Doxorubicin overproduction in Streptomyces peucetius: cloning and characterization of the dnrU ketoreductase and dnrV genes and the doxA cytochrome P-450 hydroxylase gene von Lomovskaya, N, Otten, S L, Doi-Katayama, Y, Fonstein, L, Liu, X C, Takatsu, T, Inventi-Solari, A, Filippini, S, Torti, F, Colombo, A L, Hutchinson, C R

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The dnrO gene encodes a DNA-binding protein that regulates daunorubicin production in Streptomyces peucetius by controlling expression of the dnrN pseudo response regulator gene von Otten, Sharee L, Olano, Carlos, Hutchinson, C. Richard

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A perspective on drug discovery and development through the genetic engineering of antibiotic-producing microorganisms von Hutchinson, C. Richard, Borell, Christopher W, Otten, Sharee L, Stutzman-Engwall, Kim J, Wang, Yi Guang

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FREQUENT LOSS AND RESTORATION OF ANTIBIOTIC PRODUCTION BY STREPTOMYCES LASALIENSIS von KINASHI, HARUYASU, OTTEN, SHAREE L., DUNCANN, JANICE S., HUTCHINSON, C. RICHARD

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Structure–function analysis of tRNA Gln in an Escherichia coli knockout strain von MCCLAIN, WILLIAM H., GABRIEL, KAY, LEE, DENNIS, OTTEN, SHAREE

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Structure–function analysis of tRNAGln in an Escherichia coli knockout strain von MCCLAIN, WILLIAM H., GABRIEL, KAY, LEE, DENNIS, OTTEN, SHAREE

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Microbial Transformations of Natural Antitumor Agents. 17. Conversions of Lapachol by Cunninghamella echinulata von Otten, Sharee L, Rosazza, John P

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Recognition of acceptor-stem structure of tRNA(Asp) by Escherichia coli aspartyl-tRNA synthetase von Choi, Hyunsic, Gabriel, Kay, Schneider, Jay, Otten, Sharee, McClain, William H

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Recognition of acceptor-stem structure of tRNAAsp by Escherichia coli aspartyl-tRNA synthetase von CHOI, HYUNSIC, GABRIEL, KAY, SCHNEIDER, JAY, OTTEN, SHAREE, McCLAIN, WILLIAM H.

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Recognition of acceptor-stem structure of tRNA Asp by Escherichia coli aspartyl-tRNA synthetase von CHOI, HYUNSIC, GABRIEL, KAY, SCHNEIDER, JAY, OTTEN, SHAREE, McCLAIN, WILLIAM H.

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Structure-function analysis of tRNA(Gln) in an Escherichia coli knockout strain von McClain, William H, Gabriel, Kay, Lee, Dennis, Otten, Sharee

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Genetic Perturbations of RNA Reveal Structure-based Recognition in Protein–RNA Interaction von Choi, Hyunsic, Otten, Sharee, Schneider, Jay, McClain, William H.

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Regulation of secondary metabolism in Streptomyces spp. and overproduction of daunorubicin in Streptomyces peucetius von STUTZMAN-ENGWALL, K. J, OTTEN, S. L, RICHARD HUTCHINSON, C

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Cloning and characterization of the Streptomyces peucetius dnmZUV genes encoding three enzymes required for biosynthesis of the daunorubicin precursor thymidine diphospho-L-daunosa... von Otten, S L, Gallo, M A, Madduri, K, Liu, X, Hutchinson, C R

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Regulation of daunorubicin production in Streptomyces peucetius by the dnrR2 locus von Otten, S L, Ferguson, J, Hutchinson, C R

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Cloning and characterization of the Streptomyces peucetius dnrQS genes encoding a daunosamine biosythesis enzyme and a glycosyl transferase involved in daunorubicin biosythesis von Otten, Sharee L, Liu, Xiaochun, Ferguson, Jane, Hutchinson, C Richard

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Cloning and characterization of the Streptomyces peucetis dnmZUV genes encoding three enzumes required for biosynthesis of the daunorubicin precursor thymidine diphospho-L-daunosam... von Otten, Sharee I, Gallo, Mark A, Madduri, Krishnamurthy, Liu, Xiaochun, Hutchinson, C Richard

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Genetic control of polyketide biosynthesis in the genusStreptomyces von Hutchinson, C. Richard, Decker, Heinrich, Madduri, Krishnamurthy, Otten, Sharee L., Tang, Li

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Genetic control of polyketide biosynthesis in the genus Streptomyces von Hutchinson, C R, Decker, H, Madduri, K, Otten, S L, Tang, L

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Drug discovery and development through the genetic engineering of antibiotic-producing microorganisms von Hutchinson, C R, Borell, C W, Otten, S L, Stutzman-Engwall, K J, Wang, Y G

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