Diagnostic criteria for apathy in clinical practice von Mulin, E., Leone, E., Dujardin, K., Delliaux, M., Leentjens, A., Nobili, F., Dessi, B., Tible, O., Agüera-Ortiz, L., Osorio, R. S., Yessavage, J., Dachevsky, D., Verhey, F.RJ, Jentoft, Alfonso J. Cruz, Blanc, O., Llorca, P.M, Robert, P. H.

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Reduced glucose uptake and Aβ in brain regions with hyperintensities in connected white matter von Glodzik, L., Kuceyeski, A., Rusinek, H., Tsui, W., Mosconi, L., Li, Y., Osorio, R.S., Williams, S., Randall, C., Spector, N., McHugh, P., Murray, J., Pirraglia, E., Vallabhajosula, S., Raj, A., de Leon, M.J.

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0268 ROLE OF INTERMITTENT HYPOXIA AND SLEEP FRADMENTATION FROM OSA DURING SLOW WAVE SLEEP ON SPATIAL MEMORY von Kam, K, Castillo, B, Chua, N, Sanders, H, Rapoport, DM, Ayappa, I, Osorio, RS, Varga, AW

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Early Detection of Alzheimer’s Disease with PET Imaging von Berti, V., Osorio, R.S., Mosconi, L., Li, Y., De Santi, S., de Leon, M.J.

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0758 REDUCED SPINDLE FREQUENCY AND DENSITY IN STAGE 2 NREM SLEEP IS ASSOCIATED WITH INCREASED CSF P-TAU IN COGNITIVELY NORMAL ELDERLY von Sharma, RA, Kam, K, Parekh, A, Uribe-Cano, S, Tweardy, S, Bubu, OM, Ayappa, I, Rapoport, DM, Varga, AW, Osorio, RS

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1153 DISTURBED SLEEP IS ASSOCIATED WITH CHANGES IN ALZHEIMER’S DISEASE (AD) BIOMARKERS PREDICTIVE OF PERSONS THAT ULTIMATELY DEVELOP AD: FINDINGS FROM SUBGROUP META-ANALYSIS ON SLE... von Bubu, OM, Bakke, JL, Hogan, MM, Umasabor-Bubu, OQ, Mukhtar, F, Ram, SA, Osorio, RS

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Imaging and Cerebrospinal Fluid Biomarkers in the Search for Alzheimer's Disease Mechanisms von Osorio, R.S., Pirraglia, E., Gumb, T., Mantua, J., Ayappa, I., Williams, S., Mosconi, L., Glodzik, L., de Leon, M.J.

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The concept of FDG-PET endophenotype in Alzheimer’s disease von During, Emmanuel H., Osorio, R. S., Elahi, F. M., Mosconi, L., de Leon, M. J.

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Association of CSF sTREM2, a marker of microglia activation, with cholinergic basal forebrain volume in major depressive disorder von Teipel, Stefan, Bruno, Davide, Plaska, Chelsea Reichert, Heslegrave, Amanda, Ramos-Cejudo, Jaime, Osorio, Ricardo S., Zetterberg, Henrik, Blennow, Kaj, Pomara, Nunzio

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Association of Apolipoprotein E ε4 Allele With Clinical and Multimodal Biomarker Changes of Alzheimer Disease in Adults With Down Syndrome von Bejanin, Alexandre, Florencia Iulita, Maria, Vilaplana, Eduard, Carmona-Iragui, Maria, Benejam, Bessy, Videla, Laura, Barroeta, Isabel, Fernandez, Susana, Altuna, Miren, Pegueroles, Jordi, Montal, Victor, Valldeneu, Silvia, Gimenez, Sandra, Gonzalez-Ortiz, Sofia, Munoz, Laia, Padilla, Concepcion, Rozalem Aranha, Mateus, Estelles, Teresa, Illan-Gala, Ignacio, Belbin, Olivia, Camacho, Valle, Wilson, Liam Reese, Annus, Tiina, Osorio, Ricardo S., Videla, Sebastian, Lehmann, Sylvain, Holland, Anthony J., Zetterberg, Henrik, Blennow, Kaj, Alcolea, Daniel, Clarimon, Jordi, Zaman, Shahid H., Blesa, Rafael, Lleo, Alberto, Fortea, Juan

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Plasma Amyloid-β dynamics in late-life major depression: a longitudinal study von Pomara, Nunzio, Bruno, Davide, Plaska, Chelsea Reichert, Ramos-Cejudo, Jaime, Osorio, Ricardo S., Pillai, Anilkumar, Imbimbo, Bruno P., Zetterberg, Henrik, Blennow, Kaj

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Sleep oscillation-specific associations with Alzheimer's disease CSF biomarkers: novel roles for sleep spindles and tau von Kam, Korey, Parekh, Ankit, Sharma, Ram A, Andrade, Andreia, Lewin, Monica, Castillo, Bresne, Bubu, Omonigho M, Chua, Nicholas J, Miller, Margo D, Mullins, Anna E, Glodzik, Lidia, Mosconi, Lisa, Gosselin, Nadia, Prathamesh, Kulkarni, Chen, Zhe, Blennow, Kaj, Zetterberg, Henrik, Bagchi, Nisha, Cavedoni, Bianca, Rapoport, David M, Ayappa, Indu, de Leon, Mony J, Petkova, Eva, Varga, Andrew W, Osorio, Ricardo S

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0864 Race/ethnicity And Sex-dependent Effects Of Metabolic Burden Across Different Age-categories On Trends In Self-reported Sleep Duration: Findings From The National Health Inter... von Eirene, O, Bubu, O M, Donley, T, Blanc, J, Madera, C, Turner, A, Mbah, A K, Williams, N J, Youngstedt, S, Shochat, T, Seixas, A A, Osorio, R S, Jean-Louis, G

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0863 Age-categorized Trends In Self-reported Sleep Duration For The Non-institutionalized U.s. Civilian Population From 2004-2013: Considerations Of Racial/ethnic Variations von Christina, M, Bubu, O M, Donley, T, Blanc, J, Oji, E, Turner, A D, Mbah, A K, Williams, N J, Youngstedt, S, Shochat, T, Azizi, S A, Osorio, R S, Jean-Louis, G

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1150 Obstructive Sleep Apnea-dependent Racial/ethnic And Sex-specific Mechanisms Underlying Alzheimer’s Disease Risk: A Retrospective Cohort Analysis Of In-lab PSG Sleep Study Data... von Bubu, O M, Turner, A D, Parekh, A, Mullins, A, Kam, K, Umasabor-Bubu, O Q, Mbah, A K, Williams, N J, Varga, A W, Rapoport, D M, Ayappa, I, Jean-Louis, G, Osorio, R S

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1153 Association Of Nocturnal Sleep Disturbance And Prospective Cognitive Decline In Cognitive Normal Elderly: Findings From The National Alzheimer’s Coordinating Center Uniform Da... von Bubu, O M, Mbah, A K, Williams, N J, Turner, A D, Parekh, A, Mullins, A E, Kam, K, Umasabor-Bubu, O Q, Varga, A W, Rapoport, D M, Ayappa, I, Jean-Louis, G, Osorio, R S

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0292 Sleep Spindle Characteristics and Their Association with Cerebrospinal Fluid Biomarkers of Alzheimer’s Disease in Cognitively Normal Older Adults von Varga, A W, Kam, K, Parekh, A, Sharma, R A, Castillo, B, Miller, M D, Bagchi, N, Rapoport, D M, Ayappa, I, Osorio, R S

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0970 Sleep Spindle Count In Subsyndromal Depressed vs Normal Elderly: A Protective Effect Of Sleep Spindles? von Sharma, R A, Miller, M D, Kam, K, Parekh, A, Rivas, J, Bubu, O M, Varga, A W, Iosifescu, D V, Osorio, R S

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0695 Objectively Measured Total Sleep Time as a Tool to Detect Longitudinal Changes In Alzheimer’s Disease Neuroimaging Biomarker (FDG PET) von Sharma, R A, Miller, M D, Kam, K, Parekh, A, Bubu, O M, Rivas, J, Ayappa, I, Rapoport, D M, Varga, A W, Osorio, R S

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0143 Associations Between Slow Wave Sleep Duration, Insulin Resistance, and Respiratory Effort-Related Arousals in Young Adults von Rivas, J, Sharma, R, Miller, M D, Godinho, A, Ayappa, I, Jean-Louis, G, Varga, A W, Convit, A, Osorio, R S

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