Myosin modulators: emerging approaches for the treatment of cardiomyopathies and heart failure von Day, Sharlene M, Tardiff, Jil C, Ostap, E Michael

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Molecular to organismal chirality is induced by the conserved myosin 1D von Lebreton, G, Géminard, C, Lapraz, F, Pyrpassopoulos, S, Cerezo, D, Spéder, P, Ostap, E M, Noselli, S

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Modulation of Kinesin’s Load-Bearing Capacity by Force Geometry and the Microtubule Track von Pyrpassopoulos, Serapion, Shuman, Henry, Ostap, E. Michael

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Inherent Force-Dependent Properties of β-Cardiac Myosin Contribute to the Force-Velocity Relationship of Cardiac Muscle von Greenberg, Michael J., Shuman, Henry, Ostap, E. Michael

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WHAMM Directs the Arp2/3 Complex to the ER for Autophagosome Biogenesis through an Actin Comet Tail Mechanism von Kast, David J., Zajac, Allison L., Holzbaur, Erika L.F., Ostap, E. Michael, Dominguez, Roberto

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Modulation of Kinesin's Load-Bearing Capacity by Force Geometry and the Microtubule Track von Pyrpassopoulos, Serapion, Shuman, Henry, Ostap, E Michael

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Myosin-I molecular motors at a glance von McIntosh, Betsy B, Ostap, E Michael

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Local Cytoskeletal and Organelle Interactions Impact Molecular-Motor-Driven Early Endosomal Trafficking von Zajac, Allison L., Goldman, Yale E., Holzbaur, Erika L.F., Ostap, E. Michael

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Single molecule mechanics resolves the earliest events in force generation by cardiac myosin von Woody, Michael S, Winkelmann, Donald A, Capitanio, Marco, Ostap, E Michael, Goldman, Yale E

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The regulatory protein 14-3-3β binds to the IQ motifs of myosin-IC independent of phosphorylation von Ji, Huan-Hong, Ostap, E. Michael

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Positive cardiac inotrope omecamtiv mecarbil activates muscle despite suppressing the myosin working stroke von Woody, Michael S., Greenberg, Michael J., Barua, Bipasha, Winkelmann, Donald A., Goldman, Yale E., Ostap, E. Michael

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Myosin-1C differentially displaces tropomyosin isoforms altering their inhibition of motility von Pollard, Luther W., Boczkowska, Malgorzata, Dominguez, Roberto, Ostap, E. Michael

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High-resolution cryo-EM structures of actin-bound myosin states reveal the mechanism of myosin force sensing von Mentes, Ahmet, Huehn, Andrew, Liu, Xueqi, Zwolak, Adam, Dominguez, Roberto, Shuman, Henry, Ostap, E. Michael, Sindelar, Charles V.

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2,3-Butanedione monoxime (BDM) as a myosin inhibitor von Ostap, E Michael

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Myosin with hypertrophic cardiac mutation R712L has a decreased working stroke which is rescued by omecamtiv mecarbil von Snoberger, Aaron, Barua, Bipasha, Atherton, Jennifer L, Shuman, Henry, Forgacs, Eva, Goldman, Yale E, Winkelmann, Donald A, Ostap, E Michael

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Microtubule Dumbbells to Assess the Effect of Force Geometry on Single Kinesin Motors von Pyrpassopoulos, Serapion, Shuman, Henry, Ostap, E. Michael

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Adhesion force and attachment lifetime of the KIF16B-PX domain interaction with lipid membranes von Pyrpassopoulos, Serapion, Shuman, Henry, Ostap, E Michael

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Drosophila class-I myosins that can impact left-right asymmetry have distinct ATPase kinetics von Báez-Cruz, Faviolla A., Ostap, E. Michael

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A Perspective on the Role of Myosins as Mechanosensors von Greenberg, Michael J., Arpağ, Göker, Tüzel, Erkan, Ostap, E. Michael

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CARMIL leading edge localization depends on a non-canonical PH domain and dimerization von Zwolak, Adam, Yang, Changsong, Feeser, Elizabeth A., Michael Ostap, E., Svitkina, Tatyana, Dominguez, Roberto

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