Masitinib decreases signs of canine atopic dermatitis: a multicentre, randomized, double-blind, placebo-controlled phase 3 trial von Cadot, Pierre, Hensel, Patrick, Bensignor, Emmanuel, Hadjaje, Céline, Marignac, Geneviève, Beco, Luc, Fontaine, Jacques, Jamet, Jean-François, Georgescu, Gabriela, Campbell, Karen, Cannon, Andréa, Osborn, Sarah C., Messinger, Linda, Gogny-Goubert, Michel, Dubreuil, Patrice, Moussy, Alain, Hermine, Olivier

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Base Editor Correction of COL7A1 in Recessive Dystrophic Epidermolysis Bullosa Patient-Derived Fibroblasts and iPSCs von Osborn, Mark J., Newby, Gregory A., McElroy, Amber N., Knipping, Friederike, Nielsen, Sarah C., Riddle, Megan J., Xia, Lily, Chen, Weili, Eide, Cindy R., Webber, Beau R., Wandall, Hans H., Dabelsteen, Sally, Blazar, Bruce R., Liu, David R., Tolar, Jakub

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Comparison of partially and fully chemically-modified siRNA in conjugate-mediated delivery in vivo von Hassler, Matthew R, Turanov, Anton A, Alterman, Julia F, Haraszti, Reka A, Coles, Andrew H, Osborn, Maire F, Echeverria, Dimas, Nikan, Mehran, Salomon, William E, Roux, Loïc, Godinho, Bruno M D C, Davis, Sarah M, Morrissey, David V, Zamore, Phillip D, Karumanchi, S Ananth, Moore, Melissa J, Aronin, Neil, Khvorova, Anastasia

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Hydrophobicity drives the systemic distribution of lipid-conjugated siRNAs via lipid transport pathways von Osborn, Maire F, Coles, Andrew H, Biscans, Annabelle, Haraszti, Reka A, Roux, Loic, Davis, Sarah, Ly, Socheata, Echeverria, Dimas, Hassler, Matthew R, Godinho, Bruno M D C, Nikan, Mehran, Khvorova, Anastasia

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Evaluation of TCR Gene Editing Achieved by TALENs, CRISPR/Cas9, and megaTAL Nucleases von Osborn, Mark J, Webber, Beau R, Knipping, Friederike, Lonetree, Cara-lin, Tennis, Nicole, DeFeo, Anthony P, McElroy, Amber N, Starker, Colby G, Lee, Catherine, Merkel, Sarah, Lund, Troy C, Kelly-Spratt, Karen S, Jensen, Michael C, Voytas, Daniel F, von Kalle, Christof, Schmidt, Manfred, Gabriel, Richard, Hippen, Keli L, Miller, Jeffrey S, Scharenberg, Andrew M, Tolar, Jakub, Blazar, Bruce R

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Prescribing of antipsychotics for people diagnosed with severe mental illness in UK primary care 2000-2019: 20-year investigation of who receives treatment, with which agents and a... von Richards-Belle, Alvin, Launders, Naomi, Hardoon, Sarah, Man, Kenneth K C, Bramon, Elvira, Osborn, David P J, Hayes, Joseph F

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Protocolised Management In Sepsis (ProMISe): a multicentre randomised controlled trial of the clinical effectiveness and cost-effectiveness of early, goal-directed, protocolised re... von Mouncey, Paul R, Osborn, Tiffany M, Power, G Sarah, Harrison, David A, Sadique, M Zia, Grieve, Richard D, Jahan, Rahi, Tan, Jermaine C K, Harvey, Sheila E, Bell, Derek, Bion, Julian F, Coats, Timothy J, Singer, Mervyn, Young, J Duncan, Rowan, Kathryn M

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Six-Month Randomized, Multicenter Trial of Closed-Loop Control in Type 1 Diabetes von Brown, Sue A, Kovatchev, Boris P, Raghinaru, Dan, Lum, John W, Buckingham, Bruce A, Kudva, Yogish C, Laffel, Lori M, Levy, Carol J, Pinsker, Jordan E, Wadwa, R. Paul, Dassau, Eyal, Doyle, Francis J, Anderson, Stacey M, Church, Mei Mei, Dadlani, Vikash, Ekhlaspour, Laya, Forlenza, Gregory P, Isganaitis, Elvira, Lam, David W, Kollman, Craig, Beck, Roy W

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Delayed versus Immediate Cord Clamping in Preterm Infants von Tarnow-Mordi, William, Morris, Jonathan, Kirby, Adrienne, Robledo, Kristy, Askie, Lisa, Brown, Rebecca, Evans, Nicholas, Finlayson, Sarah, Fogarty, Michael, Gebski, Val, Ghadge, Alpana, Hague, Wendy, Isaacs, David, Jeffery, Michelle, Keech, Anthony, Kluckow, Martin, Popat, Himanshu, Sebastian, Lucille, Aagaard, Kjersti, Belfort, Michael, Pammi, Mohan, Abdel-Latif, Mohamed, Reynolds, Graham, Ariff, Shabina, Sheikh, Lumaan, Chen, Yan, Colditz, Paul, Liley, Helen, Pritchard, Margo, de Luca, Daniele, de Waal, Koert, Forder, Peta, Duley, Lelia, El-Naggar, Walid, Gill, Andrew, Newnham, John, Simmer, Karen, Groom, Katie, Weston, Philip, Gullam, Joanna, Patel, Harshad, Koh, Guan, Lui, Kei, Marlow, Neil, Morris, Scott, Sehgal, Arvind, Wallace, Euan, Soll, Roger, Young, Leslie, Sweet, David, Walker, Susan, Watkins, Andrew, Wright, Ian, Osborn, David, Simes, John

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Incidence of mental health diagnoses during the COVID-19 pandemic: a multinational network study von Chai, Yi, Man, Kenneth K. C., Luo, Hao, Torre, Carmen Olga, Wing, Yun Kwok, Hayes, Joseph F., Osborn, David P. J., Chang, Wing Chung, Lin, Xiaoyu, Yin, Can, Chan, Esther W., Lam, Ivan C. H., Fortin, Stephen, Kern, David M., Lee, Dong Yun, Park, Rae Woong, Jang, Jae-Won, Li, Jing, Seager, Sarah, Lau, Wallis C. Y., Wong, Ian C. K.

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Safety and immunogenicity of the ChAdOx1 nCoV-19 vaccine against SARS-CoV-2: a preliminary report of a phase 1/2, single-blind, randomised controlled trial von Aley, Parvinder K, Clutterbuck, Elizabeth A, Dold, Christina, Heath, Paul, Makinson, Rebecca, Pollock, Katrina M, Ramasamy, Maheshi, Robinson, Hannah, Douglas, Alexander D, Lambe, Teresa, Aboagye, Jeremy, Allen, Elizabeth, Anslow, Rachel, Baker, Philip, Bates, Louise, Batten, Alexander, Berry, Lisa, Beveridge, Amy, Bingham, Tracey, Brunt, Emily, Burbage, Jamie, Carroll, Miles W., Coombes, Naomi S., Cooper, Rachel, Crocker, Wendy E.M., Di Maso, Claudio, Dong, Tao, Douglas, Naomi, Downing, Charlotte, Elias, Sean C., Emary, Katherine R.W., Fletcher, Clare, Ford, Karen J., Fox, Polly, Frater, John, Galiza, Eva, Godwin, Kerry, Gorini, Giacomo, Goulston, Lyndsey, Gracie, Lara, Halwe, Sandro, Hamilton, Elizabeth, Hamlyn, Joseph, Harding, Irasha, Head, Ian, Hodgson, Susanne H.C., Howell, Nicola, Isitt, Catherine, Kailath, Reshma, Karampatsas, Konstantinos, Kerridge, Simon, Khan, Uzma, Kingham-Page, Lucy, Knott, Daniel, Koleva, Stanislava, Kupke, Alexandra, Lawrie, Alison M., Lee, Arlene, Lees, Emily A, Lias, Amelia M., Linder, Aline, Lopez Ramon, Raquel, Marlow, Emma, Marshall, Julia L., Meddaugh, Gretchen, Moore, Maria, Moran, Edward, Morris, Susan Jane, Morshead, Gertraud, Muller, Jilly, Munro, Alasdair, Noé, Andrés, O'Brien, Katie, O'Connor, Daniel, Oguti, Blanché, Oliver, Jennifer L., Osborn, Mairead, Pacurar, Mihaela, Pearce, Jennifer, Pfafferott, Katja, Poulton, Ian, Riddell, Amy, Sajjad, Sara, Sanders, Helen, Sanders, Katherine, Selby, Beatrice, Shelton, Holly, Song, Rinn, Stefanova, Elena, Tait, Moira, Talbot, Helen, Themistocleous, Yrene, Thomas, Merin, Towner, James, Turkentine, Kate, Turner, Sally, Veighey, Kristin, Vichos, Iason, Worth, Andrew T., Yau, Yasmine

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Fibrinogen Fragment X Mediates Endothelial Barrier Disruption via Suppression of VE-Cadherin von Olson, Sarah A., Osborn, Baron K., Cotton, Madeline E., Krocker, Joseph D., Koami, Hiroyuki, White, Nathan, Cardenas, Jessica C.

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Engineered virus-like particles for efficient in vivo delivery of therapeutic proteins von Banskota, Samagya, Raguram, Aditya, Suh, Susie, Du, Samuel W., Davis, Jessie R., Choi, Elliot H., Wang, Xiao, Nielsen, Sarah C., Newby, Gregory A., Randolph, Peyton B., Osborn, Mark J., Musunuru, Kiran, Palczewski, Krzysztof, Liu, David R.

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Community prevalence of SARS-CoV-2 in England from April to November, 2020: results from the ONS Coronavirus Infection Survey von Pouwels, Koen B, House, Thomas, Pritchard, Emma, Robotham, Julie V, Birrell, Paul J, Gelman, Andrew, Vihta, Karina-Doris, Bowers, Nikola, Boreham, Ian, Thomas, Heledd, Bell, Iain, Bell, John I, Newton, John N, Farrar, Jeremy, Benton, Pete, Walker, Ann Sarah, Pouwels, Koen B., Crook, Derrick, Matthews, Philippa C., Peto, Tim, Pritchard, Emma, Stoesser, Nicole, Vihta, Karina-Doris, Howarth, Alison, Doherty, George, Kavanagh, James, Chau, Kevin K., Martins Ferreira, Lucas, Marsden, Brian D., Mongkolsapaya, Juthathip, Cornall, Richard, Stuart, David I., Screaton, Gavin, Bell, John, Cox, Stuart, Paddon, Kevin, James, Tim, House, Thomas, Newton, John N., Birrell, Paul, Sheppard, Tim, Athey, Graham, Moody, Dan, Curry, Leigh, Brereton, Pamela, Hay, Jodie, Vansteenhouse, Harper, Benton, Pete, Rourke, Emma, Henry, Sarah, Scruton, James, Stokes, Peter, Thomas, Tina, Allen, John, Black, Russell, Bovill, Heather, Braunholtz, David, Brown, Dominic, Collyer, Sarah, Crees, Megan, Daglish, Colin, Davies, Byron, Donnarumma, Hannah, Douglas-Mann, Julia, Felton, Antonio, Finselbach, Hannah, Fordham, Eleanor, Ipser, Alberta, Jenkins, Joe, Kent, Katherine, Kerai, Geeta, Lloyd, Lina, Masding, Victoria, Osborn, Ellie, Patel, Alpi, Pereira, Elizabeth, Pett, Tristan, Reeve, Donna, Shah, Palvi, Snook, Ruth, Studley, Ruth, Sutherland, Esther, Swinn, Eliza, Thomas, Heledd, Tudor, Anna, Weston, Joshua, Leib, Shayla, Tierney, James, Farkas, Gabor, Cobb, Raf, Compton, Lewis, Irving, James, Clarke, John, Mullis, Rachel, Ireland, Lorraine, Airimitoaie, Diana, Fisher, Sarah, Moore, Zoe, McLean, James, Kerby, Matt

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Epigenetic tuning of PD-1 expression improves exhausted T cell function and viral control von Weiss, Sarah A., Huang, Amy Y., Fung, Megan E., Martinez, Daniela, Chen, Alex C. Y., LaSalle, Thomas J., Miller, Brian C., Scharer, Christopher D., Hegde, Mudra, Nguyen, Thao H., Rowe, Jared H., Osborn, Jossef F., Patterson, Dillon G., Sifnugel, Natalia, Mei-An Nolan, C., Davidson, Richard A., Schwartz, Marc A., Bally, Alexander P. R., Neeld, Dennis K., LaFleur, Martin W., Boss, Jeremy M., Doench, John G., Nicholas Haining, W., Sharpe, Arlene H., Sen, Debattama R.

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Understanding Young Adults’ Reports of Contact with their Parents in a Digital World: Psychological and Familial Relationship Factors von Stein, Catherine H., Osborn, Lawrence A., Greenberg, Sarah C.

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Disruption of HIV-1 co-receptors CCR5 and CXCR4 in primary human T cells and hematopoietic stem and progenitor cells using base editing von Knipping, Friederike, Newby, Gregory A., Eide, Cindy R., McElroy, Amber N., Nielsen, Sarah C., Smith, Kyle, Fang, Yongxing, Cornu, Tatjana I., Costa, Caroline, Gutierrez-Guerrero, Alejandra, Bingea, Samuel P., Feser, Colby J., Steinbeck, Benjamin, Hippen, Keli L., Blazar, Bruce R., McCaffrey, Anton, Mussolino, Claudio, Verhoeyen, Els, Tolar, Jakub, Liu, David R., Osborn, Mark J.

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Randomized Controlled Trial of Mobile Closed-Loop Control von Kovatchev, Boris, Anderson, Stacey M, Raghinaru, Dan, Kudva, Yogish C, Laffel, Lori M, Levy, Carol, Pinsker, Jordan E, Wadwa, R Paul, Buckingham, Bruce, Doyle, 3rd, Francis J, Brown, Sue A, Church, Mei Mei, Dadlani, Vikash, Dassau, Eyal, Ekhlaspour, Laya, Forlenza, Gregory P, Isganaitis, Elvira, Lam, David W, Lum, John, Beck, Roy W

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CRISPR/Cas9-Based Cellular Engineering for Targeted Gene Overexpression von Osborn, Mark J, Lees, Christopher J, McElroy, Amber N, Merkel, Sarah C, Eide, Cindy R, Mathews, Wendy, Feser, Colby J, Tschann, Madison, McElmury, Ron T, Webber, Beau R, Kim, Chong Jai, Blazar, Bruce R, Tolar, Jakub

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A Randomized Clinical Trial Assessing Continuous Glucose Monitoring (CGM) Use With Standardized Education With or Without a Family Behavioral Intervention Compared With Fingerstick... von Laffel, Lori, Harrington, Kara, Hanono, Anat, Naik, Nisha, Ambler-Osborn, Louise, Schultz, Alan, DiMeglio, Linda, Woerne, Stephanie, Jolivette, Heather, Ismail, Heba, Tebbe, Megan, Newman, America, Legge, Megan, Tamborlane, William, Van Name, Michelle, Weyman, Kate, Finnegan, Jennifer, Steffen, Amy, Zgorski, Melinda, DeSalvo, Daniel, Hilliard, Marisa, DeLaO, Kylie, Xie, Cicilyn, Levy, Wendy, Wadwa, R. Paul, Forlenza, Greg, Majidi, Shideh, Alonso, Guy, Weber, Isabel, Clay, Michelle, Simmons, Emily, Nathan, Brandon, Sunni, Muna, Sweet, Jessica, Pappenfus, Beth, Kogler, Anne, Ludwig, Marrissa, Nelson, Brittney, Street, Anne, Weingartner, Darcy, Albanese-O’Neill, Anastasia, Haller, Michael, Adams, Janey, Cintron, Miriam, Thomas, Nicole, Kelley, Jennifer, Simmons, Jill, William, George, Brendle, Faith, Goland, Robin, Williams, Kristen, Gandica, Rachelle, Pollak, Sarah, Casciano, Emily, Robinson, Elizabeth, Willi, Steven, Minnock, Pantea, Olivos, Diana, Carchidi, Cathy, Grant, Brian, Wong, Jenise C., Adi, Saleh, Corathers, Sarah, Sheanon, Nicole, Fox, Cathy, Weis, Tammy, MacLeish, Sarah, Wood, Jamie, Casey, Terri, Campbell, Wendy, McGuigan, Paul, Wintergerst, Kupper, Watson, Sara, Kingery, Suzanne, Pierce, Gwen, Ruch, Heather, Rayborn, Lauren, Rodriguez-Luna, Manuel, Deuser, Amy

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