DIS3 : The Enigmatic Gene in Multiple Myeloma von Ohguchi, Yasuyo, Ohguchi, Hiroto

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Diverse Functions of KDM5 in Cancer: Transcriptional Repressor or Activator? von Ohguchi, Yasuyo, Ohguchi, Hiroto

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The JAK-STAT pathway regulates CD38 on myeloma cells in the bone marrow microenvironment: therapeutic implications von Ogiya, Daisuke, Liu, Jiye, Ohguchi, Hiroto, Kurata, Keiji, Samur, Mehmet K., Tai, Yu-Tzu, Adamia, Sophia, Ando, Kiyoshi, Hideshima, Teru, Anderson, Kenneth C.

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Downregulation of ERG and FLI1 expression in endothelial cells triggers endothelial-to-mesenchymal transition von Nagai, Nao, Ohguchi, Hiroto, Nakaki, Ryo, Matsumura, Yoshihiro, Kanki, Yasuharu, Sakai, Juro, Aburatani, Hiroyuki, Minami, Takashi

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Inflammation-driven senescence-associated secretory phenotype in cancer-associated fibroblasts enhances peritoneal dissemination von Yasuda, Tadahito, Koiwa, Mayu, Yonemura, Atsuko, Miyake, Keisuke, Kariya, Ryusho, Kubota, Sho, Yokomizo-Nakano, Takako, Yasuda-Yoshihara, Noriko, Uchihara, Tomoyuki, Itoyama, Rumi, Bu, Luke, Fu, Lingfeng, Arima, Kota, Izumi, Daisuke, Iwagami, Shiro, Eto, Kojiro, Iwatsuki, Masaaki, Baba, Yoshifumi, Yoshida, Naoya, Ohguchi, Hiroto, Okada, Seiji, Matsusaki, Keisuke, Sashida, Goro, Takahashi, Akiko, Tan, Patrick, Baba, Hideo, Ishimoto, Takatsugu

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Lenalidomide Enhances Immune Checkpoint Blockade-Induced Immune Response in Multiple Myeloma von Görgün, Güllü, Samur, Mehmet K, Cowens, Kristen B, Paula, Steven, Bianchi, Giada, Anderson, Julie E, White, Randie E, Singh, Ahaana, Ohguchi, Hiroto, Suzuki, Rikio, Kikuchi, Shohei, Harada, Takeshi, Hideshima, Teru, Tai, Yu-Tzu, Laubach, Jacob P, Raje, Noopur, Magrangeas, Florence, Minvielle, Stephane, Avet-Loiseau, Herve, Munshi, Nikhil C, Dorfman, David M, Richardson, Paul G, Anderson, Kenneth C

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The biological significance of histone modifiers in multiple myeloma: clinical applications von Ohguchi, Hiroto, Hideshima, Teru, Anderson, Kenneth C.

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Ribonucleotide Reductase Catalytic Subunit M1 (RRM1) as a Novel Therapeutic Target in Multiple Myeloma von Sagawa, Morihiko, Ohguchi, Hiroto, Harada, Takeshi, Samur, Mehmet K, Tai, Yu-Tzu, Munshi, Nikhil C, Kizaki, Masahiro, Hideshima, Teru, Anderson, Kenneth C

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Discovery of selective small-molecule HDAC6 inhibitor for overcoming proteasome inhibitor resistance in multiple myeloma von Hideshima, Teru, Qi, Jun, Paranal, Ronald M., Tang, Weiping, Greenberg, Edward, West, Nathan, Colling, Meaghan E., Estiu, Guillermina, Mazitschek, Ralph, Perry, Jennifer A., Ohguchi, Hiroto, Cottini, Francesca, Mimura, Naoya, Görgün, Güllü, Tai, Yu-Tzu, Richardson, Paul G., Carrasco, Ruben D., Wiest, Olaf, Schreiber, Stuart L., Anderson, Kenneth C., Bradner, James E.

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Evidence for a role of the histone deacetylase SIRT6 in DNA damage response of multiple myeloma cells von Cea, Michele, Cagnetta, Antonia, Adamia, Sophia, Acharya, Chirag, Tai, Yu-Tzu, Fulciniti, Mariateresa, Ohguchi, Hiroto, Munshi, Aditya, Acharya, Prakrati, Bhasin, Manoj K., Zhong, Lei, Carrasco, Ruben, Monacelli, Fiammetta, Ballestrero, Alberto, Richardson, Paul, Gobbi, Marco, Lemoli, Roberto M., Munshi, Nikhil, Hideshima, Teru, Nencioni, Alessio, Chauhan, Dharminder, Anderson, Kenneth C.

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Author Correction: The biological significance of histone modifiers in multiple myeloma: clinical applications von Ohguchi, Hiroto, Hideshima, Teru, Anderson, Kenneth C.

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The KDM3A–KLF2–IRF4 axis maintains myeloma cell survival von Ohguchi, Hiroto, Hideshima, Teru, Bhasin, Manoj K., Gorgun, Gullu T., Santo, Loredana, Cea, Michele, Samur, Mehmet K., Mimura, Naoya, Suzuki, Rikio, Tai, Yu-Tzu, Carrasco, Ruben D., Raje, Noopur, Richardson, Paul G., Munshi, Nikhil C., Harigae, Hideo, Sanda, Takaomi, Sakai, Juro, Anderson, Kenneth C.

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Selective and Potent Akt Inhibition Triggers Anti-Myeloma Activities and Enhances Fatal Endoplasmic Reticulum Stress Induced by Proteasome Inhibition von MIMURA, Naoya, HIDESHIMA, Teru, CIRSTEA, Diana, GORGUN, Gullu, MINAMI, Jiro, TAI, Yu-Tzu, RICHARDSON, Paul G, UTSUGI, Teruhiro, IWAMA, Atsushi, ANDERSON, Kenneth C, SHIMOMURA, Toshiyasu, SUZUKI, Rikio, OHGUCHI, Hiroto, RIZQ, Ola, KIKUCHI, Shohei, YOSHIDA, Yasuhiro, COTTINI, Francesca, JAKUBIKOVA, Jana

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p53-related protein kinase confers poor prognosis and represents a novel therapeutic target in multiple myeloma von Hideshima, Teru, Cottini, Francesca, Nozawa, Yoshihisa, Seo, Hyuk-Soo, Ohguchi, Hiroto, Samur, Mehmet K., Cirstea, Diana, Mimura, Naoya, Iwasawa, Yoshikazu, Richardson, Paul G., Munshi, Nikhil C., Chauhan, Dharminder, Massefski, Walter, Utsugi, Teruhiro, Dhe-Paganon, Sirano, Anderson, Kenneth C.

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Protocol for transcriptomic and epigenomic analyses of tip-like endothelial cells using scRNA-seq and ChIP-seq von Funasaki, Shintaro, Miyamura, Yuri, Kamei, Shunsuke, Rahman, Akhinur, Yamazaki, Masaya, Usuki, Shingo, Yasunaga, Keiichiro, Satou, Yorifumi, Ohguchi, Hiroto, Minami, Takashi

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IDIS3/I: The Enigmatic Gene in Multiple Myeloma von Ohguchi, Yasuyo, Ohguchi, Hiroto

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Increased CSN5 expression enhances the sensitivity to lenalidomide in multiple myeloma cells von Yamamoto, Takumi, Furukawa, Arisu, Zhou, Yue, Kono, Nobuaki, Kitajima, Shojiro, Ohguchi, Hiroto, Kawano, Yawara, Ito, Shingo, Araki, Norie, Ohtsuki, Sumio, Masuda, Takeshi

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Blockade of XBP1 splicing by inhibition of IRE1α is a promising therapeutic option in multiple myeloma von Mimura, Naoya, Fulciniti, Mariateresa, Gorgun, Gullu, Tai, Yu-Tzu, Cirstea, Diana, Santo, Loredana, Hu, Yiguo, Fabre, Claire, Minami, Jiro, Ohguchi, Hiroto, Kiziltepe, Tanyel, Ikeda, Hiroshi, Kawano, Yutaka, French, Maureen, Blumenthal, Martina, Tam, Victor, Kertesz, Nathalie L., Malyankar, Uriel M., Hokenson, Mark, Pham, Tuan, Zeng, Qingping, Patterson, John B., Richardson, Paul G., Munshi, Nikhil C., Anderson, Kenneth C.

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Combination of a Selective HSP90α/β Inhibitor and a RAS-RAF-MEK-ERK Signaling Pathway Inhibitor Triggers Synergistic Cytotoxicity in Multiple Myeloma Cells von Suzuki, Rikio, Kikuchi, Shohei, Harada, Takeshi, Mimura, Naoya, Minami, Jiro, Ohguchi, Hiroto, Yoshida, Yasuhiro, Sagawa, Morihiko, Gorgun, Gullu, Cirstea, Diana, Cottini, Francesca, Jakubikova, Jana, Tai, Yu-Tzu, Chauhan, Dharminder, Richardson, Paul G, Munshi, Nikhil, Ando, Kiyoshi, Utsugi, Teruhiro, Hideshima, Teru, Anderson, Kenneth C

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Delineating the mTOR kinase pathway using a dual TORC1/2 inhibitor, AZD8055, in multiple myeloma von Cirstea, Diana, Santo, Loredana, Hideshima, Teru, Eda, Homare, Mishima, Yuko, Nemani, Neeharika, Mahindra, Anuj, Yee, Andrew, Gorgun, Gullu, Hu, Yiguo, Ohguchi, Hiroto, Suzuki, Rikio, Cottini, Francesca, Guichard, Sylvie M, Anderson, Kenneth C, Raje, Noopur

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