A Randomized Dose-Escalating Phase I Trial of a Replication-Deficient Lymphocytic Choriomeningitis Virus Vector-Based Vaccine Against Human Cytomegalovirus von Schwendinger, Michael, Thiry, Georges, De Vos, Beatrice, Leroux-Roels, Geert, Bruhwyler, Jacques, Huygens, Ariane, Ganeff, Corinne, Buchinger, Heidemarie, Orlinger, Klaus K, Pinschewer, Daniel D, Monath, Thomas P, Lilja, Anders E

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Viral vector-mediated reprogramming of the fibroblastic tumor stroma sustains curative melanoma treatment von Ring, Sandra S., Cupovic, Jovana, Onder, Lucas, Lütge, Mechthild, Perez-Shibayama, Christian, Gil-Cruz, Cristina, Scandella, Elke, De Martin, Angelina, Mörbe, Urs, Hartmann, Fabienne, Wenger, Robert, Spiegl, Matthias, Besse, Andrej, Bonilla, Weldy V., Stemeseder, Felix, Schmidt, Sarah, Orlinger, Klaus K., Krebs, Philippe, Ludewig, Burkhard, Flatz, Lukas

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Flt3 agonist enhances immunogenicity of arenavirus vector-based simian immunodeficiency virus vaccine in macaques von Boopathy, Archana Vidya, Nekkalapudi, Anurag, Sung, Janette, Schulha, Sophie, Jin, Debi, Sharma, Bhawna, Ng, Sarah, Lu, Sabrina, Wimmer, Raphaela, Suthram, Silpa, Ahmadi-Erber, Sarah, Lauterbach, Henning, Orlinger, Klaus K, Hung, Magdeleine, Carr, Brian, Callebaut, Christian, Geleziunas, Romas, Kuhne, Michelle, Schmidt, Sarah, Falkard, Brie

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A replicating LCMV-based vaccine for the treatment of solid tumors von Purde, Mette-Triin, Cupovic, Jovana, Palmowski, Yannick A., Makky, Ahmad, Schmidt, Sarah, Rochwarger, Alexander, Hartmann, Fabienne, Stemeseder, Felix, Lercher, Alexander, Abdou, Marie-Therese, Bomze, David, Besse, Lenka, Berner, Fiamma, Tüting, Thomas, Hölzel, Michael, Bergthaler, Andreas, Kochanek, Stefan, Ludewig, Burkhard, Lauterbach, Henning, Orlinger, Klaus K., Bald, Tobias, Schietinger, Andrea, Schürch, Christian, Ring, Sandra S., Flatz, Lukas

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Development and Characterization of a Novel Non-Lytic Cancer Immunotherapy Using a Recombinant Arenavirus Vector Platform von Lauterbach, Henning, Schmidt, Sarah, Katchar, Kia, Qing, Xiaoping, Iacobucci, Corinne, Hwang, Andy, Schlienger, Katia, Berka, Ursula, Raguz, Josipa, Ahmadi-Erber, Sarah, Schippers, Timo, Stemeseder, Felix, Pinschewer, Daniel D., Matushansky, Igor, Orlinger, Klaus K.

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A Tick-borne Encephalitis Virus Vaccine Based on the European Prototype Strain Induces Broadly Reactive Cross-neutralizing Antibodies in Humans von Orlinger, Klaus K., Hofmeister, Yvonne, Fritz, Richard, Holzer, Georg W., Falkner, Falko G., Unger, Bernd, Loew-Baselli, Alexandra, Poellabauer, Eva-Maria, Ehrlich, Hartmut J., Barrett, P. Noel, Kreil, Thomas R.

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Preclinical evaluation of two phylogenetically distant arenavirus vectors for the development of novel immunotherapeutic combination strategies for cancer treatment von Raguz, Josipa, Pinto, Catarina, Pölzlbauer, Theresa, Habbeddine, Mohamed, Rosskopf, Sandra, Strauß, Judith, Just, Valentin, Schmidt, Sarah, Bidet Huang, Katell, Stemeseder, Felix, Schippers, Timo, Stewart, Ethan, Jez, Jakub, Berraondo, Pedro, Orlinger, Klaus K., Lauterbach, Henning

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Vectors based on modified vaccinia Ankara expressing influenza H5N1 hemagglutinin induce substantial cross-clade protective immunity von Hessel, Annett, Schwendinger, Michael, Holzer, Georg W, Orlinger, Klaus K, Coulibaly, Sogue, Savidis-Dacho, Helga, Zips, Marie-Luise, Crowe, Brian A, Kreil, Thomas R, Ehrlich, Hartmut J, Barrett, P Noel, Falkner, Falko G

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Efficacy of LCMV-based cancer immunotherapies is unleashed by intratumoral injections of polyI:C von Gomar, Celia, Di Trani, Claudia Augusta, Bella, Angela, Arrizabalaga, Leire, Gonzalez-Gomariz, Jose, Fernandez-Sendin, Myriam, Alvarez, Maite, Russo-Cabrera, Joan Salvador, Ardaiz, Nuria, Aranda, Fernando, Schippers, Timo, Quintero, Marisol, Melero, Ignacio, Orlinger, Klaus K, Lauterbach, Henning, Berraondo, Pedro

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Live-attenuated lymphocytic choriomeningitis virus-based vaccines for active immunotherapy of HPV16-positive cancer von Schmidt, Sarah, Bonilla, Weldy V., Reiter, Andrea, Stemeseder, Felix, Kleissner, Theresa, Oeler, Daniel, Berka, Ursula, El-Gazzar, Ahmed, Kiefmann, Bettina, Schulha, Sophie C., Raguz, Josipa, Habbeddine, Mohamed, Scheinost, Marilies, Qing, Xiaoping, Lauterbach, Henning, Matushansky, Igor, Pinschewer, Daniel D., Orlinger, Klaus K.

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Replication-defective lymphocytic choriomeningitis virus vectors expressing guinea pig cytomegalovirus gB and pp65 homologs are protective against congenital guinea pig cytomegalov... von Cardin, Rhonda D, Bravo, Fernando J, Pullum, Derek A, Orlinger, Klaus, Watson, Elizabeth M, Aspoeck, Andreas, Fuhrmann, Gerhard, Guirakhoo, Farshad, Monath, Thomas, Bernstein, David I

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Quantitative comparison of the cross-protection induced by tick-borne encephalitis virus vaccines based on European and Far Eastern virus subtypes von Fritz, Richard, Orlinger, Klaus K, Hofmeister, Yvonne, Janecki, Kathrin, Traweger, Andreas, Perez-Burgos, Laura, Barrett, P. Noel, Kreil, Thomas R

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Additive Protection against Congenital Cytomegalovirus Conferred by Combined Glycoprotein B/pp65 Vaccination Using a Lymphocytic Choriomeningitis Virus Vector von Schleiss, Mark R, Berka, Ursula, Watson, Elizabeth, Aistleithner, Mario, Kiefmann, Bettina, Mangeat, Bastien, Swanson, Elizabeth C, Gillis, Peter A, Hernandez-Alvarado, Nelmary, Fernández-Alarcón, Claudia, Zabeli, Jason C, Pinschewer, Daniel D, Lilja, Anders E, Schwendinger, Michael, Guirakhoo, Farshad, Monath, Thomas P, Orlinger, Klaus K

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Immunogenic arenavirus vector SIV vaccine reduces setpoint viral load in SIV-challenged rhesus monkeys von Boopathy, Archana V., Sharma, Bhawna, Nekkalapudi, Anurag, Wimmer, Raphaela, Gamez-Guerrero, Maria, Suthram, Silpa, Truong, Hoa, Lee, Johnny, Li, Jiani, Martin, Ross, Blair, Wade, Geleziunas, Romas, Orlinger, Klaus, Ahmadi-Erber, Sarah, Lauterbach, Henning, Makadzange, Tariro, Falkard, Brie, Schmidt, Sarah

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Heterologous arenavirus vector prime-boost overrules self-tolerance for efficient tumor-specific CD8 T cell attack von Bonilla, Weldy V., Kirchhammer, Nicole, Marx, Anna-Friederike, Kallert, Sandra M., Krzyzaniak, Magdalena A., Lu, Min, Darbre, Stéphanie, Schmidt, Sarah, Raguz, Josipa, Berka, Ursula, Vincenti, Ilena, Pauzuolis, Mindaugas, Kerber, Romy, Hoepner, Sabine, Günther, Stephan, Magnus, Carsten, Merkler, Doron, Orlinger, Klaus K., Zippelius, Alfred, Pinschewer, Daniel D.

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Arenavirus-Based Vectors Generate Robust SIV Immunity in Non-Human Primates von Sharma, Bhawna, Bekerman, Elena, Truong, Hoa, Lee, Johnny, Gamez-Guerrero, Maria, Boopathy, Archana, Mital, Rohit, Huang, Katell Bidet, Ahmadi-Erber, Sarah, Wimmer, Raphaela, Schulha, Sophie, Lauterbach, Henning, Orlinger, Klaus, Suthram, Silpa, Lewis, Mark G, Blair, Wade, Makadzange, Tariro, Geleziunas, Romas, Murry, Jeffrey P, Schmidt, Sarah

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679 Characterization of tumor specific CD8+ T cell responses in patients with recurrent/metastatic HPV16-positive head and neck cancer receiving HB-200 monotherapy as second or lat... von Ho, Alan L, Pearson, Alexander T, Fu, Siqing, Posner, Marshall R, Adkins, Douglas, Nabell, Lisle, Niu, Jiaxin, Richardson, Debra L, Leidner, Rom S, Chung, Ki, Laux, Douglas, Nieva, Jorge, Wong, Stuart, Rojas, Katerin, Rosenberg, Ari J, Phan, Minh, Kaufmann, Trisha, Plescia, Christopher, Qing, Xiaoping, Iacobucci, Corinne, Tchakov, Ilian, Katchar, Kia, Orlinger, Klaus, Schlienger, Katia, Pfister, David G

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Analysis of the effects of alterations in the tick-borne encephalitis virus 3′-noncoding region on translation and RNA replication using reporter replicons von Hoenninger, Verena M, Rouha, Harald, Orlinger, Klaus K, Miorin, Lisa, Marcello, Alessandro, Kofler, Regina M, Mandl, Christian W

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Construction and Mutagenesis of an Artificial Bicistronic Tick-Borne Encephalitis Virus Genome Reveals an Essential Function of the Second Transmembrane Region of Protein E in Flav... von ORLINGER, Klaus K, HOENNINGER, Verena M, KOFLER, Regina M, MANDL, Christian W

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An inactivated West Nile Virus vaccine derived from a chemically synthesized cDNA system von Orlinger, Klaus K, Holzer, Georg W, Schwaiger, Julia, Mayrhofer, Josef, Schmid, Karl, Kistner, Otfried, Noel Barrett, P, Falkner, Falko G

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