Chemically Induced Degradation of Sirtuin 2 (Sirt2) by a Proteolysis Targeting Chimera (PROTAC) Based on Sirtuin Rearranging Ligands (SirReals) von Schiedel, Matthias, Herp, Daniel, Hammelmann, Sören, Swyter, Sören, Lehotzky, Attila, Robaa, Dina, Oláh, Judit, Ovádi, Judit, Sippl, Wolfgang, Jung, Manfred

Volltext

Aminothiazoles as Potent and Selective Sirt2 Inhibitors: A Structure–Activity Relationship Study von Schiedel, Matthias, Rumpf, Tobias, Karaman, Berin, Lehotzky, Attila, Oláh, Judit, Gerhardt, Stefan, Ovádi, Judit, Sippl, Wolfgang, Einsle, Oliver, Jung, Manfred

Volltext

Selective Sirt2 inhibition by ligand-induced rearrangement of the active site von Rumpf, Tobias, Schiedel, Matthias, Karaman, Berin, Roessler, Claudia, North, Brian J., Lehotzky, Attila, Oláh, Judit, Ladwein, Kathrin I., Schmidtkunz, Karin, Gajer, Markus, Pannek, Martin, Steegborn, Clemens, Sinclair, David A., Gerhardt, Stefan, Ovádi, Judit, Schutkowski, Mike, Sippl, Wolfgang, Einsle, Oliver, Jung, Manfred

Volltext

Challenges in Discovering Drugs That Target the Protein-Protein Interactions of Disordered Proteins von Oláh, Judit, Szénási, Tibor, Lehotzky, Attila, Norris, Victor, Ovádi, Judit

Volltext

Pharmacological targeting of α‐synuclein and TPPP/p25 in Parkinson's disease: challenges and opportunities in a Nutshell von Oláh, Judit, Ovádi, Judit

Volltext

Triosephosphate isomerase deficiency: New insights into an enigmatic disease von Orosz, Ferenc, Oláh, Judit, Ovádi, Judit

Volltext

Role of Multifunctional Cytoskeletal Filaments in Coronaviridae Infections: Therapeutic Opportunities for COVID-19 in a Nutshell von Norris, Victor, Ovádi, Judit

Volltext

Perspective Strategies for Interventions in Parkinsonism: Remedying the Neglected Role of TPPP von Oláh, Judit, Norris, Vic, Lehotzky, Attila, Ovádi, Judit

Volltext

Structure-Based Development of an Affinity Probe for Sirtuin 2 von Schiedel, Matthias, Rumpf, Tobias, Karaman, Berin, Lehotzky, Attila, Gerhardt, Stefan, Ovádi, Judit, Sippl, Wolfgang, Einsle, Oliver, Jung, Manfred

Volltext

New chemical tools for probing activity and inhibition of the NAD+-dependent lysine deacylase sirtuin 2 von Swyter, Sören, Schiedel, Matthias, Monaldi, Daria, Szunyogh, Sándor, Lehotzky, Attila, Rumpf, Tobias, Ovádi, Judit, Sippl, Wolfgang, Jung, Manfred

Volltext

Nuclear translocation of the tumor marker pyruvate kinase M2 induces programmed cell death von STETAK, Attila, VERESS, Réka, OVADI, Judit, CSERMELY, Péter, KERI, Gyorgy, ULLRICH, Axel

Volltext

Moonlighting proteins in neurological disorders von Ovadi, Judit

Volltext

Proteins without 3D structure: definition, detection and beyond von OROSZ, Ferenc, OVADI, Judit

Volltext

Modulatory Role of TPPP3 in Microtubule Organization and Its Impact on Alpha-Synuclein Pathology von Oláh, Judit, Lehotzky, Attila, Szénási, Tibor, Berki, Tímea, Ovádi, Judit

Volltext

Tubulin polymerization-promoting protein (TPPP/p25) is critical for oligodendrocyte differentiation von Lehotzky, Attila, Lau, Pierre, Tőkési, Natália, Muja, Naser, Hudson, Lynn D., Ovádi, Judit

Volltext

HaloTag‐Targeted Sirtuin‐Rearranging Ligand (SirReal) for the Development of Proteolysis‐Targeting Chimeras (PROTACs) against the Lysine Deacetylase Sirtuin 2 (Sirt2) von Schiedel, Matthias, Lehotzky, Attila, Szunyogh, Sandor, Oláh, Judit, Hammelmann, Sören, Wössner, Nathalie, Robaa, Dina, Einsle, Oliver, Sippl, Wolfgang, Ovádi, Judit, Jung, Manfred

Volltext

TPPP/p25 Promotes Tubulin Acetylation by Inhibiting Histone Deacetylase 6 von Tőkési, Natália, Lehotzky, Attila, Horváth, István, Szabó, Bálint, Oláh, Judit, Lau, Pierre, Ovádi, Judit

Volltext

The Sherpa hypothesis: Phenotype-Preserving Disordered Proteins stabilize the phenotypes of neurons and oligodendrocytes von Norris, Vic, Oláh, Judit, Krylov, Sergey N., Uversky, Vladimir N., Ovádi, Judit

Volltext

Microtubule-Associated Proteins with Regulatory Functions by Day and Pathological Potency at Night von Oláh, Judit, Lehotzky, Attila, Szunyogh, Sándor, Szénási, Tibor, Orosz, Ferenc, Ovádi, Judit

Volltext

unstructured protein with destructive potential: TPPP/p25 in neurodegeneration von Ovádi, Judit, Orosz, Ferenc

Volltext