Abstract 3808: MYCN coordinately regulates the entire polyamine gene pathway to drive polyamine biosynthesis in neuroblastoma, with expression of every synthetic and catabolic poly... von Norris, Murray D., Gamble, Laura D., Murray, Jayne, Purgato, Stefania, Milazzo, Giorgio, Ashton, Lesley J., Oberthuer, Andrei, London, Wendy B., Hogarty, Mike D., Fischer, Mattias, Ziegler, David, Marshall, Glenn M., Perini, Giovanni, Haber, Michelle

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Rapid sample delivery for megahertz serial crystallography at X-ray FELs von Wiedorn, Max O, Awel, Salah, Morgan, Andrew J, Ayyer, Kartik, Gevorkov, Yaroslav, Fleckenstein, Holger, Roth, Nils, Adriano, Luigi, Bean, Richard, Beyerlein, Kenneth R, Chen, Joe, Coe, Jesse, Cruz-Mazo, Francisco, Ekeberg, Tomas, Graceffa, Rita, Heymann, Michael, Horke, Daniel A, Knoška, Juraj, Mariani, Valerio, Nazari, Reza, Oberthür, Dominik, Samanta, Amit K, Sierra, Raymond G, Stan, Claudiu A, Yefanov, Oleksandr, Rompotis, Dimitrios, Correa, Jonathan, Erk, Benjamin, Treusch, Rolf, Schulz, Joachim, Hogue, Brenda G, Gañán-Calvo, Alfonso M, Fromme, Petra, Küpper, Jochen, Rode, Andrei V, Bajt, Saša, Kirian, Richard A, Chapman, Henry N

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Femtosecond X‐ray diffraction from an aerosolized beam of protein nanocrystals von Awel, Salah, Kirian, Richard A., Wiedorn, Max O., Beyerlein, Kenneth R., Roth, Nils, Horke, Daniel A., Oberthür, Dominik, Knoska, Juraj, Mariani, Valerio, Morgan, Andrew, Adriano, Luigi, Tolstikova, Alexandra, Xavier, P. Lourdu, Yefanov, Oleksandr, Aquila, Andrew, Barty, Anton, Roy-Chowdhury, Shatabdi, Hunter, Mark S., James, Daniel, Robinson, Joseph S., Weierstall, Uwe, Rode, Andrei V., Bajt, Saša, Küpper, Jochen, Chapman, Henry N.

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Post‐sample aperture for low background diffraction experiments at X‐ray free‐electron lasers von Wiedorn, Max O., Awel, Salah, Morgan, Andrew J., Barthelmess, Miriam, Bean, Richard, Beyerlein, Kenneth R., Chavas, Leonard M. G., Eckerskorn, Niko, Fleckenstein, Holger, Heymann, Michael, Horke, Daniel A., Knoška, Juraj, Mariani, Valerio, Oberthür, Dominik, Roth, Nils, Yefanov, Oleksandr, Barty, Anton, Bajt, Saša, Küpper, Jochen, Rode, Andrei V., Kirian, Richard A., Chapman, Henry N.

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Abstract 1611: The FACT histone chaperone complex is highly expressed in aggressive drug refractory childhood cancers and the anti-FACT compound CBL0137 represents a highly promisi... von Haber, Michelle, Murray, Jayne, Gamble, Laura, Carnegie-Clark, Ashleigh, Webber, Hannah, Ruhle, Michelle, Henderson, Michelle J., Middlemass, Shiloh, Carter, Daniel, Tsoli, Maria, Ehteda, Anahid, Simon, Sandy, Oberthuer, Andre, Fischer, Matthias, Gurova, Katerina, Burkhart, Catherine, Purmal, Andrei, Lock, Richard B., Ziegler, David, Marshall, Glenn M., Gudkov, Andrei V., Norris, Murray D.

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Abstract PR09: MYCN and is a therapeutic target in neuroblastoma von Carter, Daniel R., Murray, Jayne, Cheung, Belamy B., Kalla, Heyam, Gamble, Laura, Tsang, Joanna, Sutton, Selina, Koach, Jessica, Syed, Sarah, Gifford, Andrew, Issaeva, Natalia, Biktasova, Asel, Atmadibrata, Bernard, Sun, Yuting, Sokolowski, Nicolas, Ling, Dora, Kim, Patrick Y., Webber, Hannah, Clark, Ashleigh, Ruhle, Michelle, Liu, Bing, Oberthuer, André, Fischer, Matthias, Byrne, Jennifer, Saletta, Federica, Purmal, Andrei, Ziegler, David, Liu, Tao, Gurova, Katerina V., Gudkov, Andrei V., Norris, Murray D., Haber, Michelle, Marshall, Glenn M.

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