Clinical Pharmacokinetic Studies of Enzalutamide von Gibbons, Jacqueline A., Ouatas, Taoufik, Krauwinkel, Walter, Ohtsu, Yoshiaki, van der Walt, Jan-Stefan, Beddo, Vanessa, de Vries, Michiel, Mordenti, Joyce

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Enzalutamide monotherapy in hormone-naive prostate cancer: primary analysis of an open-label, single-arm, phase 2 study von Tombal, Bertrand, Prof, Borre, Michael, Prof, Rathenborg, Per, MD, Werbrouck, Patrick, MD, Van Poppel, Hendrik, Prof, Heidenreich, Axel, Prof, Iversen, Peter, Prof, Braeckman, Johan, Prof, Heracek, Jiri, MD, Baskin-Bey, Edwina, MD, Ouatas, Taoufik, PhD, Perabo, Frank, MD, Phung, De, BSc, Hirmand, Mohammad, MD, Smith, Matthew R, Prof

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Effect of cyclosporine coadministration on the pharmacokinetics of eltrombopag in healthy volunteers von Aslanis, Vassilios, Zhang, Jianping, Lomeli, Barbara, Grosch, Kai, Ouatas, Taoufik

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Endocan Expression and Relationship with Survival in Human Non–Small Cell Lung Cancer von GRIGORIU, Bogdan Dragos, DEPONTIEU, Florence, SCHERPEREEL, Arnaud, GOURCEROL, Delphine, DEVOS, Patrick, OUATAS, Taoufik, LAFITTE, Jean-Jacques, COPIN, Marie-Christine, TONNEL, Andre-Bernard, LASSALLE, Philippe

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Nm23-H1 Metastasis Suppressor Phosphorylation of Kinase Suppressor of Ras via a Histidine Protein Kinase Pathway von Hartsough, Melanie T, Morrison, Deborah K, Salerno, Massimiliano, Palmieri, Diane, Ouatas, Taoufik, Mair, Michael, Patrick, Jilma, Steeg, Patricia S

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Medroxyprogesterone Acetate Elevation of Nm23-H1 Metastasis Suppressor Expression in Hormone Receptor–Negative Breast Cancer von Palmieri, Diane, Halverson, Douglas O., Ouatas, Taoufik, Horak, Christine E., Salerno, Massimiliano, Johnson, Jennifer, Figg, W. Douglas, Hollingshead, Melinda, Hursting, Stephen, Berrigan, David, Steinberg, Seth M., Merino, Maria J., Steeg, Patricia S.

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Evaluation of drug–drug interactions between midostaurin and strong CYP3A4 inhibitors in patients with FLT-3-mutated acute myeloid leukemia (AML) von Sechaud, Romain, Sinclair, Karen, Grosch, Kai, Ouatas, Taoufik, Pathak, Dhrubajyoti

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Pharmacokinetic Drug Interaction Studies with Enzalutamide von Gibbons, Jacqueline A., de Vries, Michiel, Krauwinkel, Walter, Ohtsu, Yoshiaki, Noukens, Jan, van der Walt, Jan-Stefan, Mol, Roelof, Mordenti, Joyce, Ouatas, Taoufik

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Modeling and Simulation Support Eltrombopag Dosing in Pediatric Patients With Immune Thrombocytopenia von Wire, Mary B., Li, Xiaobin, Zhang, Jianping, Sallas, William, Aslanis, Vassilios, Ouatas, Taoufik

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Multiple administrations of fluconazole increase plasma exposure to ruxolitinib in healthy adult subjects von Aslanis, Vassilios, Umehara, Kenichi, Huth, Felix, Ouatas, Taoufik, Bharathy, Savita, Butler, Andrew Avigdor, Zhou, Wen, Gadbaw, Brian

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Concomitant Use of Midostaurin with Strong CYP3A4 Inhibitors: An Analysis from the Ratify Trial von Ouatas, Taoufik, Duval, Vincent, Sinclair, Karen, Berkowitz, Noah

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Simultaneous Physiologically Based Pharmacokinetic (PBPK) Modeling of Parent and Active Metabolites to Investigate Complex CYP3A4 Drug-Drug Interaction Potential: A Case Example of... von Gu, Helen, Dutreix, Catherine, Rebello, Sam, Ouatas, Taoufik, Wang, Lai, Chun, Dung Yu, Einolf, Heidi J., He, Handan

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Long-term Efficacy and Safety of Enzalutamide Monotherapy in Hormone-naïve Prostate Cancer: 1- and 2-Year Open-label Follow-up Results von Tombal, Bertrand, Borre, Michael, Rathenborg, Per, Werbrouck, Patrick, Van Poppel, Hendrik, Heidenreich, Axel, Iversen, Peter, Braeckman, Johan, Heracek, Jiri, Baskin-Bey, Edwina, Ouatas, Taoufik, Perabo, Frank, Phung, De, Baron, Benoit, Hirmand, Mohammad, Smith, Matthew R

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In vitro and in vivo characterisation of ASP9521: a novel, selective, orally bioavailable inhibitor of 17β-hydroxysteroid dehydrogenase type 5 (17βHSD5; AKR1C3) von Kikuchi, Aya, Furutani, Takashi, Azami, Hidenori, Watanabe, Kazushi, Niimi, Tatsuya, Kamiyama, Yoshiteru, Kuromitsu, Sadao, Baskin-Bey, Edwina, Heeringa, Marten, Ouatas, Taoufik, Enjo, Kentaro

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Phase Ib Study of Enzalutamide in Combination with Docetaxel in Men with Metastatic Castration-Resistant Prostate Cancer von Morris, Michael J, Rathkopf, Dana E, Novotny, William, Gibbons, Jacqueline A, Peterson, Amy C, Khondker, Zakaria, Ouatas, Taoufik, Scher, Howard I, Fleming, Mark T

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Safety, tolerability and anti-tumour activity of the androgen biosynthesis inhibitor ASP9521 in patients with metastatic castration-resistant prostate cancer: multi-centre phase I/... von Loriot, Yohann, Fizazi, Karim, Jones, Robert J., Van den Brande, Jan, Molife, Rhoda L., Omlin, Aurelius, James, Nicholas D., Baskin-Bey, Edwina, Heeringa, Marten, Baron, Benoit, Holtkamp, Gertjan M., Ouatas, Taoufik, De Bono, Johann S.

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Enzalutamide (ENZA) in combination with abiraterone acetate (AA) in bone metastatic castration resistant prostate cancer (mCRPC) von Efstathiou, Eleni, Titus, Mark Anton, Wen, Sijin, SanMiguel, Aileen, Hoang, Anh, De Haas-Amatsaleh, Angela, Perabo, Frank, Phung, De, Troncoso, Patricia, Ouatas, Taoufik, Logothetis, Christopher

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TERRAIN: A randomized, double-blind, phase II study comparing MDV3100 with bicalutamide (Bic) in men with metastatic castrate-resistant prostate cancer (CRPC) von Baskin-Bey, Edwina S., Shore, Neal D., Barber, Kenya, Ouatas, Taoufik, Heidenreich, Axel

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Dexamethasone and medroxyprogesterone acetate elevate Nm23-H1 metastasis suppressor gene expression in metastatic human breast carcinoma cells: New uses for old compounds von OUATAS, Taoufik, HALVERSON, Douglas, STEED, Patricia S

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Enzalutamide monotherapy: One-year extended follow-up of a phase 2 study in hormone-naive prostate cancer patients von Tombal, Bertrand F., Borre, Michael, Rathenborg, Per, Werbrouck, Patrick, Van Poppel, Hendrik, Heidenreich, Axel, Iversen, Peter, Braeckman, Johan, Heracek, Jiri, Baskin-Bey, Edwina, Ouatas, Taoufik, Perabo, Frank, Phung, De, Hirmand, Mohammad, Smith, Matthew Raymond

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