Small-Molecule Stabilization of Protein-Protein Interactions: An Underestimated Concept in Drug Discovery? von Thiel, Philipp, Kaiser, Markus, Ottmann, Christian

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Modulators of Protein–Protein Interactions von Milroy, Lech-Gustav, Grossmann, Tom N, Hennig, Sven, Brunsveld, Luc, Ottmann, Christian

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14-3-3: A Case Study in PPI Modulation von Ballone, Alice, Centorrino, Federica, Ottmann, Christian

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Modulators of 14-3‑3 Protein–Protein Interactions von Stevers, Loes M, Sijbesma, Eline, Botta, Maurizio, MacKintosh, Carol, Obsil, Tomas, Landrieu, Isabelle, Cau, Ylenia, Wilson, Andrew J, Karawajczyk, Anna, Eickhoff, Jan, Davis, Jeremy, Hann, Michael, O’Mahony, Gavin, Doveston, Richard G, Brunsveld, Luc, Ottmann, Christian

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Ultra-large chemical libraries for the discovery of high-affinity peptide binders von Quartararo, Anthony J., Gates, Zachary P., Somsen, Bente A., Hartrampf, Nina, Ye, Xiyun, Shimada, Arisa, Kajihara, Yasuhiro, Ottmann, Christian, Pentelute, Bradley L.

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Intermolecular channels direct crystal orientation in mineralized collagen von Xu, YiFei, Nudelman, Fabio, Eren, E. Deniz, Wirix, Maarten J. M., Cantaert, Bram, Nijhuis, Wouter H., Hermida-Merino, Daniel, Portale, Giuseppe, Bomans, Paul H. H., Ottmann, Christian, Friedrich, Heiner, Bras, Wim, Akiva, Anat, Orgel, Joseph P. R. O., Meldrum, Fiona C., Sommerdijk, Nico

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Stabilization of protein–protein interactions by small molecules von Giordanetto, Fabrizio, Schäfer, Anja, Ottmann, Christian

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A Binary Bivalent Supramolecular Assembly Platform Based on Cucurbit[8]uril and Dimeric Adapter Protein 14‐3‐3 von de Vink, Pim J., Briels, Jeroen M., Schrader, Thomas, Milroy, Lech‐Gustav, Brunsveld, Luc, Ottmann, Christian

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Structure-based evolution of a promiscuous inhibitor to a selective stabilizer of protein–protein interactions von Sijbesma, Eline, Visser, Emira, Plitzko, Kathrin, Thiel, Philipp, Milroy, Lech-Gustav, Kaiser, Markus, Brunsveld, Luc, Ottmann, Christian

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The Molecular Tweezer CLR01 Stabilizes a Disordered Protein–Protein Interface von Bier, David, Mittal, Sumit, Bravo-Rodriguez, Kenny, Sowislok, Andrea, Guillory, Xavier, Briels, Jeroen, Heid, Christian, Bartel, Maria, Wettig, Burkhard, Brunsveld, Luc, Sanchez-Garcia, Elsa, Schrader, Thomas, Ottmann, Christian

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A simple method for developing lysine targeted covalent protein reagents von Gabizon, Ronen, Tivon, Barr, Reddi, Rambabu N., van den Oetelaar, Maxime C. M., Amartely, Hadar, Cossar, Peter J., Ottmann, Christian, London, Nir

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Stabilization of Protein–Protein Interactions in chemical biology and drug discovery von Bier, David, Thiel, Philipp, Briels, Jeroen, Ottmann, Christian

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Stabilization of Protein–Protein Interactions between CaMKK2 and 14–3–3 by Fusicoccins von Lentini Santo, Domenico, Petrvalska, Olivia, Obsilova, Veronika, Ottmann, Christian, Obsil, Tomas

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TEAD–YAP Interaction Inhibitors and MDM2 Binders from DNA‐Encoded Indole‐Focused Ugi Peptidomimetics von Kunig, Verena B. K., Potowski, Marco, Akbarzadeh, Mohammad, Klika Škopić, Mateja, Santos Smith, Denise, Arendt, Lukas, Dormuth, Ina, Adihou, Hélène, Andlovic, Blaž, Karatas, Hacer, Shaabani, Shabnam, Zarganes‐Tzitzikas, Tryfon, Neochoritis, Constantinos G., Zhang, Ran, Groves, Matthew, Guéret, Stéphanie M., Ottmann, Christian, Rahnenführer, Jörg, Fried, Roland, Dömling, Alexander, Brunschweiger, Andreas

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Structural view of a fungal toxin acting on a 14-3-3 regulatory complex von Würtele, Martin, Jelich-Ottmann, Christian, Wittinghofer, Alfred, Oecking, Claudia

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Macrocycle-stabilization of its interaction with 14-3-3 increases plasma membrane localization and activity of CFTR von Stevers, Loes M., Wolter, Madita, Carlile, Graeme W., Macdonald, Dwight, Richard, Luc, Gielkens, Frank, Hanrahan, John W., Thomas, David Y., Chakka, Sai Kumar, Peterson, Mark L., Thomas, Helmut, Brunsveld, Luc, Ottmann, Christian

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Stabilization and Inhibition of Protein–Protein Interactions: The 14-3‑3 Case Study von Milroy, Lech-Gustav, Brunsveld, Luc, Ottmann, Christian

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Characterization and small-molecule stabilization of the multisite tandem binding between 14-3-3 and the R domain of CFTR von Stevers, Loes M., Lam, Chan V., Leysen, Seppe F. R., Meijer, Femke A., van Scheppingen, Daphne S., de Vries, Rens M. J. M., Carlile, Graeme W., Milroy, Lech G., Thomas, David Y., Brunsveld, Luc, Ottmann, Christian

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Impaired Binding of 14-3-3 to C-RAF in Noonan Syndrome Suggests New Approaches in Diseases with Increased Ras Signaling von Molzan, Manuela, Schumacher, Benjamin, Ottmann, Corinna, Baljuls, Angela, Polzien, Lisa, Weyand, Michael, Thiel, Philipp, Rose, Rolf, Rose, Micheline, Kuhenne, Philipp, Kaiser, Markus, Rapp, Ulf R., Kuhlmann, Jürgen, Ottmann, Christian

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Activation of NF-κB signalling by fusicoccin-induced dimerization von Skwarczynska, Malgorzata, Molzan, Manuela, Ottmann, Christian

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