Neurofilament levels are associated with blood–brain barrier integrity, lymphocyte extravasation, and risk factors following the first demyelinating event in multiple sclerosis von Uher, Tomas, McComb, Mason, Galkin, Shery, Srpova, Barbora, Oechtering, Johanna, Barro, Christian, Tyblova, Michaela, Bergsland, Niels, Krasensky, Jan, Dwyer, Michael, Havrdova, Eva Kubala, Posova, Helena, Vaneckova, Manuela, Zivadinov, Robert, Horakova, Dana, Kuhle, Jens, Ramanathan, Murali

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Severe Neuro-COVID is associated with peripheral immune signatures, autoimmunity and neurodegeneration: a prospective cross-sectional study von Etter, Manina M., Martins, Tomás A., Kulsvehagen, Laila, Pössnecker, Elisabeth, Duchemin, Wandrille, Hogan, Sabrina, Sanabria-Diaz, Gretel, Müller, Jannis, Chiappini, Alessio, Rychen, Jonathan, Eberhard, Noëmi, Guzman, Raphael, Mariani, Luigi, Melie-Garcia, Lester, Keller, Emanuela, Jelcic, Ilijas, Pargger, Hans, Siegemund, Martin, Kuhle, Jens, Oechtering, Johanna, Eich, Caroline, Tzankov, Alexandar, Matter, Matthias S., Uzun, Sarp, Yaldizli, Özgür, Lieb, Johanna M., Psychogios, Marios-Nikos, Leuzinger, Karoline, Hirsch, Hans H., Granziera, Cristina, Pröbstel, Anne-Katrin, Hutter, Gregor

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Serum GFAP and NfL as disease severity and prognostic biomarkers in patients with aquaporin-4 antibody-positive neuromyelitis optica spectrum disorder von Schindler, Patrick, Grittner, Ulrike, Oechtering, Johanna, Leppert, David, Siebert, Nadja, Duchow, Ankelien S., Oertel, Frederike C., Asseyer, Susanna, Kuchling, Joseph, Zimmermann, Hanna G., Brandt, Alexander U., Benkert, Pascal, Reindl, Markus, Jarius, Sven, Paul, Friedemann, Bellmann-Strobl, Judith, Kuhle, Jens, Ruprecht, Klemens

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Determination of CSF GFAP, CCN5, and vWF Levels Enhances the Diagnostic Accuracy of Clinically Defined MS From Non-MS Patients With CSF Oligoclonal Bands von Probert, Fay, Yeo, Tianrong, Zhou, Yifan, Sealey, Megan, Arora, Siddharth, Palace, Jacqueline, Claridge, Timothy D W, Hillenbrand, Rainer, Oechtering, Johanna, Kuhle, Jens, Leppert, David, Anthony, Daniel C

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Corrigendum: Determination of CSF GFAP, CCN5, and vWF levels enhances the diagnostic accuracy of clinically defined MS from non-MS patients with CSF oligoclonal bands von Probert, Fay, Yeo, Tianrong, Zhou, Yifan, Sealey, Megan, Arora, Siddharth, Palace, Jacqueline, Claridge, Timothy D W, Hillenbrand, Rainer, Oechtering, Johanna, Kuhle, Jens, Leppert, David, Anthony, Daniel C

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MultiSCRIPT-Cycle 1-a pragmatic trial embedded within the Swiss Multiple Sclerosis Cohort (SMSC) on neurofilament light chain monitoring to inform personalized treatment decisions... von Janiaud, Perrine, Zecca, Chiara, Salmen, Anke, Benkert, Pascal, Schädelin, Sabine, Orleth, Annette, Demuth, Lilian, Maceski, Aleksandra Maleska, Granziera, Cristina, Oechtering, Johanna, Leppert, David, Derfuss, Tobias, Achtnichts, Lutz, Findling, Oliver, Roth, Patrick, Lalive, Patrice, Uginet, Marjolaine, Müller, Stefanie, Pot, Caroline, Hoepner, Robert, Disanto, Giulio, Gobbi, Claudio, Rooshenas, Leila, Schwenkglenks, Matthias, Lambiris, Mark J, Kappos, Ludwig, Kuhle, Jens, Yaldizli, Özgür, Hemkens, Lars G

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Impact of complement activation on clinical outcomes in multiple sclerosis von Keller, Christian W., Oechtering, Johanna, Wiendl, Heinz, Kappos, Ludwig, Kuhle, Jens, Lünemann, Jan D.

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Serum neurofilament light chain for individual prognostication of disease activity in people with multiple sclerosis: a retrospective modelling and validation study von Benkert, Pascal, Meier, Stephanie, Schaedelin, Sabine, Manouchehrinia, Ali, Yaldizli, Özgür, Maceski, Aleksandra, Oechtering, Johanna, Achtnichts, Lutz, Conen, David, Derfuss, Tobias, Lalive, Patrice H, Mueller, Christian, Müller, Stefanie, Naegelin, Yvonne, Oksenberg, Jorge R, Pot, Caroline, Salmen, Anke, Willemse, Eline, Kockum, Ingrid, Blennow, Kaj, Zetterberg, Henrik, Gobbi, Claudio, Kappos, Ludwig, Wiendl, Heinz, Berger, Klaus, Sormani, Maria Pia, Granziera, Cristina, Piehl, Fredrik, Leppert, David, Kuhle, Jens, Aeschbacher, Stefanie, Barakovic, Muhamed, Buser, Andreas, Chan, Andrew, Disanto, Giulio, D'Souza, Marcus, Du Pasquier, Renaud, Findling, Oliver, Galbusera, Riccardo, Hrusovsky, Kevin, Khalil, Michael, Lorscheider, Johannes, Mathias, Amandine, Orleth, Annette, Radue, Ernst-Wilhelm, Rahmanzadeh, Reza, Sinnecker, Tim, Subramaniam, Suvitha, Vehoff, Jochen, Wellmann, Sven, Wuerfel, Jens, Zecca, Chiara

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Author response: Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis von Ruprecht, Klemens, Pfuhl, Catherina, Oechtering, Johanna

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Serum Glial Fibrillary Acidic Protein Compared With Neurofilament Light Chain as a Biomarker for Disease Progression in Multiple Sclerosis von Meier, Stephanie, Willemse, Eline A.J, Schaedelin, Sabine, Oechtering, Johanna, Lorscheider, Johannes, Melie-Garcia, Lester, Cagol, Alessandro, Barakovic, Muhamed, Galbusera, Riccardo, Subramaniam, Suvitha, Barro, Christian, Abdelhak, Ahmed, Thebault, Simon, Achtnichts, Lutz, Lalive, Patrice, Müller, Stefanie, Pot, Caroline, Salmen, Anke, Disanto, Giulio, Zecca, Chiara, D’Souza, Marcus, Orleth, Annette, Khalil, Michael, Buchmann, Arabella, Du Pasquier, Renaud, Yaldizli, Özgür, Derfuss, Tobias, Berger, Klaus, Hermesdorf, Marco, Wiendl, Heinz, Piehl, Fredrik, Battaglini, Marco, Fischer, Urs, Kappos, Ludwig, Gobbi, Claudio, Granziera, Cristina, Bridel, Claire, Leppert, David, Maleska Maceski, Aleksandra, Benkert, Pascal, Kuhle, Jens

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Association of Brain Atrophy With Disease Progression Independent of Relapse Activity in Patients With Relapsing Multiple Sclerosis von Cagol, Alessandro, Schaedelin, Sabine, Barakovic, Muhamed, Benkert, Pascal, Todea, Ramona-Alexandra, Rahmanzadeh, Reza, Galbusera, Riccardo, Lu, Po-Jui, Weigel, Matthias, Melie-Garcia, Lester, Ruberte, Esther, Siebenborn, Nina, Battaglini, Marco, Radue, Ernst-Wilhelm, Yaldizli, Özgür, Oechtering, Johanna, Sinnecker, Tim, Lorscheider, Johannes, Fischer-Barnicol, Bettina, Müller, Stefanie, Achtnichts, Lutz, Vehoff, Jochen, Disanto, Giulio, Findling, Oliver, Chan, Andrew, Salmen, Anke, Pot, Caroline, Bridel, Claire, Zecca, Chiara, Derfuss, Tobias, Lieb, Johanna M, Remonda, Luca, Wagner, Franca, Vargas, Maria I, Du Pasquier, Renaud, Lalive, Patrice H, Pravatà, Emanuele, Weber, Johannes, Cattin, Philippe C, Gobbi, Claudio, Leppert, David, Kappos, Ludwig, Kuhle, Jens, Granziera, Cristina

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Granulocyte Activation and Astrocyte Damage Markers in CSF Differentiate Acute NMOSD and MOGAD from MS (P9-14.004) von Leppert, David, Watanabe, Mitsuru, Schaedelin, Sabine, Piehl, Fredrik, Fink, Katharina, Furlan, Roberto, Gastaldi, Matteo, Benkert, Pascal, Maleska, Aleksandra, Willemse, Eline, Oechtering, Johanna, Orleth, Annette, Meier, Stephanie, Anthony, Daniel, Kuhle, Jens

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Serum neurofilament light chain reference database for individual application in paediatric care: a retrospective modelling and validation study von Abdelhak, Ahmed, Petermeier, Franziska, Benkert, Pascal, Schädelin, Sabine, Oechtering, Johanna, Maleska Maceski, Aleksandra, Kabesch, Michael, Geis, Tobias, Laub, Otto, Leipold, Georg, Gobbi, Claudio, Zecca, Chiara, Green, Ari, Tumani, Hayrettin, Willemse, Eline, Wiendl, Heinz, Granziera, Cristina, Kappos, Ludwig, Leppert, David, Waubant, Emmanuelle, Wellmann, Sven, Kuhle, Jens

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Intrathecal IgM production is a strong risk factor for early conversion to multiple sclerosis von Pfuhl, Catherina, Grittner, Ulrike, Gieß, René M, Scheel, Michael, Behrens, Janina R, Rasche, Ludwig, Pache, Florence C, Wenzel, Rüdiger, Brandt, Alexander U, Bellmann-Strobl, Judith, Paul, Friedemann, Ruprecht, Klemens, Oechtering, Johanna

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Intrathecal IgM Synthesis Is Associated with Spinal Cord Manifestation and Neuronal Injury in Early MS von Oechtering, Johanna, Lincke, Therese, Schaedelin, Sabine, Décard, Bernhard F., Maceski, Aleksandra, Orleth, Annette, Meier, Stephanie, Willemse, Eline, Buchmann, Arabella, Khalil, Michael, Derfuss, Tobias, Benkert, Pascal, Heijnen, Ingmar, Regeniter, Axel, Müller, Stefanie, Achtnichts, Lutz, Lalive, Patrice, Salmen, Anke, Pot, Caroline, Gobbi, Claudio, Kappos, Ludwig, Granziera, Cristina, Leppert, David, Schlaeger, Regina, Lieb, Johanna M., Kuhle, Jens

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Association of Spinal Cord Atrophy and Brain Paramagnetic Rim Lesions With Progression Independent of Relapse Activity in People With MS von Cagol, Alessandro, Benkert, Pascal, Melie-Garcia, Lester, Schaedelin, Sabine A, Leber, Selina, Tsagkas, Charidimos, Barakovic, Muhamed, Galbusera, Riccardo, Lu, Po-Jui, Weigel, Matthias, Ruberte, Esther, Radue, Ernst-Wilhelm, Yaldizli, Özgür, Oechtering, Johanna, Lorscheider, Johannes, D'Souza, Marcus, Fischer-Barnicol, Bettina, Müller, Stefanie, Achtnichts, Lutz, Vehoff, Jochen, Disanto, Giulio, Findling, Oliver, Chan, Andrew, Salmen, Anke, Pot, Caroline, Bridel, Claire, Zecca, Chiara, Derfuss, Tobias, Lieb, Johanna M, Remonda, Luca, Wagner, Franca, Vargas, Maria Isabel, Du Pasquier, Renaud A, Lalive, Patrice H, Pravatà, Emanuele, Weber, Johannes, Cattin, Philippe C, Absinta, Martina, Gobbi, Claudio, Leppert, David, Kappos, Ludwig, Kuhle, Jens, Granziera, Cristina

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Neurofilament Light Chain Elevation and Disability Progression in Multiple Sclerosis von Abdelhak, Ahmed, Benkert, Pascal, Schaedelin, Sabine, Boscardin, W. John, Cordano, Christian, Oechtering, Johanna, Ananth, Kirtana, Granziera, Cristina, Melie-Garcia, Lester, Montes, Shivany Condor, Beaudry-Richard, Alexandra, Achtnichts, Lutz, Oertel, Frederike C, Lalive, Patrice H, Leppert, David, Müller, Stefanie, Henry, Roland G, Pot, Caroline, Matthias, Amandine, Salmen, Anke, Oksenberg, Jorge R, Disanto, Giulio, Zecca, Chiara, D’Souza, Marcus, Du Pasquier, Renaud, Bridel, Claire, Gobbi, Claudio, Kappos, Ludwig, Hauser, Stephen L, Cree, Bruce A. C, Kuhle, Jens, Green, Ari J

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Granulocyte activation markers in cerebrospinal fluid differentiate acute neuromyelitis spectrum disorder from multiple sclerosis von Leppert, D, Watanabe, M, Schaedelin, S, Piehl, F, Furlan, R, Gastaldi, M, Lambert, J, Evertsson, B, Fink, K, Matsushita, T, Masaki, K, Isobe, N, Kira, JI, Benkert, P, Maceski, A, Willemse, E, Oechtering, J, Orleth, A, Meier, S, Kuhle, J

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Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5 von Callegari, Ilaria, Oechtering, Johanna, Schneider, Mika, Perriot, Sylvain, Mathias, Amandine, Voortman, Margarete M, Cagol, Alessandro, Lanner, Ulrike, Diebold, Martin, Holdermann, Sebastian, Kreiner, Victor, Becher, Burkhard, Granziera, Cristina, Junker, Andreas, Du Pasquier, Renaud, Khalil, Michael, Kuhle, Jens, Kappos, Ludwig, Sanderson, Nicholas S R, Derfuss, Tobias

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Cell-binding IgM in CSF is distinctive of multiple sclerosis and targets the iron transporter SCARA5 von Callegari, Ilaria, Oechtering, Johanna, Schneider, Mika, Perriot, Sylvain, Mathias, Amandine, Voortman, Margarete M, Cagol, Alessandro, Lanner, Ulrike, Diebold, Martin, Holdermann, Sebastian, Kreiner, Victor, Becher, Burkhard, Granziera, Cristina, Junker, Andreas, Du Pasquier, Renaud, Khalil, Michael, Kuhle, Jens, Kappos, Ludwig, Sanderson, Nicholas S R, Derfuss, Tobias

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