Predicting Drug–Target Interactions Using Probabilistic Matrix Factorization von Cobanoglu, Murat Can, Liu, Chang, Hu, Feizhuo, Oltvai, Zoltán N, Bahar, Ivet

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Comparative Genome-Scale Metabolic Reconstruction and Flux Balance Analysis of Multiple Staphylococcus aureus Genomes Identify Novel Antimicrobial Drug Targets von Lee, Deok-Sun, Burd, Henry, Liu, Jiangxia, Almaas, Eivind, Wiest, Olaf, Barabási, Albert-László, Oltvai, Zoltán N, Kapatral, Vinayak

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Alterations in the omics profiles in mevalonate pathway-inhibited cancer cells von Warita, Tomoko, Irie, Nanami, Zhou, Yaxuan, Tashiro, Jiro, Sugiura, Akihiro, Oltvai, Zoltán N., Warita, Katsuhiko

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Network biology: understanding the cell's functional organization von Barabási, Albert-László, Oltvai, Zoltán N.

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Biomarker identification for statin sensitivity of cancer cell lines von Raghu, Vineet K., Beckwitt, Colin H., Warita, Katsuhiko, Wells, Alan, Benos, Panayiotis V., Oltvai, Zoltán N.

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Quantitative assessment of cell fate decision between autophagy and apoptosis von Liu, Bing, Oltvai, Zoltán N., Bayır, Hülya, Silverman, Gary A., Pak, Stephen C., Perlmutter, David H., Bahar, Ivet

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Functional and topological characterization of protein interaction networks von Yook, Soon-Hyung, Oltvai, Zoltán N., Barabási, Albert-László

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Concomitant attenuation of HMGCR expression and activity enhances the growth inhibitory effect of atorvastatin on TGF-β-treated epithelial cancer cells von Warita, Katsuhiko, Ishikawa, Takuro, Sugiura, Akihiro, Tashiro, Jiro, Shimakura, Hiroaki, Hosaka, Yoshinao Z., Ohta, Ken-ichi, Warita, Tomoko, Oltvai, Zoltán N.

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A semi-supervised method for predicting transcription factor-gene interactions in Escherichia coli von Ernst, Jason, Beg, Qasim K, Kay, Krin A, Balázsi, Gábor, Oltvai, Zoltán N, Bar-Joseph, Ziv

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Significance of p53 dynamics in regulating apoptosis in response to ionizing radiation and polypharmacological strategies von Liu, Bing, Bhatt, Divesh, Oltvai, Zoltán N., Greenberger, Joel S., Bahar, Ivet

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Identifying ligand binding conformations of the β2-adrenergic receptor by using its agonists as computational probes von Isin, Basak, Estiu, Guillermina, Wiest, Olaf, Oltvai, Zoltán N

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Shift from stochastic to spatially-ordered expression of serine-glycine synthesis enzymes in 3D microtumors von Singh, Manjulata, Warita, Katsuhiko, Warita, Tomoko, Faeder, James R., Lee, Robin E. C., Sant, Shilpa, Oltvai, Zoltán N.

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Repurposing of the Cardiovascular Drug Statin for the Treatment of Cancers: Efficacy of Statin-Dipyridamole Combination Treatment in Melanoma Cell Lines von Irie, Nanami, Mizoguchi, Kana, Warita, Tomoko, Nakano, Mirai, Sasaki, Kasuga, Tashiro, Jiro, Osaki, Tomohiro, Ishikawa, Takuro, Oltvai, Zoltán N, Warita, Katsuhiko

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Statin drugs to reduce breast cancer recurrence and mortality von Beckwitt, Colin H, Brufsky, Adam, Oltvai, Zoltán N, Wells, Alan

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Expression of housekeeping genes varies depending on mevalonate pathway inhibition in cancer cells von Irie, Nanami, Warita, Katsuhiko, Tashiro, Jiro, Zhou, Yaxuan, Ishikawa, Takuro, Oltvai, Zoltán N., Warita, Tomoko

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Aggregation of topological motifs in the Escherichia coli transcriptional regulatory network von Dobrin, Radu, Beg, Qasim K, Barabási, Albert-László, Oltvai, Zoltán N

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Assessing acquired resistance to IDH1 inhibitor therapy by full-exon IDH1 sequencing and structural modeling von Oltvai, Zoltán N, Harley, Susan E, Koes, David, Michel, Stephen, Warlick, Erica D, Nelson, Andrew C, Yohe, Sophia, Mroz, Pawel

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Rhapsody: predicting the pathogenicity of human missense variants von Ponzoni, Luca, Peñaherrera, Daniel A, Oltvai, Zoltán N, Bahar, Ivet

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Impact of the solvent capacity constraint on E. coli metabolism von Vazquez, Alexei, Beg, Qasim K, Demenezes, Marcio A, Ernst, Jason, Bar-Joseph, Ziv, Barabási, Albert-László, Boros, László G, Oltvai, Zoltán N

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Statins attenuate outgrowth of breast cancer metastases von Beckwitt, Colin H., Clark, Amanda M., Ma, Bo, Whaley, Diana, Oltvai, Zoltán N., Wells, Alan

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