Fatty acid synthesis configures the plasma membrane for inflammation in diabetes von Wei, Xiaochao, Song, Haowei, Yin, Li, Rizzo, Michael G., Sidhu, Rohini, Covey, Douglas F., Ory, Daniel S., Semenkovich, Clay F.

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Lysosomal cholesterol activates mTORC1 via an SLC38A9–Niemann-Pick C1 signaling complex von Castellano, Brian M., Thelen, Ashley M., Moldavski, Ofer, Feltes, McKenna, van der Welle, Reini E. N., Mydock-McGrane, Laurel, Jiang, Xuntian, van Eijkeren, Robert J, Davis, Oliver B., Louie, Sharon M., Perera, Rushika M., Covey, Douglas F., Nomura, Daniel K., Ory, Daniel S., Zoncu, Roberto

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miR-33 links SREBP-2 induction to repression of sterol transporters von Marquart, Tyler J., Allen, Ryan M., Ory, Daniel S., Baldán, Ángel, Sly, William S.

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Chronic cyclodextrin treatment of murine Niemann-Pick C disease ameliorates neuronal cholesterol and glycosphingolipid storage and disease progression von Davidson, Cristin D, Ali, Nafeeza F, Micsenyi, Matthew C, Stephney, Gloria, Renault, Sophie, Dobrenis, Kostantin, Ory, Daniel S, Vanier, Marie T, Walkley, Steven U

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A characterization of Gaucher iPS-derived astrocytes: Potential implications for Parkinson's disease von Aflaki, Elma, Stubblefield, Barbara K., McGlinchey, Ryan P., McMahon, Benjamin, Ory, Daniel S., Sidransky, Ellen

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Small Nucleolar RNAs U32a, U33, and U35a Are Critical Mediators of Metabolic Stress von Michel, Carlos I., Holley, Christopher L., Scruggs, Benjamin S., Sidhu, Rohini, Brookheart, Rita T., Listenberger, Laura L., Behlke, Mark A., Ory, Daniel S., Schaffer, Jean E.

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Monitoring the itinerary of lysosomal cholesterol in Niemann-Pick Type C1-deficient cells after cyclodextrin treatment[S] von Feltes, McKenna, Gale, Sarah E., Moores, Samantha, Ory, Daniel S., Schaffer, Jean E.

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High incidence of unrecognized visceral/neurological late-onset Niemann-Pick disease, type C1, predicted by analysis of massively parallel sequencing data sets von Wassif, Christopher A., Cross, Joanna L., Iben, James, Sanchez-Pulido, Luis, Cougnoux, Antony, Platt, Frances M., Ory, Daniel S., Ponting, Chris P., Bailey-Wilson, Joan E., Biesecker, Leslie G., Porter, Forbes D.

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Reduction of TMEM97 increases NPC1 protein levels and restores cholesterol trafficking in Niemann-pick type C1 disease cells von Ebrahimi-Fakhari, Darius, Wahlster, Lara, Bartz, Fabian, Werenbeck-Ueding, Jennifer, Praggastis, Maria, Zhang, Jessie, Joggerst-Thomalla, Brigitte, Theiss, Susanne, Grimm, Dirk, Ory, Daniel S, Runz, Heiko

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Niemann-Pick Type C Disease Reveals a Link between Lysosomal Cholesterol and PtdIns(4,5)P2 That Regulates Neuronal Excitability von Vivas, Oscar, Tiscione, Scott A., Dixon, Rose E., Ory, Daniel S., Dickson, Eamonn J.

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Impaired Cholesterol Efflux in Senescent Macrophages Promotes Age-Related Macular Degeneration von Sene, Abdoulaye, Khan, Aslam A., Cox, Douglas, Nakamura, Rei E.I., Santeford, Andrea, Kim, Bryan M., Sidhu, Rohini, Onken, Michael D., Harbour, J. William, Hagbi-Levi, Shira, Chowers, Itay, Edwards, Peter A., Baldan, Angel, Parks, John S., Ory, Daniel S., Apte, Rajendra S.

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Palmitate and Lipopolysaccharide Trigger Synergistic Ceramide Production in Primary Macrophages von Schilling, Joel D., Machkovech, Heather M., He, Li, Sidhu, Rohini, Fujiwara, Hideji, Weber, Kassandra, Ory, Daniel S., Schaffer, Jean E.

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Ceramide Remodeling and Risk of Cardiovascular Events and Mortality von Peterson, Linda R., Xanthakis, Vanessa, Duncan, Meredith S., Gross, Stefan, Friedrich, Nele, Völzke, Henry, Felix, Stephan B., Jiang, Hui, Sidhu, Rohini, Nauck, Matthias, Jiang, Xuntian, Ory, Daniel S., Dörr, Marcus, Vasan, Ramachandran S., Schaffer, Jean E.

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Krabbe disease successfully treated via monotherapy of intrathecal gene therapy von Bradbury, Allison M., Bagel, Jessica H., Duc Nguyen, Lykken, Erik A., Salvador, Jill Pesayco, Jiang, Xuntian, Swain, Gary P., Assenmacher, Charles A., Hendricks, Ian J., Miyadera, Keiko, Hess, Rebecka S., Ostrager, Arielle, ODonnell, Patricia, Sands, Mark S., Ory, Daniel S., Shelton, G. Diane, Bongarzone, Ernesto R., Gray, Steven J., Vite, Charles H.

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High-content screen for modifiers of Niemann-Pick type C disease in patient cells von Pugach, Emily K, Feltes, McKenna, Kaufman, Randal J, Ory, Daniel S, Bang, Anne G

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A terpene nucleoside from M. tuberculosis induces lysosomal lipid storage in foamy macrophages von Bedard, Melissa, van der Niet, Sanne, Bernard, Elliott M, Babunovic, Gregory, Cheng, Tan-Yun, Aylan, Beren, Grootemaat, Anita E, Raman, Sahadevan, Botella, Laure, Ishikawa, Eri, O'Sullivan, Mary P, O'Leary, Seónadh, Mayfield, Jacob A, Buter, Jeffrey, Minnaard, Adriaan J, Fortune, Sarah M, Murphy, Leon O, Ory, Daniel S, Keane, Joseph, Yamasaki, Sho, Gutierrez, Maximiliano G, van der Wel, Nicole, Moody, D Branch

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Metabolism of Non-Enzymatically Derived Oxysterols: Clues from sterol metabolic disorders von Griffiths, William J., Yutuc, Eylan, Abdel-Khalik, Jonas, Crick, Peter J., Hearn, Thomas, Dickson, Alison, Bigger, Brian W., Hoi-Yee Wu, Teresa, Goenka, Anu, Ghosh, Arunabha, Jones, Simon A., Covey, Douglas F., Ory, Daniel S., Wang, Yuqin

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Accumulation of alkyl-lysophosphatidylcholines in Niemann-Pick disease type C1 von Mishra, Sonali, Kell, Pamela, Scherrer, David, Dietzen, Dennis J., Vite, Charles H., Berry-Kravis, Elizabeth, Davidson, Cristin, Cologna, Stephanie M., Porter, Forbes D., Ory, Daniel S., Jiang, Xuntian

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A murine Niemann-Pick C1 I1061T knock-in model recapitulates the pathological features of the most prevalent human disease allele von Praggastis, Maria, Tortelli, Brett, Zhang, Jessie, Fujiwara, Hideji, Sidhu, Rohini, Chacko, Anita, Chen, Zhouji, Chung, Chan, Lieberman, Andrew P, Sikora, Jakub, Davidson, Cristin, Walkley, Steven U, Pipalia, Nina H, Maxfield, Frederick R, Schaffer, Jean E, Ory, Daniel S

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The Structural Basis of Cholesterol Accessibility in Membranes von Olsen, Brett N., Bielska, Agata A., Lee, Tiffany, Daily, Michael D., Covey, Douglas F., Schlesinger, Paul H., Baker, Nathan A., Ory, Daniel S.

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