Modulation of astrocyte reactivity improves functional deficits in mouse models of Alzheimer's disease von Ceyzériat, Kelly, Ben Haim, Lucile, Denizot, Audrey, Pommier, Dylan, Matos, Marco, Guillemaud, Océane, Palomares, Marie-Ange, Abjean, Laurene, Petit, Fanny, Gipchtein, Pauline, Gaillard, Marie-Claude, Guillermier, Martine, Bernier, Sueva, Gaudin, Mylène, Aurégan, Gwenaëlle, Joséphine, Charlène, Déchamps, Nathalie, Veran, Julien, Langlais, Valentin, Cambon, Karine, Bemelmans, Alexis P, Baijer, Jan, Bonvento, Gilles, Dhenain, Marc, Deleuze, Jean-François, Oliet, Stéphane H R, Brouillet, Emmanuel, Hantraye, Philippe, Carrillo-de Sauvage, Maria-Angeles, Olaso, Robert, Panatier, Aude, Escartin, Carole

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Systematic analysis of TruSeq, SMARTer and SMARTer Ultra-Low RNA-seq kits for standard, low and ultra-low quantity samples von Palomares, Marie-Ange, Dalmasso, Cyril, Bonnet, Eric, Derbois, Céline, Brohard-Julien, Solène, Ambroise, Christophe, Battail, Christophe, Deleuze, Jean-François, Olaso, Robert

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POLR1B and neural crest cell anomalies in Treacher Collins syndrome type 4 von Sanchez, Elodie, Laplace-Builhé, Béryl, Mau-Them, Frédéric Tran, Richard, Eric, Goldenberg, Alice, Toler, Tomi L., Guignard, Thomas, Gatinois, Vincent, Vincent, Marie, Blanchet, Catherine, Boland, Anne, Bihoreau, Marie Thérèse, Deleuze, Jean-Francois, Olaso, Robert, Nephi, Walton, Lüdecke, Hermann-Josef, Verheij, Joke, Moreau-Lenoir, Florence, Denoyelle, Françoise, Rivière, Jean-Baptiste, Laplanche, Jean-Louis, Willing, Marcia, Captier, Guillaume, Apparailly, Florence, Wieczorek, Dagmar, Collet, Corinne, Djouad, Farida, Geneviève, David

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A novel nonsense variant in SUPT20H gene associated with Rheumatoid Arthritis identified by Whole Exome Sequencing of multiplex families von Veyssiere, Maëva, Perea, Javier, Michou, Laetitia, Boland, Anne, Caloustian, Christophe, Olaso, Robert, Deleuze, Jean-François, Cornelis, François, Petit-Teixeira, Elisabeth, Chaudru, Valérie

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Investigation of candidate gene copy number identifies FCGR3B as a potential biomarker for rheumatoid arthritis von Ben Kilani, Mohamed Sahbi, Cornelis, François, Olaso, Robert E, Chaudru, Valérie, Petit-Teixeira, Elisabeth

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A large‐scale exome array analysis of venous thromboembolism von Lindström, Sara, Brody, Jennifer A., Turman, Constance, Germain, Marine, Bartz, Traci M., Smith, Erin N., Chen, Ming‐Huei, Puurunen, Marja, Chasman, Daniel, Hassler, Jeffrey, Pankratz, Nathan, Basu, Saonli, Guan, Weihua, Gyorgy, Beata, Ibrahim, Manal, Empana, Jean‐Philippe, Olaso, Robert, Jackson, Rebecca, Brækkan, Sigrid K., McKnight, Barbara, Deleuze, Jean‐Francois, O’Donnell, Cristopher J., Jouven, Xavier, Frazer, Kelly A., Psaty, Bruce M., Wiggins, Kerri L., Taylor, Kent, Reiner, Alexander P., Heckbert, Susan R., Kooperberg, Charles, Ridker, Paul, Hansen, John‐Bjarne, Tang, Weihong, Johnson, Andrew D., Morange, Pierre‐Emmanuel, Trégouët, David A., Kraft, Peter, Smith, Nicholas L., Kabrhel, Christopher

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Rare genetic susceptibility variants assessment in autism spectrum disorder: detection rate and practical use von Husson, Thomas, Lecoquierre, François, Cassinari, Kevin, Charbonnier, Camille, Quenez, Olivier, Goldenberg, Alice, Guerrot, Anne-Marie, Richard, Anne-Claire, Drouin-Garraud, Valérie, Brehin, Anne-Claire, Soleimani, Maryam, Taton, Romain, Rotharmel, Maud, Rosier, Antoine, Chambon, Pascal, Le Meur, Nathalie, Joly-Helas, Géraldine, Saugier-Veber, Pascale, Boland, Anne, Deleuze, Jean-François, Olaso, Robert, Frebourg, Thierry, Nicolas, Gael, Guillin, Olivier, Campion, Dominique

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Differentially expressed genes in autosomal dominant osteopetrosis type II osteoclasts reveal known and novel pathways for osteoclast biology von Coudert, Amélie E, Del Fattore, Andrea, Baulard, Céline, Olaso, Robert, Schiltz, Corinne, Collet, Corinne, Teti, Anna, de Vernejoul, Marie-Christine

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Genome sequencing in cytogenetics: Comparison of short‐read and linked‐read approaches for germline structural variant detection and characterization von Uguen, Kévin, Jubin, Claire, Duffourd, Yannis, Bardel, Claire, Malan, Valérie, Dupont, Jean‐Michel, El Khattabi, Laila, Chatron, Nicolas, Vitobello, Antonio, Rollat‐Farnier, Pierre‐Antoine, Baulard, Céline, Lelorch, Marc, Leduc, Aurélie, Tisserant, Emilie, Tran Mau‐Them, Frédéric, Danjean, Vincent, Delepine, Marc, Till, Marianne, Meyer, Vincent, Lyonnet, Stanislas, Mosca‐Boidron, Anne‐laure, Thevenon, Julien, Faivre, Laurence, Thauvin‐Robinet, Christel, Schluth‐Bolard, Caroline, Boland, Anne, Olaso, Robert, Callier, Patrick, Romana, Serge, Deleuze, Jean‐François, Sanlaville, Damien

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Familial breast cancer and DNA repair genes: Insights into known and novel susceptibility genes from the GENESIS study, and implications for multigene panel testing von Girard, Elodie, Eon‐marchais, Séverine, Olaso, Robert E, Renault, Anne‐laure, Damiola, Francesca, Dondon, Marie‐gabrielle, Barjhoux, Laure, Goidin, Didier, Meyer, Vincent, Le Gal, Dorothée, Beauvallet, Juana, Mebirouk, Noura, Lonjou, Christine, Coignard, Juliette, Marcou, Morgane, Cavaciuti, Eve, Baulard, Céline, Bihoreau, Marie‐thérèse, Cohen‐haguenauer, Odile, Leroux, Dominique, Penet, Clotilde, Fert‐ferrer, Sandra, Colas, Chrystelle, Frébourg, Thierry, Eisinger, Francois, Adenis, Claude, Fajac, Anne, Gladieff, Laurence, Tinat, Julie, Floquet, Anne, Chiesa, Jean, Giraud, Sophie, Mortemousque, Isabelle, Soubrier, Florent, Audebert‐bellanger, Séverine, Limacher, Jean‐marc, Lasset, Christine C., Lejeune‐dumoulin, Sophie, Dreyfus, Hélène, Bignon, Yves‐jean, Longy, Michel, Pujol, Pascal, Venat‐bouvet, Laurence, Bonadona, Valerie V., Berthet, Pascaline, Luporsi, Elisabeth, Maugard, Christine, Noguès, Catherine, Delnatte, Capucine, Fricker, Jean‐pierre, Gesta, Paul, Faivre, Laurence, Lortholary, Alain, Buecher, Bruno, Caron, Olivier, Gauthier‐villars, Marion, Coupier, Isabelle, Servant, Nicolas, Boland, Anne, Mazoyer, Sylvie, Deleuze, Jean‐françois, Stoppa‐lyonnet, Dominique, Andrieu, Nadine N., Lesueur, Fabienne

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A new titinopathy von de Cid, Rafael, Ben Yaou, Rabah, Roudaut, Carinne, Charton, Karine, Baulande, Sylvain, Leturcq, France, Romero, Norma Beatriz, Malfatti, Edoardo, Beuvin, Maud, Vihola, Anna, Criqui, Audrey, Nelson, Isabelle, Nectoux, Juliette, Ben Aim, Laurène, Caloustian, Christophe, Olaso, Robert E, Udd, Bjarne, Bonne, Gisèle, Eymard, Bruno, Richard, Isabelle

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Histone variant H2A.J accumulates in senescent cells and promotes inflammatory gene expression von Contrepois, Kévin, Coudereau, Clément, Benayoun, Bérénice A., Schuler, Nadine, Roux, Pierre-François, Bischof, Oliver, Courbeyrette, Régis, Carvalho, Cyril, Thuret, Jean-Yves, Ma, Zhihai, Derbois, Céline, Nevers, Marie-Claire, Volland, Hervé, Redon, Christophe E., Bonner, William M., Deleuze, Jean-François, Wiel, Clotilde, Bernard, David, Snyder, Michael P., Rübe, Claudia E., Olaso, Robert, Fenaille, François, Mann, Carl

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An artificial neural network approach integrating plasma proteomics and genetic data identifies PLXNA4 as a new susceptibility locus for pulmonary embolism von Razzaq, Misbah, Iglesias, Maria Jesus, Ibrahim-Kosta, Manal, Goumidi, Louisa, Soukarieh, Omar, Proust, Carole, Roux, Maguelonne, Suchon, Pierre, Boland, Anne, Daiain, Delphine, Olaso, Robert, Havervall, Sebastian, Thalin, Charlotte, Butler, Lynn, Deleuze, Jean-François, Odeberg, Jacob, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre

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Human genetic structure in Northwest France provides new insights into West European historical demography von Alves, Isabel, Giemza, Joanna, Blum, Michael G. B., Bernhardsson, Carolina, Chatel, Stéphanie, Karakachoff, Matilde, Saint Pierre, Aude, Herzig, Anthony F., Olaso, Robert, Monteil, Martial, Gallien, Véronique, Cabot, Elodie, Svensson, Emma, Bacq, Delphine, Baron, Estelle, Berthelier, Charlotte, Besse, Céline, Blanché, Hélène, Bocher, Ozvan, Boland, Anne, Bonnaud, Stéphanie, Charpentier, Eric, Dandine-Roulland, Claire, Férec, Claude, Fruchet, Christine, Lecointe, Simon, Le Floch, Edith, Ludwig, Thomas E., Marenne, Gaëlle, Meyer, Vincent, Quellery, Elisabeth, Racimo, Fernando, Rouault, Karen, Sandron, Florian, Schott, Jean-Jacques, Velo-Suarez, Lourdes, Violleau, Jade, Willerslev, Eske, Coativy, Yves, Jézéquel, Mael, Le Bris, Daniel, Nicolas, Clément, Pailler, Yvan, Goldberg, Marcel, Zins, Marie, Le Marec, Hervé, Jakobsson, Mattias, Darlu, Pierre, Génin, Emmanuelle, Deleuze, Jean-François, Redon, Richard, Dina, Christian

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Minor allele of the factor V K858R variant protects from venous thrombosis only in non-carriers of factor V Leiden mutation von Ibrahim-Kosta, M., Suchon, P., Couturaud, F., Smadja, D., Olaso, R., Germain, M., Saut, N., Goumidi, L., Derbois, C., Thibord, F., Debette, S., Amouyel, P., Deleuze, J. F., van Doorn, P., Castoldi, E., Patin, E., Alessi, M. C., Trégouët, D. A., Morange, P. E.

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Investigation of candidate gene copy number identifies FCGR3B as a potential biomarker for rheumatoid arthritis von Ben Kilani, Mohamed Sahbi, Cornélis, François, Olaso, Robert, Chaudru, Valerie, Petit-Teixeira, Elisabeth

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Deep intronic NIPBL de novo mutations and differential diagnoses revealed by whole genome and RNA sequencing in Cornelia de Lange syndrome patients von Coursimault, Juliette, Cassinari, Kévin, Lecoquierre, François, Quenez, Olivier, Coutant, Sophie, Derambure, Céline, Vezain, Myriam, Drouot, Nathalie, Vera, Gabriella, Schaefer, Elise, Philippe, Anaïs, Doray, Bérénice, Lambert, Laëtitia, Ghoumid, Jamal, Smol, Thomas, Rama, Mélanie, Legendre, Marine, Lacombe, Didier, Fergelot, Patricia, Olaso, Robert, Boland, Anne, Deleuze, Jean‐François, Goldenberg, Alice, Saugier‐Veber, Pascale, Nicolas, Gaël

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Wnt4 Overexpression Disrupts Normal Testicular Vasculature and Inhibits Testosterone Synthesis by Repressing Steroidogenic Factor 1/β-Catenin Synergy von Jordan, Brian K., Jennifer H. -C. Shen, Olaso, Robert, Ingraham, Holly A., Vilain, Eric

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Genome-Wide Search for Nonadditive Allele Effects Identifies PSKH2 as Involved in the Variability of Factor V Activity von Gendre, Blandine, Martinez-Perez, Angel, Kleber, Marcus E, van Hylckama Vlieg, Astrid, Boland, Anne, Olaso, Robert, Germain, Marine, Munsch, Gaëlle, Moissl, Angela Patricia, Suchon, Pierre, Souto, Juan Carlos, Soria, José Manuel, Deleuze, Jean-François, März, Winfried, Rosendaal, Frits R, Sabater-Lleal, Maria, Morange, Pierre-Emmanuel, Trégouët, David-Alexandre

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Is there still room for additional common susceptibility alleles for venous thromboembolism? von Trégouët, D. A., Delluc, A., Roche, A., Derbois, C., Olaso, R., Germain, M., Andrade, M., Tang, W., Chasman, D. I., Hylckama Vlieg, A., Reitsma, P. H., Kabrhel, C., Smith, N., Morange, P. E.

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