Smoothened Variants Explain the Majority of Drug Resistance in Basal Cell Carcinoma von Atwood, Scott X., Sarin, Kavita Y., Whitson, Ramon J., Li, Jiang R., Kim, Geurim, Rezaee, Melika, Ally, Mina S., Kim, Jinah, Yao, Catherine, Chang, Anne Lynn S., Oro, Anthony E., Tang, Jean Y.

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An Investigator-Initiated Open-Label Trial of Sonidegib in Advanced Basal Cell Carcinoma Patients Resistant to Vismodegib von Danial, Christina, Sarin, Kavita Y, Oro, Anthony E, Chang, Anne Lynn S

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Shh maintains dermal papilla identity and hair morphogenesis via a Noggin-Shh regulatory loop von Woo, Wei-Meng, Zhen, Hanson H, Oro, Anthony E

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Efficacy and Safety of Vismodegib in Advanced Basal-Cell Carcinoma von Sekulic, Aleksandar, Migden, Michael R, Oro, Anthony E, Dirix, Luc, Lewis, Karl D, Hainsworth, John D, Solomon, James A, Yoo, Simon, Arron, Sarah T, Friedlander, Philip A, Marmur, Ellen, Rudin, Charles M, Chang, Anne Lynn S, Low, Jennifer A, Mackey, Howard M, Yauch, Robert L, Graham, Richard A, Reddy, Josina C, Hauschild, Axel

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Epigenetic targeting of Hedgehog pathway transcriptional output through BET bromodomain inhibition von Tang, Yujie, Gholamin, Sharareh, Schubert, Simone, Willardson, Minde I, Lee, Alex, Bandopadhayay, Pratiti, Bergthold, Guillame, Masoud, Sabran, Nguyen, Brian, Vue, Nujsaubnusi, Balansay, Brianna, Yu, Furong, Oh, Sekyung, Woo, Pamelyn, Chen, Spenser, Ponnuswami, Anitha, Monje, Michelle, Atwood, Scott X, Whitson, Ramon J, Mitra, Siddhartha, Cheshier, Samuel H, Qi, Jun, Beroukhim, Rameen, Tang, Jean Y, Wechsler-Reya, Rob, Oro, Anthony E, Link, Brian A, Bradner, James E, Cho, Yoon-Jae

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AP-1 and TGFß cooperativity drives non-canonical Hedgehog signaling in resistant basal cell carcinoma von Yao, Catherine D., Haensel, Daniel, Gaddam, Sadhana, Patel, Tiffany, Atwood, Scott X., Sarin, Kavita Y., Whitson, Ramon J., McKellar, Siegen, Shankar, Gautam, Aasi, Sumaira, Rieger, Kerri, Oro, Anthony E.

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A conserved YAP/Notch/REST network controls the neuroendocrine cell fate in the lungs von Shue, Yan Ting, Drainas, Alexandros P., Li, Nancy Yanzhe, Pearsall, Sarah M., Morgan, Derrick, Sinnott-Armstrong, Nasa, Hipkins, Susan Q., Coles, Garry L., Lim, Jing Shan, Oro, Anthony E., Simpson, Kathryn L., Dive, Caroline, Sage, Julien

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RAS/MAPK Activation Drives Resistance to Smo Inhibition, Metastasis, and Tumor Evolution in Shh Pathway-Dependent Tumors von Zhao, Xuesong, Ponomaryov, Tatyana, Ornell, Kimberly J, Zhou, Pengcheng, Dabral, Sukriti K, Pak, Ekaterina, Li, Wei, Atwood, Scott X, Whitson, Ramon J, Chang, Anne Lynn S, Li, Jiang, Oro, Anthony E, Chan, Jennifer A, Kelleher, Joseph F, Segal, Rosalind A

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Actin polymerization controls cilia-mediated signaling von Drummond, Michael L, Li, Mischa, Tarapore, Eric, Nguyen, Tuyen T L, Barouni, Baina J, Cruz, Shaun, Tan, Kevin C, Oro, Anthony E, Atwood, Scott X

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Hedgehog pathway inhibition and the race against tumor evolution von Atwood, Scott X, Chang, Anne Lynn S, Oro, Anthony E

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Basal-to-inflammatory transition and tumor resistance via crosstalk with a pro-inflammatory stromal niche von Li, Nancy Yanzhe, Zhang, Weiruo, Haensel, Daniel, Jussila, Anna R., Pan, Cory, Gaddam, Sadhana, Plevritis, Sylvia K., Oro, Anthony E.

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Loss of Primary Cilia Drives Switching from Hedgehog to Ras/MAPK Pathway in Resistant Basal Cell Carcinoma von Kuonen, François, Huskey, Noelle E., Shankar, Gautam, Jaju, Prajakta, Whitson, Ramon J., Rieger, Kerri E., Atwood, Scott X., Sarin, Kavita Y., Oro, Anthony E.

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Noncanonical hedgehog pathway activation through SRF–MKL1 promotes drug resistance in basal cell carcinomas von Whitson, Ramon J, Lee, Alex, Urman, Nicole M, Mirza, Amar, Yao, Catherine Y, Brown, Alexander S, Li, Jiang R, Shankar, Gautam, Fry, Micah A, Atwood, Scott X, Lee, Eunice Y, Hollmig, S Tyler, Aasi, Sumaira Z, Sarin, Kavita Y, Scott, Matthew P, Epstein, Ervin H, Tang, Jean Y, Oro, Anthony E

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Skin basal cell carcinomas assemble a pro-tumorigenic spatially organized and self-propagating Trem2+ myeloid niche von Haensel, Daniel, Daniel, Bence, Gaddam, Sadhana, Pan, Cory, Fabo, Tania, Bjelajac, Jeremy, Jussila, Anna R., Gonzalez, Fernanda, Li, Nancy Yanzhe, Chen, Yun, Hou, JinChao, Patel, Tiffany, Aasi, Sumaira, Satpathy, Ansuman T., Oro, Anthony E.

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TFAP2C- and p63-Dependent Networks Sequentially Rearrange Chromatin Landscapes to Drive Human Epidermal Lineage Commitment von Li, Lingjie, Wang, Yong, Torkelson, Jessica L., Shankar, Gautam, Pattison, Jillian M., Zhen, Hanson H., Fang, Fengqin, Duren, Zhana, Xin, Jingxue, Gaddam, Sadhana, Melo, Sandra P., Piekos, Samantha N., Li, Jiang, Liaw, Eric J., Chen, Lang, Li, Rui, Wernig, Marius, Wong, Wing H., Chang, Howard Y., Oro, Anthony E.

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MIM and Cortactin Antagonism Regulates Ciliogenesis and Hedgehog Signaling von Bershteyn, Marina, Atwood, Scott X., Woo, Wei-Meng, Li, Mischa, Oro, Anthony E.

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LY6D marks pre-existing resistant basosquamous tumor subpopulations von Haensel, Daniel, Gaddam, Sadhana, Li, Nancy Y., Gonzalez, Fernanda, Patel, Tiffany, Cloutier, Jeffrey M., Sarin, Kavita Y., Tang, Jean Y., Rieger, Kerri E., Aasi, Sumaira Z., Oro, Anthony E.

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Biomedical Data Commons (BMDC) prioritizes B-lymphocyte non-coding genetic variants in Type 1 Diabetes von Piekos, Samantha N, Gaddam, Sadhana, Bhardwaj, Pranav, Radhakrishnan, Prashanth, Guha, Ramanathan V, Oro, Anthony E

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Conditional telomerase induction causes proliferation of hair follicle stem cells von Sarin, Kavita Y., Cheung, Peggie, Gilison, Daniel, Lee, Eunice, Tennen, Ruth I., Wang, Estee, Artandi, Maja K., Oro, Anthony E., Artandi, Steven E.

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Somatic Correction of Junctional Epidermolysis Bullosa by a Highly Recombinogenic AAV Variant von Melo, Sandra P, Lisowski, Leszek, Bashkirova, Elizaveta, Zhen, Hanson H, Chu, Kirk, Keene, Douglas R, Marinkovich, M Peter, Kay, Mark A, Oro, Anthony E

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