Identification of Selective Inhibitors of Cancer Stem Cells by High-Throughput Screening von Gupta, Piyush B., Onder, Tamer T., Jiang, Guozhi, Tao, Kai, Kuperwasser, Charlotte, Weinberg, Robert A., Lander, Eric S.

Volltext

Enhanced elimination of oxidized guanine nucleotides inhibits oncogenic RAS-induced DNA damage and premature senescence von Rai, P, Young, J J, Burton, D G A, Giribaldi, M G, Onder, T T, Weinberg, R A

Volltext

Genome-wide Chromatin State Transitions Associated with Developmental and Environmental Cues von Zhu, Jiang, Adli, Mazhar, Zou, James Y., Verstappen, Griet, Coyne, Michael, Zhang, Xiaolan, Durham, Timothy, Miri, Mohammad, Deshpande, Vikram, De Jager, Philip L., Bennett, David A., Houmard, Joseph A., Muoio, Deborah M., Onder, Tamer T., Camahort, Ray, Cowan, Chad A., Meissner, Alexander, Epstein, Charles B., Shoresh, Noam, Bernstein, Bradley E.

Volltext

miR-9, a MYC/MYCN-activated microRNA, regulates E-cadherin and cancer metastasis von Ma, Li, Young, Jennifer, Prabhala, Harsha, Pan, Elizabeth, Mestdagh, Pieter, Muth, Daniel, Teruya-Feldstein, Julie, Reinhardt, Ferenc, Onder, Tamer T., Valastyan, Scott, Westermann, Frank, Speleman, Frank, Vandesompele, Jo, Weinberg, Robert A.

Volltext

Autocrine TGF-β and stromal cell-derived factor-1 (SDF-1) signaling drives the evolution of tumor-promoting mammary stromal myofibroblasts von Kojima, Yasushi, Acar, Ahmet, Eaton, Elinor Ng, Mellody, Kieran T, Scheel, Christina, Ben-Porath, Ittai, Onder, Tamer T, Wang, Zhigang C, Richardson, Andrea L, Weinberg, Robert A, Orimo, Akira

Volltext

Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways von Onder, Tamer T, Gupta, Piyush B, Mani, Sendurai A, Yang, Jing, Lander, Eric S, Weinberg, Robert A

Volltext

Chromatin-modifying enzymes as modulators of reprogramming von Onder, Tamer T., Kara, Nergis, Cherry, Anne, Sinha, Amit U., Zhu, Nan, Bernt, Kathrin M., Cahan, Patrick, Mancarci, B. Ogan, Unternaehrer, Juli, Gupta, Piyush B., Lander, Eric S., Armstrong, Scott A., Daley, George Q.

Volltext

Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes von Taube, Joseph H., Herschkowitz, Jason I., Komurov, Kakajan, Zhou, Alicia Y., Gupta, Supriya, Yang, Jing, Hartwell, Kimberly, Onder, Tamer T., Gupta, Piyush B., Evans, Kurt W., Hollier, Brett G., Ram, Prahlad T., Lander, Eric S., Rosen, Jeffrey M., Weinberg, Robert A., Mani, Sendurai A.

Volltext

Midbody accumulation through evasion of autophagy contributes to cellular reprogramming and tumorigenicity von Kuo, Tse-Chun, Chen, Chun-Ting, Baron, Desiree, Onder, Tamer T., Loewer, Sabine, Almeida, Sandra, Weismann, Cara M., Xu, Ping, Houghton, Jean-Marie, Gao, Fen-Biao, Daley, George Q., Doxsey, Stephen

Volltext

Overcoming chemoresistance in triple negative breast cancer by bromodomain inhibition von Yedier-Bayram, O., Cingoz, A., Aksu, A.C., Pinarbasi-Degirmenci, N., Esin, B., Kayabolen, A., Cevatemre, B., Acilan Ayhan, C., Philpott, M., Cribbs, A., Oppermann, U., Onder, T.T., Bagci Onder, T.

Volltext

Relationship between HER2-low status and efficacy of CDK4/6 inhibitors in advanced breast cancer: a real-world study von Önder, T., Ateş, Ö., Öner, İ., Karaçin, C.

Volltext

Development of a novel two-way 3D printed flexible spiral composite actuator based on shape memory alloy wire and its control von Önder, E T, Sümer, B, Başlamişli, S C

Volltext

Continuous Elimination of Oxidized Nucleotides Is Necessary to Prevent Rapid Onset of Cellular Senescence von Rai, Priyamvada, Onder, Tamer T., Young, Jennifer J., McFaline, Jose L., Pang, Bo, Dedon, Peter C., Weinberg, Robert A.

Volltext

Predicting survival after brain metastases in patients with bladder cancer von Önder, T., Karaçin, C., Kekilli, E., Göksel, F., Sertesen, E., Onur, İ. Deliktaş, Ateş, Ö., Yıldız, F., Arslan, Ü.Y

Volltext

EPIKOL, a chromatin-focused CRISPR/Cas9-based screening platform, to identify cancer-specific epigenetic vulnerabilities von Yedier-Bayram, Ozlem, Gokbayrak, Bengul, Kayabolen, Alisan, Aksu, Ali Cenk, Cavga, Ayse Derya, Cingöz, Ahmet, Kala, Ezgi Yagmur, Karabiyik, Goktug, Günsay, Rauf, Esin, Beril, Morova, Tunc, Uyulur, Fırat, Syed, Hamzah, Philpott, Martin, Cribbs, Adam P., Kung, Sonia H. Y., Lack, Nathan A., Onder, Tamer T., Bagci-Onder, Tugba

Volltext

Epigenetic-focused CRISPR/Cas9 screen identifies (absent, small, or homeotic)2-like protein (ASH2L) as a regulator of glioblastoma cell survival von Ozyerli-Goknar, Ezgi, Kala, Ezgi Yagmur, Aksu, Ali Cenk, Bulut, Ipek, Cingöz, Ahmet, Nizamuddin, Sheikh, Biniossek, Martin, Seker-Polat, Fidan, Morova, Tunc, Aztekin, Can, Kung, Sonia H. Y., Syed, Hamzah, Tuncbag, Nurcan, Gönen, Mehmet, Philpott, Martin, Cribbs, Adam P., Acilan, Ceyda, Lack, Nathan A., Onder, Tamer T., Timmers, H. T. Marc, Bagci-Onder, Tugba

Volltext

KDM2B, an H3K36-specific demethylase, regulates apoptotic response of GBM cells to TRAIL von Kurt, Ibrahim Cagri, Sur, Ilknur, Kaya, Ezgi, Cingoz, Ahmet, Kazancioglu, Selena, Kahya, Zeynep, Toparlak, Omer Duhan, Senbabaoglu, Filiz, Kaya, Zeynep, Ozyerli, Ezgi, Karahüseyinoglu, Sercin, Lack, Nathan A, Gümüs, Zeynep H, Onder, Tamer T, Bagci-Onder, Tugba

Volltext

Real-time imaging of the dynamics of death receptors and therapeutics that overcome TRAIL resistance in tumors von Bagci-Onder, T, Agarwal, A, Flusberg, D, Wanningen, S, Sorger, P, Shah, K

Volltext

Examining the role of chromatin modifying enzymes in medulloblastoma by utilizing a chemical library von Lokumcu, T, Senbabaoglu, F, Oppermann, U, Bagci-Onder, T

Volltext

414: Epigenetic modifications of androgen receptor signaling in castration resistant prostate cancer (CRPC) von Saraç, H, Toparlak, O.D, Kaplan, A, Ebrahimi, A, Bagci-Önder, T, Onder, T, Lack, N.A

Volltext