Single-Stranded DNA Mimicry in the p53 Transactivation Domain Interaction with Replication Protein A von Elena Bochkareva, Lilia Kaustov, Ayeda Ayed, Gwan-Su Yi, Lu, Ying, Pineda-Lucena, Antonio, Jack C. C. Liao, Andrei L. Okorokov, Milner, Jo, Arrowsmith, Cheryl H., Alexey Bochkarev

Volltext

DNA damage is able to induce senescence in tumor cells in vitro and in vivo von TE POELE, Robert H, OKOROKOV, Andrei L, JARDINE, Lesley, CUMMINGS, Jeffrey, JOEL, Simon P

Volltext

Novel Allosteric Mechanism of Dual p53/MDM2 and p53/MDM4 Inhibition by a Small Molecule von Grinkevich, Vera V, Vema, Aparna, Fawkner, Karin, Issaeva, Natalia, Andreotti, Virginia, Dickinson, Eleanor R, Hedström, Elisabeth, Spinnler, Clemens, Inga, Alberto, Larsson, Lars-Gunnar, Karlén, Anders, Wilhelm, Margareta, Barran, Perdita E, Okorokov, Andrei L, Selivanova, Galina, Zawacka-Pankau, Joanna E

Volltext

The structure of p53 tumour suppressor protein reveals the basis for its functional plasticity von Okorokov, Andrei L, Sherman, Michael B, Plisson, Celia, Grinkevich, Vera, Sigmundsson, Kristmundur, Selivanova, Galina, Milner, Jo, Orlova, Elena V

Volltext

The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage von Okorokov, AL, Rubbi, C P, Metcalfe, S, Milner, J

Volltext

The interaction of p53 with the nuclear matrix is mediated by F-actin and modulated by DNA damage von OKOROKOV, Andrei L, RUBBI, Carlos P, METCALFE, Su, MILNER, Jo

Volltext

Molecular structure of human geminin von Williams, Gareth H, Okorokov, Andrei L, Orlova, Elena V, Kingsbury, Sarah R, Bagneris, Claire, Gohlke, Ulrich, Stoeber, Kai

Volltext

Effect of wild-type, S15D and R175H p53 proteins on DNA end joining in vitro: potential mechanism of DNA double-strand break repair modulation von Okorokov, Andrei L., Warnock, Lorna, Milner, Jo

Volltext

An ATP/ADP-Dependent Molecular Switch Regulates the Stability of p53-DNA Complexes von Okorokov, Andrei L., Milner, Jo

Volltext

p53 binds the nuclear matrix in normal cells : binding involves the proline-rich domain of p53 and increases following genotoxic stress von MING JIANG, AXE, Tracy, HOLGATE, Robert, RUBBI, Carlos P, OKOROKOV, Andrei L, MEE, Trevor, MILNER, Jo

Volltext

Induced N- and C-terminal cleavage of p53: a core fragment of p53, generated by interaction with damaged DNA, promotes cleavage of the N-terminus of full-length p53, whereas ssDNA... von Okorokov, Andrei L., Ponchel, Frederique, Milner, Jo

Volltext

RNA synthesis block by 5, 6-dichloro-1-beta-D-ribofuranosylbenzimidazole (DRB) triggers p53-dependent apoptosis in human colon carcinoma cells von te Poele, R H, Okorokov, A L, Joel, S P

Volltext

Wild-type p53 protein shows calcium-dependent binding to F-actin von METCALFE, S, WEEDS, A, OKOROKOV, A. L, MILNER, J, COCKMAN, M, POPE, B

Volltext

Human Topoisomerase IIα and IIβ Interact with the C-Terminal Region of p53 von Cowell, Ian G., Okorokov, Andrei L., Cutts, Sarah A., Padget, Kay, Bell, Margaret, Milner, Jo, Austin, Caroline A.

Volltext

Proteolytic cleavage of p53 mutants in response to mismatched DNA von Mee, T, Okorokov, A L, Metcalfe, S, Milner, J

Volltext

Tools for analysis and conditional deletion of subsets of sensory neurons [version 1; peer review: 4 approved] von Santana-Varela, S, Bogdanov, YD, Gossage, SJ, Okorokov, AL, Li, S, de Clauser, L, Alves-Simoes, M, Sexton, JE, Iseppon, F, Luiz, AP, Zhao, J, Wood, JN, Cox, JJ

Volltext bestellen

Sensory neuron–derived NaV1.7 contributes to dorsal horn neuron excitability von Alles, SRA, Nascimento, F, Luján, R, Luiz, AP, Millet, Q, Bangash, MA, Santana-Varela, S, Zhou, X, Cox, JJ, Okorokov, AL, Beato, M, Zhao, J, Wood, JN

Volltext bestellen

p53 controls CDC7 levels to reinforce G1 cell cycle arrest upon genotoxic stress von Tudzarova, S, Mulholland, P, Dey, A, Stoeber, K, Okorokov, AL, Williams, GH

Volltext bestellen

Two p53 tetramers bind one consensus DNA response element von Kearns, S, Lurz, R, Orlova, EV, Okorokov, AL

Volltext bestellen

The structure of substrate-free microbial ribonuclease binase and of its complexes with 3′GMP and sulfate ions von Polyakov, K. M., Lebedev, A. A., Okorokov, A. L., Panov, K. I., Schulga, A. A., Pavlovsky, A. G., Karpeisky, M. Ya, Dodson, G. G.

Volltext