Evaluation of Sofosbuvir (β-D-2′-deoxy-2′-α-fluoro-2′-β-C-methyluridine) as an inhibitor of Dengue virus replication von Xu, Hong-Tao, Colby-Germinario, Susan P., Hassounah, Said A., Fogarty, Clare, Osman, Nathan, Palanisamy, Navaneethan, Han, Yingshan, Oliveira, Maureen, Quan, Yudong, Wainberg, Mark A.

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Differential effects of the G118R, H51Y, and E138K resistance substitutions in different subtypes of HIV integrase von Quashie, Peter K, Oliviera, Maureen, Veres, Tamar, Osman, Nathan, Han, Ying-Shan, Hassounah, Said, Lie, Yolanda, Huang, Wei, Mesplède, Thibault, Wainberg, Mark A

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Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase von QUASHIE, Peter K, MESPLEDE, Thibault, HAN, Ying-Shan, VERES, Tamar, OSMAN, Nathan, HASSOUNAH, Said, SLOAN, Richard D, XU, Hong-Tao, WAINBERG, Mark A

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The Role of Phylogenetics in Unravelling Patterns of HIV Transmission towards Epidemic Control: The Quebec Experience (2002-2020) von Brenner, Bluma G., Ibanescu, Ruxandra-Ilinca, Osman, Nathan, Cuadra-Foy, Ernesto, Oliveira, Maureen, Chaillon, Antoine, Stephens, David, Hardy, Isabelle, Routy, Jean-Pierre, Thomas, Rejean, Baril, Jean-Guy, Leblanc, Roger, Tremblay, Cecile, Roger, Michel

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Selection of the R263K and H51Y resistance substitutions for DTG causes diminished integration and explains the lack of clinically significant drug resistance to this compound von Mesplède, Thibault, Liang, Jiaming, Anstett, Katlin, Osman, Nathan, Thi Pham, Hanh, Wainberg, Mark A.

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Long Dissociation of Bictegravir from HIV-1 Integrase-DNA Complexes von White, Kirsten L., Osman, Nathan, Cuadra-Foy, Ernesto, Brenner, Bluma G., Shivakumar, Devleena, Campigotto, Federico, Tsiang, Manuel, Morganelli, Philip A., Novikov, Nikolai, Lazerwith, Scott E., Jin, Haolun, Niedziela-Majka, Anita

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Antiviral Activity of Bictegravir and Cabotegravir against Integrase Inhibitor-Resistant SIVmac239 and HIV-1 von Hassounah, Said A, Alikhani, Ahmad, Oliveira, Maureen, Bharaj, Simrat, Ibanescu, Ruxandra-Ilinca, Osman, Nathan, Xu, Hong-Tao, Brenner, Bluma G, Mesplède, Thibault, Wainberg, Mark A

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The M50I polymorphic substitution in association with the R263K mutation in HIV-1 subtype B integrase increases drug resistance but does not restore viral replicative fitness von Wares, Melissa, Mesplède, Thibault, Quashie, Peter K, Osman, Nathan, Han, Yingshan, Wainberg, Mark A

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380. INTEGRATIVE TRANSCRIPTOMIC AND FUNCTIONAL ANALYSIS OF CHEMOTHERAPY RESISTANCE IN ESOPHAGEAL ADENOCARCINOMA von Kong, Mingyang (Iris), Pal, Sanjima, Qian, Qiu, Tai, Kulsum, Osman, Nathan, Berube, Julie, Bourdeau, France, Zeng, Wotan, Giannias, Betty, Huang, Sui, Bailey, Swneke, Sangwan, Veena, Bertos, Nick, Ferri, Lorenzo

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Addition of E138K to R263K in HIV integrase increases resistance to dolutegravir, but fails to restore activity of the HIV integrase enzyme and viral replication capacity von Mesplède, Thibault, Osman, Nathan, Wares, Melissa, Quashie, Peter K, Hassounah, Said, Anstett, Kaitlin, Han, Yingshan, Singhroy, Diane N, Wainberg, Mark A

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Viral fitness cost prevents HIV-1 from evading dolutegravir drug pressure von Mesplède, Thibault, Quashie, Peter K, Osman, Nathan, Han, Yingshan, Singhroy, Diane N, Lie, Yolanda, Petropoulos, Christos J, Huang, Wei, Wainberg, Mark A

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Durable suppression of HIV-1 with resistance mutations to integrase inhibitors by dolutegravir following drug washout von Osman, Nathan, Mesplède, Thibault, Oliveira, Maureen, Hassounah, Said, Wainberg, Mark A, Brenner, Bluma G

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Dolutegravir maintains a durable effect against HIV replication in tissue culture even after drug washout von Osman, Nathan, Mesplède, Thibault, Quashie, Peter K, Oliveira, Maureen, Zanichelli, Veronica, Wainberg, Mark A

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The R263K substitution in HIV-1 subtype C is more deleterious for integrase enzymatic function and viral replication than in subtype B von Mesplède, Thibault, Quashie, Peter K, Hassounah, Said, Osman, Nathan, Han, Yingshan, Liang, Jiaming, Singhroy, Diane N, Wainberg, Mark A

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Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase von Quashie, Peter K, Mesplède, Thibault, Han, Ying-Shan, Veres, Tamar, Osman, Nathan, Hassounah, Said, Sloan, Richard D, Xu, Hong-Tao, Wainberg, Mark A

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Does antiretroviral treatment change HIV-1 codon usage patterns in its genes: a preliminary bioinformatics study von Palanisamy, Navaneethan, Osman, Nathan, Ohnona, Frédéric, Xu, Hong-Tao, Brenner, Bluma, Mesplède, Thibault, Wainberg, Mark A

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Biochemical Analysis of the Role of G118R-Linked Dolutegravir Drug Resistance Substitutions in HIV-1 Integrase von Quashie, Peter K, Mesplède, Thibault, Han, Ying-Shan, Veres, Tamar, Osman, Nathan, Hassounah, Said, Sloan, Richard D, Xu, Hong-Tao, Wainberg, Mark A

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New insights into estrogenic regulation of O~6-methylguanine DNA-methyltransferase(MGMT) in human breast cancer cells:Co-degradation of ER-α and MGMT proteins by fulvestrant or O~6... von Paranjpe, Ameya, Bailey, Nathan I, Konduri, Santhi, Bobustuc, George C, Ali-Osman, Francis, Yusuf, Mohd A, Punganuru, Surendra R, Madala, Hanumantha Rao, Basak, Debasish, Mostofa, Agm, Srivenugopal, Kalkunte S

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DNA methylation among firefighters von Zhou, Jin, Jenkins, Timothy G, Jung, Alesia M, Jeong, Kyoung Sook, Zhai, Jing, Jacobs, Elizabeth T, Griffin, Stephanie C, Dearmon-Moore, Devi, Littau, Sally R, Peate, Wayne F, Ellis, Nathan A, Lance, Peter, Chen, Yin, Burgess, Jefferey L

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Exploring the photocatalytic hydrogen production potential of titania doped with alumina derived from foil waste von Osman, Ahmed I., Skillen, Nathan C., Robertson, Peter K.J., Rooney, David W., Morgan, Kevin

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