Differential effects of abaloparatide and teriparatide on hip cortical volumetric BMD by DXA-based 3D modeling von Winzenrieth, R., Ominsky, M.S., Wang, Y., Humbert, L., Weiss, R.J.

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Abaloparatide, a novel PTH receptor agonist, increased bone mass and strength in ovariectomized cynomolgus monkeys by increasing bone formation without increasing bone resorption von Doyle, N., Varela, A., Haile, S., Guldberg, R., Kostenuik, P. J., Ominsky, M. S., Smith, S. Y., Hattersley, G.

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Sclerostin and DKK1 Inhibition Preserves and Augments Alveolar Bone Volume and Architecture in Rats with Alveolar Bone Loss von Liu, M., Kurimoto, P., Zhang, J., Niu, Q.T., Stolina, M., Dechow, P.C., Feng, J.Q., Hesterman, J., Silva, M.D., Ominsky, M.S., Richards, W.G., Ke, H., Kostenuik, P.J.

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Adult Brtl/+ mouse model of osteogenesis imperfecta demonstrates anabolic response to sclerostin antibody treatment with increased bone mass and strength von Sinder, B. P., White, L. E., Salemi, J. D., Ominsky, M. S., Caird, M. S., Marini, J. C., Kozloff, K. M.

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Targeted Deletion of the Sclerostin Gene in Mice Results in Increased Bone Formation and Bone Strength von Li, Xiaodong, Ominsky, Michael S, Niu, Qing‐Tian, Sun, Ning, Daugherty, Betsy, D'Agostin, Diane, Kurahara, Carole, Gao, Yongming, Cao, Jin, Gong, Jianhua, Asuncion, Frank, Barrero, Mauricio, Warmington, Kelly, Dwyer, Denise, Stolina, Marina, Morony, Sean, Sarosi, Ildiko, Kostenuik, Paul J, Lacey, David L, Simonet, W Scott, Ke, Hua Zhu, Paszty, Chris

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The RANKL inhibitor OPG-Fc increases cortical and trabecular bone mass in young gonad-intact cynomolgus monkeys von OMINSKY, M. S, KOSTENUIK, P. J, CRANMER, P, SMITH, S. Y, ATKINSON, J. E

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Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice von Lloyd, S. A. J., Yuan, Y. Y., Kostenuik, P. J., Ominsky, M. S., Lau, A. G., Morony, S., Stolina, M., Asuncion, F. J., Bateman, Ted A.

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Skeletal deterioration induced by RANKL infusion: a model for high-turnover bone disease von Yuan, Y. Y., Kostenuik, P. J., Ominsky, M. S., Morony, S., Adamu, S., Simionescu, D. T., Basalyga, D. M., Asuncion, F. J., Bateman, T. A.

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THU0396 Six Months of Sclerostin Antibody Treatment in Cynomolgus Monkeys: Sustained Improvements in Vertebral Microarchitecture and Bone Strength Following a Temporal Increase in... von Ominsky, M. S., Samadfam, R., Jolette, J., Smith, S. Y., Ke, H. Z., Boyce, R.

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Sclerostin neutralizing monoclonal antibody decreases significantly the number of pelvic fractures and improves dramatically the size and interconnectivity of lumbar trabecular bon... von Chappard, D, Ammann, P, Ominsky, M, Behets, C, Devogelaer, J.-P, Manicourt, D.H

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Sclerostin antibody treatment enhances BMD and trabecular bone microarchitecture in male rats treated with glucocorticoids von Achiou, Z, Benaitreau, D, Pallu, S, Dolléans, E, Lespessailles, E, Ominsky, M, Benhamou, C.L

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THU0397 Increased Bone Mass and Bone Strength by Sclerostin Antibody (Scl-Ab) is Maintained by a RANKL Inhibitor in OVX Rats with Established Osteopenia von Ominsky, M., Li, X., Warmington, K., Niu, Q.-T., Asuncion, F., Dwyer, D., Grisanti, M., Han, C.-Y., Kostenuik, P., Stolina, M., Ke, H.

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Effects of anti-sclerostin antibody and running on bone remodeling and strength von Toumi, H, Benaitreau, D, Pallu, S, Mazor, M, Hambli, R, Ominsky, M, Lespessailles, E

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Bone Matrix Quality After Sclerostin Antibody Treatment von Ross, Ryan D, Edwards, Lindsey H, Acerbo, Alvin S, Ominsky, Michael S, Virdi, Amarjit S, Sena, Kotaro, Miller, Lisa M, Sumner, D Rick

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Soluble RANKL Induces High Bone Turnover and Decreases Bone Volume, Density, and Strength in Mice von Lloyd, S. A. J., Yuan, Y. Y., Kostenuik, P. J., Ominsky, M. S., Lau, A. G., Morony, S., Stolina, M., Asuncion, F. J., Bateman, Ted A.

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One Year of Transgenic Overexpression of Osteoprotegerin in Rats Suppressed Bone Resorption and Increased Vertebral Bone Volume, Density, and Strength von Ominsky, Michael S, Stolina, Marina, Li, Xiaodong, Corbin, Timothy J, Asuncion, Franklin J, Barrero, Mauricio, Niu, Qing‐Tian, Dwyer, Denise, Adamu, Steven, Warmington, Kelly S, Grisanti, Mario, Tan, Hong L, Ke, Hua Z, Simonet, William S, Kostenuik, Paul J

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Sclerostin Antibody Treatment Increases Bone Formation, Bone Mass, and Bone Strength in a Rat Model of Postmenopausal Osteoporosis von Li, Xiaodong, Ominsky, Michael S, Warmington, Kelly S, Morony, Sean, Gong, Jianhua, Cao, Jin, Gao, Yongming, Shalhoub, Victoria, Tipton, Barbara, Haldankar, Raj, Chen, Qing, Winters, Aaron, Boone, Tom, Geng, Zhaopo, Niu, Qing‐Tian, Ke, Hua Zhu, Kostenuik, Paul J, Simonet, W Scott, Lacey, David L, Paszty, Chris

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Sclerostin antibody improves skeletal parameters in a Brtl/+ mouse model of osteogenesis imperfecta von Sinder, Benjamin P, Eddy, Mary M, Ominsky, Michael S, Caird, Michelle S, Marini, Joan C, Kozloff, Kenneth M

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Dickkopf-1 is a master regulator of joint remodeling von Diarra, Danielle, Stolina, Marina, Polzer, Karin, Zwerina, Jochen, Ominsky, Michael S, Dwyer, Denise, Korb, Adelheid, Smolen, Josef, Hoffmann, Markus, Scheinecker, Clemens, van der Heide, Desiree, Landewe, Robert, Lacey, Dave, Richards, William G, Schett, Georg

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Inhibition of sclerostin by monoclonal antibody increases bone formation, bone mass, and bone strength in aged male rats von Li, Xiaodong, Warmington, Kelly S, Niu, Qing‐Tian, Asuncion, Franklin J, Barrero, Mauricio, Grisanti, Mario, Dwyer, Denise, Stouch, Brian, Thway, Theingi M, Stolina, Marina, Ominsky, Michael S, Kostenuik, Paul J, Simonet, William S, Paszty, Chris, Ke, Hua Zhu

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