Dynamics of genomic clones in breast cancer patient xenografts at single-cell resolution von Eirew, Peter, Steif, Adi, Khattra, Jaswinder, Ha, Gavin, Yap, Damian, Farahani, Hossein, Gelmon, Karen, Chia, Stephen, Mar, Colin, Wan, Adrian, Laks, Emma, Biele, Justina, Shumansky, Karey, Rosner, Jamie, McPherson, Andrew, Nielsen, Cydney, Roth, Andrew J. L., Lefebvre, Calvin, Bashashati, Ali, de Souza, Camila, Siu, Celia, Aniba, Radhouane, Brimhall, Jazmine, Oloumi, Arusha, Osako, Tomo, Bruna, Alejandra, Sandoval, Jose L., Algara, Teresa, Greenwood, Wendy, Leung, Kaston, Cheng, Hongwei, Xue, Hui, Wang, Yuzhuo, Lin, Dong, Mungall, Andrew J., Moore, Richard, Zhao, Yongjun, Lorette, Julie, Nguyen, Long, Huntsman, David, Eaves, Connie J., Hansen, Carl, Marra, Marco A., Caldas, Carlos, Shah, Sohrab P., Aparicio, Samuel

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Targeting Tumor Hypoxia: Suppression of Breast Tumor Growth and Metastasis by Novel Carbonic Anhydrase IX Inhibitors von YUANMEI LOU, MCDONALD, Paul C, CLARKE, Blaise, SUTHERLAND, Brent W, WATERHOUSE, Dawn, BALLY, Marcel, ROSKELLEY, Calvin, OVERALL, Christopher M, MINCHINTON, Andrew, PACCHIANO, Fabio, CARTA, Fabrizio, SCOZZAFAVA, Andrea, OLOUMI, Arusha, TOUISNI, Nadia, WINUM, Jean-Yves, SUPURAN, Claudiu T, DEDHAR, Shoukat, CHIA, Stephen, OSTLUND, Christina, AHMADI, Ardalan, KYLE, Alastair, AUF DEM KELLER, Ulrich, LEUNG, Samuel, HUNTSMAN, David

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CDK12 regulates alternative last exon mRNA splicing and promotes breast cancer cell invasion von Tien, Jerry F, Mazloomian, Alborz, Cheng, S-W Grace, Hughes, Christopher S, Chow, Christalle C T, Canapi, Leanna T, Oloumi, Arusha, Trigo-Gonzalez, Genny, Bashashati, Ali, Xu, James, Chang, Vicky C-D, Shah, Sohrab P, Aparicio, Samuel, Morin, Gregg B

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Integrative analysis of genome-wide loss of heterozygosity and monoallelic expression at nucleotide resolution reveals disrupted pathways in triple-negative breast cancer von Ha, Gavin, Roth, Andrew, Lai, Daniel, Bashashati, Ali, Ding, Jiarui, Goya, Rodrigo, Giuliany, Ryan, Rosner, Jamie, Oloumi, Arusha, Shumansky, Karey, Chin, Suet-Feung, Turashvili, Gulisa, Hirst, Martin, Caldas, Carlos, Marra, Marco A, Aparicio, Samuel, Shah, Sohrab P

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Rictor and Integrin-Linked Kinase Interact and Regulate Akt Phosphorylation and Cancer Cell Survival von MCDONALD, Paul C, OLOUMI, Arusha, MILLS, Julia, DOBREVA, Iveta, MAIDAN, Mykola, GRAY, Virginia, WEDERELL, Elizabeth D, BALLY, Marcel B, FOSTER, Leonard J, DEDHAR, Shoukat

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CLK-dependent exon recognition and conjoined gene formation revealed with a novel small molecule inhibitor von Funnell, Tyler, Tasaki, Shinya, Oloumi, Arusha, Araki, Shinsuke, Kong, Esther, Yap, Damian, Nakayama, Yusuke, Hughes, Christopher S., Cheng, S.-W. Grace, Tozaki, Hirokazu, Iwatani, Misa, Sasaki, Satoshi, Ohashi, Tomohiro, Miyazaki, Tohru, Morishita, Nao, Morishita, Daisuke, Ogasawara-Shimizu, Mari, Ohori, Momoko, Nakao, Shoichi, Karashima, Masatoshi, Sano, Masaya, Murai, Aiko, Nomura, Toshiyuki, Uchiyama, Noriko, Kawamoto, Tomohiro, Hara, Ryujiro, Nakanishi, Osamu, Shumansky, Karey, Rosner, Jamie, Wan, Adrian, McKinney, Steven, Morin, Gregg B., Nakanishi, Atsushi, Shah, Sohrab, Toyoshiba, Hiroyoshi, Aparicio, Samuel

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Integrin‐linked kinase regulates E‐cadherin expression through PARP‐1 von McPhee, Timothy R., McDonald, Paul C., Oloumi, Arusha, Dedhar, Shoukat

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Erratum: The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes von Pereira, Bernard, Chin, Suet-Feung, Rueda, Oscar M., Vollan, Hans-Kristian Moen, Provenzano, Elena, Bardwell, Helen A., Pugh, Michelle, Jones, Linda, Russell, Roslin, Sammut, Stephen-John, Tsui, Dana W. Y., Liu, Bin, Dawson, Sarah-Jane, Abraham, Jean, Northen, Helen, Peden, John F., Mukherjee, Abhik, Turashvili, Gulisa, Green, Andrew R., McKinney, Steve, Oloumi, Arusha, Shah, Sohrab, Rosenfeld, Nitzan, Murphy, Leigh, Bentley, David R., Ellis, Ian O., Purushotham, Arnie, Pinder, Sarah E., Børresen-Dale, Anne-Lise, Earl, Helena M., Pharoah, Paul D., Ross, Mark T., Aparicio, Samuel, Caldas, Carlos

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The somatic mutation profiles of 2,433 breast cancers refine their genomic and transcriptomic landscapes von Pereira, Bernard, Chin, Suet-Feung, Rueda, Oscar M., Vollan, Hans-Kristian Moen, Provenzano, Elena, Bardwell, Helen A., Pugh, Michelle, Jones, Linda, Russell, Roslin, Sammut, Stephen-John, Tsui, Dana W. Y., Liu, Bin, Dawson, Sarah-Jane, Abraham, Jean, Northen, Helen, Peden, John F., Mukherjee, Abhik, Turashvili, Gulisa, Green, Andrew R., McKinney, Steve, Oloumi, Arusha, Shah, Sohrab, Rosenfeld, Nitzan, Murphy, Leigh, Bentley, David R., Ellis, Ian O., Purushotham, Arnie, Pinder, Sarah E., Børresen-Dale, Anne-Lise, Earl, Helena M., Pharoah, Paul D., Ross, Mark T., Aparicio, Samuel, Caldas, Carlos

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Mutation discovery in regions of segmental cancer genome amplifications with CoNAn-SNV: a mixture model for next generation sequencing of tumors von Crisan, Anamaria, Goya, Rodrigo, Ha, Gavin, Ding, Jiarui, Prentice, Leah M, Oloumi, Arusha, Senz, Janine, Zeng, Thomas, Tse, Kane, Delaney, Allen, Marra, Marco A, Huntsman, David G, Hirst, Martin, Aparicio, Sam, Shah, Sohrab

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Critical Role of Integrin-Linked Kinase in Granule Cell Precursor Proliferation and Cerebellar Development von Mills, Julia, Niewmierzycka, Agnieszka, Oloumi, Arusha, Rico, Beatriz, St-Arnaud, Rene, Mackenzie, Ian R, Mawji, Nasrin M, Wilson, Jason, Reichardt, Louis F, Dedhar, Shoukat

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The somatic mutation profiles of 2,433 breast cancers refines their genomic and transcriptomic landscapes von Pereira, Bernard, Chin, Suet-Feung, Rueda, Oscar M, Vollan, Hans-Kristian Moen, Provenzano, Elena, Bardwell, Helen A, Pugh, Michelle, Jones, Linda, Russell, Roslin, Sammut, Stephen-John, Tsui, Dana W Y, Liu, Bin, Dawson, Sarah-Jane, Abraham, Jean, Northen, Helen, Peden, John F, Mukherjee, Abhik, Turashvili, Gulisa, Green, Andrew R, McKinney, Steve, Oloumi, Arusha, Shah, Sohrab, Rosenfeld, Nitzan, Murphy, Leigh, Bentley, David R, Ellis, Ian O, Purushotham, Arnie, Pinder, Sarah E, Børresen-Dale, Anne-Lise, Earl, Helena M, Pharoah, Paul D, Ross, Mark T, Aparicio, Samuel, Caldas, Carlos

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The clonal and mutational evolution spectrum of primary triple-negative breast cancers von Shah, Sohrab P., Roth, Andrew, Goya, Rodrigo, Oloumi, Arusha, Ha, Gavin, Zhao, Yongjun, Turashvili, Gulisa, Ding, Jiarui, Tse, Kane, Haffari, Gholamreza, Bashashati, Ali, Prentice, Leah M., Khattra, Jaswinder, Burleigh, Angela, Yap, Damian, Bernard, Virginie, McPherson, Andrew, Shumansky, Karey, Crisan, Anamaria, Giuliany, Ryan, Heravi-Moussavi, Alireza, Rosner, Jamie, Lai, Daniel, Birol, Inanc, Varhol, Richard, Tam, Angela, Dhalla, Noreen, Zeng, Thomas, Ma, Kevin, Chan, Simon K., Griffith, Malachi, Moradian, Annie, Cheng, S.-W. Grace, Morin, Gregg B., Watson, Peter, Gelmon, Karen, Chia, Stephen, Chin, Suet-Feung, Curtis, Christina, Rueda, Oscar M., Pharoah, Paul D., Damaraju, Sambasivarao, Mackey, John, Hoon, Kelly, Harkins, Timothy, Tadigotla, Vasisht, Sigaroudinia, Mahvash, Gascard, Philippe, Tlsty, Thea, Costello, Joseph F., Meyer, Irmtraud M., Eaves, Connie J., Wasserman, Wyeth W., Jones, Steven, Huntsman, David, Hirst, Martin, Caldas, Carlos, Marra, Marco A., Aparicio, Samuel

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Ordering of mutations in preinvasive disease stages of esophageal carcinogenesis von Weaver, Jamie M J, Ross-Innes, Caryn S, Shannon, Nicholas, Lynch, Andy G, Forshew, Tim, Barbera, Mariagnese, Murtaza, Muhammed, Ong, Chin-Ann J, Lao-Sirieix, Pierre, Dunning, Mark J, Smith, Laura, Smith, Mike L, Anderson, Charlotte L, Carvalho, Benilton, O'Donovan, Maria, Underwood, Timothy J, May, Andrew P, Grehan, Nicola, Hardwick, Richard, Davies, Jim, Oloumi, Arusha, Aparicio, Sam, Caldas, Carlos, Eldridge, Matthew D, Edwards, Paul A W, Rosenfeld, Nitzan, Tavaré, Simon, Fitzgerald, Rebecca C

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ARID1A Mutations in Endometriosis-Associated Ovarian Carcinomas von Wiegand, Kimberly C, Shah, Sohrab P, Al-Agha, Osama M, Zhao, Yongjun, Tse, Kane, Zeng, Thomas, Senz, Janine, McConechy, Melissa K, Anglesio, Michael S, Kalloger, Steve E, Yang, Winnie, Heravi-Moussavi, Alireza, Giuliany, Ryan, Chow, Christine, Fee, John, Zayed, Abdalnasser, Prentice, Leah, Melnyk, Nataliya, Turashvili, Gulisa, Delaney, Allen D, Madore, Jason, Yip, Stephen, McPherson, Andrew W, Ha, Gavin, Bell, Lynda, Fereday, Sian, Tam, Angela, Galletta, Laura, Tonin, Patricia N, Provencher, Diane, Miller, Dianne, Jones, Steven J.M, Moore, Richard A, Morin, Gregg B, Oloumi, Arusha, Boyd, Niki, Aparicio, Samuel A, Shih, Ie-Ming, Mes-Masson, Anne-Marie, Bowtell, David D, Hirst, Martin, Gilks, Blake, Marra, Marco A, Huntsman, David G

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JointSNVMix: a probabilistic model for accurate detection of somatic mutations in normal/tumour paired next-generation sequencing data von ROTH, Andrew, JIARUI DING, MARRA, Marco A, APARICIO, Samuel, SHAH, SohrabP, MORIN, Ryan, CRISAN, Anamaria, HA, Gavin, GIULIANY, Ryan, BASHASHATI, Ali, HIRST, Martin, TURASHVILI, Gulisa, OLOUMI, Arusha

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Feature-based classifiers for somatic mutation detection in tumour-normal paired sequencing data von Ding, Jiarui, Bashashati, Ali, Roth, Andrew, Oloumi, Arusha, Tse, Kane, Zeng, Thomas, Haffari, Gholamreza, Hirst, Martin, Marra, Marco A., Condon, Anne, Aparicio, Samuel, Shah, Sohrab P.

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Regulation of E-cadherin expression and β-catenin/Tcf transcriptional activity by the integrin-linked kinase von Oloumi, Arusha, McPhee, Timothy, Dedhar, Shoukat

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Integrin-linked kinase as a target for ERG-mediated invasive properties in prostate cancer models von BECKER-SANTOS, Daiana D, YUBIN GUO, DEDHAR, Shoukat, COX, Michael E, GHAFFARI, Mazyar, VICKERS, Elaine D, LEHMAN, Melanie, ALTAMIRANO-DIMAS, Manuel, OLOUMI, Arusha, FURUKAWA, Junya, SHARMA, Manju, YUZHUO WANG

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Using next-generation sequencing for the diagnosis of rare disorders: a family with retinitis pigmentosa and skeletal abnormalities von Schrader, Kasmintan A, Heravi-Moussavi, Alireza, Waters, Paula J, Senz, Janine, Whelan, James, Ha, Gavin, Eydoux, Patrice, Nielsen, Torsten, Gallagher, Barry, Oloumi, Arusha, Boyd, Niki, Fernandez, Bridget A, Young, Terry-Lynn, Jones, Steven JM, Hirst, Martin, Shah, Sohrab P, Marra, Marco A, Green, Jane, Huntsman, David G

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