Pathogenesis of amyotrophic lateral sclerosis von Morgan, Sarah, Orrell, Richard W

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C9orf72 expansions in frontotemporal dementia and amyotrophic lateral sclerosis von Rohrer, Jonathan D, Dr, Isaacs, Adrian M, PhD, Mizielinska, Sarah, PhD, Mead, Simon, Prof, Lashley, Tammaryn, PhD, Wray, Selina, PhD, Sidle, Katie, PhD, Fratta, Pietro, PhD, Orrell, Richard W, MD, Hardy, John, Prof, Holton, Janice, PhD, Revesz, Tamas, Prof, Rossor, Martin N, Prof, Warren, Jason D, Prof

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Pathogenic VCP Mutations Induce Mitochondrial Uncoupling and Reduced ATP Levels von Bartolome, Fernando, Wu, Hsiu-Chuan, Burchell, Victoria S., Preza, Elisavet, Wray, Selina, Mahoney, Colin J., Fox, Nick C., Calvo, Andrea, Canosa, Antonio, Moglia, Cristina, Mandrioli, Jessica, Chiò, Adriano, Orrell, Richard W., Houlden, Henry, Hardy, John, Abramov, Andrey Y., Plun-Favreau, Helene

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Large C9orf72 Hexanucleotide Repeat Expansions Are Seen in Multiple Neurodegenerative Syndromes and Are More Frequent Than Expected in the UK Population von Beck, Jon, Poulter, Mark, Hensman, Davina, Rohrer, Jonathan D., Mahoney, Colin J., Adamson, Gary, Campbell, Tracy, Uphill, James, Borg, Aaron, Fratta, Pietro, Orrell, Richard W., Malaspina, Andrea, Rowe, James, Brown, Jeremy, Hodges, John, Sidle, Katie, Polke, James M., Houlden, Henry, Schott, Jonathan M., Fox, Nick C., Rossor, Martin N., Tabrizi, Sarah J., Isaacs, Adrian M., Hardy, John, Warren, Jason D., Collinge, John, Mead, Simon

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Analysis of amyotrophic lateral sclerosis as a multistep process: a population-based modelling study von Al-Chalabi, Ammar, Prof, Calvo, Andrea, MD, Chio, Adriano, Prof, Colville, Shuna, MPH, Ellis, Cathy M, PhD, Hardiman, Orla, Prof, Heverin, Mark, MSc, Howard, Robin S, PhD, Huisman, Mark H B, MD, Keren, Noa, MBBS, Leigh, P Nigel, Prof, Mazzini, Letizia, MD, Mora, Gabriele, MD, Orrell, Richard W, MD, Rooney, James, MSc, Scott, Kirsten M, MBBS, Scotton, William J, MBioch, Seelen, Meinie, MD, Shaw, Christopher E, Prof, Sidle, Katie S, PhD, Swingler, Robert, MD, Tsuda, Miho, MBChB, Veldink, Jan H, Prof, Visser, Anne E, MD, van den Berg, Leonard H, Prof, Pearce, Neil, Prof

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Pharmacological treatments for Friedreich ataxia von Kearney, Mary, Orrell, Richard W, Fahey, Michael, Brassington, Ruth, Pandolfo, Massimo, Kearney, Mary

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A comprehensive analysis of rare genetic variation in amyotrophic lateral sclerosis in the UK von Morgan, Sarah, Shatunov, Aleksey, Sproviero, William, Jones, Ashley R, Shoai, Maryam, Hughes, Deborah, Al Khleifat, Ahmad, Malaspina, Andrea, Morrison, Karen E, Shaw, Pamela J, Shaw, Christopher E, Sidle, Katie, Orrell, Richard W, Fratta, Pietro, Hardy, John, Pittman, Alan, Al-Chalabi, Ammar

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Opinion: more mouse models and more translation needed for ALS von Fisher, Elizabeth M C, Greensmith, Linda, Malaspina, Andrea, Fratta, Pietro, Hanna, Michael G, Schiavo, Giampietro, Isaacs, Adrian M, Orrell, Richard W, Cunningham, Thomas J, Arozena, Abraham Acevedo

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Safety, pharmacokinetic, and functional effects of the nogo-a monoclonal antibody in amyotrophic lateral sclerosis: a randomized, first-in-human clinical trial von Meininger, Vincent, Pradat, Pierre-François, Corse, Andrea, Al-Sarraj, Safa, Rix Brooks, Benjamin, Caress, James B, Cudkowicz, Merit, Kolb, Stephen J, Lange, Dale, Leigh, P Nigel, Meyer, Thomas, Milleri, Stefano, Morrison, Karen E, Orrell, Richard W, Peters, Gary, Rothstein, Jeffrey D, Shefner, Jeremy, Lavrov, Arseniy, Williams, Nicola, Overend, Phil, Price, Jeffrey, Bates, Stewart, Bullman, Jonathan, Krull, David, Berges, Alienor, Abila, Bams, Meno-Tetang, Guy, Wurthner, Jens

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Plasma neurofilament heavy chain levels and disease progression in amyotrophic lateral sclerosis: insights from a longitudinal study von Lu, Ching-Hua, Petzold, Axel, Topping, Jo, Allen, Kezia, Macdonald-Wallis, Corrie, Clarke, Jan, Pearce, Neil, Kuhle, Jens, Giovannoni, Gavin, Fratta, Pietro, Sidle, Katie, Fish, Mark, Orrell, Richard, Howard, Robin, Greensmith, Linda, Malaspina, Andrea

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The chromosome 9 ALS and FTD locus is probably derived from a single founder von Mok, Kin, Traynor, Bryan J, Schymick, Jennifer, Tienari, Pentti J, Laaksovirta, Hannu, Peuralinna, Terhi, Myllykangas, Liisa, Chiò, Adriano, Shatunov, Aleksey, Boeve, Bradley F, Boxer, Adam L, DeJesus-Hernandez, Mariely, Mackenzie, Ian R, Waite, Adrian, Williams, Nigel, Morris, Huw R, Simón-Sánchez, Javier, van Swieten, John C, Heutink, Peter, Restagno, Gabriella, Mora, Gabriele, Morrison, Karen E, Shaw, Pamela J, Rollinson, Pamela Sara, Al-Chalabi, Ammar, Rademakers, Rosa, Pickering-Brown, Stuart, Orrell, Richard W, Nalls, Michael A, Hardy, John

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Systemic inflammatory response and neuromuscular involvement in amyotrophic lateral sclerosis von Lu, Ching-Hua, Allen, Kezia, Oei, Felicia, Leoni, Emanuela, Kuhle, Jens, Tree, Timothy, Fratta, Pietro, Sharma, Nikhil, Sidle, Katie, Howard, Robin, Orrell, Richard, Fish, Mark, Greensmith, Linda, Pearce, Neil, Gallo, Valentina, Malaspina, Andrea

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Investigation of white matter pathology in ALS and PLS using tract-based spatial statistics von Ciccarelli, Olga, Behrens, Timothy E., Johansen-Berg, Heidi, Talbot, Kevin, Orrell, Richard W., Howard, Robin S., Nunes, Rita G., Miller, David H., Matthews, Paul M., Thompson, Alan J., Smith, Stephen M.

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β-catenin is central to DUX4-driven network rewiring in facioscapulohumeral muscular dystrophy von Banerji, Christopher R. S., Knopp, Paul, Moyle, Louise A., Severini, Simone, Orrell, Richard W., Teschendorff, Andrew E., Zammit, Peter S.

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Screening a UK amyotrophic lateral sclerosis cohort provides evidence of multiple origins of the C9orf72 expansion von Fratta, Pietro, Polke, James M, Newcombe, Jia, Mizielinska, Sarah, Lashley, Tammaryn, Poulter, Mark, Beck, Jon, Preza, Elisavet, Devoy, Anny, Sidle, Katie, Howard, Robin, Malaspina, Andrea, Orrell, Richard W, Clarke, Jan, Lu, Ching-Hua, Mok, Kin, Collins, Toby, Shoaii, Maryam, Nanji, Tina, Wray, Selina, Adamson, Gary, Pittman, Alan, Renton, Alan E, Traynor, Bryan J, Sweeney, Mary G, Revesz, Tamas, Houlden, Henry, Mead, Simon, Isaacs, Adrian M, Fisher, Elizabeth M.C

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Antioxidants and other pharmacological treatments for Friedreich ataxia von Kearney, Mary, Orrell, Richard W, Fahey, Michael, Pandolfo, Massimo

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The IGF-I splice variant MGF increases progenitor cells in ALS, dystrophic, and normal muscle von Ates, Kenan, Yang, Shi Yu, Orrell, Richard W., Sinanan, Andrea C.M., Simons, Paul, Solomon, Andrew, Beech, Steven, Goldspink, Geoffrey, Lewis, Mark P.

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DiPALS: Diaphragm Pacing in patients with Amyotrophic Lateral Sclerosis - a randomised controlled trial von McDermott, Christopher J, Bradburn, Mike J, Maguire, Chin, Cooper, Cindy L, Baird, Wendy O, Baxter, Susan K, Cohen, Judith, Cantrill, Hannah, Dixon, Simon, Ackroyd, Roger, Baudouin, Simon, Bentley, Andrew, Berrisford, Richard, Bianchi, Stephen, Bourke, Stephen C, Darlison, Roy, Ealing, John, Elliott, Mark, Fitzgerald, Patrick, Galloway, Simon, Hamdalla, Hisham, Hanemann, C Oliver, Hughes, Philip, Imam, Ibrahim, Karat, Dayalan, Leek, Roger, Maynard, Nick, Orrell, Richard W, Sarela, Abeezar, Stradling, John, Talbot, Kevin, Taylor, Lyn, Turner, Martin, Simonds, Anita K, Williams, Tim, Wedzicha, Wisia, Young, Carolyn, Shaw, Pamela J

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Understanding the Causes of Amyotrophic Lateral Sclerosis von Orrell, Richard W

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Design, set-up and utility of the UK facioscapulohumeral muscular dystrophy patient registry von Evangelista, Teresinha, Wood, Libby, Fernandez-Torron, Roberto, Williams, Maggie, Smith, Debbie, Lunt, Peter, Hudson, Judith, Norwood, Fiona, Orrell, Richard, Willis, Tracey, Hilton-Jones, David, Rafferty, Karen, Guglieri, Michela, Lochmüller, Hanns

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