Design and Implementation of the Puerto Rico Observational Study of Psychosocial, Environmental, and Chronic Disease Trends (PROSPECT) von Mattei, Josiemer, Tucker, Katherine L, Falcón, Luis M, Ríos-Bedoya, Carlos F, Kaplan, Robert M, O’Neill, H June, Tamez, Martha, Mendoza, Sigrid, Díaz-Álvarez, Claudia B, Orozco, Jonathan E, Acosta Pérez, Edna, Rodríguez-Orengo, José F

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Pluralismo razonable sin relativismo ético: Respuesta a Sanfélix Vidarte von Dall’Agnol, Darlei

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De novo design of knotted tandem repeat proteins von Doyle, Lindsey A., Takushi, Brittany, Kibler, Ryan D., Milles, Lukas F., Orozco, Carolina T., Jones, Jonathan D., Jackson, Sophie E., Stoddard, Barry L., Bradley, Philip

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Proliferative Neural Stem Cells Have High Endogenous ROS Levels that Regulate Self-Renewal and Neurogenesis in a PI3K/Akt-Dependant Manner von Le Belle, Janel E., Orozco, Nicolas M., Paucar, Andres A., Saxe, Jonathan P., Mottahedeh, Jack, Pyle, April D., Wu, Hong, Kornblum, Harley I.

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Baricitinib plus Remdesivir for Hospitalized Adults with Covid-19 von Kalil, Andre C, Patterson, Thomas F, Mehta, Aneesh K, Tomashek, Kay M, Wolfe, Cameron R, Ghazaryan, Varduhi, Marconi, Vincent C, Ruiz-Palacios, Guillermo M, Hsieh, Lanny, Kline, Susan, Tapson, Victor, Iovine, Nicole M, Jain, Mamta K, Sweeney, Daniel A, El Sahly, Hana M, Branche, Angela R, Regalado Pineda, Justino, Lye, David C, Sandkovsky, Uriel, Luetkemeyer, Anne F, Cohen, Stuart H, Finberg, Robert W, Jackson, Patrick E.H, Taiwo, Babafemi, Paules, Catharine I, Arguinchona, Henry, Erdmann, Nathaniel, Ahuja, Neera, Frank, Maria, Oh, Myoung-don, Kim, Eu-Suk, Tan, Seow Y, Mularski, Richard A, Nielsen, Henrik, Ponce, Philip O, Taylor, Barbara S, Larson, LuAnn, Rouphael, Nadine G, Saklawi, Youssef, Cantos, Valeria D, Ko, Emily R, Engemann, John J, Amin, Alpesh N, Watanabe, Miki, Billings, Joanne, Elie, Marie-Carmelle, Davey, Richard T, Burgess, Timothy H, Ferreira, Jennifer, Green, Michelle, Makowski, Mat, Cardoso, Anabela, de Bono, Stephanie, Bonnett, Tyler, Proschan, Michael, Deye, Gregory A, Dempsey, Walla, Nayak, Seema U, Dodd, Lori E, Beigel, John H

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Mechanistic insights into the rational design of masked antibodies von Orozco, Carolina T., Bersellini, Manuela, Irving, Lorraine M., Howard, Wesley W., Hargreaves, David, Devine, Paul W. A., Siouve, Elise, Browne, Gareth J., Bond, Nicholas J., Phillips, Jonathan J., Ravn, Peter, Jackson, Sophie E.

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All-in-one disulfide bridging enables the generation of antibody conjugates with modular cargo loading von Dannheim, Friederike M, Walsh, Stephen J, Orozco, Carolina T, Hansen, Anders Højgaard, Bargh, Jonathan D, Jackson, Sophie E, Bond, Nicholas J, Parker, Jeremy S, Carroll, Jason S, Spring, David R

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New pyridine‐based chalcones and pyrazolines with anticancer, antibacterial, and antiplasmodial activities von Ramírez‐Prada, Jonathan, Rocha‐Ortiz, Juan S., Orozco, Marta I., Moreno, Pedro, Guevara, Miguel, Barreto, Mauricio, Burbano, Maria E., Robledo, Sara, Crespo‐Ortiz, Maria del Pilar, Quiroga, Jairo, Abonia, Rodrigo, Cuartas, Viviana, Insuasty, Braulio

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Interconversion of Unexpected Thiol States Affects the Stability, Structure, and Dynamics of Antibody Engineered for Site-Specific Conjugation von Orozco, Carolina T, Edgeworth, Matthew J, Devine, Paul W. A, Hines, Alistair R, Cornwell, Owen, Thompson, Christopher, Wang, Xiangyang, Phillips, Jonathan J, Ravn, Peter, Jackson, Sophie E, Bond, Nicholas J

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Confirmation of TNIP1 and IL23A as susceptibility loci for psoriatic arthritis von Bowes, John, Orozco, Gisela, Flynn, Edward, Ho, Pauline, Brier, Rasha, Marzo-Ortega, Helena, Coates, Laura, McManus, Ross, Ryan, Anthony W, Kane, David, Korendowych, Eleanor, McHugh, Neil, FitzGerald, Oliver, Packham, Jonathan, Morgan, Ann W, Bruce, Ian N, Barton, Anne

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SGLT2i treatment during AKI and its association with major adverse kidney events von Alcantar-Vallin, Luz, Zaragoza, Jose J, Díaz-Villavicencio, Bladimir, Hernandez-Morales, Karla, Camacho-Guerrero, Jahir R, Perez-Venegas, Miguel A, Carmona-Morales, Edgar J, Oseguera-Gonzalez, Alexa N, Murguia-Soto, Cesar, Chávez-Alonso, Gael, Arredondo-Dubois, José M, Orozco-Chan, Carlos E, Gómez-Fregoso, Juan A, Rodríguez-García, Francisco G, Navarro-Blackaller, Guillermo, Medina-González, Ramón, Martínez Gallardo-González, Alejandro, Abundis-Mora, Gabriela J, Vega-Vega, Olynka, García-García, Guillermo, Chávez-Iñiguez, Jonathan S

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Quality of sexual life in Mexican men after spinal cord injury von Acosta-Santillán, Paulina Lucia, Toro-Sashida, Maria Fernanda, Rosas-Mendoza, Alejandra Viridiana, Fuentes-Orozco, Clotilde, Jasso-García, Kelvin, García de León-Flores, Paulina, Mellado-Téllez, Mel Paul, Ibarra-Camargo, Silvia Alejandra, Chejfec-Ciociano, Jonathan Matías, Barbosa-Camacho, Francisco José, Flores-Prado, Juan Armando, Cervantes-Guevara, Gabino, Cervantes-Pérez, Enrique, Cevantes-Cardona, Guillermo Alonso, Alvarez-Villaseñor, Andrea Socorro, González-Ojeda, Alejandro

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Baricitinib versus dexamethasone for adults hospitalised with COVID-19 (ACTT-4): a randomised, double-blind, double placebo-controlled trial von Wolfe, Cameron R, Tomashek, Kay M, Mularski, Richard A, Pineda, Justino Regalado, Dretler, Alexandra W, de Castilla, Diego Lopez, Short, William R, McLellan, Susan L F, Iovine, Nicole M, Huprikar, Nikhil, Hohmann, Elizabeth, Kelley, Colleen F, Holodniy, Mark, Finberg, Robert W, Ko, Emily R, Engemann, John J, Ponce, Philip O, Larson, LuAnn, Melendez, Dante Paolo, de Leon, Alfredo Ponce, Cardoso, Anabela, de Bono, Stephanie, Ferreira, Jennifer L, Makowski, Mat, Bonnett, Tyler, Ghazaryan, Varduhi, Nayak, Seema U, Dodd, Lori E, Kalil, Andre C, Patterson, Jan E., Odrobina, Robert, Golamari, Reshma R., Riska, Paul F., Sosa, Nestor, Berhe, Mezgebe, Dishner, Emma, Hubel, Kinsley, Bautista Felix, Nora, Bechnak, Amer Ryan, Saklawi, Youssef, Walsh, Edward E., Falsey, Ann R., Olbrich, Norman, Levine, Corri, Kim, Hyun, Whitaker, Jennifer A., Luetkemeyer, Anne F., Bainbridge, Emma, Bhamidipati, Divya R., Nithin Gopalsamy, Srinivasa, Chary, Aarthi, Kim, Hong Bin, Benson, Constance A., McConnell, Kimberly, Wang, Jennifer P., Wessolossky, Mireya, Berjohn, Catherine, Utz, Gregory C., Bell, Taison D., Colombo, Christopher J., Colombo, Rhonda E., Tapson, Victor F., Grein, Jonathan, Sutterwala, Fayyaz, Ince, Dilek, Fung, Monica, Wyles, David, Sarcone, Ellen, Neumann, Henry, Hochman, Sarah, Mulligan, Mark, Eckhardt, Benjamin, Carmody, Ellie, Nadeau, Kari, Bessesen, Mary, Lambert, Allison A., Alicic, Radica Z., Saito, Sho, Hsieh, Lanny, Amin, Alpesh N., Candiotti, Keith A., Castro, Jose G., Antor, Maria A., Lalani, Tahaniyat, Borgetti, Scott A., Hoft, Daniel F., Chakrabarty, Melony, Lindholm, David A., Wellington, Trevor R., Husson, Jennifer S., Levine, Andrea R., Shafi, Humaira, Burgess, Timothy H., Nieuwoudt, Christina, Hill, Heather, Pettibone, Stephanie, Deye, Gregory A., Jurao, Robert, Koo, Hyung, Proschan, Michael

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Artificial intelligence-based strategies to identify patient populations and advance analysis in age-related macular degeneration clinical trials von Yaghy, Antonio, Lee, Aaron Y., Keane, Pearse A., Keenan, Tiarnan D.L., Mendonca, Luisa S.M., Lee, Cecilia S., Cairns, Anne Marie, Carroll, Joseph, Chen, Hao, Clark, Julie, Cukras, Catherine A., de Sisternes, Luis, Domalpally, Amitha, Durbin, Mary K., Goetz, Kerry E., Grassmann, Felix, Haines, Jonathan L., Honda, Naoto, Hu, Zhihong Jewel, Mody, Christopher, Orozco, Luz D., Owsley, Cynthia, Poor, Stephen, Reisman, Charles, Ribeiro, Ramiro, Sadda, Srinivas R., Sivaprasad, Sobha, Staurenghi, Giovanni, Ting, Daniel SW, Tumminia, Santa J., Zalunardo, Luca, Waheed, Nadia K.

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Rayleigh scattering in an optical nanofiber as a probe of higher-order mode propagation von Hoffman, Jonathan E., Fatemi, Fredrik K., Beadie, Guy, Rolston, Steven L., Orozco, Luis A.

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Systolic Blood Pressure and the Risk of Kidney Replacement Therapy and Mortality in Patients with Chronic Kidney Disease Stages 4–5 von Chávez-Iñiguez, Jonathan S., Zaragoza, Jose J., Camacho-Guerrero, Jahir R., Villavicencio-Cerón, Vanessa, Valdez-Ortiz, Rafael, Huerta-Orozco, Ana E., Chávez-Alonso, Gael, Oliva-Martinez, Ana E., Díaz-Villavicencio, Bladimir, Calderón-García, Clementina E., González-Barajas, Jose D., Arizaga-Nápoles, Manuel, De La Vega-Méndez, Frida M., Gómez-Fregoso, Juan A., Rodríguez-García, Francisco G., Navarro-Blackaller, Guillermo, Medina-González, Ramón, Alcantar-Vallin, Luz, García-García, Guillermo

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Efficacy of interferon beta-1a plus remdesivir compared with remdesivir alone in hospitalised adults with COVID-19: a double-bind, randomised, placebo-controlled, phase 3 trial von Kalil, Andre C, Mehta, Aneesh K, Patterson, Thomas F, Erdmann, Nathaniel, Gomez, Carlos A, Jain, Mamta K, Wolfe, Cameron R, Ruiz-Palacios, Guillermo M, Kline, Susan, Regalado Pineda, Justino, Luetkemeyer, Anne F, Harkins, Michelle S, Jackson, Patrick E H, Iovine, Nicole M, Tapson, Victor F, Oh, Myoung-Don, Whitaker, Jennifer A, Mularski, Richard A, Paules, Catharine I, Ince, Dilek, Takasaki, Jin, Sweeney, Daniel A, Sandkovsky, Uriel, Wyles, David L, Hohmann, Elizabeth, Grimes, Kevin A, Grossberg, Robert, Laguio-Vila, Maryrose, Lambert, Allison A, Lopez de Castilla, Diego, Kim, EuSuk, Larson, LuAnn, Wan, Claire R, Traenkner, Jessica J, Ponce, Philip O, Patterson, Jan E, Goepfert, Paul A, Sofarelli, Theresa A, Mocherla, Satish, Ko, Emily R, Ponce de Leon, Alfredo, Doernberg, Sarah B, Atmar, Robert L, Maves, Ryan C, Dangond, Fernando, Ferreira, Jennifer, Green, Michelle, Makowski, Mat, Bonnett, Tyler, Beresnev, Tatiana, Ghazaryan, Varduhi, Dempsey, Walla, Nayak, Seema U, Dodd, Lori, Tomashek, Kay M, Beigel, John H

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Capture Hi-C identifies a novel causal gene, IL20RA, in the pan-autoimmune genetic susceptibility region 6q23 von McGovern, Amanda, Schoenfelder, Stefan, Martin, Paul, Massey, Jonathan, Duffus, Kate, Plant, Darren, Yarwood, Annie, Pratt, Arthur G, Anderson, Amy E, Isaacs, John D, Diboll, Julie, Thalayasingam, Nishanthi, Ospelt, Caroline, Barton, Anne, Worthington, Jane, Fraser, Peter, Eyre, Stephen, Orozco, Gisela

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Modal interference in optical nanofibers for sub-Angstrom radius sensitivity von Fatemi, Fredrik K., Hoffman, Jonathan E., Solano, Pablo, Fenton, Eliot F., Beadie, Guy, Rolston, Steven L., Orozco, Luis A.

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Evidence for transcript networks composed of chimeric RNAs in human cells von Djebali, Sarah, Lagarde, Julien, Kapranov, Philipp, Lacroix, Vincent, Borel, Christelle, Mudge, Jonathan M, Howald, Cédric, Foissac, Sylvain, Ucla, Catherine, Chrast, Jacqueline, Ribeca, Paolo, Martin, David, Murray, Ryan R, Yang, Xinping, Ghamsari, Lila, Lin, Chenwei, Bell, Ian, Dumais, Erica, Drenkow, Jorg, Tress, Michael L, Gelpí, Josep Lluís, Orozco, Modesto, Valencia, Alfonso, van Berkum, Nynke L, Lajoie, Bryan R, Vidal, Marc, Stamatoyannopoulos, John, Batut, Philippe, Dobin, Alex, Harrow, Jennifer, Hubbard, Tim, Dekker, Job, Frankish, Adam, Salehi-Ashtiani, Kourosh, Reymond, Alexandre, Antonarakis, Stylianos E, Guigó, Roderic, Gingeras, Thomas R

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