Serine synthesis pathway inhibition cooperates with dietary serine and glycine limitation for cancer therapy von Tajan, Mylène, Hennequart, Marc, Cheung, Eric C., Zani, Fabio, Hock, Andreas K., Legrave, Nathalie, Maddocks, Oliver D. K., Ridgway, Rachel A., Athineos, Dimitris, Suárez-Bonnet, Alejandro, Ludwig, Robert L., Novellasdemunt, Laura, Angelis, Nikolaos, Li, Vivian S. W., Vlachogiannis, Georgios, Valeri, Nicola, Mainolfi, Nello, Suri, Vipin, Friedman, Adam, Manfredi, Mark, Blyth, Karen, Sansom, Owen J., Vousden, Karen H.

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Metabolic regulation by p53 von Maddocks, Oliver D. K., Vousden, Karen H.

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Serine is a natural ligand and allosteric activator of pyruvate kinase M2 von Chaneton, Barbara, Hillmann, Petra, Zheng, Liang, Martin, Agnès C. L., Maddocks, Oliver D. K., Chokkathukalam, Achuthanunni, Coyle, Joseph E., Jankevics, Andris, Holding, Finn P., Vousden, Karen H., Frezza, Christian, O’Reilly, Marc, Gottlieb, Eyal

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Metabolic cross-feeding in imbalanced diets allows gut microbes to improve reproduction and alter host behaviour von Henriques, Sílvia F., Dhakan, Darshan B., Serra, Lúcia, Francisco, Ana Patrícia, Carvalho-Santos, Zita, Baltazar, Célia, Elias, Ana Paula, Anjos, Margarida, Zhang, Tong, Maddocks, Oliver D. K., Ribeiro, Carlos

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Serine and Functional Metabolites in Cancer von Newman, Alice C, Maddocks, Oliver D.K

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Serine starvation induces stress and p53-dependent metabolic remodelling in cancer cells von Maddocks, Oliver D. K., Berkers, Celia R., Mason, Susan M., Zheng, Liang, Blyth, Karen, Gottlieb, Eyal, Vousden, Karen H.

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The KRAS-BCAA-BCAT2 axis in PDAC development von Falcone, Mattia, Maddocks, Oliver D. K.

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Sensitisation of cancer cells to radiotherapy by serine and glycine starvation von Falcone, Mattia, Uribe, Alejandro Huerta, Papalazarou, Vasileios, Newman, Alice C., Athineos, Dimitris, Stevenson, Katrina, Sauvé, Charles-Etienne Gabriel, Gao, Yajing, Kim, Jin K., Del Latto, Michael, Kierstead, Maria, Wu, Chao, Smith, J. Joshua, Romesser, Paul B., Chalmers, Anthony J., Blyth, Karen, Maddocks, Oliver D. K.

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Attaching and effacing Escherichia coli downregulate DNA mismatch repair protein in vitro and are associated with colorectal adenocarcinomas in humans von Maddocks, Oliver D K, Short, Abigail J, Donnenberg, Michael S, Bader, Scott, Harrison, David J

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Targeting the autophagy-NAD axis protects against cell death in Niemann-Pick type C1 disease models von Kataura, Tetsushi, Sedlackova, Lucia, Sun, Congxin, Kocak, Gamze, Wilson, Niall, Banks, Peter, Hayat, Faisal, Trushin, Sergey, Trushina, Eugenia, Maddocks, Oliver D. K., Oblong, John E., Miwa, Satomi, Imoto, Masaya, Saiki, Shinji, Erskine, Daniel, Migaud, Marie E., Sarkar, Sovan, Korolchuk, Viktor I.

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The creatine–phosphagen system is mechanoresponsive in pancreatic adenocarcinoma and fuels invasion and metastasis von Papalazarou, Vassilis, Zhang, Tong, Paul, Nikki R., Juin, Amelie, Cantini, Marco, Maddocks, Oliver D. K., Salmeron-Sanchez, Manuel, Machesky, Laura M.

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Mechanistic insights into p53‐regulated cytotoxicity of combined entinostat and irinotecan against colorectal cancer cells von Marx, Christian, Sonnemann, Jürgen, Beyer, Mandy, Maddocks, Oliver D. K., Lilla, Sergio, Hauzenberger, Irene, Piée‐Staffa, Andrea, Siniuk, Kanstantsin, Nunna, Suneetha, Marx‐Blümel, Lisa, Westermann, Martin, Wagner, Tobias, Meyer, Felix B., Thierbach, René, Mullins, Christina S., Kdimati, Said, Linnebacher, Michael, Neri, Francesco, Heinzel, Thorsten, Wang, Zhao‐Qi, Krämer, Oliver H.

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Persistent mTORC1 signaling in cell senescence results from defects in amino acid and growth factor sensing von Carroll, Bernadette, Nelson, Glyn, Rabanal-Ruiz, Yoana, Kucheryavenko, Olena, Dunhill-Turner, Natasha A, Chesterman, Charlotte C, Zahari, Qabil, Zhang, Tong, Conduit, Sarah E, Mitchell, Christina A, Maddocks, Oliver D K, Lovat, Penny, von Zglinicki, Thomas, Korolchuk, Viktor I

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mTORC1 activity is supported by spatial association with focal adhesions von Rabanal-Ruiz, Yoana, Byron, Adam, Wirth, Alexander, Madsen, Ralitsa, Sedlackova, Lucia, Hewitt, Graeme, Nelson, Glyn, Stingele, Julian, Wills, Jimi C., Zhang, Tong, Zeug, Andre, Faessler, Reinhard, Vanhaesebroeck, Bart, Maddocks, Oliver D. K., Ponimaskin, Evgeni, Carroll, Bernadette, Korolchuk, Viktor

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One-carbon metabolism in cancer von Newman, Alice C, Maddocks, Oliver D K

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Global metabolic alterations in colorectal cancer cells during irinotecan-induced DNA replication stress von Marx, Christian, Sonnemann, Jürgen, Maddocks, Oliver D K, Marx-Blümel, Lisa, Beyer, Mandy, Hoelzer, Doerte, Thierbach, René, Maletzki, Claudia, Linnebacher, Michael, Heinzel, Thorsten, Krämer, Oliver H

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p53-mediated adaptation to serine starvation is retained by a common tumour-derived mutant von Humpton, Timothy J, Hock, Andreas K, Maddocks, Oliver D K, Vousden, Karen H

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PHD1 regulates p53‐mediated colorectal cancer chemoresistance von Deschoemaeker, Sofie, Di Conza, Giusy, Lilla, Sergio, Martín‐Pérez, Rosa, Mennerich, Daniela, Boon, Lise, Hendrikx, Stefanie, Maddocks, Oliver DK, Marx, Christian, Radhakrishnan, Praveen, Prenen, Hans, Schneider, Martin, Myllyharju, Johanna, Kietzmann, Thomas, Vousden, Karen H, Zanivan, Sara, Mazzone, Massimiliano

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Serine Metabolism Supports the Methionine Cycle and DNA/RNA Methylation through De Novo ATP Synthesis in Cancer Cells von Maddocks, Oliver D.K., Labuschagne, Christiaan F., Adams, Peter D., Vousden, Karen H.

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Control of TSC2-Rheb signaling axis by arginine regulates mTORC1 activity von Carroll, Bernadette, Maetzel, Dorothea, Maddocks, Oliver Dk, Otten, Gisela, Ratcliff, Matthew, Smith, Graham R, Dunlop, Elaine A, Passos, João F, Davies, Owen R, Jaenisch, Rudolf, Tee, Andrew R, Sarkar, Sovan, Korolchuk, Viktor I

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