P850: THE EFFECT OF UROLITHIN PRODUCTION BY GUT MICROBIOTA IN MULTIPLE MYELOMA von Rodríguez‐García, Alba, Garcia‐Vicente, Roberto, Ancos, Raquel, Ortiz‐Ruiz, Alejandra, Ángel Navarro, Miguel, Arroyo, Andrés, Fernández, María Luz Morales, Guevara‐Ramirez, Patricia, Justo, Pablo, Selma, Victoria, Tomás‐Barberán, Francisco A., Ayala Diaz, Rosa, Martinez‐Lopez, Joaquín, Linares, María

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S179: HNRNPK OVEREXPRESSION DRIVES NUCLEOLAR ABERRANCIES CAUSING RIBOSOMPATHIES von Garrido, Pedro Aguilar, Estevez, Maria Velasco, Ángel Navarro Aguadero, Miguel, Hernández Sánchez, María, Malaney, Prerna, Hornbaker, Marisa, Zhang, Xiaorui, Ibañez Navarro, Marta, Ortiz‐Ruiz, Alejandra, Otero‐Sobrino, Álvaro, Megías, Diego, Pérez, Manuel, Gómez, Jesús, Mata, Gadea, Dominguez, Orlando, Grana, Osvaldo, Caleiras, Eduardo, Isasa, Marta, Andrés, Paloma Jimena, Rodriguez, Sandra, Torres, Raúl, Sirozh, Oleksandra, Lafarga, Vanesa, Martínez‐Lopez, Joaquín, Post, Sean, Gallardo, Miguel

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Protein Carbonylation and Lipid Peroxidation in Hematological Malignancies von Rodríguez-García, Alba, García-Vicente, Roberto, Morales, María Luz, Ortiz-Ruiz, Alejandra, Martínez-López, Joaquín, Linares, María

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Droplet Microfluidics for the ex Vivo Expansion of Human Primary Multiple Myeloma Cells von Carreras, Pilar, Gonzalez, Iciar, Gallardo, Miguel, Ortiz-Ruiz, Alejandra, Martinez-Lopez, Joaquin

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Plasmodium species differentiation by non-expert on-line volunteers for remote malaria field diagnosis von Ortiz-Ruiz, Alejandra, Postigo, María, Gil-Casanova, Sara, Cuadrado, Daniel, Bautista, José M, Rubio, José Miguel, Luengo-Oroz, Miguel, Linares, María

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Long-Term Human Hematopoietic Stem Cell Culture in Microdroplets von Carreras, Pilar, González, Itziar, Gallardo, Miguel, Ortiz-Ruiz, Alejandra, Morales, Maria Luz, Encinas, Jessica, Martínez-López, Joaquín

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Myc-Related Mitochondrial Activity as a Novel Target for Multiple Myeloma von Ortiz-Ruiz, Alejandra, Ruiz-Heredia, Yanira, Morales, María Luz, Aguilar-Garrido, Pedro, García-Ortiz, Almudena, Valeri, Antonio, Bárcena, Carmen, García-Martin, Rosa María, Garrido, Vanesa, Moreno, Laura, Gimenez, Alicia, Navarro-Aguadero, Miguel Ángel, Velasco-Estevez, María, Lospitao, Eva, Cedena, María Teresa, Barrio, Santiago, Martínez-López, Joaquín, Linares, María, Gallardo, Miguel

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Collaborative intelligence and gamification for on-line malaria species differentiation von Linares, María, Postigo, María, Cuadrado, Daniel, Ortiz-Ruiz, Alejandra, Gil-Casanova, Sara, Vladimirov, Alexander, García-Villena, Jaime, Nuñez-Escobedo, José María, Martínez-López, Joaquín, Rubio, José Miguel, Ledesma-Carbayo, María Jesús, Santos, Andrés, Bassat, Quique, Luengo-Oroz, Miguel

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Posttranslational splicing modifications as a key mechanism in cytarabine resistance in acute myeloid leukemia von Morales, María Luz, García-Vicente, Roberto, Rodríguez-García, Alba, Reyes-Palomares, Armando, Vincelle-Nieto, África, Álvarez, Noemí, Ortiz-Ruiz, Alejandra, Garrido-García, Vanesa, Giménez, Alicia, Carreño-Tarragona, Gonzalo, Sánchez, Ricardo, Ayala, Rosa, Martínez-López, Joaquín, Linares, María

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Study of the Role of Splicing Factor SRRM2 in Cytarabine Treatment Resistance in Acute Myeloid Leukemia von Morales, María Luz, Garcia-Vicente, Roberto, Álvarez Sánchez-Redondo, Noemí, Rodríguez García, Alba, Ortiz-Ruiz, Alejandra, Reyes-Palomares, Armando, Hermouet, Sylvie, Ayala, Rosa, Martinez-Lopez, Joaquin, Linares, María

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MEK inhibition enhances the response to tyrosine kinase inhibitors in acute myeloid leukemia von Morales, María Luz, Arenas, Alicia, Ortiz-Ruiz, Alejandra, Leivas, Alejandra, Rapado, Inmaculada, Rodríguez-García, Alba, Castro, Nerea, Zagorac, Ivana, Quintela-Fandino, Miguel, Gómez-López, Gonzalo, Gallardo, Miguel, Ayala, Rosa, Linares, María, Martínez-López, Joaquín

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The Spliceosome As a New Therapeutic Target in Cytarabine-Resistant Acute Myeloid Leukemia von Morales, María Luz, Garcia-Vicente, Roberto, Rodríguez García, Alba, Álvarez Sánchez-Redondo, Noemí, Ortiz-Ruiz, Alejandra, Reyes-Palomares, Armando, Sanchez, Ricardo, Garrido-Garcia, Vanesa, Carreño-Tarragona, Gonzalo, Hermouet, Sylvie, Ayala, Rosa, Martinez Lopez, Joaquin, Linares, María

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Hnrnpk Overexpression Drives Nucleolar Aberrancies Causing Ribosomopathies von Aguilar-Garrido, Pedro, Velasco-Estevez, Maria, Navarro-Aguadero, Miguel Ángel, Hernández-Sánchez, María, Ibáñez-Navarro, Marta, Malaney, Prerna, Aitken, Marisa, Zhang, Xiaorui, Fernández, Adrián, Ortiz-Ruiz, Alejandra, Otero-Sobrino, Álvaro, Megías, Diego, Pérez, Manuel, Gómez, Jesús, Mata, Gadea, Domínguez, Orlando, Graña, Osvaldo, Ximénez, Pilar, Isasa, Marta, Jimena-de Andrés, Paloma, Rodríguez, Sandra, Torres, Raúl, Lafarga, Miguel, Sirozh, Oleksandra, Lafarga, Vanesa, Martinez-Lopez, Joaquin, Post, Sean M., Gallardo, Miguel

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The Augmented Hematologist: Human-AI Feedback Loops to Assist Differential Cell Count during the Analysis of Bone Marrow Aspirates von Bermejo-Peláez, David, Rueda Charro, Sandra, Mousa, Adriana, Alamo, Elisa, Garcia Roa, Maria, Trelles-Martínez, Roberto, Hidalgo Soto, Marta, Bobes-Fernández, Alejandro, Garcia-Vicente, Roberto, Morales, María Luz, Rodríguez García, Alba, Ortiz-Ruiz, Alejandra, Blanco-Sánchez, Alberto, Lin, Lin, Dacal, Elena, Ayala, Rosa, Luengo-Oroz, Miguel, Linares, María, Martinez Lopez, Joaquin

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P-212 The effect of urolithin production by gut microbiota in multiple myeloma von Rodriguez-Garcia, Alba, Garcia-Vicente, Roberto, Ancos, Raquel, Ortiz-Ruiz, Alejandra, Arroyo, Andrés, Morales, María Luz, Navarro, Miguel Ángel, Guevara-Ramirez, Patricia, Justo, Pablo, Selma, Victoria, Tomas-Barberan, Francisco, Ayala, Rosa, Martinez-Lopez, Joaquín, Linares, María

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P-199 Artificial Intelligence System To Predict t(11,14) Status in Multiple Myeloma Patients by Leveraging the Correlation of Plasma Cell Morphology and Genetics von Bermejo-Peláez, David, Mendoza, Ana, Rodríguez, Sandra, Díez, Nuria, Brau-Queralt, David, Postigo, María, Gómez, Miguel, Hidalgo, Marta, Oños, Adriana, Rodríguez-Garcia, Alba, Ortiz-Ruiz, Alejandra, Garcia-Vicente, Roberto, Ancos-Pintado, Raquel, Caballero, Carla, Angulo, Alejandro, Vladimirov, Alexander, Colmenares, Rafael, Jesús Ledesma-Carbayo, María, Linares, María, Montoro, María Julia, Benavente, Celina, Martínez-Lopez, Joaquín

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Increase of Mitochondrial Activity Contributes to the Bortezomib-Relapsed in Multiple Myeloma, a Novel Therapeutic Opportunity von Ortiz-Ruiz, Alejandra, Ruiz-Heredia, Yanira, Samur, Mehmet, Aguilar-Garrido, Pedro, Morales, Maria Luz, Valeri, Antonio, Garcia-Ortiz, Almudena, Barrio, Santiago, Bárcena, Carmen, Garcia-Martin, Rosa Maria, Garrido, Vanesa, Fulciniti, Mariateresa, Munshi, Nikhil C., Cedena, María Teresa, Martinez-Lopez, Joaquin, Linares, Maria, Gallardo, Miguel

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Pathogenetic and Prognostic Implications of Increased Mitochondrial Content in Multiple Myeloma von Ruiz-Heredia, Yanira, Ortiz-Ruiz, Alejandra, Samur, Mehmet K, Garrido, Vanesa, Rufian, Laura, Sanchez, Ricardo, Aguilar-Garrido, Pedro, Barrio, Santiago, Martín, Miguel A, Bolli, Niccolò, Tai, Yu-Tzu, Szalat, Raphaël, Fulciniti, Mariateresa, Munshi, Nikhil, Martínez-López, Joaquín, Linares, María, Gallardo, Miguel

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Abnormalities in Mitochondrial DNA Copy Number Have Pathogenetic and Prognostic Implications in Multiple Myeloma von Ruiz-Heredia, Yanira, Samur, Mehmet Kemal, Ortiz-Ruiz, Alejandra, Fernández, Rafael Alonso, Sanchez-Vega, Beatriz, Blazquez, Alberto, Delmiro, Aitor, Martinez-Avila, Jose Carlos, Onecha, Esther, Valeri, Antonio, Martin, Miguel Angel, Bolli, Niccolo, Tai, Yu-Tzu, Maura, Francesco, Szalat, Raphael, Fulciniti, Mariateresa, Linares, María, Gallardo, Miguel, Campbell, Peter J, Avet-Loiseau, Hervé, Lahuerta, Juan Jose, Munshi, Nikhil, Martinez-Lopez, Joaquin

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Impaired FADD/BID signaling mediates cross-resistance to immunotherapy in Multiple Myeloma von Munawar, Umair, Zhou, Xiang, Prommersberger, Sabrina, Nerreter, Silvia, Vogt, Cornelia, Steinhardt, Maximilian J., Truger, Marietta, Mersi, Julia, Teufel, Eva, Han, Seungbin, Haertle, Larissa, Banholzer, Nicole, Eiring, Patrick, Danhof, Sophia, Navarro-Aguadero, Miguel Angel, Fernandez-Martin, Adrian, Ortiz-Ruiz, Alejandra, Barrio, Santiago, Gallardo, Miguel, Valeri, Antonio, Castellano, Eva, Raab, Peter, Rudert, Maximilian, Haferlach, Claudia, Sauer, Markus, Hudecek, Michael, Martinez-Lopez, J., Waldschmidt, Johannes, Einsele, Hermann, Rasche, Leo, Kortüm, K. Martin

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