, Wenchao, Bulut, Ozlem, Gupta, Manoj Kumar, Zhang, Bowen, Qi, Cancan, Peng, He, Tsay, Hsin-Chieh, Soon, Chai Fen, Mekonnen, Yonatan Ayalew, Ferreira, Anaísa Valido, van der Made, Caspar I, van Cranenbroek, Bram, Koenen, Hans J P M, Simonetti, Elles, Diavatopoulos, Dimitri, de Jonge, Marien I, Müller, Lisa, Schaal, Heiner, Ostermann, Philipp N, Cornberg, Markus, Eiz-Vesper, Britta, van de Veerdonk, Frank, van Crevel, Reinout, Joosten, Leo A B, Domínguez-Andrés, Jorge, Xu, Cheng-Jian, Netea, Mihai G, Li, Yang

Volltext

Cellular rejuvenation to combat HIV-1-related neurocognitive impairment von Ostermann, Philipp N., Evering, Teresa H.

Volltext

Design of D-Amino Acids SARS-CoV-2 Main Protease Inhibitors Using the Cationic Peptide from Rattlesnake Venom as a Scaffold von Eberle, Raphael J, Gering, Ian, Tusche, Markus, Ostermann, Philipp N, Müller, Lisa, Adams, Ortwin, Schaal, Heiner, Olivier, Danilo S, Amaral, Marcos S, Arni, Raghuvir K, Willbold, Dieter, Coronado, Mônika A

Volltext

MMR vaccination induces trained immunity via functional and metabolic reprogramming of γδ T cells von Röring, Rutger J, Debisarun, Priya A, Botey-Bataller, Javier, Suen, Tsz Kin, Bulut, Ozlem, Kilic, Gizem, Koeken, Valerie Acm, Sarlea, Andrei, Bahrar, Harsh, Dijkstra, Helga, Lemmers, Heidi, Gössling, Katharina L, Rüchel, Nadine, Ostermann, Philipp N, Müller, Lisa, Schaal, Heiner, Adams, Ortwin, Borkhardt, Arndt, Ariyurek, Yavuz, de Meijer, Emile J, Kloet, Susan L, Ten Oever, Jaap, Placek, Katarzyna, Li, Yang, Netea, Mihai G

Volltext

Humoral response to SARS‐CoV‐2 and seasonal coronaviruses in COVID‐19 patients von Adams, Ortwin, Andrée, Marcel, Rabl, Denise, Ostermann, Philipp N., Schaal, Heiner, Lehnert, Erik, Ackerstaff, Stefanie, Müller, Lisa, Fischer, Johannes C.

Volltext

Crystal Structure of an Activation Intermediate of Cathepsin E von Ostermann, Nils, Gerhartz, Bernd, Worpenberg, Susanne, Trappe, Jörg, Eder, Jörg

Volltext

Autodesk Maya 2015: 3D-Animation vom Concept zum Final von Ostermann, Alexander N

Volltext

Induction of trained immunity by influenza vaccination - impact on COVID-19 von Priya A Debisarun, Katharina L Gössling, Ozlem Bulut, Gizem Kilic, Martijn Zoodsma, Zhaoli Liu, Marina Oldenburg, Nadine Rüchel, Bowen Zhang, Cheng-Jian Xu, Patrick Struycken, Valerie A C M Koeken, Jorge Domínguez-Andrés, Simone J C F M Moorlag, Esther Taks, Philipp N Ostermann, Lisa Müller, Heiner Schaal, Ortwin Adams, Arndt Borkhardt, Jaap Ten Oever, Reinout van Crevel, Yang Li, Mihai G Netea

Volltext

MMR vaccination induces trained immunity via functional and metabolic reprogramming of [gamma][delta] T cells von Roring, Rutger J, Debisarun, Priya A, Botey-Bataller, Javier, Suen, Tsz Kin, Bulut, Ozlem, Kilic, Gizem, Koeken, Valerie A.C.M, Sarlea, Andrei, Bahrar, Harsh, Dijkstra, Helga, Lemmers, Heidi, Gossling, Katharina L, Ruchel, Nadine, Ostermann, Philipp N, Muller, Lisa, Schaal, Heiner, Adams, Ortwin, Borkhardt, Arndt, Ariyurek, Yavuz, de Meijer, Emile J, Kloet, Susan L, Oever, Jaap ten, Placek, Katarzyna, Li, Yang, Netea, Mihai G

Volltext

Crystal Structure of Human BACE2 in Complex with a Hydroxyethylamine Transition-state Inhibitor von Ostermann, Nils, Eder, Jörg, Eidhoff, Ulf, Zink, Florence, Hassiepen, Ulrich, Worpenberg, Susanne, Maibaum, Jürgen, Simic, Oliver, Hommel, Ulrich, Gerhartz, Bernd

Volltext

Insights into the phosphoryltransfer mechanism of human thymidylate kinase gained from crystal structures of enzyme complexes along the reaction coordinate von Ostermann, Nils, Schlichting, Ilme, Brundiers, Ralf, Konrad, Manfred, Reinstein, Jochen, Veit, Thomas, Goody, Roger S, Lavie, Arnon

Volltext

Structures of Human Thymidylate Kinase in Complex with Prodrugs:  Implications for the Structure-Based Design of Novel Compounds von Ostermann, Nils, Segura-Peña, Dario, Meier, Chris, Veit, Thomas, Monnerjahn, Christian, Konrad, Manfred, Lavie, Arnon

Volltext

Structural Basis for Efficient Phosphorylation of 3′-azidothymidine Monophosphate by Escherichia coli Thymidylate Kinase von Lavie, Arnon, Ostermann, Nils, Brundiers, Ralf, Goody, Roger S., Reinstein, Jochen, Konrad, Manfred, Schlichting, Ilme

Volltext

Potentiating AZT activation: structures of wild-type and mutant human thymidylate kinase suggest reasons for the mutants' improved kinetics with the HIV prodrug metabolite AZTMP von Ostermann, N, Lavie, A, Padiyar, S, Brundiers, R, Veit, T, Reinstein, J, Goody, R S, Konrad, M, Schlichting, I

Volltext

Modifying Human Thymidylate Kinase to Potentiate Azidothymidine Activation von Brundiers, R, Lavie, A, Veit, T, Reinstein, J, Schlichting, I, Ostermann, N, Goody, R S, Konrad, M

Volltext

MMR vaccination induces trained immunity via functional and metabolic reprogramming of [gamma][delta] T cells von Roring, Rutger J, Debisarun, Priya A, Botey-Bataller, Javier, Suen, Tsz Kin, Bulut, Ozlem, Kilic, Gizem, Koeken, Valerie A.C.M, Sarlea, Andrei, Bahrar, Harsh, Dijkstra, Helga, Lemmers, Heidi, Gossling, Katharina L, Ruchel, Nadine, Ostermann, Philipp N, Muller, Lisa, Schaal, Heiner, Adams, Ortwin, Borkhardt, Arndt, Ariyurek, Yavuz, de Meijer, Emile J, Kloet, Susan L, Oever, Jaap ten, Placek, Katarzyna, Li, Yang, Netea, Mihai G

Volltext

Induction of trained immunity by influenza vaccination - impact on COVID-19 von Debisarun, Priya A, Gössling, Katharina L, Bulut, Ozlem, Kilic, Gizem, Zoodsma, Ma, Liu, Zhaoli, Oldenburg, Marina, Rüchel, Nadine, Zhang, Bowen, Xu, Cheng-Jian, Struycken, Patrick, Koeken, Valerie A. C. M, Domínguez-Andrés, Jorge, Moorlag, Simone J. C. F. M, Taks, Esther, Ostermann, Philipp N, Müller, Lisa, Schaal, Heiner, Adams, Ortwin, Borkhardt, Arndt, ten Oever, Jaap, van Crevel, Reinout, Li, Yang, Netea, Mihai G

Volltext