Organoid models of gastrointestinal cancers in basic and translational research von Lau, Harry Cheuk Hay, Kranenburg, Onno, Xiao, Haipeng, Yu, Jun

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Patient-derived organoids model cervical tissue dynamics and viral oncogenesis in cervical cancer von Lõhmussaar, Kadi, Oka, Rurika, Espejo Valle-Inclan, Jose, Smits, Milou H.H., Wardak, Hila, Korving, Jeroen, Begthel, Harry, Proost, Natalie, van de Ven, Marieke, Kranenburg, Onno W., Jonges, Trudy G.N., Zweemer, Ronald P., Veersema, Sebastiaan, van Boxtel, Ruben, Clevers, Hans

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Mouse and human urothelial cancer organoids: A tool for bladder cancer research von Mullenders, Jasper, de Jongh, Evelien, Brousali, Anneta, Roosen, Mieke, Blom, Jan P. A., Begthel, Harry, Korving, Jeroen, Jonges, Trudy, Kranenburg, Onno, Meijer, Richard, Clevers, Hans C.

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Patient-derived organoids as a predictive biomarker for treatment response in cancer patients von Wensink, G. Emerens, Elias, Sjoerd G., Mullenders, Jasper, Koopman, Miriam, Boj, Sylvia F., Kranenburg, Onno W., Roodhart, Jeanine M. L.

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Pancreatic cancer organoids recapitulate disease and allow personalized drug screening von Driehuis, Else, van Hoeck, Arne, Moore, Kat, Kolders, Sigrid, Francies, Hayley E., Gulersonmez, M. Can, Stigter, Edwin C. A., Burgering, Boudewijn, Geurts, Veerle, Gracanin, Ana, Bounova, Gergana, Morsink, Folkert H., Vries, Robert, Boj, Sylvia, van Es, Johan, Offerhaus, G. Johan A., Kranenburg, Onno, Garnett, Mathew J., Wessels, Lodewyk, Cuppen, Edwin, Brosens, Lodewijk A. A., Clevers, Hans

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Common anti-cancer therapies induce somatic mutations in stem cells of healthy tissue von Kuijk, Ewart, Kranenburg, Onno, Cuppen, Edwin, Van Hoeck, Arne

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Practical and Robust Identification of Molecular Subtypes in Colorectal Cancer by Immunohistochemistry von Trinh, Anne, Trumpi, Kari, De Sousa E Melo, Felipe, Wang, Xin, de Jong, Joan H, Fessler, Evelyn, Kuppen, Peter J K, Reimers, Marlies S, Swets, Marloes, Koopman, Miriam, Nagtegaal, Iris D, Jansen, Marnix, Hooijer, Gerrit K J, Offerhaus, George J A, Kranenburg, Onno, Punt, Cornelis J, Medema, Jan Paul, Markowetz, Florian, Vermeulen, Louis

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Colorectal Cancer-Infiltrating Regulatory T Cells: Functional Heterogeneity, Metabolic Adaptation, and Therapeutic Targeting von Aristin Revilla, Sonia, Kranenburg, Onno, Coffer, Paul J.

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Peritoneal Metastases From Colorectal Cancer: Defining and Addressing the Challenges von Kranenburg, Onno, van der Speeten, Kurt, de Hingh, Ignace

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Liver lymphatic drainage patterns follow segmental anatomy in a murine model von Frenkel, Nicola C., Poghosyan, Susanna, Verheem, André, Padera, Timothy P., Rinkes, Inne H. M. Borel, Kranenburg, Onno, Hagendoorn, Jeroen

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Ongoing chromosomal instability and karyotype evolution in human colorectal cancer organoids von Bolhaqueiro, Ana C. F., Ponsioen, Bas, Bakker, Bjorn, Klaasen, Sjoerd J., Kucukkose, Emre, van Jaarsveld, Richard H., Vivié, Judith, Verlaan-Klink, Ingrid, Hami, Nizar, Spierings, Diana C. J., Sasaki, Nobuo, Dutta, Devanjali, Boj, Sylvia F., Vries, Robert G. J., Lansdorp, Peter M., van de Wetering, Marc, van Oudenaarden, Alexander, Clevers, Hans, Kranenburg, Onno, Foijer, Floris, Snippert, Hugo J. G., Kops, Geert J. P. L.

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Phenotypic plasticity underlies local invasion and distant metastasis in colon cancer von Sacchetti, Andrea, Teeuwssen, Miriam, Verhagen, Mathijs, Joosten, Rosalie, Xu, Tong, Stabile, Roberto, van der Steen, Berdine, Watson, Martin M., Gusinac, Alem, Kim, Won Kyu, Ubink, Inge, Van de Werken, Harmen Jg, Fumagalli, Arianna, Paauwe, Madelon, Van Rheenen, Jacco, Sansom, Owen J., Kranenburg, Onno, Fodde, Riccardo

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Surgical implantation of an abdominal imaging window for intravital microscopy von Ritsma, Laila, Steller, Ernst J A, Ellenbroek, Saskia I J, Kranenburg, Onno, Borel Rinkes, Inne H M, van Rheenen, Jacco

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Distinct and overlapping functions of glutathione peroxidases 1 and 2 in limiting NF-κB-driven inflammation through redox-active mechanisms von Koeberle, Solveigh C., Gollowitzer, André, Laoukili, Jamila, Kranenburg, Onno, Werz, Oliver, Koeberle, Andreas, Kipp, Anna P.

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NOXA-dependent contextual synthetic lethality of BCL-XL inhibition and “osmotic reprogramming” in colorectal cancer von Knoll, Gertrud, Riffelsberger, Petra, Raats, Danielle, Kranenburg, Onno, Ehrenschwender, Martin

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ALDH1A1 expression is associated with poor differentiation, 'right-sidedness' and poor survival in human colorectal cancer von van der Waals, Lizet M, Borel Rinkes, Inne H M, Kranenburg, Onno

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Dose finding study for unilobar radioembolization using holmium-166 microspheres to improve resectability in patients with HCC: the RALLY protocol von Andel, Daan, Lam, Marnix G. E. H, de Bruijne, Joep, Smits, Maarten L. J, Braat, Arthur J. A. T, Moelker, Adriaan, Vegt, Erik, Ruiter, Simeon J. S, Noordzij, Walter, Grazi, Gianluca, Vallati, Giulio E, Bennink, Roel J, van Delden, Otto M, Kranenburg, Onno W, Ijzermans, Jan N. M, Nijkamp, Maarten W, Erdmann, Joris I, Sciuto, Rosa, Hagendoorn, Jeroen, Borel Rinkes, Inne H. M

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Co-cultures of colon cancer cells and cancer-associated fibroblasts recapitulate the aggressive features of mesenchymal-like colon cancer von Strating, Esther, Verhagen, Mathijs P, Wensink, Emerens, Dünnebach, Ester, Wijler, Liza, Aranguren, Itziar, De la Cruz, Alberto Sanchez, Peters, Niek A, Hageman, Joris H, van der Net, Mirjam M C, van Schelven, Susanne, Laoukili, Jamila, Fodde, Riccardo, Roodhart, Jeanine, Nierkens, Stefan, Snippert, Hugo, Gloerich, Martijn, Rinkes, Inne Borel, Elias, Sjoerd G, Kranenburg, Onno

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GPx2 suppression of H2O2 stress links the formation of differentiated tumor mass to metastatic capacity in colorectal cancer von Emmink, Benjamin L, Laoukili, Jamila, Kipp, Anna P, Koster, Jan, Govaert, Klaas M, Fatrai, Szabolcs, Verheem, Andre, Steller, Ernst J A, Brigelius-Flohé, Regina, Jimenez, Connie R, Borel Rinkes, Inne H M, Kranenburg, Onno

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KIT promotes tumor stroma formation and counteracts tumor-suppressive TGFβ signaling in colorectal cancer von Küçükköse, Emre, Peters, Niek A., Ubink, Inge, van Keulen, Veere A. M., Daghighian, Roxanna, Verheem, André, Laoukili, Jamila, Kranenburg, Onno

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