Noonan and LEOPARD syndrome Shp2 variants induce heart displacement defects in zebrafish von Bonetti, Monica, Paardekooper Overman, Jeroen, Tessadori, Federico, Noël, Emily, Bakkers, Jeroen, den Hertog, Jeroen

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Distinct and overlapping functions of ptpn11 genes in Zebrafish development von Bonetti, Monica, Rodriguez-Martinez, Virginia, Paardekooper Overman, Jeroen, Overvoorde, John, van Eekelen, Mark, Jopling, Chris, Hertog, Jeroen den

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SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development von Chiang, Ivy Kim-Ni, Fritzsche, Martin, Pichol-Thievend, Cathy, Neal, Alice, Holmes, Kelly, Lagendijk, Anne, Overman, Jeroen, D'Angelo, Donatella, Omini, Alice, Hermkens, Dorien, Lesieur, Emmanuelle, Liu, Ke, Ratnayaka, Indrika, Corada, Monica, Bou-Gharios, George, Carroll, Jason, Dejana, Elisabetta, Schulte-Merker, Stefan, Hogan, Benjamin, Beltrame, Monica, De Val, Sarah, Francois, Mathias

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Phosphoproteomics-mediated identification of Fer kinase as a target of mutant Shp2 in Noonan and LEOPARD syndrome von Paardekooper Overman, Jeroen, Preisinger, Christian, Prummel, Karin, Bonetti, Monica, Giansanti, Piero, Heck, Albert, den Hertog, Jeroen

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R-propranolol is a small molecule inhibitor of the SOX18 transcription factor in a rare vascular syndrome and hemangioma von Overman, Jeroen, Fontaine, Frank, Wylie-Sears, Jill, Moustaqil, Mehdi, Huang, Lan, Meurer, Marie, Chiang, Ivy Kim, Lesieur, Emmanuelle, Patel, Jatin, Zuegg, Johannes, Pasquier, Eddy, Sierecki, Emma, Gambin, Yann, Hamdan, Mohamed, Khosrotehrani, Kiarash, Andelfinger, Gregor, Bischoff, Joyce, Francois, Mathias

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Correction: Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice von Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril A B, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann, Francois, Mathias

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Pharmacological manipulation of transcription factor protein-protein interactions: opportunities and obstacles von Fontaine, Frank, Overman, Jeroen, François, Mathias

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Heterozygous germline mutations in A2ML1 are associated with a disorder clinically related to Noonan syndrome von Vissers, Lisenka E L M, Bonetti, Monica, Paardekooper Overman, Jeroen, Nillesen, Willy M, Frints, Suzanna G M, de Ligt, Joep, Zampino, Giuseppe, Justino, Ana, Machado, José C, Schepens, Marga, Brunner, Han G, Veltman, Joris A, Scheffer, Hans, Gros, Piet, Costa, José L, Tartaglia, Marco, van der Burgt, Ineke, Yntema, Helger G, den Hertog, Jeroen

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PZR Coordinates Shp2 Noonan and LEOPARD Syndrome Signaling in Zebrafish and Mice von Paardekooper Overman, Jeroen, Yi, Jae-Sung, Bonetti, Monica, Soulsby, Matthew, Preisinger, Christian, Stokes, Matthew P., Hui, Li, Silva, Jeffrey C., Overvoorde, John, Giansanti, Piero, Heck, Albert J. R., Kontaridis, Maria I., den Hertog, Jeroen, Bennett, Anton M.

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Pharmacological targeting of the transcription factor SOX18 delays breast cancer in mice von Overman, Jeroen, Fontaine, Frank, Moustaqil, Mehdi, Mittal, Deepak, Sierecki, Emma, Sacilotto, Natalia, Zuegg, Johannes, Robertson, Avril A B, Holmes, Kelly, Salim, Angela A, Mamidyala, Sreeman, Butler, Mark S, Robinson, Ashley S, Lesieur, Emmanuelle, Johnston, Wayne, Alexandrov, Kirill, Black, Brian L, Hogan, Benjamin M, De Val, Sarah, Capon, Robert J, Carroll, Jason S, Bailey, Timothy L, Koopman, Peter, Jauch, Ralf, Cooper, Matthew A, Gambin, Yann, Francois, Mathias

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Zebrafish as a model to study PTPs during development von Paardekooper Overman, Jeroen, den Hertog, Jeroen

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Correction: SoxF factors induce Notch1 expression via direct transcriptional regulation during early arterial development. Development doi: 10.1242/dev.146241 von Chiang, Ivy Kim-Ni, Fritzsche, Martin, Pichol-Thievend, Cathy, Neal, Alice, Holmes, Kelly, Lagendijk, Anne, Overman, Jeroen, D'Angelo, Donatella, Omini, Alice, Hermkens, Dorien, Lesieur, Emmanuelle, Fossat, Nicolas, Radziewic, Tania, Liu, Ke, Ratnayaka, Indrika, Corada, Monica, Bou-Gharios, George, Tam, Patrick P L, Carroll, Jason, Dejana, Elisabetta, Schulte-Merker, Stefan, Hogan, Benjamin M, Beltrame, Monica, De Val, Sarah, Francois, Mathias

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Abstract 3232: In vitro cell based cytotoxicity and T cell activation assays to assess safety and efficacy of engineered T cell therapies von Holt, Sanne, Vermond, Sophie, Hazenoot, Monique Hazenoot, Overman, Jeroen, Aarbiou, Jamil Aarbiou, DeGroot, Jeroen DeGroot

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Exploring the Dispersion and Electrostatic Components in Arene–Arene Interactions between Ligands and G4 DNA to Develop G4-Ligands von Andreasson, Måns, Donzel, Maxime, Abrahamsson, Alva, Berner, Andreas, Doimo, Mara, Quiroga, Anna, Eriksson, Anna, Chao, Yu-Kai, Overman, Jeroen, Pemberton, Nils, Wanrooij, Sjoerd, Chorell, Erik

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Small-Molecule Inhibitors of the SOX18 Transcription Factor von Fontaine, Frank, Overman, Jeroen, Moustaqil, Mehdi, Mamidyala, Sreeman, Salim, Angela, Narasimhan, Kamesh, Prokoph, Nina, Robertson, Avril A.B., Lua, Linda, Alexandrov, Kirill, Koopman, Peter, Capon, Robert J., Sierecki, Emma, Gambin, Yann, Jauch, Ralf, Cooper, Matthew A., Zuegg, Johannes, Francois, Mathias

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Homodimerization regulates an endothelial specific signature of the SOX18 transcription factor von Moustaqil, Mehdi, Fontaine, Frank, Overman, Jeroen, McCann, Alex, Bailey, Timothy L, Rudolffi Soto, Paulina, Bhumkar, Akshay, Giles, Nichole, Hunter, Dominic J B, Gambin, Yann, Francois, Mathias, Sierecki, Emma

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Establishing a transcription factors protein network for lymphangiogenesis: identification of binding domains, impact of pathological mutations and perturbations by small molecules von Moustaqil, Mehdi, Overman, Jeroen, Fontaine, Franck, Bailey, Timothey, Francois, Mathias, Gambin, Yann, Sierecki, Emma

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Tracking Dynamics of Vascular Development in Time and Space using Sox18 Dimer split‐Fluorescent Protein Biosensors von Giles, Nichole, McCann, Alex, Moustaqil, Mehdi, Overman, Jeroen, Fontaine, Franck, Francois, Mathias, Sierecki, Emma, Gambin, Yann

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SOX18 transcription factor interactome: Protein‐Protein interaction a new road for anti‐cancer drug discovery von Moustaqil, Mehdi Denis, Fontaine, Frank, Overman, Jeroen, Giles, Nichole Denis, Bhumkar, Akshay Denis, O'Caroll, Ailis Denis, Francois, Mathias, Gambin, Yann Denis, Sierecki, Emma Denis

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Understanding of Molecular Substructures that Contribute to hERG K+ Channel Blockade: Synthesis and Biological Evaluation of E-4031 Analogues von Vilums, Maris, Overman, Jeroen, Klaasse, Elisabeth, Scheel, Olaf, Brussee, Johannes, IJzerman, Adriaan P.

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