Mitochondrial DNA as an inflammatory mediator in cardiovascular diseases von Nakayama, Hiroyuki, Otsu, Kinya

Volltext

Fibroblast-Specific Genetic Manipulation of p38 Mitogen-Activated Protein Kinase In Vivo Reveals Its Central Regulatory Role in Fibrosis von Molkentin, Jeffery D, Bugg, Darrian, Ghearing, Natasha, Dorn, Lisa E, Kim, Peter, Sargent, Michelle A, Gunaje, Jagadambika, Otsu, Kinya, Davis, Jennifer

Volltext

Iron derived from autophagy-mediated ferritin degradation induces cardiomyocyte death and heart failure in mice von Ito, Jumpei, Omiya, Shigemiki, Rusu, Mara-Camelia, Ueda, Hiromichi, Murakawa, Tomokazu, Tanada, Yohei, Abe, Hajime, Nakahara, Kazuki, Asahi, Michio, Taneike, Manabu, Nishida, Kazuhiko, Shah, Ajay M, Otsu, Kinya

Volltext

A Mammalian Mitophagy Receptor, Bcl2-L-13, Recruits the ULK1 Complex to Induce Mitophagy von Murakawa, Tomokazu, Okamoto, Koji, Omiya, Shigemiki, Taneike, Manabu, Yamaguchi, Osamu, Otsu, Kinya

Volltext

Crosstalk Between Autophagy and Apoptosis in Heart Disease von Nishida, Kazuhiko, Yamaguchi, Osamu, Otsu, Kinya

Volltext

BCL2L13 is a mammalian homolog of the yeast mitophagy receptor Atg32 von Otsu, Kinya, Murakawa, Tomokazu, Yamaguchi, Osamu

Volltext

Discovery of Atg5/Atg7-independent alternative macroautophagy von Nishida, Yuya, Arakawa, Satoko, Fujitani, Kenji, Yamaguchi, Hirofumi, Mizuta, Takeshi, Kanaseki, Toku, Komatsu, Masaaki, Otsu, Kinya, Tsujimoto, Yoshihide, Shimizu, Shigeomi

Volltext

Sterile Inflammation and Degradation Systems in Heart Failure von Nishida, Kazuhiko, Otsu, Kinya

Volltext

MicroRNA-451 Exacerbates Lipotoxicity in Cardiac Myocytes and High-Fat Diet-Induced Cardiac Hypertrophy in Mice Through Suppression of the LKB1/AMPK Pathway von Kuwabara, Yasuhide, Horie, Takahiro, Baba, Osamu, Watanabe, Shin, Nishiga, Masataka, Usami, Shunsuke, Izuhara, Masayasu, Nakao, Tetsushi, Nishino, Tomohiro, Otsu, Kinya, Kita, Toru, Kimura, Takeshi, Ono, Koh

Volltext

Involvement of p38 in Age-Related Decline in Adult Neurogenesis via Modulation of Wnt Signaling von Kase, Yoshitaka, Otsu, Kinya, Shimazaki, Takuya, Okano, Hideyuki

Volltext

The role of autophagic degradation in the heart von Nishida, Kazuhiko, Taneike, Manabu, Otsu, Kinya

Volltext

Pathological neoangiogenesis depends on oxidative stress regulation by ATM von Okuno, Yuji, Nakamura-Ishizu, Ayako, Otsu, Kinya, Suda, Toshio, Kubota, Yoshiaki

Volltext

Macrophage hypoxia signaling regulates cardiac fibrosis via Oncostatin M von Abe, Hajime, Takeda, Norihiko, Isagawa, Takayuki, Semba, Hiroaki, Nishimura, Satoshi, Morioka, Masaki Suimye, Nakagama, Yu, Sato, Tatsuyuki, Soma, Katsura, Koyama, Katsuhiro, Wake, Masaki, Katoh, Manami, Asagiri, Masataka, Neugent, Michael L., Kim, Jung-whan, Stockmann, Christian, Yonezawa, Tomo, Inuzuka, Ryo, Hirota, Yasushi, Maemura, Koji, Yamashita, Takeshi, Otsu, Kinya, Manabe, Ichiro, Nagai, Ryozo, Komuro, Issei

Volltext

Translation of hemodynamic stress to sterile inflammation in the heart von Nakayama, Hiroyuki, Otsu, Kinya

Volltext

Inflammation and metabolic cardiomyopathy von Nishida, Kazuhiko, Otsu, Kinya

Volltext

The role of autophagy in cardiomyocytes in the basal state and in response to hemodynamic stress von Nakai, Atsuko, Yamaguchi, Osamu, Takeda, Toshihiro, Higuchi, Yoshiharu, Hikoso, Shungo, Taniike, Masayuki, Omiya, Shigemiki, Mizote, Isamu, Matsumura, Yasushi, Asahi, Michio, Nishida, Kazuhiko, Hori, Masatsugu, Mizushima, Noboru, Otsu, Kinya

Volltext

Cardiac fibroblasts are essential for the adaptive response of the murine heart to pressure overload von Takeda, Norifumi, Manabe, Ichiro, Uchino, Yuichi, Eguchi, Kosei, Matsumoto, Sahohime, Nishimura, Satoshi, Shindo, Takayuki, Sano, Motoaki, Otsu, Kinya, Snider, Paige, Conway, Simon J, Nagai, Ryozo

Volltext

Ablation of Toll-like receptor 9 attenuates myocardial ischemia/reperfusion injury in mice von Kitazume-Taneike, Rika, Taneike, Manabu, Omiya, Shigemiki, Misaka, Tomofumi, Nishida, Kazuhiko, Yamaguchi, Osamu, Akira, Shizuo, Shattock, Michael J., Sakata, Yasushi, Otsu, Kinya

Volltext

Perilipin 5, a Lipid Droplet-binding Protein, Protects Heart from Oxidative Burden by Sequestering Fatty Acid from Excessive Oxidation von Kuramoto, Kenta, Okamura, Tomoo, Yamaguchi, Tomohiro, Nakamura, Tomoe Y., Wakabayashi, Shigeo, Morinaga, Hidetaka, Nomura, Masatoshi, Yanase, Toshihiko, Otsu, Kinya, Usuda, Nobuteru, Matsumura, Shigenobu, Inoue, Kazuo, Fushiki, Tohru, Kojima, Yumiko, Hashimoto, Takeshi, Sakai, Fumie, Hirose, Fumiko, Osumi, Takashi

Volltext

Inhibition of autophagy in the heart induces age-related cardiomyopathy von Taneike, Manabu, Yamaguchi, Osamu, Nakai, Atsuko, Hikoso, Shungo, Takeda, Toshihiro, Mizote, Isamu, Oka, Takafumi, Tamai, Takahito, Oyabu, Jota, Murakawa, Tomokazu, Nishida, Kazuhiko, Shimizu, Takahiko, Hori, Masatsugu, Komuro, Issei, Takuji Shirasawa, Takuji Shirasawa, Mizushima, Noboru, Otsu, Kinya

Volltext