Generating functional protein variants with variational autoencoders von Hawkins-Hooker, Alex, Depardieu, Florence, Baur, Sebastien, Couairon, Guillaume, Chen, Arthur, Bikard, David

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An analysis of tissue-specific alternative splicing at the protein level von Rodriguez, Jose Manuel, Pozo, Fernando, di Domenico, Tomas, Vazquez, Jesus, Tress, Michael L

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Alpha Helices Are More Robust to Mutations than Beta Strands von Abrusán, György, Marsh, Joseph A

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An Ancient Fingerprint Indicates the Common Ancestry of Rossmann-Fold Enzymes Utilizing Different Ribose-Based Cofactors von Laurino, Paola, Tóth-Petróczy, Ágnes, Meana-Pañeda, Rubén, Lin, Wei, Truhlar, Donald G, Tawfik, Dan S

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A Novel Group of Dynamin-Related Proteins Shared by Eukaryotes and Giant Viruses Is Able to Remodel Mitochondria From Within the Matrix von Sheikh, Shaghayegh, Pánek, Tomáš, Gahura, Ondřej, Týč, Jiří, Záhonová, Kristína, Lukeš, Julius, Eliáš, Marek, Hashimi, Hassan

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The complexity of protein interactions unravelled from structural disorder von Seoane, Beatriz, Carbone, Alessandra

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Diversity and distribution of nuclease bacteriocins in bacterial genomes revealed using Hidden Markov Models von Sharp, Connor, Bray, James, Housden, Nicholas G, Maiden, Martin C J, Kleanthous, Colin

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Biases in the experimental annotations of protein function and their effect on our understanding of protein function space von Schnoes, Alexandra M, Ream, David C, Thorman, Alexander W, Babbitt, Patricia C, Friedberg, Iddo

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Systematic Mapping of Protein Mutational Space by Prolonged Drift Reveals the Deleterious Effects of Seemingly Neutral Mutations von Rockah-Shmuel, Liat, Tóth-Petróczy, Ágnes, Tawfik, Dan S

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Conformational diversity analysis reveals three functional mechanisms in proteins von Monzon, Alexander Miguel, Zea, Diego Javier, Fornasari, María Silvina, Saldaño, Tadeo E, Fernandez-Alberti, Sebastian, Tosatto, Silvio C E, Parisi, Gustavo

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Determining effects of non-synonymous SNPs on protein-protein interactions using supervised and semi-supervised learning von Zhao, Nan, Han, Jing Ginger, Shyu, Chi-Ren, Korkin, Dmitry

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Quantitative profiling of protease specificity von Ratnikov, Boris I, Cieplak, Piotr, Remacle, Albert G, Nguyen, Elise, Smith, Jeffrey W

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Exploring the composition of protein-ligand binding sites on a large scale von Khazanov, Nickolay A, Carlson, Heather A

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Global patterns of protein domain gain and loss in superkingdoms von Nasir, Arshan, Kim, Kyung Mo, Caetano-Anollés, Gustavo

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Structural and Energetic Characterization of the Ankyrin Repeat Protein Family von Parra, R Gonzalo, Espada, Rocío, Verstraete, Nina, Ferreiro, Diego U

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An Atlas of Peroxiredoxins Created Using an Active Site Profile-Based Approach to Functionally Relevant Clustering of Proteins von Harper, Angela F, Leuthaeuser, Janelle B, Babbitt, Patricia C, Morris, John H, Ferrin, Thomas E, Poole, Leslie B, Fetrow, Jacquelyn S

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Functional Basis of Microorganism Classification von Zhu, Chengsheng, Delmont, Tom O, Vogel, Timothy M, Bromberg, Yana

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Polymorphic sites preferentially avoid co-evolving residues in MHC class I proteins von Dib, Linda, Salamin, Nicolas, Gfeller, David

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Recognition of sites of functional specialisation in all known eukaryotic protein kinase families von Kalaivani, Raju, Reema, Raju, Srinivasan, Narayanaswamy

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Bayesian Top-Down Protein Sequence Alignment with Inferred Position-Specific Gap Penalties von Neuwald, Andrew F, Altschul, Stephen F

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