TRP channels as emerging targets for pain therapeutics von Broad, Lisa M, Mogg, Adrian J, Beattie, Ruth E, Ogden, Ann-Marie, Blanco, Maria-Jesus, Bleakman, David

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Phosphodiesterase 10A inhibitor, MP-10 (PF-2545920), produces greater induction of c-Fos in dopamine D2 neurons than in D1 neurons in the neostriatum von Wilson, Jonathan M., Ogden, Ann Marie L., Loomis, Sally, Gilmour, Gary, Baucum, Anthony J., Belecky-Adams, Teri L., Merchant, Kalpana M.

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GluK1 antagonists from 6-(tetrazolyl)phenyl decahydroisoquinoline derivatives: In vitro profile and in vivo analgesic efficacy von Martinez-Perez, Jose A., Iyengar, Smriti, Shannon, Harlan E., Bleakman, David, Alt, Andrew, Clawson, David K., Arnold, Brian M., Bell, Michael G., Bleisch, Thomas J., Castaño, Ana M., Del Prado, Miriam, Dominguez, Esteban, Escribano, Ana M., Filla, Sandra A., Ho, Ken H., Hudziak, Kevin J., Jones, Carrie K., Mateo, Ana, Mathes, Brian M., Mattiuz, Edward L., Ogden, Ann Marie L., Simmons, Rosa Maria A., Stack, Douglas R., Stratford, Robert E., Winter, Mark A., Wu, Zhipei, Ornstein, Paul L.

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GluK1 antagonists from 6-(carboxy)phenyl decahydroisoquinoline derivatives. SAR and evaluation of a prodrug strategy for oral efficacy in pain models von Martinez-Perez, Jose A., Iyengar, Smriti, Shannon, Harlan E., Bleakman, David, Alt, Andrew, Arnold, Brian M., Bell, Michael G., Bleisch, Thomas J., Castaño, Ana M., Del Prado, Miriam, Dominguez, Esteban, Escribano, Ana M., Filla, Sandra A., Ho, Ken H., Hudziak, Kevin J., Jones, Carrie K., Mateo, Ana, Mathes, Brian M., Mattiuz, Edward L., Ogden, Ann Marie L., Simmons, Rosa Maria A., Stack, Douglas R., Stratford, Robert E., Winter, Mark A., Wu, Zhipei, Ornstein, Paul L.

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Two Prodrugs of Potent and Selective GluR5 Kainate Receptor Antagonists Actives in Three Animal Models of Pain von Dominguez, Esteban, Iyengar, Smriti, Shannon, Harlan E, Bleakman, David, Alt, Andrew, Arnold, Brian M, Bell, Michael G, Bleisch, Thomas J, Buckmaster, Jennifer L, Castano, Ana M, Del Prado, Miriam, Escribano, Ana, Filla, Sandra A, Ho, Ken H, Hudziak, Kevin J, Jones, Carrie K, Martinez-Perez, Jose A, Mateo, Ana, Mathes, Brian M, Mattiuz, Edward L, Ogden, Ann Marie L, Simmons, Rosa Maria A, Stack, Douglas R, Stratford, Robert E, Winter, Mark A, Wu, Zhipei, Ornstein, Paul L

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Pharmacological characterization of a GluR6 kainate receptor in cultured hippocampal neurons von Bleakman, David, Ogden, Ann-Marie, Ornstein, Paul L, Hoo, Ken

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Pharmacological Modulation of GluK1 and GluK2 by NETO1, NETO2, and PSD95 von Li, Baolin, Rex, Elizabeth, Wang, He, Qian, Yuewei, Ogden, Ann Marie, Bleakman, David, Johnson, Kirk W

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Rapid down regulation of β-adrenoceptors by co-administration of desipramine and fluoxetine von Baron, Bruce M., Ogden, Ann-Marie, Siegel, Barry W., Stegeman, James, Ursillo, Richard C., Dudley, Mark W.

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Antagonists of GLUK5-containing kainate receptors prevent pilocarpine-induced limbic seizures von Smolders, Ilse, Bortolotto, Zuner A., Clarke, Vernon R. J., Warre, Ruth, Khan, Ghous M., O'Neill, Michael J., Ornstein, Paul L., Bleakman, David, Ogden, AnnMarie, Weiss, Brianne, Stables, James P., Ho, Ken H., Ebinger, Guy, Collingridge, Graham L., Lodge, David, Michotte, Yvette

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5-Aryl-3-(alkylthio)-4H-1,2,4-triazoles as selective antagonists of strychnine-induced convulsions and potential antispastic agents von Kane, John M, Staeger, Michael A, Dalton, Christopher R, Miller, Francis P, Dudley, Mark W, Ogden, Ann Marie L, Kehne, John H, Ketteler, Herbert J, McCloskey, Timothy C

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A novel synthesis of xanthines: support for a new binding mode for xanthines with respect to adenosine at adenosine receptors von Peet, Norton P, Lentz, Nelsen L, Meng, Elaine C, Dudley, Mark W, Ogden, Ann Marie L, Demeter, David A, Weintraub, Herschel J. R, Bey, Philippe

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Conformationally restrained, chiral (phenylisopropyl)amino-substituted pyrazolo[3,4-d]pyrimidines and purines with selectivity for adenosine A1 and A2 receptors von Peet, Norton P, Lentz, Nelsen L, Sunder, Shyam, Dudley, Mark W, Ogden, Ann Marie L

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In vitro and in vivo studies in rats with LY293558 suggest AMPA/kainate receptor blockade as a novel potential mechanism for the therapeutic treatment of anxiety disorders von ALT, Andrew, WEISS, Brianne, OGDEN, Ann Marie, XIA LI, GLEASON, Scott D, CALLIGARO, David O, BLEAKMAN, David, WITKIN, Jeffrey M

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Xanthines with C8 chiral substituents as potent and selective adenosine A1 antagonists von Peet, Norton P, Lentz, Nelsen L, Dudley, Mark W, Ogden, Ann Marie L, McCarty, Deborah R, Racke, Margaret M

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Two prodrugs of potent and selective GluR5 kainate receptor antagonists actives in three animal models of pain : 2005 American Chemical Society Award for Computers in Chemical and... von DOMINGUEZ, Esteban, IYENGAR, Smriti, DEL PRADO, Miriam, ESCRIBANO, Ana, FILLA, Sandra A, HO, Ken H, HUDZIAK, Kevin J, JONES, Carrie K, MARTINEZ-PEREZ, Jose A, MATEO, Ana, MATHES, Brian M, MATTIUZ, Edward L, SHANNON, Harlan E, OGDEN, Ann Marie L, SIMMONS, Rosa Maria A, STACK, Douglas R, STRATFORD, Robert E, WINTER, Mark A, ZHIPEI WU, ORNSTEIN, Paul L, BLEAKMAN, David, ALT, Andrew, ARNOLD, Brian M, BELL, Michael G, BLEISCH, Thomas J, BUCKMASTER, Jennifer L, CASTANO, Ana M

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Inflammatory Cytokines Enhance Muscarinic‐Mediated Arachidonic Acid Release Through p38 Mitogen‐Activated Protein Kinase in A2058 Cells von Wood, Michael W., Segal, Jeff A., Mark, Robert J., Ogden, Ann Marie, Felder, Christian C.

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Ethyl (3S,4aR,6S,8aR)-6-(4-Ethoxycar- bonylimidazol-1-ylmethyl)decahydroiso- quinoline-3-carboxylic Ester:  A Prodrug of a GluR5 Kainate Receptor Antagonist Active in Two Animal Mo... von Filla, Sandra A, Winter, Mark A, Johnson, Kirk W, Bleakman, David, Bell, Michael G, Bleisch, Thomas J, Castaño, Ana M, Clemens-Smith, Amy, del Prado, Miriam, Dieckman, Donna K, Dominguez, Esteban, Escribano, Ana, Ho, Ken H, Hudziak, Kevin J, Katofiasc, Mary A, Martinez-Perez, Jose A, Mateo, Ana, Mathes, Brian M, Mattiuz, Edward L, Ogden, Ann Marie L, Phebus, Lee A, Stack, Douglas R, Stratford, Robert E, Ornstein, Paul L

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Ethyl (3S, 4aR, 6S, 8aR)-6-(4-ethoxycarbonylimidazol-1-ylmethyl)decahydroisoquinoline-3-c arboxylic ester: A prodrug of a GluR5 kainate receptor antagonist active in two animal mod... von FILLA, Sandra A, WINTER, Mark A, DOMINGUEZ, Esteban, ESCRIBANO, Ana, HO, Ken H, HUDZIAK, Kevin J, KATOFIASC, Mary A, MARTINEZ-PEREZ, Jose A, MATEO, Ana, MATHES, Brian M, MATTIUZ, Edward L, OGDEN, Ann Marie L, JOHNSON, Kirk W, PHEBUS, Lee A, STACK, Douglas R, STRATFORD, Robert E, ORNSTEIN, Paul L, BLEAKMAN, David, BELL, Michael G, BLEISCH, Thomas J, CASTANO, Ana M, CLEMENS-SMITH, Amy, DEL PRADO, Miriam, DIECKMAN, Donna K

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MDL 27,531 selectively reverses strychnine‐induced seizures in mice von Kehne, John H., Kane, John M., Miller, Francis P., Ketteler, Herbert J., Braun, Donald L., Senyah, Yaw, Chaney, Stephen F., Abdallah, Abdulmuniem, Dudley, Mark W., Ogden, Ann Marie, Palfreyman, Michael G.

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A PSA SNP associates with cellular function and clinical outcome in men with prostate cancer von Srinivasan, Srilakshmi, Kryza, Thomas, Bock, Nathalie, Tse, Brian W. C., Sokolowski, Kamil A., Janaththani, Panchadsaram, Fernando, Achala, Moya, Leire, Stephens, Carson, Dong, Ying, Röhl, Joan, Alinezhad, Saeid, Vela, Ian, Perry-Keene, Joanna L., Buzacott, Katie, Nica, Robert, Gago-Dominguez, Manuela, Schleutker, Johanna, Maier, Christiane, Muir, Kenneth, Tangen, Catherine M., Gronberg, Henrik, Pashayan, Nora, Albanes, Demetrius, Wolk, Alicja, Stanford, Janet L., Berndt, Sonja I., Mucci, Lorelei A., Koutros, Stella, Cussenot, Olivier, Sorensen, Karina Dalsgaard, Grindedal, Eli Marie, Travis, Ruth C., Haiman, Christopher A., MacInnis, Robert J., Vega, Ana, Wiklund, Fredrik, Neal, David E., Kogevinas, Manolis, Penney, Kathryn L., Nordestgaard, Børge G., Brenner, Hermann, John, Esther M., Gamulin, Marija, Claessens, Frank, Melander, Olle, Dahlin, Anders, Stattin, Pär, Hallmans, Göran, Häggström, Christel, Johansson, Robert, Thysell, Elin, Rönn, Ann-Charlotte, Li, Weiqiang, Brown, Nigel, Dimeski, Goce, Shepherd, Benjamin, Dadaev, Tokhir, Brook, Mark N., Spurdle, Amanda B., Stenman, Ulf-Håkan, Koistinen, Hannu, Kote-Jarai, Zsofia, Klein, Robert J., Lilja, Hans, Ecker, Rupert C., Eeles, Rosalind, Clements, Judith, Batra, Jyotsna

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