A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and Neisseria meningitidis outer membrane vesicles von Santana-Mederos, Darielys, Perez-Nicado, Rocmira, Climent, Yanet, Rodriguez, Laura, Ramirez, Belinda Sanchez, Perez-Rodriguez, Sonia, Rodriguez, Meybi, Labrada, Claudia, Hernandez, Tays, Diaz, Marianniz, Orosa, Ivette, Ramirez, Ubel, Oliva, Reynaldo, Garrido, Raine, Cardoso, Felix, Landys, Mario, Martinez, Roselyn, Gonzalez, Humberto, Hernandez, Tamara, Ochoa-Azze, Rolando, Perez, Jose L, Enriquez, Juliet, Gonzalez, Nibaldo, Infante, Yenicet, Espinosa, Luis A, Ramos, Yassel, González, Luis Javier, Valenzuela, Carmen, Casadesus, Ana Victoria, Fernandez, Briandy, Rojas, Gertrudis, Pérez-Massón, Beatriz, Tundidor, Yaima, Bermudez, Ernesto, Plasencia, Claudia A, Boggiano, Tammy, Ojito, Eduardo, Chiodo, Fabrizio, Fernandez, Sonsire, Paquet, Françoise, Fang, Cheng, Chen, Guang-Wu, Rivera, Daniel G, Valdes-Balbin, Yury, Garcia-Rivera, Dagmar, Verez Bencomo, Vicente

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Development of a scalable single process for producing SARS-CoV-2 RBD monomer and dimer vaccine antigens von Boggiano-Ayo, Tammy, Palacios-Oliva, Julio, Lozada-Chang, Sumlai, Relova-Hernandez, Ernesto, Gomez-Perez, Jose, Oliva, Gonzalo, Hernandez, Lourdes, Bueno-Soler, Alexi, Montes de Oca, Daidee, Mora, Osvaldo, Machado-Santisteban, Roberto, Perez-Martinez, Dayana, Perez-Masson, Beatriz, Cabrera Infante, Yanelys, Calzadilla-Rosado, Lisandra, Ramirez, Yaima, Aymed-Garcia, Judey, Ruiz-Ramirez, Ingrid, Romero, Yamile, Gomez, Tania, Espinosa, Luis A., Gonzalez, Luis Javier, Cabrales, Annia, Guirola, Osmany, de la Luz, Kathya Rashida, Pi-Estopiñan, Franciscary, Sanchez-Ramirez, Belinda, Garcia-Rivera, Dagmar, Valdes-Balbin, Yuri, Rojas, Gertrudis, Leon-Monzon, Kalet, Ojito-Magaz, Eduardo, Hardy, Eugenio

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SARS-CoV‑2 RBD-Tetanus Toxoid Conjugate Vaccine Induces a Strong Neutralizing Immunity in Preclinical Studies von Valdes-Balbin, Yury, Santana-Mederos, Darielys, Quintero, Lauren, Fernández, Sonsire, Rodriguez, Laura, Sanchez Ramirez, Belinda, Perez-Nicado, Rocmira, Acosta, Claudia, Méndez, Yanira, Ricardo, Manuel G, Hernandez, Tays, Bergado, Gretchen, Pi, Franciscary, Valdes, Annet, Carmenate, Tania, Ramirez, Ubel, Oliva, Reinaldo, Soubal, Jean-Pierre, Garrido, Raine, Cardoso, Felix, Landys, Mario, Gonzalez, Humberto, Farinas, Mildrey, Enriquez, Juliet, Noa, Enrique, Suarez, Anamary, Fang, Cheng, Espinosa, Luis A, Ramos, Yassel, González, Luis Javier, Climent, Yanet, Rojas, Gertrudis, Relova-Hernández, Ernesto, Cabrera Infante, Yanelys, Losada, Sum Lai, Boggiano, Tammy, Ojito, Eduardo, León, Kalet, Chiodo, Fabrizio, Paquet, Françoise, Chen, Guang-Wu, Rivera, Daniel G, Garcia-Rivera, Dagmar, Verez Bencomo, Vicente

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Aplicación del Análisis de Componentes Principales en el proceso de purificación de un biofármaco von Osvaldo Gozá León, Marí Fernández Águila, Rosa Haydee Rodríguez Garcel, Eduardo Ojito Magaz

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Visión de la innovación en un centro cubano de la biotecnología aplicada a la salud von Delgado Fernández, Mercedes, Lage Dávila, Agustín, Ojito Magaz, Eduardo, Espinosa Valdés, Mayra M., Arias Ormaza, Miguel Ángel

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A COVID-19 vaccine candidate composed of the SARS-CoV-2 RBD dimer and outer membrane vesicles von Santana-Mederos, Darielys, Perez-Nicado, Rocmira, Climent, Yanet, Rodriguez, Laura, Ramirez, Belinda Sanchez, Perez-Rodriguez, Sonia, Rodriguez, Meybi, Labrada, Claudia, Hernandez, Tays, Diaz, Marianniz, Orosa, Ivette, Ramirez, Ubel, Oliva, Reynaldo, Garrido, Raine, Cardoso, Felix, Landys, Mario, Martinez, Roselyn, Gonzalez, Humberto, Hernandez, Tamara, Ochoa-Azze, Rolando, Perez, Jose L, Enriquez, Juliet, Gonzalez, Nibaldo, Infante, Yenicet, Espinosa, Luis A, Ramos, Yassel, González, Luis Javier, Valenzuela, Carmen, Casadesus, Ana Victoria, Fernandez, Briandy, Rojas, Gertrudis, Pérez-Massón, Beatriz, Tundidor, Yaima, Bermudez, Ernesto, Plasencia, Claudia A, Boggiano, Tammy, Ojito, Eduardo, Chiodo, Fabrizio, Fernandez, Sonsire, Paquet, Françoise, Fang, Cheng, Chen, Guang-Wu, Rivera, Daniel G, Valdes-Balbin, Yury, Garcia-Rivera, Dagmar, Verez Bencomo, Vicente

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Safety and immunogenicity of anti-SARS-CoV-2 heterologous scheme with SOBERANA 02 and SOBERANA Plus vaccines: Phase IIb clinical trial in adults von Toledo-Romani, María Eugenia, García-Carmenate, Mayra, Verdecia-Sánchez, Leslyhana, Pérez-Rodríguez, Suzel, Rodriguez-González, Meybis, Valenzuela-Silva, Carmen, Paredes-Moreno, Beatriz, Sanchez-Ramirez, Belinda, González-Mugica, Raúl, Hernández-Garcia, Tays, Orosa-Vázquez, Ivette, Díaz-Hernández, Marianniz, Pérez-Guevara, María Teresa, Enriquez-Puertas, Juliet, Noa-Romero, Enrique, Palenzuela-Diaz, Ariel, Baro-Roman, Gerardo, Mendoza-Hernández, Ivis, Muñoz, Yaima, Gómez-Maceo, Yanet, Santos-Vega, Bertha Leysi, Fernandez-Castillo, Sonsire, Climent-Ruiz, Yanet, Rodríguez-Noda, Laura, Santana-Mederos, Darielys, García-Vega, Yanelda, Chen, Guang-Wu, Doroud, Delaram, Biglari, Alireza, Boggiano-Ayo, Tammy, Valdés-Balbín, Yury, Rivera, Daniel G., García-Rivera, Dagmar, Vérez-Bencomo, Vicente, Cubas-Curbelo, Mailin, Rodríguez-Castillo, Pedro Gabriel, Acevedo-Martínez, Yosmel, Estoque-Cabrera, Solangel, Ávila-Cabreja, José Alejandro, Alfaro-Guzmán, Ainadis, Zulueta-Pérez, Lilian, Espino-Rojas, Niurka Tamara, Medinas-Santos, Gloria Margarita, Sarda-Rodriguez, Ileana Luisa, Acosta-Martinez, Mario Alejandro, Reyes-Matienzo, Radamet, Coviella-Artime, José Manuel, Morffi-Cinta, Irania, Martínez-Pérez, Marisel, Valera-Fernández, Rodrigo, Garcés-Hechavarría, Aniurka, Martínez-Bedoya, Dayle, Garrido-Arteaga, Raine, Cardoso-SanJorge, Félix, Ramírez-Gonzalez, Ubel, Quintero-Moreno, Lauren, Ontivero-Pino, Ivis, Martínez-Rivera, Roselyn, Guillén-Obregón, Berta, Lora-García, Janet, Medina-Nápoles, Maite, Espi-Ávila, Jennifer, Fontanies-Fernández, Marcos, Domínguez-Pentón, Yeney Regla, Bergado-Baez, Gretchen, Pi-Estopiñán, Franciscary, Ojito-Magaz, Eduardo, Rodríguez, Misladys, Cruz-Sui, Otto, García-Montero, Majela, Dubed-Echevarría, Marta, García-López, Elena, Galano-Frutos, Evelyn, Perez-Perez, Alina, Morales-Ruano, Susana, Brito-Pascual, Idalmis, Amoroto, Maité, Arteaga-García, Amaylid

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Long-Term CB.Hep-1 Monoclonal Antibody Production in a Single-Use Bioreactor on a Rocker Platform with Serum- and Protein-Free Media von Valdés, Rodolfo, Galván, Alberto, González, Marcos, Aragón, Hasel, Hernández, Daily, Padilla, Sigifredo, Gómez, Leonardo, Gailán, David, Villegas, Yanet, Tamayo, Andrés, Pérez, Adelma, Pérez, Bárbara, Lao, Maylín, Calvo, Yodelis, Fernández, Aneet, Lee, Lianys, Suarez, Jania, García, Judey, Ojito, Eduardo

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Uso de composiciones vacunales que comprenden un dominio de unión al receptor del virus sars-cov-2 von Rolando OCHOA AZZE, Delia Esther PORTO GONZÁLEZ, Belinda SÁNCHEZ RAMÍREZ, Marta DUBED ECHEVERRÍA, Humberto GONZÁLEZ RODRÍGUEZ, Vicente Guillermo VEREZ BENCOMO, Kalet LEÓN MONZÓN, Arturo CHANG MONTEAGUDO, Yanet CLIMENT RUIZ, Dagmar GARCÍA RIVERA, Mireida RODRÍGUEZ ACOSTA, Mariannis DÍAZ HERNÁNDEZ, Eduardo OJITO MAGAZ, Ivette OROSA VAZQUEZ, Consuelo Milagro MACIAS ABRAHAM, Yury VALDÉS BALBÍN

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Conjugados covalentes del dominio de unión al receptor del virus sars-cov-2; proteína portadora; composiciones vacunales von Sonsire FERNÁNDEZ CASTILLO, Manuel GARCÍA RICARDO, Tammy BOGGIANO AYO, Belinda SÁNCHEZ RAMÍREZ, Darielys SANTANA MEDEROS, Reynaldo OLIVA HERNÁNDEZ, Daniel GARCÍA RIVERA, Vicente Guillermo VEREZ BENCOMO, Ubel Jesús RAMÍREZ GONZÁLEZ, Laura Marta RODRÍGUEZ NODA, Dagmar GARCÍA RIVERA, Eduardo OJITO MAGAZ, Yury VALDÉS BALBÍN

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Composiciones vacunales contra el virus sars-cov-2 basadas en un dímero del dominio de unión von Sonsire FERNÁNDEZ CASTILLO, Rocmira PÉREZ NICADO, Tammy BOGGIANO AYO, Belinda SÁNCHEZ RAMÍREZ, Reynaldo OLIVA HERNÁNDEZ, Humberto GONZÁLEZ RODRÍGUEZ, Guang Wu CHEN, Vicente Guillermo VEREZ BENCOMO, Yanet CLIMENT RUIZ, Ubel Jesús RAMÍREZ GONZÁLEZ, Laura Marta RODRÍGUEZ NODA, Dagmar GARCÍA RIVERA, Eduardo OJITO MAGAZ, Mario Landys CHOVEL CUERVO, Yury VALDÉS BALBÍN

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USE OF VACCINE COMPOSITIONS BASED ON SARS-COV-2 RECEPTOR BINDING DOMAIN IN DELIVERING PROTECTIVE IMMUNITY von Milagro, Consuelo, Chang Monteagudo, Arturo, Rodríguez Acosta, Mireida, Díaz Hernández, Mariannia, Orasa Vázquez, Ivette, Ojito Magaz, Eduardo, Ochoa Azze, Rolando, Climent Ruiz, Yanet, Valdés Balbín, Yury, León Monzón, Kalet, Porto González, Delia Esther, GarcÍa Rivera, Dagmar, Sánchez Ramírez, Belinda, Verez Bencomo, Vicente Guillermo, González Rodríguez, Humberto, Dubed Echeverría, Marta

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CONJUGADO COVALENTE, COMPOSIÇÃO DE VACINA, PROCEDIMENTO PARA A PREPARAÇÃO DO CONJUGADO COVALENTE, E, USO DA COMPOSIÇÃO DE VACINA von BELINDA SÁNCHEZ RAMÍREZ, DANIEL GARCÍA RIVERA, LAURA MARTA RODRÍGUEZ NODA, VICENTE GUILLERMO VEREZ BENCOMO, SONSIRE FERNÁNDEZ CASTILLO, TAMMY BOGGIANO AYO, UBEL JESÚS RAMÍREZ GONZÁLEZ, DAGMAR GARCÍA RIVERA, EDUARDO OJITO MAGAZ, MANUEL GARCÍA RICARDO, YURY VALDÉS BALBÍN, DARIELYS SANTANA MEDEROS, REYNALDO OLIVA HERNÁNDEZ

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COMPOSIÇÃO DE VACINA QUE INDUZ UMA RESPOSTA IMUNE CONTRA O VÍRUS SARS-COV-2, PROCEDIMENTO PARA OBTER AS OMVS, E, USO DA COMPOSIÇÃO DE VACINA von BELINDA SÁNCHEZ RAMÍREZ, VICENTE GUILLERMO VEREZ BENCOMO, LAURA MARTA RODRÍGUEZ NODA, SONSIRE FERNÁNDEZ CASTILLO, TAMMY BOGGIANO AYO, HUMBERTO GONZÁLEZ RODRÍGUEZ, MARIO LANDYS CHOVEL CUERVO, UBEL JESÚS RAMÍREZ GONZÁLEZ, DAGMAR GARCÍA RIVERA, EDUARDO OJITO MAGAZ, YURY VALDÉS BALBÍN, YANET CLIMENT RUIZ, GUANG WU CHEN, ROCMIRA PÉREZ NICADO, REYNALDO OLIVA HERNÁNDEZ

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COVALENT CONJUGATES OF THE SARS-COV-2 RECEPTOR-BINDING DOMAIN AND A CARRIER PROTEIN AND VACCINE COMPOSITIONS THAT CONTAIN THEM von García Ricardo, Manuel, García Rivera, Daniel, Ojito Magaz, Eduardo, Boggiano Ayo, Tammy, García Rivera, Dagmar, Valdés Balbín, Yury, Ramírez González, Ubel Jesús, Oliva Hernández, Reynaldo, Santana Mederos, Darielys, Rodríguez Noda, Laura Marta, Fernández Castillo, Sonsire, Sánchez Ramírez, Belinda, Verez Bencomo, Vicente Guillermo

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USE OF VACCINE COMPOSITIONS BASED ON SARS-COV-2 RECEPTOR BINDING DOMAIN IN DELIVERING PROTECTIVE IMMUNITY von CLIMENT RUIZ, Yanet, GARCÍA RIVERA, Dagmar, OJITO MAGAZ, Eduardo, SÁNCHEZ RAMÍREZ, Belinda, VEREZ BENCOMO, Vicente Guillermo, PORTO GONZÁLEZ, Delia Esther, OROSA VAZQUEZ, Ivette, RODRÍGUEZ ACOSTA, Mireida, CHANG MONTEAGUDO, Arturo, DUBED ECHEVERRÍA, Marta, OCHOA AZZE, Rolando, MACIAS ABRAHAM, Consuelo Milagro, DÍAZ HERNÁNDEZ, Mariannis, LEÓN MONZÓN, Kalet, VALDÉS BALBÍN, Yury, GONZÁLEZ RODRÍGUEZ, Humberto

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COMPOSITIONS OF SARS-COV-2 VACCINES BASED ON THE RECEPTOR BINDING DOMAIN, EXPRESSED AS A DIMER, AND THE OUTER MEMBRANE VESICLE OF MENINGOCOCCAL GROUP B BACTERIA von Chovel Cuervo, Mario Landys, Ojito Magaz, Eduardo, Boggiano Ayo, Tammy, García Rivera, Dagmar, Climent Ruiz, Yanet, Valdés Balbín, Yury, Ramírez González, Ubel Jesús, Oliva Hernández, Reynaldo, Pérez Nicado, Rocmira, Rodríguez Noda, Laura Marta, Fernández Castillo, Sonsire, Humberto, González Rodríguez, Sánchez Ramírez, Belinda, Verez Bencomo, Vicente Guillermo, Chen, Guang Wu

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COVALENT CONJUGATES OF THE SARS-COV-2 RECEPTOR-BINDING DOMAIN AND A CARRIER PROTEIN AND VACCINE COMPOSITIONS THAT CONTAIN THEM von GARCÍA RIVERA, Dagmar, OJITO MAGAZ, Eduardo, SÁNCHEZ RAMÍREZ, Belinda, RAMÍREZ GONZÁLEZ, Ubel Jesús, BOGGIANO AYO, Tammy, OLIVA HERNÁNDEZ, Reynaldo, SANTANA MEDEROS, Darielys, FERNÁNDEZ CASTILLO, Sonsire, VEREZ BENCOMO, Vicente Guillermo, GARCÍA RIVERA, Daniel, RODRÍGUEZ NODA, Laura Marta, VALDÉS BALBÍN, Yury, GARCÍA RICARDO, Manuel

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USE OF VACCINE COMPOSITIONS BASED ON SARS-COV-2 RECEPTOR BINDING DOMAIN IN DELIVERING PROTECTIVE IMMUNITY von CLIMENT RUIZ, Yanet, GARCÍA RIVERA, Dagmar, OJITO MAGAZ, Eduardo, SÁNCHEZ RAMÍREZ, Belinda, VEREZ BENCOMO, Vicente Guillermo, PORTO GONZÁLEZ, Delia Esther, OROSA VAZQUEZ, Ivette, RODRÍGUEZ ACOSTA, Mireida, CHANG MONTEAGUDO, Arturo, DUBED ECHEVERRÍA, Marta, OCHOA AZZE, Rolando, MACIAS ABRAHAM, Consuelo Milagro, DÍAZ HERNÁNDEZ, Mariannis, LEÓN MONZÓN, Kalet, VALDÉS BALBÍN, Yury, GONZÁLEZ RODRÍGUEZ, Humberto

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COMPOSITIONS OF SARS-COV-2 VACCINES BASED ON THE RECEPTOR BINDING DOMAIN, EXPRESSED AS A DIMER, AND THE OUTER MEMBRANE VESICLE OF MENINGOCOCCAL GROUP B BACTERIA von CLIMENT RUIZ, Yanet, GARCÍA RIVERA, Dagmar, OJITO MAGAZ, Eduardo, SÁNCHEZ RAMÍREZ, Belinda, RAMÍREZ GONZÁLEZ, Ubel Jesús, BOGGIANO AYO, Tammy, OLIVA HERNÁNDEZ, Reynaldo, VEREZ BENCOMO, Vicente Guillermo, FERNÁNDEZ CASTILLO, Sonsire, PÉREZ NICADO, Rocmira, RODRÍGUEZ NODA, Laura Marta, CHEN, Guang Wu, VALDÉS BALBÍN, Yury, GONZÁLEZ RODRÍGUEZ, Humberto, CHOVEL CUERVO, Mario Landys

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