Pembrolizumab in advanced soft-tissue sarcoma and bone sarcoma (SARC028): a multicentre, two-cohort, single-arm, open-label, phase 2 trial von Tawbi, Hussein A, Burgess, Melissa, Bolejack, Vanessa, Van Tine, Brian A, Schuetze, Scott M, Hu, James, D'Angelo, Sandra, Attia, Steven, Riedel, Richard F, Priebat, Dennis A, Movva, Sujana, Davis, Lara E, Okuno, Scott H, Reed, Damon R, Crowley, John, Butterfield, Lisa H, Salazar, Ruth, Rodriguez-Canales, Jaime, Lazar, Alexander J, Wistuba, Ignacio I, Baker, Laurence H, Maki, Robert G, Reinke, Denise, Patel, Shreyaskumar

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Correlative Analyses of the SARC028 Trial Reveal an Association Between Sarcoma-Associated Immune Infiltrate and Response to Pembrolizumab von Keung, Emily Z., Burgess, Melissa, Salazar, Ruth, Parra, Edwin R., Rodrigues-Canales, Jaime, Bolejack, Vanessa, Van Tine, Brian A., Schuetze, Scott M., Attia, Steven, Riedel, Richard F., Hu, James, Okuno, Scott H., Priebat, Dennis A., Movva, Sujana, Davis, Lara E., Reed, Damon R., Reuben, Alexandre, Roland, Christina L., Reinke, Denise, Lazar, Alexander J., Wang, Wei-Lien, Wargo, Jennifer A., Tawbi, Hussein A.

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Safety, pharmacokinetics, and preliminary activity of the anti-IGF-1R antibody figitumumab (CP-751,871) in patients with sarcoma and Ewing's sarcoma: a phase 1 expansion cohort stu... von Olmos, David, MD, Postel-Vinay, Sophie, MD, Molife, L Rhoda, MD, Okuno, Scott H, MD, Schuetze, Scott M, MD, Paccagnella, M Luisa, PhD, Batzel, Gretchen N, MD, Yin, Donghua, PhD, Pritchard-Jones, Kathryn, Prof, Judson, Ian, Prof, Worden, Francis P, MD, Gualberto, Antonio, MD, Scurr, Michelle, MD, de Bono, Johann S, Dr, Haluska, Paul, MD

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Cixutumumab and temsirolimus for patients with bone and soft-tissue sarcoma: a multicentre, open-label, phase 2 trial von Schwartz, Gary K, Prof, Tap, William D, MD, Qin, Li-Xuan, PhD, Livingston, Michael B, Prof, Undevia, Samir D, MD, Chmielowski, Bartosz, MD, Agulnik, Mark, MD, Schuetze, Scott M, MD, Reed, Damon R, MD, Okuno, Scott H, Prof, Ludwig, Joseph A, MD, Keedy, Vicki, MD, Rietschel, Petra, MD, Kraft, Andrew S, Prof, Adkins, Douglas, Prof, Van Tine, Brian A, MD, Brockstein, Bruce, MD, Yim, Vincent, BA, Bitas, Christiana, BA, Abdullah, Abdul, BA, Antonescu, Cristina R, Prof, Condy, Mercedes, RN, Dickson, Mark A, MD, Vasudeva, Shyamprasad Deraje, MA, Ho, Alan L, MD, Doyle, L Austin, Prof, Chen, Helen X, Prof, Maki, Robert G, Prof

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Phase II study of the safety and antitumor activity of the hypoxia-activated prodrug TH-302 in combination with doxorubicin in patients with advanced soft tissue sarcoma von Chawla, Sant P, Cranmer, Lee D, Van Tine, Brian A, Reed, Damon R, Okuno, Scott H, Butrynski, James E, Adkins, Douglas R, Hendifar, Andrew E, Kroll, Stew, Ganjoo, Kristen N

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Pathological response in children and adults with large unresected intermediate-grade or high-grade soft tissue sarcoma receiving preoperative chemoradiotherapy with or without paz... von Weiss, Aaron R, Chen, Yen-Lin, Scharschmidt, Thomas J, Chi, Yueh-Yun, Tian, Jing, Black, Jennifer O, Davis, Jessica L, Fanburg-Smith, Julie C, Zambrano, Eduardo, Anderson, James, Arens, Robin, Binitie, Odion, Choy, Edwin, Davis, Justin W, Hayes-Jordan, Andrea, Kao, Simon C, Kayton, Mark L, Kessel, Sandy, Lim, Ruth, Meyer, William H, Million, Lynn, Okuno, Scott H, Ostrenga, Andrew, Parisi, Marguerite T, Pryma, Daniel A, Randall, R Lor, Rosen, Mark A, Schlapkohl, Mary, Shulkin, Barry L, Smith, Ethan A, Sorger, Joel I, Terezakis, Stephanie, Hawkins, Douglas S, Spunt, Sheri L, Wang, Dian

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A novel classification system for spinal instability in neoplastic disease: an evidence-based approach and expert consensus from the Spine Oncology Study Group von Fisher, Charles G, DiPaola, Christian P, Ryken, Timothy C, Bilsky, Mark H, Shaffrey, Christopher I, Berven, Sigurd H, Harrop, James S, Fehlings, Michael G, Boriani, Stefano, Chou, Dean, Schmidt, Meic H, Polly, David W, Biagini, Roberto, Burch, Shane, Dekutoski, Mark B, Ganju, Aruna, Gerszten, Peter C, Gokaslan, Ziya L, Groff, Michael W, Liebsch, Norbert J, Mendel, Ehud, Okuno, Scott H, Patel, Shreyaskumar, Rhines, Laurence D, Rose, Peter S, Sciubba, Daniel M, Sundaresan, Narayan, Tomita, Katsuro, Varga, Peter P, Vialle, Luiz R, Vrionis, Frank D, Yamada, Yoshiya, Fourney, Daryl R

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Inhibition of STAT3 blocks protein synthesis and tumor metastasis in osteosarcoma cells von Zuo, Dongqing, Shogren, Kristen L, Zang, Jie, Jewison, Donna E, Waletzki, Brian E, Miller, 2nd, Alan L, Okuno, Scott H, Cai, Zhengdong, Yaszemski, Michael J, Maran, Avudaiappan

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RNA-dependent protein kinase is required for interferon-γ-induced autophagy in MG63 osteosarcoma cells von Xu, Jie, Ji, Yuqing, Shogren, Kristen L., Okuno, Scott H., Yaszemski, Michael J., Maran, Avudaiappan

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Phase II Randomized Study of CMB305 and Atezolizumab Compared With Atezolizumab Alone in Soft-Tissue Sarcomas Expressing NY-ESO-1 von Chawla, Sant P, Van Tine, Brian A, Pollack, Seth M, Ganjoo, Kristen N, Elias, Anthony D, Riedel, Richard F, Attia, Steven, Choy, Edwin, Okuno, Scott H, Agulnik, Mark, von Mehren, Margaret, Livingston, Michael B, Keedy, Vicki L, Verschraegen, Claire F, Philip, Tony, Bohac, G Chet, Yurasov, Sergey, Yakovich, Adam, Lu, Hailing, Chen, Michael, Maki, Robert G

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Randomized phase II study of gemcitabine and docetaxel compared with gemcitabine alone in patients with metastatic soft tissue sarcomas von MAKI, Robert G, WATHEN, J. Kyle, THALL, Peter F, BENJAMIN, Robert S, BAKER, Laurence H, HENSLEY, Martee L, PATEL, Shreyaskumar R, PRIEBAT, Dennis A, OKUNO, Scott H, SAMUELS, Brian, FANUCCHI, Michael, HARMON, David C, SCHUETZE, Scott M, REINKE, Denise

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Atezolizumab for Advanced Alveolar Soft Part Sarcoma von Chen, Alice P., Sharon, Elad, O’Sullivan-Coyne, Geraldine, Moore, Nancy, Foster, Jared C., Hu, James S., Van Tine, Brian A., Conley, Anthony P., Read, William L., Riedel, Richard F., Burgess, Melissa A., Glod, John, Davis, Elizabeth J., Merriam, Priscilla, Naqash, Abdul R., Fino, Kristin K., Miller, Brandon L., Wilsker, Deborah F., Begum, Asma, Ferry-Galow, Katherine V., Deshpande, Hari A., Schwartz, Gary K., Ladle, Brian H., Okuno, Scott H., Beck, Jill C., Chen, James L., Takebe, Naoko, Fogli, Laura K., Rosenberger, Christina L., Parchment, Ralph E., Doroshow, James H.

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Cardiac Metastasis from Myxoid Liposarcoma Managed Successfully with Chemotherapy and Radiotherapy: Case Report and Review of the Literature von Stergiopoulos, Georgios M, Siontis, Brittany L, Petersen, Ivy A, Houdek, Matthew T, Ho, Thanh P, Okuno, Scott H, Robinson, Steven I

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Malignant Primary Cardiac Tumors : Review of a Single Institution Experience von SIMPSON, Lijo, KUMAR, Shaji K, OKUNO, Scott H, SCHAFF, Hartzell V, PORRATA, Luis F, BUCKNER, Jan C, MOYNIHAN, Timothy J

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Targeting Refractory Sarcomas and Malignant Peripheral Nerve Sheath Tumors in a Phase I/II Study of Sirolimus in Combination with Ganetespib (SARC023) von De Raedt, Thomas, Chawla, Sant, Van Tine, Brian A., O’Sullivan, Geraldine, Chen, Alice, Cichowski, Karen, Widemann, Brigitte C., Wolters, Pamela L., Basu, Mitali, Perentesis, John, Maertens, Ophélia, Reinke, Denise, Okuno, Scott H., Lu, Yao, Kim, AeRang, Chugh, Rashmi

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Phase II Trial of Neoadjuvant/adjuvant Imatinib Mesylate for Advanced Primary and Metastatic/recurrent Operable Gastrointestinal Stromal Tumors: Long-term Follow-up Results of Radi... von Wang, Dian, Zhang, Qiang, Blanke, Charles D., Demetri, George D., Heinrich, Michael C., Watson, James C., Hoffman, John P., Okuno, Scott, Kane, John M., von Mehren, Margaret, Eisenberg, Burton L.

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Mammalian target of rapamycin inhibitors in sarcomas von Okuno, Scott

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Decreased local and systemic levels of sFRP3 protein in osteosarcoma patients von Bravo, Dalibel, Salduz, Ahmet, Shogren, Kristen L., Okuno, Madison N., Herrick, James L., Okuno, Scott H., Galindo, Mario, van Wijnen, Andre J., Yaszemski, Michael J., Maran, Avudaiappan

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Outcomes of non‐angiosarcoma radiation‐associated soft tissue sarcomas of the chest von Garayua‐Cruz, Leilani, Broida, Samuel E., Okuno, Scott H., Robinson, Steven I., Siontis, Brittany L., Welliver, Meng Xu, Wilke, Benjamin K., Goulding, Krista A., Rose, Peter S., Houdek, Matthew T.

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Evaluating the Role of Adjuvant Radiotherapy in the Management of Sacral and Vertebral Chordoma: Results from a National Database von Yolcu, Yagiz, Wahood, Waseem, Alvi, Mohammed Ali, Kerezoudis, Panagiotis, Okuno, Scott H., Foote, Robert L., Bydon, Mohamad

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