ZNF131 suppresses centrosome fragmentation in glioblastoma stem-like cells through regulation of HAUS5 von Ding, Yu, Herman, Jacob A., Toledo, Chad M., Lang, Jackie M., Corrin, Philip, Girard, Emily J., Basom, Ryan, Delrow, Jeffrey J., Olson, James M., Paddison, Patrick J.

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HDAC and PI3K Antagonists Cooperate to Inhibit Growth of MYC-Driven Medulloblastoma von Pei, Yanxin, Liu, Kun-Wei, Wang, Jun, Garancher, Alexandra, Tao, Ran, Esparza, Lourdes A., Maier, Donna L., Udaka, Yoko T., Murad, Najiba, Morrissy, Sorana, Seker-Cin, Huriye, Brabetz, Sebastian, Qi, Lin, Kogiso, Mari, Schubert, Simone, Olson, James M., Cho, Yoon-Jae, Li, Xiao-Nan, Crawford, John R., Levy, Michael L., Kool, Marcel, Pfister, Stefan M., Taylor, Michael D., Wechsler-Reya, Robert J.

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Design of Highly Emissive Polymer Dot Bioconjugates for In Vivo Tumor Targeting von Wu, Changfeng, Hansen, Stacey J., Hou, Qiong, Yu, Jiangbo, Zeigler, Maxwell, Jin, Yuhui, Burnham, Daniel R., McNeill, Jason D., Olson, James M., Chiu, Daniel T.

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Integrative Genomic Analysis of Medulloblastoma Identifies a Molecular Subgroup That Drives Poor Clinical Outcome von CHO, Yoon-Jae, TSHERNIAK, Aviad, LAU, Ching C, OLSON, James M, GILBERTSON, Richard I, GAJJAR, Amar, DELATTRE, Olivier, KOOL, Marcel, LIGON, Keith, MEYERSON, Matthew, MESIROV, Jill P, POMEROY, Scott L, TAMAYO, Pablo, SANTAGATA, Sandro, LIGON, Azra, GREULICH, Heidi, BERHOUKIM, Rameen, AMANI, Vladimir, GOUMNEROVA, Liliana, EBERHART, Charles G

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Curcumin-induced HDAC inhibition and attenuation of medulloblastoma growth in vitro and in vivo von Lee, Seung Joon, Krauthauser, Candice, Maduskuie, Victoria, Fawcett, Paul T, Olson, James M, Rajasekaran, Sigrid A

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Pemetrexed and Gemcitabine as Combination Therapy for the Treatment of Group3 Medulloblastoma von Morfouace, Marie, Shelat, Anang, Jacus, Megan, Freeman, Burgess B., Turner, David, Robinson, Sarah, Zindy, Frederique, Wang, Yong-Dong, Finkelstein, David, Ayrault, Olivier, Bihannic, Laure, Puget, Stephanie, Li, Xiao-Nan, Olson, James M., Robinson, Giles W., Guy, R. Kiplin, Stewart, Clinton F., Gajjar, Amar, Roussel, Martine F.

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PEI-PEG-Chitosan-Copolymer-Coated Iron Oxide Nanoparticles for Safe Gene Delivery: Synthesis, Complexation, and Transfection von Kievit, Forrest M., Veiseh, Omid, Bhattarai, Narayan, Fang, Chen, Gunn, Jonathan W., Lee, Donghoon, Ellenbogen, Richard G., Olson, James M., Zhang, Miqin

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Mammalian display screening of diverse cystine-dense peptides for difficult to drug targets von Crook, Zachary R., Sevilla, Gregory P., Friend, Della, Brusniak, Mi-Youn, Bandaranayake, Ashok D., Clarke, Midori, Gewe, Mesfin, Mhyre, Andrew J., Baker, David, Strong, Roland K., Bradley, Philip, Olson, James M.

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Inhibition of CDK4/6 by Palbociclib Significantly Extends Survival in Medulloblastoma Patient-Derived Xenograft Mouse Models von Cook Sangar, Michelle L, Genovesi, Laura A, Nakamoto, Madison W, Davis, Melissa J, Knobluagh, Sue E, Ji, Pengxiang, Millar, Amanda, Wainwright, Brandon J, Olson, James M

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Genome-Wide Analyses Identify Recurrent Amplifications of Receptor Tyrosine Kinases and Cell-Cycle Regulatory Genes in Diffuse Intrinsic Pontine Glioma von PAUGH, Barbara S, BRONISCER, Alberto, ONAR-THOMAS, Arzu, BAKER, Justin N, GAJJAR, Amar, ELLISON, David W, BAKER, Suzanne J, CHUNXU QU, MILLER, Claudia P, JUNYUAN ZHANG, TATEVOSSIAN, Ruth G, OLSON, James M, GEYER, J. Russell, CHI, Susan N, DA SILVA, Nasjla Saba

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CYpHER: catalytic extracellular targeted protein degradation with high potency and durable effect von Crook, Zachary R., Sevilla, Gregory P., Young, Pamela, Girard, Emily J., Phi, Tinh-Doan, Howard, Monique L., Price, Jason, Olson, James M., Nairn, Natalie W.

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Histone deposition pathways determine the chromatin landscapes of H3.1 and H3.3 K27M oncohistones von Sarthy, Jay F, Meers, Michael P, Janssens, Derek H, Henikoff, Jorja G, Feldman, Heather, Paddison, Patrick J, Lockwood, Christina M, Vitanza, Nicholas A, Olson, James M, Ahmad, Kami, Henikoff, Steven

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Therapeutic Opportunities for Medulloblastoma Come of Age von Olson, James M.

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Genome-wide RNAi screens in human brain tumor isolates reveal a novel viability requirement for PHF5A von Hubert, Christopher G, Bradley, Robert K, Ding, Yu, Toledo, Chad M, Herman, Jacob, Skutt-Kakaria, Kyobi, Girard, Emily J, Davison, Jerry, Berndt, Jason, Corrin, Philip, Hardcastle, Justin, Basom, Ryan, Delrow, Jeffery J, Webb, Thomas, Pollard, Steven M, Lee, Jeongwu, Olson, James M, Paddison, Patrick J

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Tumor paint: a chlorotoxin : Cy5.5 bioconjugate for intraoperative visualization of cancer foci von VEISEH, Mandana, GABIKIAN, Patrik, KWOK, Deborah, MUNOZ, Nina M, SZE, Raymond W, GRADY, William M, GREENBERG, Norman M, ELLENBOGEN, Richard G, OLSONL, James M, BAHRAMI, S-Bahram, VEISEH, Omid, MIQIN ZHANG, HACKMAN, Robert C, RAVANPAY, Ali C, STROUD, Mark R, KUSUMA, Yumiko, HANSEN, Stacey J

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Laboratory information management software for engineered mini-protein therapeutic workflow von Brusniak, Mi-Youn, Ramos, Hector, Lee, Bernard, Olson, James M

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Therapeutic HDAC inhibition in hypermutant diffuse intrinsic pontine glioma von Noll, Alyssa, Myers, Carrie, Biery, Matthew C, Meechan, Michael, Tahiri, Sophie, Rajendran, Asmitha, Berens, Michael E, Paine, Danyelle, Byron, Sara, Zhang, Jiaming, Winter, Conrad, Pakiam, Fiona, Leary, Sarah E S, Cole, Bonnie L, Jackson, Evangeline R, Dun, Matthew D, Foster, Jessica B, Evans, Myron K, Pattwell, Siobhan S, Olson, James M, Vitanza, Nicholas A

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Hedgehog pathway inhibitor saridegib (IPI-926) increases lifespan in a mouse medulloblastoma model von Lee, Michelle J, Hatton, Beryl A, Villavicencio, Elisabeth H, Khanna, Paritosh C, Friedman, Seth D, Ditzler, Sally, Pullar, Barbara, Robison, Keith, White, Kerry F, Tunkey, Chris, LeBlanc, Michael, Randolph-Habecker, Julie, Knoblaugh, Sue E, Hansen, Stacey, Richards, Andrew, Wainwright, Brandon J, McGovern, Karen, Olson, James M

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Medulloblastoma Growth Inhibition by Hedgehog Pathway Blockade von Berman, David M., Karhadkar, Sunil S., Hallahan, Andrew R., Pritchard, Joel I., Eberhart, Charles G., Watkins, D. Neil, Chen, James K., Cooper, Michael K., Taipale, Jussi, Olson, James M., Beachy, Philip A.

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Automated in situ chromatin profiling efficiently resolves cell types and gene regulatory programs von Janssens, Derek H, Wu, Steven J, Sarthy, Jay F, Meers, Michael P, Myers, Carrie H, Olson, James M, Ahmad, Kami, Henikoff, Steven

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