Tumor-associated and microbial proteases compromise host IgG effector functions by a single cleavage proximal to the hinge von Brezski, Randall J, Vafa, Omid, Petrone, Diane, Tam, Susan H, Powers, Gordon, Ryan, Mary H, Luongo, Jennifer L, Oberholtzer, Allison, Knight, David M, Jordan, Robert E

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The in vitro resistance of IgG2 to proteolytic attack concurs with a comparative paucity of autoantibodies against peptide analogs of the IgG2 hinge von Brezski, Randall J., Oberholtzer, Allison, Strake, Brandy, Jordan, Robert E.

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A single proteolytic cleavage within the lower hinge of trastuzumab reduces immune effector function and in vivo efficacy von Fan, Xuejun, Brezski, Randall J, Fa, Ming, Deng, Hui, Oberholtzer, Allison, Gonzalez, Anneliese, Dubinsky, William P, Strohl, William R, Jordan, Robert E, Zhang, Ningyan, An, Zhiqiang

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A single proteolytic cleavage within the lower hinge of trastuzumab reduces immune effector function and in vivo efficacy von Fan, Xuejun, Brezski, Randall J, Fa, Ming, Deng, Hui, Oberholtzer, Allison, Gonzalez, Anneliese, Dubinsky, William P, Strohl, William R, Jordan, Robert E, Zhang, Ningyan, An, Zhiqiang

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Computational Immune Monitoring Reveals Abnormal Double-Negative T Cells Present across Human Tumor Types von Greenplate, Allison R, McClanahan, Daniel D, Oberholtzer, Brian K, Doxie, Deon B, Roe, Caroline E, Diggins, Kirsten E, Leelatian, Nalin, Rasmussen, Megan L, Kelley, Mark C, Gama, Vivian, Siska, Peter J, Rathmell, Jeffrey C, Ferrell, P Brent, Johnson, Douglas B, Irish, Jonathan M

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Ensemble computational analysis and systems immune monitoring reveal a double negative T cell subset enriched in melanoma tumors following dabrafenib and trametinib von Greenplate, Allison, Oberholtzer, Brian K., Doxie, Deon B., Roe, Caroline, Kelley, Mark C., Sosman, Jeffrey A, Johnson, Douglas B, Irish, Jonathan Michael

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