Identification of treatment‐induced vulnerabilities in pancreatic cancer patients using functional model systems von Peschke, Katja, Jakubowsky, Hannah, Schäfer, Arlett, Maurer, Carlo, Lange, Sebastian, Orben, Felix, Bernad, Raquel, Harder, Felix N, Eiber, Matthias, Öllinger, Rupert, Steiger, Katja, Schlitter, Melissa, Weichert, Wilko, Mayr, Ulrich, Phillip, Veit, Schlag, Christoph, Schmid, Roland M, Braren, Rickmer F, Kong, Bo, Demir, Ihsan Ekin, Friess, Helmut, Rad, Roland, Saur, Dieter, Schneider, Günter, Reichert, Maximilian

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Comparison of endoscopic ultrasound-guided fine-needle aspiration and fine-needle biopsy to generate pancreatic cancer organoids: Randomized trial von Wiessner, Johannes Roman, Orben, Felix, Schäfer, Arlett, Fricke, Lisa, Schneider, Günter, Reichert, Maximilian, Herner, Alexander, Mayr, Ulrich, Phillip, Veit, Treiber, Matthias, von Figura, Guido, Abdelhafez, Mohamed, Schmid, Roland M., Schlag, Christoph

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Implementing cell-free DNA of pancreatic cancer patient-derived organoids for personalized oncology von Dantes, Zahra, Yen, Hsi-Yu, Pfarr, Nicole, Winter, Christof, Steiger, Katja, Muckenhuber, Alexander, Hennig, Alexander, Lange, Sebastian, Engleitner, Thomas, Oellinger, Rupert, Maresch, Roman, Orben, Felix, Heid, Irina, Kaissis, Georgios, Shi, Kuangyu, Topping, Geoffrey, Stoegbauer, Fabian, Wirth, Matthias, Peschke, Katja, Papargyriou, Aristeidis, Rezaee-Oghazi, Massoud, Feldmann, Karin, Schaefer, Arlett P. G., Ranjan, Raphela, Lubeseder-Martellato, Clara, Stange, Daniel E., Welsch, Thilo, Martignoni, Marc, Ceyhan, Gueralp O., Friess, Helmut, Herner, Alexander, Liotta, Lucia, Treiber, Matthias, Figura, Guido von, Abdelhafez, Mohamed, Klare, Peter, Schlag, Christoph, Alguel, Hana, Siveke, Jens, Braren, Rickmer, Weirich, Gregor, Weichert, Wilko, Saur, Dieter, Rad, Roland, Schmid, Roland M., Schneider, Guenter, Reichert, Maximilian

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Epigenetic drug screening defines a PRMT5 inhibitor-sensitive pancreatic cancer subtype von Orben, Felix, Lankes, Katharina, Schneeweis, Christian, Hassan, Zonera, Jakubowsky, Hannah, Krauß, Lukas, Boniolo, Fabio, Schneider, Carolin, Schäfer, Arlett, Murr, Janine, Schlag, Christoph, Kong, Bo, Öllinger, Rupert, Wang, Chengdong, Beyer, Georg, Mahajan, Ujjwal M, Xue, Yonggan, Mayerle, Julia, Schmid, Roland M, Kuster, Bernhard, Rad, Roland, Braun, Christian J, Wirth, Matthias, Reichert, Maximilian, Saur, Dieter, Schneider, Günter

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Indirect targeting of MYC sensitizes pancreatic cancer cells to mechanistic target of rapamycin (mTOR) inhibition von Schneeweis, Christian, Hassan, Zonera, Ascherl, Katja, Wirth, Matthias, Koutsouli, Stella, Orben, Felix, Krauß, Lukas, Schneider, Carolin, Öllinger, Rupert, Krämer, Oliver H., Rad, Roland, Reichert, Maximilian, Robles, Maria S., Saur, Dieter, Schneider, Günter

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SUMO pathway inhibition targets an aggressive pancreatic cancer subtype von Biederstädt, Alexander, Hassan, Zonera, Schneeweis, Christian, Schick, Markus, Schneider, Lara, Muckenhuber, Alexander, Hong, Yingfen, Siegers, Gerrit, Nilsson, Lisa, Wirth, Matthias, Dantes, Zahra, Steiger, Katja, Schunck, Kathrin, Langston, Steve, Lenhof, H-P, Coluccio, Andrea, Orben, Felix, Slawska, Jolanta, Scherger, Anna, Saur, Dieter, Müller, Stefan, Rad, Roland, Weichert, Wilko, Nilsson, Jonas, Reichert, Maximilian, Schneider, Günter, Keller, Ulrich

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Mo1222: LABEL-FREE DIGITAL HOLOGRAPHIC MICROSCOPY TO CHARACTERIZE INTER- AND INTRATUMORAL HETEROGENEITY IN PANCREATIC CANCER von Peschke, Katja, Lengl, Manuel, Röhrl, Stefan, Maurer, Carlo, Klenk, Christian, Fresacher, David, Harb, Farid, Hafez, Nawal, Orben, Felix, Öllinger, Rupert, Madej, Joanna, Saur, Dieter, Rad, Roland, Schneider, Gunter, Hayden, Oliver, Diepold, Klaus, Reichert, Maximillian

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NOXA expression drives synthetic lethality to RUNX1 inhibition in pancreatic cancer von Doffo, Josefina, Bamopoulos, Stefanos A, Köse, Hazal, Orben, Felix, Zang, Chuanbing, Pons, Miriam, den Dekker, Alexander T, Brouwer, Rutger W W, Baluapuri, Apoorva, Habringer, Stefan, Reichert, Maximillian, Illendula, Anuradha, Krämer, Oliver H, Schick, Markus, Wolf, Elmar, van IJcken, Wilfred F J, Esposito, Irene, Keller, Ulrich, Schneider, Günter, Wirth, Matthias

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ID: 3526112 COMPARISON OF THE GENERATION OF PANCREATIC CANCER PATIENT-DERIVED ORGANOIDS BY ENDOSCOPIC ULTRASOUND-GUIDED FINE NEEDLE ASPIRATIONS AND FINE NEEDLE BIOPSIES von Wiessner, Johannes R., Orben, Felix, Schäfer, Arlett P., Fricke, Lisa, Herner, Alexander, Mayr, Ulrich, Phillip, Veit, Treiber, Matthias, von Figura, Guido, Abdelhafez, Mohamed, Schmid, Roland, Schneider, Günter, Schlag, Christoph, Reichert, Maximillian

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Abstract PO-070: Longitudinal precision oncology platform to identify chemotherapy-induced vulnerabilities in pancreatic cancer von Peschke, Katja, Jakubowski, Hannah, Schäfer, Arlett, Maurer, Carlo, Lange, Sebastian, Orben, Felix, Bernad, Raquel, Harder, Felix, Eiber, Matthias, Öllinger, Rupert, Schlitter, Melissa, Weichert, Wilko, Phillip, Veit, Schlag, Christoph, Schmid, Roland, Braren, Rickmer, Kong, Bo, Demir, Ekin, Friess, Helmut, Rad, Roland, Saur, Dieter, Schneider, Günter, Reichert, Maximilian

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Abstract 1793: Interaction of MYC and SUMOylation machinery in an aggressive pancreatic cancer subtype von Hassan, Zonera, Biederstädt, Alex, Schneeweis, Christian, Schick, Markus, Jonas, Nilsson, Wirth, Mathias, Coluccio, Andrea, Orben, Felix, Steiger, Katja, Slawska, Jolanta, Langston, Steve, Saur, Dieter, Rad, Roland, Reichert, Maximilian, Schneider, Guenter, Keller, Ulrich

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A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer von Lier, Svenja, Sellmer, Andreas, Orben, Felix, Heinzlmeir, Stephanie, Krauß, Lukas, Schneeweis, Christian, Hassan, Zonera, Schneider, Carolin, Patricia Gloria Schäfer, Arlett, Pongratz, Herwig, Engleitner, Thomas, Öllinger, Rupert, Kuisl, Anna, Bassermann, Florian, Schlag, Christoph, Kong, Bo, Dove, Stefan, Kuster, Bernhard, Rad, Roland, Reichert, Maximilian, Wirth, Matthias, Saur, Dieter, Mahboobi, Siavosh, Schneider, Günter

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Corrigendum to “A novel Cereblon E3 ligase modulator with antitumor activity in gastrointestinal cancer” [Bioorgan. Chem. 119 (2022) 105505] von Lier, Svenja, Sellmer, Andreas, Orben, Felix, Heinzlmeir, Stephanie, Krauß, Lukas, Schneeweis, Christian, Hassan, Zonera, Schneider, Carolin, Schäfer, Arlette, Pongratz, Herwig, Engleitner, Thomas, Öllinger, Rupert, Kuisl, Anna, Bassermann, Florian, Schlag, Christoph, Kong, Bo, Dove, Stefan, Kuster, Bernhard, Rad, Roland, Reichert, Maximilian, Wirth, Matthias, Saur, Dieter, Mahboobi, Siavosh, Schneider, Günter

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A Novel AMPK Inhibitor Sensitizes Pancreatic Cancer Cells to Ferroptosis Induction von Schneider, Carolin, Hilbert, Jorina, Genevaux, Franziska, Höfer, Stefanie, Krauß, Lukas, Schicktanz, Felix, Contreras, Constanza Tapia, Jansari, Shaishavi, Papargyriou, Aristeidis, Richter, Thorsten, Alfayomy, Abdallah M., Falcomatà, Chiara, Schneeweis, Christian, Orben, Felix, Öllinger, Ruppert, Wegwitz, Florian, Boshnakovska, Angela, Rehling, Peter, Müller, Denise, Ströbel, Philipp, Ellenrieder, Volker, Conradi, Lena, Hessmann, Elisabeth, Ghadimi, Michael, Grade, Marian, Wirth, Matthias, Steiger, Katja, Rad, Roland, Kuster, Bernhard, Sippl, Wolfgang, Reichert, Maximilian, Saur, Dieter, Schneider, Günter

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Human JAK1 gain of function causes dysregulated myelopoeisis and severe allergic inflammation von Biggs, Catherine M, Cordeiro-Santanach, Anna, Prykhozhij, Sergey V, Deveau, Adam P, Lin, Yi, Del Bel, Kate L, Orben, Felix, Ragotte, Robert J, Saferali, Aabida, Mostafavi, Sara, Dinh, Louie, Dai, Darlene, Weinacht, Katja G, Dobbs, Kerry, Ott de Bruin, Lisa, Sharma, Mehul, Tsai, Kevin, Priatel, John J, Schreiber, Richard A, Rozmus, Jacob, Hosking, Martin Ck, Shopsowitz, Kevin E, McKinnon, Margaret L, Vercauteren, Suzanne, Seear, Michael, Notarangelo, Luigi D, Lynn, Francis C, Berman, Jason N, Turvey, Stuart E

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