In Vivo Bioorthogonal Chemistry Enables Local Hydrogel and Systemic Pro-Drug To Treat Soft Tissue Sarcoma von Mejia Oneto, Jose M, Khan, Irfan, Seebald, Leah, Royzen, Maksim

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Bio-Orthogonal Chemistry and Reloadable Biomaterial Enable Local Activation of Antibiotic Prodrugs and Enhance Treatments against Staphylococcus aureus Infections von Czuban, Magdalena, Srinivasan, Sangeetha, Yee, Nathan A, Agustin, Edgar, Koliszak, Anna, Miller, Ethan, Khan, Irfan, Quinones, Ilenis, Noory, Hasina, Motola, Christopher, Volkmer, Rudolf, Di Luca, Mariagrazia, Trampuz, Andrej, Royzen, Maksim, Mejia Oneto, Jose M

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Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation von Wu, Kui, Yee, Nathan A, Srinivasan, Sangeetha, Mahmoodi, Amir, Zakharian, Michael, Mejia Oneto, Jose M, Royzen, Maksim

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Correction: Click activated protodrugs against cancer increase the therapeutic potential of chemotherapy through local capture and activation von Wu, Kui, Yee, Nathan A, Srinivasan, Sangeetha, Mahmoodi, Amir, Zakharian, Michael, Mejia Oneto, Jose M, Royzen, Maksim

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Titanium coating with mussel inspired polymer and bio-orthogonal chemistry enhances antimicrobial activity against Staphylococcus aureus von Czuban, Magdalena, Kulka, Michaël W., Wang, Lei, Koliszak, Anna, Achazi, Katharina, Schlaich, Christoph, Donskyi, Ievgen S., Di Luca, Mariagrazia, Mejia Oneto, Jose M., Royzen, Maksim, Haag, Rainer, Trampuz, Andrej

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Application of the Rh(II) Cyclization/Cycloaddition Cascade for the Total Synthesis of (±)-Aspidophytine von Mejía-Oneto, José M, Padwa, Albert

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Implantable biomaterial based on click chemistry for targeting small molecules von Mejía Oneto, José M., Gupta, Munish, Leach, J. Kent, Lee, Mark, Sutcliffe, Julie L.

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Total Synthesis of the Alkaloid (±)-Aspidophytine Based on Carbonyl Ylide Cycloaddition Chemistry von Mejía-Oneto, José M., Padwa, Albert

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Preparation of 2-diazo-2-oxopiperidin-3-yl-3-oxopropanoates. Useful reagents for Rh(II)-catalyzed cyclization-cycloaddition chemistry von Hong, Xuechuan, Mejía-Oneto, José M., France, Stefan, Padwa, Albert

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Longitudinal evaluation of cartilage repair tissue after microfracture using T2-mapping: a case report with arthroscopic and MRI correlation von Oneto, José M. Mejía, Ellermann, Jutta, LaPrade, Robert F.

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Click Chemistry Selectively Activates an Auristatin Protodrug with either Intratumoral or Systemic Tumor-Targeting Agents von McFarland, Jesse M., Alečković, Maša, Coricor, George, Srinivasan, Sangeetha, Tso, Matthew, Lee, John, Nguyen, Tri-Hung, Mejía Oneto, José M.

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Abstract 1347: The CAPAC Platform maximizes therapeutic benefit and reduces systemic cytotoxic exposure in small and large animals von Srinivasan, Sangeetha, Yee, Nathan A., Mahmoodi, Amir, Zakharian, Michael, Saville, M. Wayne, Oneto, Jose M. Mejia

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Abstract LB-002: SQ3370 enhances the safety of chemotherapeutics via local activation therapy von Yee, Nathan A., Srinivasan, Sangeetha, Royzen, Maksim, Oneto, Jose M. Mejia

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Abstract B43: Combining SQ3370, a doxorubicin-based therapeutic, with TLR and STING agonists enhances antitumor effects in murine tumor models von Aleckovic, Masa, Srinivasan, Sangeetha, McFarland, Jesse M, Priddy, Leslie, Tso, Matthew, Oneto, Jose M Mejia

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Abstract CT225: Phase 1 trial of SQ3370 in solid tumors von Guminski, Alexander, Wang, Ding, Bui, Nam, Bhadri, Vivek, De Silva, Madhawa, Steffner, Robert, Yee, Nathan A., Srinivasan, Sangeetha, Oneto, Jose M. Mejia, Saville, M. Wayne, Subbiah, Vivek

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Abstract A029: SQ3370: CAPAC platform enables tumor-localized therapy and minimizes systemic toxicities von Oneto, Jose M. Mejia, Srinivasan, Sangeetha, McFarland, Jesse M., Tso, Matthew, Aleckovic, Masa

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Cycloaddition Chemistry of 2-Vinyl-Substituted Indoles and Related Heteroaromatic Systems von Padwa, Albert, Lynch, Stephen M., Mejía-Oneto, José M., Zhang, Hongjun

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Abstract 4934: CAPAC: a modular platform that can improve the safety and efficacy of existing cancer therapies von Coricor, George, McFarland, Jesse M., Aleckovic, Masa, Srinivasan, Sangeetha, Lee, John, Priddy, Leslie, Tso, Matthew, Nguyen, Tri-Hung, Oneto, Jose M. Mejia

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Lewis acid-promoted α-hydroxy β-dicarbonyl to α-ketol ester rearrangement von Hong, Xuechuan, Mejía-Oneto, José M., Padwa, Albert

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Abstract CT177: SQ3370 in advanced solid tumors: Interim phase 1 results von Chawla, Sant P., Batty, Kathleen, Bhadri, Vivek, Bui, Nam, Guminski, Alexander D., Oneto, Jose M. Mejia, Srinivasan, Sangeetha, Strauss, James F., Subbiah, Vivek, Weiss, Mia C., Wilson, Rosalind, Yee, Nathan A., Zacharian, Michael, Kwatra, Vineet

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