Microarray-based genomic selection for high-throughput resequencing von Zwick, Michael E, Okou, David T, Steinberg, Karyn Meltz, Middle, Christina, Cutler, David J, Albert, Thomas J

Volltext

Structure and Complexity of a Bacterial Transcriptome von PASSALACQUA, Karla D, VARADARAJAN, Anjana, ONDOV, Brian D, OKOU, David T, ZWICK, Michael E, BERGMAN, Nicholas H

Volltext

Whole-genome sequencing of African Americans implicates differential genetic architecture in inflammatory bowel disease von Somineni, Hari K., Nagpal, Sini, Venkateswaran, Suresh, Cutler, David J., Okou, David T., Haritunians, Talin, Simpson, Claire L., Begum, Ferdouse, Datta, Lisa W., Quiros, Antonio J., Seminerio, Jenifer, Mengesha, Emebet, Alexander, Jonathan S., Baldassano, Robert N., Dudley-Brown, Sharon, Cross, Raymond K., Dassopoulos, Themistocles, Denson, Lee A., Dhere, Tanvi A., Iskandar, Heba, Dryden, Gerald W., Hou, Jason K., Hussain, Sunny Z., Hyams, Jeffrey S., Isaacs, Kim L., Kader, Howard, Kappelman, Michael D., Katz, Jeffry, Kellermayer, Richard, Kuemmerle, John F., Lazarev, Mark, Li, Ellen, Mannon, Peter, Moulton, Dedrick E., Newberry, Rodney D., Patel, Ashish S., Pekow, Joel, Saeed, Shehzad A., Valentine, John F., Wang, Ming-Hsi, McCauley, Jacob L., Abreu, Maria T., Jester, Traci, Molle-Rios, Zarela, Palle, Sirish, Scherl, Ellen J., Kwon, John, Rioux, John D., Duerr, Richard H., Silverberg, Mark S., Zwick, Michael E., Stevens, Christine, Daly, Mark J., Cho, Judy H., Gibson, Greg, McGovern, Dermot P.B., Brant, Steven R., Kugathasan, Subra

Volltext

Methylation quantitative trait loci are largely consistent across disease states in Crohn's disease von Venkateswaran, Suresh, Somineni, Hari K, Kilaru, Varun, Katrinli, Seyma, Prince, Jarod, Okou, David T, Hyams, Jeffrey S, Denson, Lee A, Kellermayer, Richard, Gibson, Greg, Cutler, David J, Smith, Alicia K, Kugathasan, Subra, Conneely, Karen N

Volltext

Large-scale sequencing identifies multiple genes and rare variants associated with Crohn’s disease susceptibility von Stevens, Christine R., Venkataraman, Guhan R., Avila, Brandon, Abreu, Maria T., Ahmad, Tariq, Allez, Matthieu, Ananthakrishnan, Ashwin N., Barrett, Jeffrey C., Barzilai, Nir, Beaugerie, Laurent, Beecham, Ashley, Bokemeyer, Bernd, Chan, Andrew, Cleynen, Isabelle, Cosnes, Jacques, Cutler, David J., Daly, Allan, Damas, Oriana M., Datta, Lisa W., Dawany, Noor, Devoto, Marcella, Dodge, Sheila, Ellinghaus, Eva, Farkkila, Martti, Faubion, William, Ferreira, Manuel, Gabriel, Stacey B., Ge, Tian, Georges, Michel, Gettler, Kyle, Giri, Mamta, Goyette, Philippe, Graham, Daniel, Hämäläinen, Eija, Haritunians, Talin, Heap, Graham A., Hiltunen, Mikko, Hoeppner, Marc, Horowitz, Julie E., Iyer, Vivek, Kelsen, Judith, Khalili, Hamed, Kirschner, Barbara S., Koskela, Jukka T., Kugathasan, Subra, Kupcinskas, Juozas, Laudes, Matthias, Levine, Adam P., Liefferinckx, Claire, Loescher, Britt-Sabina, Louis, Edouard, Mansfield, John, May, Sandra, McCauley, Jacob L., Mengesha, Emebet, Mni, Myriam, Moayyedi, Paul, Newberry, Rodney D., Okou, David T., Ostrer, Harry, Paquette, Jean, Pekow, Joel, Pierik, Marieke J., Ponsioen, Cyriel Y., Pontikos, Nikolas, Prescott, Natalie, Pulver, Ann E., Rahmouni, Souad, Sands, Bruce, Sartor, R. Balfour, Schiff, Elena R., Schreiber, Stefan, Schumm, L. Philip, Segal, Anthony W., Seksik, Philippe, Sheikh, Shehzad Z., Silverberg, Mark S., Simmons, Alison, Skeiceviciene, Jurgita, Sokol, Harry, Solomonson, Matthew, Somineni, Hari, Sun, Dylan, Targan, Stephan, Turner, Dan, van der Meulen, Andrea E., Vermeire, Séverine, Verstockt, Sare, Voskuil, Michiel D., Duerr, Richard H., Franke, Andre, Brant, Steven R., Cho, Judy, Parkes, Miles, Xavier, Ramnik J., Rivas, Manuel A., Rioux, John D., McGovern, Dermot P. B., Huang, Hailiang, Anderson, Carl A.

Volltext

Predicting adverse drug reactions of two‐drug combinations using structural and transcriptomic drug representations to train an artificial neural network von Shankar, Susmitha, Bhandari, Ishita, Okou, David T., Srinivasa, Gowri, Athri, Prashanth

Volltext

Blood-Derived DNA Methylation Signatures of Crohn's Disease and Severity of Intestinal Inflammation von Somineni, Hari K., Venkateswaran, Suresh, Kilaru, Varun, Marigorta, Urko M., Mo, Angela, Okou, David T., Kellermayer, Richard, Mondal, Kajari, Cobb, Dawayland, Walters, Thomas D., Griffiths, Anne, Noe, Joshua D., Crandall, Wallace V., Rosh, Joel R., Mack, David R., Heyman, Melvin B., Baker, Susan S., Stephens, Michael C., Baldassano, Robert N., Markowitz, James F., Dubinsky, Marla C., Cho, Judy, Hyams, Jeffrey S., Denson, Lee A., Gibson, Greg, Cutler, David J., Conneely, Karen N., Smith, Alicia K., Kugathasan, Subra

Volltext

Clinical and Genomic Correlates of Neutrophil Reactive Oxygen Species Production in Pediatric Patients With Crohn’s Disease von Denson, Lee A., Jurickova, Ingrid, Karns, Rebekah, Shaw, Kelly A., Cutler, David J., Okou, David T., Dodd, Anne, Quinn, Kathryn, Mondal, Kajari, Aronow, Bruce J., Haberman, Yael, Linn, Aaron, Price, Adam, Bezold, Ramona, Lake, Kathleen, Jackson, Kimberly, Walters, Thomas D., Griffiths, Anne, Baldassano, Robert N., Noe, Joshua D., Hyams, Jeffrey S., Crandall, Wallace V., Kirschner, Barbara S., Heyman, Melvin B., Snapper, Scott, Guthery, Stephen L., Dubinsky, Marla C., Leleiko, Neal S., Otley, Anthony R., Xavier, Ramnik J., Stevens, Christine, Daly, Mark J., Zwick, Michael E., Kugathasan, Subra

Volltext

Genome-wide Association Study Identifies African-Specific Susceptibility Loci in African Americans with Inflammatory Bowel Disease von Brant, Steven R, Okou, David T, Simpson, Claire L, Cutler, David J, Haritunians, Talin, Bradfield, Jonathan P, Chopra, Pankaj, Prince, Jarod, Begum, Ferdouse, Kumar, Archana, Huang, Chengrui, Venkateswaran, Suresh, Datta, Lisa W, Wei, Zhi, Thomas, Kelly, Herrinton, Lisa J, Klapproth, Jan-Micheal A, Quiros, Antonio J, Seminerio, Jenifer, Liu, Zhenqiu, Alexander, Jonathan S, Baldassano, Robert N, Dudley-Brown, Sharon, Cross, Raymond K, Dassopoulos, Themistocles, Denson, Lee A, Dhere, Tanvi A, Dryden, Gerald W, Hanson, John S, Hou, Jason K, Hussain, Sunny Z, Hyams, Jeffrey S, Isaacs, Kim L, Kader, Howard, Kappelman, Michael D, Katz, Jeffry, Kellermayer, Richard, Kirschner, Barbara S, Kuemmerle, John F, Kwon, John H, Lazarev, Mark, Li, Ellen, Mack, David, Mannon, Peter, Moulton, Dedrick E, Newberry, Rodney D, Osuntokun, Bankole O, Patel, Ashish S, Saeed, Shehzad A, Targan, Stephan R, Valentine, John F, Wang, Ming-Hsi, Zonca, Martin, Rioux, John D, Duerr, Richard H, Silverberg, Mark S, Cho, Judy H, Hakonarson, Hakon, Zwick, Michael E, McGovern, Dermot P.B, Kugathasan, Subra

Volltext

Identification of Polycystic Kidney Disease 1 Like 1 Gene Variants in Children With Biliary Atresia Splenic Malformation Syndrome von Berauer, John‐Paul, Mezina, Anya I., Okou, David T., Sabo, Aniko, Muzny, Donna M., Gibbs, Richard A., Hegde, Madhuri R., Chopra, Pankaj, Cutler, David J., Perlmutter, David H., Bull, Laura N., Thompson, Richard J., Loomes, Kathleen M., Spinner, Nancy B., Rajagopalan, Ramakrishnan, Guthery, Stephen L., Moore, Barry, Yandell, Mark, Harpavat, Sanjiv, Magee, John C., Kamath, Binita M., Molleston, Jean P., Bezerra, Jorge A., Murray, Karen F., Alonso, Estella M., Rosenthal, Philip, Squires, Robert H., Wang, Kasper S., Finegold, Milton J., Russo, Pierre, Sherker, Averell H., Sokol, Ronald J., Karpen, Saul J.

Volltext

Early Onset Granulomatous Colitis Associated with a Mutation in NCF4 Resolved with Hematopoietic Stem Cell Transplantation von Wright, Mathew, Chandrakasan, Shanmuganathan, Okou, David T., Yin, Hong, Jurickova, Ingrid, Denson, Lee A., Kugathasan, Subra

Volltext

Transethnic analysis of the human leukocyte antigen region for ulcerative colitis reveals not only shared but also ethnicity-specific disease associations von Degenhardt, Frauke, Mayr, Gabriele, Wendorff, Mareike, Boucher, Gabrielle, Ellinghaus, Eva, Ellinghaus, David, ElAbd, Hesham, Rosati, Elisa, Hübenthal, Matthias, Juzenas, Simonas, Abedian, Shifteh, Vahedi, Homayon, Thelma, B K, Yang, Suk-Kyun, Ye, Byong Duk, Cheon, Jae Hee, Datta, Lisa Wu, Daryani, Naser Ebrahim, Ellul, Pierre, Esaki, Motohiro, Fuyuno, Yuta, McGovern, Dermot P B, Haritunians, Talin, Hong, Myhunghee, Juyal, Garima, Jung, Eun Suk, Kubo, Michiaki, Kugathasan, Subra, Lenz, Tobias L, Leslie, Stephen, Malekzadeh, Reza, Midha, Vandana, Motyer, Allan, Ng, Siew C, Okou, David T, Raychaudhuri, Soumya, Schembri, John, Schreiber, Stefan, Song, Kyuyoung, Sood, Ajit, Takahashi, Atsushi, Torres, Esther A, Umeno, Junji, Alizadeh, Behrooz Z, Weersma, Rinse K, Wong, Sunny H, Yamazaki, Keiko, Karlsen, Tom H, Rioux, John D, Brant, Steven R, Franke, Andre

Volltext

Meta-analysis confirms association between TNFA-G238A variant and JIA, and between PTPN22-C1858T variant and oligoarticular, RF-polyarticular and RF-positive polyarticular JIA von Kaalla, Merlyn J, Broadaway, K Alaine, Rohani-Pichavant, Mina, Conneely, Karen N, Whiting, April, Ponder, Lori, Okou, David T, Angeles-Han, Sheila, Rouster-Stevens, Kelly, Brown, Milton R, Vogler, Larry B, Jorde, Lynn B, Bohnsack, John F, Epstein, Michael P, Prahalad, Sampath

Volltext

Neutrophil GM-CSF signaling in inflammatory bowel disease patients is influenced by non-coding genetic variants von Venkateswaran, Suresh, Denson, Lee A., Jurickova, Ingrid, Dodd, Anne, Zwick, Michael E., Cutler, David J., Kugathasan, Subra, Okou, David T.

Volltext

Characterization of Genetic Loci That Affect Susceptibility to Inflammatory Bowel Diseases in African Americans von Huang, Chengrui, Haritunians, Talin, Okou, David T, Cutler, David J, Zwick, Michael E, Taylor, Kent D, Datta, Lisa W, Maranville, Joseph C, Liu, Zhenqiu, Ellis, Shannon, Chopra, Pankaj, Alexander, Jonathan S, Baldassano, Robert N, Cross, Raymond K, Dassopoulos, Themistocles, Dhere, Tanvi A, Duerr, Richard H, Hanson, John S, Hou, Jason K, Hussain, Sunny Z, Isaacs, Kim L, Kachelries, Kelly E, Kader, Howard, Kappelman, Michael D, Katz, Jeffrey, Kellermayer, Richard, Kirschner, Barbara S, Kuemmerle, John F, Kumar, Archana, Kwon, John H, Lazarev, Mark, Mannon, Peter, Moulton, Dedrick E, Osuntokun, Bankole O, Patel, Ashish, Rioux, John D, Rotter, Jerome I, Saeed, Shehzad, Scherl, Ellen J, Silverberg, Mark S, Silverman, Ann, Targan, Stephan R, Valentine, John F, Wang, Ming-Hsi, Simpson, Claire L, Bridges, S. Louis, Kimberly, Robert P, Rich, Stephen S, Cho, Judy H, Di Rienzo, Anna, Kao, Linda W.H, McGovern, Dermot P.B, Brant, Steven R, Kugathasan, Subra

Volltext

Exome Sequencing Identifies a Novel FOXP3 Mutation in a 2‐Generation Family With Inflammatory Bowel Disease von Okou, David T., Mondal, Kajari, Faubion, William A., Kobrynski, Lisa J., Denson, Lee A., Mulle, Jennifer G., Ramachandran, Dhanya, Xiong, Yuning, Svingen, Phyllis, Patel, Viren, Bose, Promita, Waters, Jon P., Prahalad, Sampath, Cutler, David J., Zwick, Michael E., Kugathasan, Subra

Volltext

Dissecting Allele Architecture of Early Onset IBD Using High-Density Genotyping von Cutler, David J, Zwick, Michael E, Okou, David T, Prahalad, Sampath, Walters, Thomas, Guthery, Stephen L, Dubinsky, Marla, Baldassano, Robert, Crandall, Wallace V, Rosh, Joel, Markowitz, James, Stephens, Michael, Kellermayer, Richard, Pfefferkorn, Marian, Heyman, Melvin B, LeLeiko, Neal, Mack, David, Moulton, Dedrick, Kappelman, Michael D, Kumar, Archana, Prince, Jarod, Bose, Promita, Mondal, Kajari, Ramachandran, Dhanya, Bohnsack, John F, Griffiths, Anne M, Haberman, Yael, Essers, Jonah, Thompson, Susan D, Aronow, Bruce, Keljo, David J, Hyams, Jeffrey S, Denson, Lee A, Kugathasan, Subra

Volltext

Microarray-based mutation detection in the dystrophin gene von Hegde, Madhuri R, Chin, Ephrem L.H, Mulle, Jennifer G, Okou, David T, Warren, Stephen T, Zwick, Michael E

Volltext

Common NOD2 risk variants in African Americans with Crohn's disease are due exclusively to recent Caucasian admixture von Adeyanju, Oloruntosin, Okou, David T., Huang, Clifton, Kumar, Archana, Sauer, Cary, Galloway, Courtney, Prasad, Mahadev, Waters, Jon, Cutler, David J., Zwick, Michael E., Dhere, Tanvi, Kugathasan, Subra

Volltext

387 Immunochip Implicates Multiple Genetic Loci for African American IBD Including HLA-DRB11502 for UC, NOD2, PTGER4, IL23R, LZKF3 and STAT5A/STAT3 for CD and Several Regions of Si... von Brant, Steven R, Huang, Chengrui, Haritunians, Talin, Okou, David T, Cutler, David J, Zwick, Michael E, Datta, Lisa W, Taylor, Kent D, Rotter, Jerome I, Bridges, S.L, Kimberly, Robert P, Rich, Stephan S, McGovern, Dermot, Kugathasan, Subra

Volltext