Loss-of-function variants in ATM confer risk of gastric cancer von Helgason, Hannes, Rafnar, Thorunn, Olafsdottir, Halla S, Jonasson, Jon G, Sigurdsson, Asgeir, Stacey, Simon N, Jonasdottir, Adalbjorg, Tryggvadottir, Laufey, Alexiusdottir, Kristin, Haraldsson, Asgeir, le Roux, Louise, Gudmundsson, Julius, Johannsdottir, Hrefna, Oddsson, Asmundur, Gylfason, Arnaldur, Magnusson, Olafur T, Masson, Gisli, Jonsson, Thorvaldur, Skuladottir, Halla, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Sulem, Patrick, Stefansson, Kari

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Effect of booster vaccination against Delta and Omicron SARS-CoV-2 variants in Iceland von Norddahl, Gudmundur L., Melsted, Pall, Gunnarsdottir, Kristbjorg, Halldorsson, Gisli H., Olafsdottir, Thorunn A., Gylfason, Arnaldur, Kristjansson, Mar, Magnusson, Olafur T., Sulem, Patrick, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Stefansson, Kari

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Sequence variant at 8q24.21 associates with sciatica caused by lumbar disc herniation von Bjornsdottir, Gyda, Benonisdottir, Stefania, Sveinbjornsson, Gardar, Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Walters, G. Bragi, Bjornsson, Aron, Olafsson, Ingvar H., Ulfarsson, Elfar, Vikingsson, Arnor, Hansdottir, Ragnheidur, Karlsson, Karl O., Rafnar, Thorunn, Jonsdottir, Ingileif, Frigge, Michael L., Kong, Augustine, Oddsson, Asmundur, Masson, Gisli, Magnusson, Olafur T., Gudbjartsson, Tomas, Stefansson, Hreinn, Sulem, Patrick, Gudbjartsson, Daniel, Thorsteinsdottir, Unnur, Thorgeirsson, Thorgeir E., Stefansson, Kari

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Peripheral blood transcriptome profiling enables monitoring disease progression in dystrophic mice and patients von Signorelli, Mirko, Ebrahimpoor, Mitra, Veth, Olga, Hettne, Kristina, Verwey, Nisha, García‐Rodríguez, Raquel, Tanganyika‐deWinter, Christa L, Lopez Hernandez, Luz B, Escobar Cedillo, Rosa, Gómez Díaz, Benjamín, Magnusson, Olafur T, Mei, Hailiang, Tsonaka, Roula, Aartsma‐Rus, Annemieke, Spitali, Pietro

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COPA syndrome in an Icelandic family caused by a recurrent missense mutation in COPA von Jensson, Brynjar O, Hansdottir, Sif, Arnadottir, Gudny A, Sulem, Gerald, Kristjansson, Ragnar P, Oddsson, Asmundur, Benonisdottir, Stefania, Jonsson, Hakon, Helgason, Agnar, Saemundsdottir, Jona, Magnusson, Olafur T, Masson, Gisli, Thorisson, Gudmundur A, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Jonsdottir, Ingileif, Petursdottir, Vigdis, Kristinsson, Jon R, Gudbjartsson, Daniel F, Thorsteinsdottir, Unnur, Arngrimsson, Reynir, Sulem, Patrick, Gudmundsson, Gunnar, Stefansson, Kari

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Clonal hematopoiesis, with and without candidate driver mutations, is common in the elderly von Zink, Florian, Stacey, Simon N., Norddahl, Gudmundur L., Frigge, Michael L., Magnusson, Olafur T., Jonsdottir, Ingileif, Thorgeirsson, Thorgeir E., Sigurdsson, Asgeir, Gudjonsson, Sigurjon A., Gudmundsson, Julius, Jonasson, Jon G., Tryggvadottir, Laufey, Jonsson, Thorvaldur, Helgason, Agnar, Gylfason, Arnaldur, Sulem, Patrick, Rafnar, Thorunn, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F., Masson, Gisli, Kong, Augustine, Stefansson, Kari

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Long-read sequencing of 3,622 Icelanders provides insight into the role of structural variants in human diseases and other traits von Beyter, Doruk, Ingimundardottir, Helga, Oddsson, Asmundur, Eggertsson, Hannes P., Bjornsson, Eythor, Jonsson, Hakon, Atlason, Bjarni A., Kristmundsdottir, Snaedis, Mehringer, Svenja, Hardarson, Marteinn T., Gudjonsson, Sigurjon A., Magnusdottir, Droplaug N., Jonasdottir, Aslaug, Jonasdottir, Adalbjorg, Kristjansson, Ragnar P., Sverrisson, Sverrir T., Holley, Guillaume, Palsson, Gunnar, Stefansson, Olafur A., Eyjolfsson, Gudmundur, Olafsson, Isleifur, Sigurdardottir, Olof, Torfason, Bjarni, Masson, Gisli, Helgason, Agnar, Thorsteinsdottir, Unnur, Holm, Hilma, Gudbjartsson, Daniel F., Sulem, Patrick, Magnusson, Olafur T., Halldorsson, Bjarni V., Stefansson, Kari

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A mutation in APP protects against Alzheimer’s disease and age-related cognitive decline von Jonsson, Thorlakur, Atwal, Jasvinder K., Steinberg, Stacy, Snaedal, Jon, Jonsson, Palmi V., Bjornsson, Sigurbjorn, Stefansson, Hreinn, Sulem, Patrick, Gudbjartsson, Daniel, Maloney, Janice, Hoyte, Kwame, Gustafson, Amy, Liu, Yichin, Lu, Yanmei, Bhangale, Tushar, Graham, Robert R., Huttenlocher, Johanna, Bjornsdottir, Gyda, Andreassen, Ole A., Jönsson, Erik G., Palotie, Aarno, Behrens, Timothy W., Magnusson, Olafur T., Kong, Augustine, Thorsteinsdottir, Unnur, Watts, Ryan J., Stefansson, Kari

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Insights into imprinting from parent-of-origin phased methylomes and transcriptomes von Zink, Florian, Magnusdottir, Droplaug N., Magnusson, Olafur T., Walker, Nicolas J., Morris, Tiffany J., Sigurdsson, Asgeir, Halldorsson, Gisli H., Gudjonsson, Sigurjon A., Melsted, Pall, Ingimundardottir, Helga, Kristmundsdottir, Snædis, Alexandersson, Kristjan F., Helgadottir, Anna, Gudmundsson, Julius, Rafnar, Thorunn, Jonsdottir, Ingileif, Holm, Hilma, Eyjolfsson, Gudmundur Ingi, Sigurdardottir, Olof, Olafsson, Isleifur, Masson, Gisli, Gudbjartsson, Daniel F., Thorsteinsdottir, Unnur, Halldorsson, Bjarni V., Stacey, Simon N., Stefansson, Kari

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Design of phosphodiesterase 4D (PDE4D) allosteric modulators for enhancing cognition with improved safety von Burgin, Alex B, Gurney, Mark E, Magnusson, Olafur T, Singh, Jasbir, Witte, Pam, Staker, Bart L, Bjornsson, Jon M, Thorsteinsdottir, Margret, Hrafnsdottir, Sigrun, Hagen, Timothy, Kiselyov, Alex S, Stewart, Lance J

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Identification of low-frequency and rare sequence variants associated with elevated or reduced risk of type 2 diabetes von Steinthorsdottir, Valgerdur, Thorleifsson, Gudmar, Sulem, Patrick, Helgason, Hannes, Grarup, Niels, Sigurdsson, Asgeir, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Magnusson, Olafur T, Gudjonsson, Sigurjon A, Justesen, Johanne M, Harder, Marie N, Jørgensen, Marit E, Christensen, Cramer, Brandslund, Ivan, Sandbæk, Annelli, Lauritzen, Torsten, Vestergaard, Henrik, Linneberg, Allan, Jørgensen, Torben, Hansen, Torben, Daneshpour, Maryam S, Fallah, Mohammad-Sadegh, Hreidarsson, Astradur B, Sigurdsson, Gunnar, Azizi, Fereidoun, Benediktsson, Rafn, Masson, Gisli, Helgason, Agnar, Kong, Augustine, Gudbjartsson, Daniel F, Pedersen, Oluf, Thorsteinsdottir, Unnur, Stefansson, Kari

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HLA class II sequence variants influence tuberculosis risk in populations of European ancestry von Sveinbjornsson, Gardar, Gudbjartsson, Daniel F, Halldorsson, Bjarni V, Kristinsson, Karl G, Gottfredsson, Magnus, Barrett, Jeffrey C, Gudmundsson, Larus J, Blondal, Kai, Gylfason, Arnaldur, Gudjonsson, Sigurjon Axel, Helgadottir, Hafdis T, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Karason, Ari, Kardum, Ljiljana Bulat, Knežević, Jelena, Kristjansson, Helgi, Kristjansson, Mar, Love, Arthur, Luo, Yang, Magnusson, Olafur T, Sulem, Patrick, Kong, Augustine, Masson, Gisli, Thorsteinsdottir, Unnur, Dembic, Zlatko, Nejentsev, Sergey, Blondal, Thorsteinn, Jonsdottir, Ingileif, Stefansson, Kari

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A rare IL33 loss-of-function mutation reduces blood eosinophil counts and protects from asthma von Smith, Dirk, Helgason, Hannes, Sulem, Patrick, Bjornsdottir, Unnur Steina, Lim, Ai Ching, Sveinbjornsson, Gardar, Hasegawa, Haruki, Brown, Michael, Ketchem, Randal R, Gavala, Monica, Garrett, Logan, Jonasdottir, Adalbjorg, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Magnusson, Olafur T, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Onundarson, Pall Torfi, Sigurdardottir, Olof, Gislason, David, Gislason, Thorarinn, Ludviksson, Bjorn Runar, Ludviksdottir, Dora, Boezen, H Marike, Heinzmann, Andrea, Krueger, Marcus, Porsbjerg, Celeste, Ahluwalia, Tarunveer S, Waage, Johannes, Backer, Vibeke, Deichmann, Klaus A, Koppelman, Gerard H, Bønnelykke, Klaus, Bisgaard, Hans, Masson, Gisli, Thorsteinsdottir, Unnur, Gudbjartsson, Daniel F, Johnston, James A, Jonsdottir, Ingileif, Stefansson, Kari

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Mutations in BRIP1 confer high risk of ovarian cancer von Rafnar, Thorunn, Stefansson, Kari, Gudbjartsson, Daniel F, Sulem, Patrick, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Jonasdottir, Adalbjorg, Besenbacher, Soren, Lundin, Pär, Stacey, Simon N, Gudmundsson, Julius, Magnusson, Olafur T, le Roux, Louise, Orlygsdottir, Gudbjorg, Helgadottir, Hafdis T, Johannsdottir, Hrefna, Gylfason, Arnaldur, Tryggvadottir, Laufey, Jonasson, Jon G, de Juan, Ana, Ortega, Eugenia, Ramon-Cajal, Jose M, García-Prats, Maria D, Mayordomo, Carlos, Panadero, Angeles, Rivera, Fernando, Aben, Katja K H, van Altena, Anne M, Massuger, Leon F A G, Aavikko, Mervi, Kujala, Paula M, Staff, Synnöve, Aaltonen, Lauri A, Olafsdottir, Kristrun, Bjornsson, Johannes, Kong, Augustine, Salvarsdottir, Anna, Saemundsson, Hafsteinn, Olafsson, Karl, Benediktsdottir, Kristrun R, Gulcher, Jeffrey, Masson, Gisli, Kiemeney, Lambertus A, Mayordomo, Jose I, Thorsteinsdottir, Unnur

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Histopathology and levels of proteins in plasma associate with survival after colorectal cancer diagnosis von Magnusson, Magnus I., Agnarsson, Bjarni A., Jonasson, Jon G., Tryggvason, Thordur, Aeffner, Famke, le Roux, Louise, Magnusdottir, Droplaug N., Gunnarsdottir, Helga S., Alexíusdóttir, Kristín K., Gunnarsdottir, Kristbjorg, Söebech, Emilia, Runarsdottir, Hjaltey, Jonsdottir, Erna M., Kristinsdottir, Bjarney S., Olafsson, Sigurgeir, Knutsdottir, Hildur, Thorsteinsdottir, Unnur, Ulfarsson, Magnus O., Gudbjartsson, Daniel F., Saemundsdottir, Jona, Magnusson, Olafur T., Norddahl, Gudmundur L., Watson, J. E. Vivienne, Rafnar, Thorunn, Lund, Sigrun H., Stefansson, Kari

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Discovery of common variants associated with low TSH levels and thyroid cancer risk von Gudmundsson, Julius, Sulem, Patrick, Gudbjartsson, Daniel F, Jonasson, Jon G, Masson, Gisli, He, Huiling, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Stacey, Simon N, Johannsdottir, Hrefna, Th Helgadottir, Hafdis, Li, Wei, Nagy, Rebecca, Ringel, Matthew D, Kloos, Richard T, de Visser, Marieke C H, Plantinga, Theo S, den Heijer, Martin, Aguillo, Esperanza, Panadero, Angeles, Prats, Enrique, Garcia-Castaño, Almudena, De Juan, Ana, Rivera, Fernando, Walters, G Bragi, Bjarnason, Hjordis, Tryggvadottir, Laufey, Eyjolfsson, Gudmundur I, Bjornsdottir, Unnur S, Holm, Hilma, Olafsson, Isleifur, Kristjansson, Kristleifur, Kristvinsson, Hoskuldur, T Magnusson, Olafur, Thorleifsson, Gudmar, Gulcher, Jeffrey R, Kong, Augustine, Kiemeney, Lambertus ALM, Jonsson, Thorvaldur, Hjartarson, Hannes, Mayordomo, Jose I, Netea-Maier, Romana T, de la Chapelle, Albert, Hrafnkelsson, Jon, Thorsteinsdottir, Unnur, Rafnar, Thorunn, Stefansson, Kari

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Severe osteoarthritis of the hand associates with common variants within the ALDH1A2 gene and with rare variants at 1p31 von Styrkarsdottir, Unnur, Thorleifsson, Gudmar, Helgadottir, Hafdis T, Bomer, Nils, Metrustry, Sarah, Bierma-Zeinstra, S, Strijbosch, Annelieke M, Evangelou, Evangelos, Hart, Deborah, Beekman, Marian, Jonasdottir, Aslaug, Sigurdsson, Asgeir, Eiriksson, Finnur F, Thorsteinsdottir, Margret, Frigge, Michael L, Kong, Augustine, Gudjonsson, Sigurjon A, Magnusson, Olafur T, Masson, Gisli, Hofman, Albert, Arden, Nigel K, Ingvarsson, Thorvaldur, Lohmander, Stefan, Kloppenburg, Margreet, Rivadeneira, Fernando, Nelissen, Rob G H H, Spector, Tim, Uitterlinden, Andre, Slagboom, P Eline, Thorsteinsdottir, Unnur, Jonsdottir, Ingileif, Valdes, Ana M, Meulenbelt, Ingrid, van Meurs, Joyce, Jonsson, Helgi, Stefansson, Kari

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Genetic architecture of vitamin B12 and folate levels uncovered applying deeply sequenced large datasets von Grarup, Niels, Sulem, Patrick, Sandholt, Camilla H, Thorleifsson, Gudmar, Ahluwalia, Tarunveer S, Steinthorsdottir, Valgerdur, Bjarnason, Helgi, Gudbjartsson, Daniel F, Magnusson, Olafur T, Sparsø, Thomas, Albrechtsen, Anders, Kong, Augustine, Masson, Gisli, Tian, Geng, Cao, Hongzhi, Nie, Chao, Kristiansen, Karsten, Husemoen, Lise Lotte, Thuesen, Betina, Li, Yingrui, Nielsen, Rasmus, Linneberg, Allan, Olafsson, Isleifur, Eyjolfsson, Gudmundur I, Jørgensen, Torben, Wang, Jun, Hansen, Torben, Thorsteinsdottir, Unnur, Stefánsson, Kari, Pedersen, Oluf

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The Structure of a Biosynthetic Intermediate of Pyrroloquinoline Quinone (PQQ) and Elucidation of the Final Step of PQQ Biosynthesis von Magnusson, Olafur T, Toyama, Hirohide, Saeki, Megumi, Schwarzenbacher, Robert, Klinman, Judith P

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Identification of low-frequency variants associated with gout and serum uric acid levels von Sulem, Patrick, Stefansson, Kari, Gudbjartsson, Daniel F, Walters, G Bragi, Helgadottir, Hafdis T, Helgason, Agnar, Gudjonsson, Sigurjon A, Zanon, Carlo, Besenbacher, Soren, Bjornsdottir, Gyda, Magnusson, Olafur T, Magnusson, Gisli, Hjartarson, Eirikur, Saemundsdottir, Jona, Gylfason, Arnaldur, Jonasdottir, Adalbjorg, Holm, Hilma, Karason, Ari, Rafnar, Thorunn, Stefansson, Hreinn, Andreassen, Ole A, Pedersen, Jesper H, Pack, Allan I, de Visser, Marieke C H, Kiemeney, Lambertus A, Geirsson, Arni J, Eyjolfsson, Gudmundur I, Olafsson, Isleifur, Kong, Augustine, Masson, Gisli, Jonsson, Helgi, Thorsteinsdottir, Unnur, Jonsdottir, Ingileif

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