Microbiota-Dependent Sequelae of Acute Infection Compromise Tissue-Specific Immunity von Fonseca, Denise Morais da, Hand, Timothy W., Han, Seong-Ji, Gerner, Michael Y., Zaretsky, Arielle Glatman, Byrd, Allyson L., Harrison, Oliver J., Ortiz, Alexandra M., Quinones, Mariam, Trinchieri, Giorgio, Brenchley, Jason M., Brodsky, Igor E., Germain, Ronald N., Randolph, Gwendalyn J., Belkaid, Yasmine

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Tissue Myeloid Cells in SIV-Infected Primates Acquire Viral DNA through Phagocytosis of Infected T Cells von Calantone, Nina, Wu, Fan, Klase, Zachary, Deleage, Claire, Perkins, Molly, Matsuda, Kenta, Thompson, Elizabeth A., Ortiz, Alexandra M., Vinton, Carol L., Ourmanov, Ilnour, Loré, Karin, Douek, Daniel C., Estes, Jacob D., Hirsch, Vanessa M., Brenchley, Jason M.

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Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques von Vujkovic-Cvijin, Ivan, Swainson, Louise A., Chu, Simon N., Ortiz, Alexandra M., Santee, Clark A., Petriello, Annalise, Dunham, Richard M., Fadrosh, Douglas W., Lin, Din L., Faruqi, Ali A., Huang, Yong, Apetrei, Cristian, Pandrea, Ivona, Hecht, Frederick M., Pilcher, Christopher D., Klatt, Nichole R., Brenchley, Jason M., Lynch, Susan V., McCune, Joseph M.

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CD4 depletion in SIV-infected macaques results in macrophage and microglia infection with rapid turnover of infected cells von Micci, Luca, Alvarez, Xavier, Iriele, Robin I, Ortiz, Alexandra M, Ryan, Emily S, McGary, Colleen S, Deleage, Claire, McAtee, Brigitte B, He, Tianyu, Apetrei, Cristian, Easley, Kirk, Pahwa, Savita, Collman, Ronald G, Derdeyn, Cynthia A, Davenport, Miles P, Estes, Jacob D, Silvestri, Guido, Lackner, Andrew A, Paiardini, Mirko

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Multiple modes of antigen exposure induce clonotypically diverse epitope-specific CD8+ T cells across multiple tissues in nonhuman primates von Simpson, Jennifer, Starke, Carly E., Ortiz, Alexandra M., Ransier, Amy, Darko, Sam, Douek, Daniel C., Brenchley, Jason M.

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Correction: Mitigation of endemic GI-tract pathogen-mediated inflammation through development of multimodal treatment regimen and its impact on SIV acquisition in rhesus macaques von Bochart, Rachele M, Busman-Sahay, Kathleen, Bondoc, Stephen, Morrow, David W, Ortiz, Alexandra M, Fennessey, Christine M, Fischer, Miranda B, Shiel, Oriene, Swanson, Tonya, Shriver-Munsch, Christine M, Crank, Hugh B, Armantrout, Kimberly M, Barber-Axthelm, Aaron M, Langner, Charlotte, Moats, Cassandra R, Labriola, Caralyn S, MacAllister, Rhonda, Axthelm, Michael K, Brenchley, Jason M, Keele, Brandon F, Estes, Jacob D, Hansen, Scott G, Smedley, Jeremy V

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Butyrate administration is not sufficient to improve immune reconstitution in antiretroviral-treated SIV-infected macaques von Ortiz, Alexandra M., Simpson, Jennifer, Langner, Charlotte A., Baker, Phillip J., Aguilar, Cynthia, Brooks, Kelsie, Flynn, Jacob K., Vinton, Carol L., Rahmberg, Andrew R., Hickman, Heather D., Brenchley, Jason M.

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Experimental bacterial dysbiosis with consequent immune alterations increase intrarectal SIV acquisition susceptibility von Ortiz, Alexandra M., Baker, Phillip J., Langner, Charlotte A., Simpson, Jennifer, Stacy, Apollo, Flynn, Jacob K., Starke, Carly E., Vinton, Carol L., Fennessey, Christine M., Belkaid, Yasmine, Keele, Brandon F., Brenchley, Jason M.

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Host Genetics and Environment Shape the Composition of the Gastrointestinal Microbiome in Nonhuman Primates von Flynn, Jacob K, Ortiz, Alexandra M, Herbert, Richard, Brenchley, Jason M

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The Vaginal Microbiome of Nonhuman Primates Can Be Only Transiently Altered to Become Lactobacillus Dominant without Reducing Inflammation von Langner, Charlotte A, Ortiz, Alexandra M, Flynn, Jacob K, Kendall, Heather, Lagenaur, Laurel A, Brenchley, Jason M

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Multifunctional double-negative T cells in sooty mangabeys mediate T-helper functions irrespective of SIV infection von Sundaravaradan, Vasudha, Saleem, Ramsey, Micci, Luca, Gasper, Melanie A, Ortiz, Alexandra M, Else, James, Silvestri, Guido, Paiardini, Mirko, Aitchison, John D, Sodora, Donald L

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Simian Immunodeficiency Virus Infection of Rhesus Macaques Results in Delayed Zika Virus Clearance von Vinton, Carol L, Magaziner, Samuel J, Dowd, Kimberly A, Robertson, Shelly J, Amaro-Carambot, Emerito, Karmele, Erik P, Ortiz, Alexandra M, Starke, Carly E, Mudd, Joseph C, Whitehead, Stephen S, Best, Sonja M, Pierson, Theodore C, Hickman, Heather D, Brenchley, Jason M

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Analysis of the In Vivo Turnover of CD4+ T-Cell Subsets in Chronically SIV-Infected Sooty Mangabeys von Ortiz, Alexandra M, Carnathan, Diane G, Yu, Joana, Sheehan, Katherine M, Kim, Peter, Reynaldi, Arnold, Vanderford, Thomas H, Klatt, Nichole R, Brenchley, Jason M, Davenport, Miles P, Silvestri, Guido

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2-Hydroxypropyl-β-Cyclodextrin Treatment Induces Modest Immune Activation in Healthy Rhesus Macaques von Ortiz, Alexandra M, Castello Casta, Fabiola, Rahmberg, Andrew, Markowitz, Tovah E, Brooks, Kelsie, Simpson, Jennifer, Brenchley, Jason M

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Microbiome Studies in Non-human Primates von Brenchley, Jason M., Ortiz, Alexandra M.

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SIV infection and ARV treatment reshape the transcriptional and epigenetic profile of naïve and memory T cells in vivo von Rahmberg, Andrew R, Markowitz, Tovah E, Mudd, Joseph C, Ortiz, Alexandra M, Brenchley, Jason M

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Biomarkers of Cellular Stress Do Not Associate with sCD14 in Progressive HIV and SIV Infections in Vivo von Vinton, Carol L, Starke, Carly E, Ortiz, Alexandra M, Lai, Stephen H, Flynn, Jacob K, Sortino, Ornella, Knox, Kenneth, Sereti, Irini, Brenchley, Jason M

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CD4+ T Cells Support Production of Simian Immunodeficiency Virus Env Antibodies That Enforce CD4-Dependent Entry and Shape Tropism In Vivo von Francella, Nicholas, Gwyn, Sarah E, Yi, Yanjie, Li, Bing, Xiao, Peng, Elliott, Sarah T C, Ortiz, Alexandra M, Hoxie, James A, Paiardini, Mirko, Silvestri, Guido, Derdeyn, Cynthia A, Collman, Ronald G

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Antiretroviral Therapy Administration in Healthy Rhesus Macaques Is Associated with Transient Shifts in Intestinal Bacterial Diversity and Modest Immunological Perturbations von Ortiz, Alexandra M, Flynn, Jacob K, DiNapoli, Sarah R, Sortino, Ornella, Vujkovic-Cvijin, Ivan, Belkaid, Yasmine, Sereti, Irini, Brenchley, Jason M

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SARS-CoV-2 infection perturbs the gastrointestinal tract and induces modest microbial translocation across the intestinal barrier von Brooks, Kelsie, Nelson, Christine E, Aguilar, Cynthia, Hoang, Timothy N, Ortiz, Alexandra M, Langner, Charlotte A, Yee, Debra S, Flynn, Jacob K, Vrba, Sophia, Laidlaw, Elizabeth, Vannella, Kevin M, Grazioli, Alison, Saharia, Kapil K, Purcell, Madeleine, Singireddy, Shreya, Wu, Jocelyn, Stankiewicz, Jason, Chertow, Daniel S, Sereti, Irini, Paiardini, Mirko, Hickman, Heather D, Via, Laura E, Barber, Daniel L, Brenchley, Jason M

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