Terpene Biosynthesis: Modularity Rules von Oldfield, Eric, Lin, Fu-Yang

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The Mevalonate Pathway Is a Druggable Target for Vaccine Adjuvant Discovery von Xia, Yun, Xie, Yonghua, Yu, Zhengsen, Xiao, Hongying, Jiang, Guimei, Zhou, Xiaoying, Yang, Yunyun, Li, Xin, Zhao, Meng, Li, Liping, Zheng, Mingke, Han, Shuai, Zong, Zhaoyun, Meng, Xianbin, Deng, Haiteng, Ye, Huahu, Fa, Yunzhi, Wu, Haitao, Oldfield, Eric, Hu, Xiaoyu, Liu, Wanli, Shi, Yan, Zhang, Yonghui

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A Highly Efficient Single-Chain Metal–Organic Nanoparticle Catalyst for Alkyne–Azide “Click” Reactions in Water and in Cells von Bai, Yugang, Feng, Xinxin, Xing, Hang, Xu, Yanhua, Kim, Boo Kyung, Baig, Noman, Zhou, Tianhui, Gewirth, Andrew A, Lu, Yi, Oldfield, Eric, Zimmerman, Steven C

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Antiinfectives targeting enzymes and the proton motive force von Feng, Xinxin, Zhu, Wei, Schurig-Briccio, Lici A., Lindert, Steffen, Shoen, Carolyn, Hitchings, Reese, Li, Jikun, Wang, Yang, Baig, Noman, Zhou, Tianhui, Kim, Boo Kyung, Crick, Dean C., Cynamon, Michael, McCammon, J. Andrew, Gennis, Robert B., Oldfield, Eric

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Multitarget Drug Discovery for Tuberculosis and Other Infectious Diseases von Li, Kai, Schurig-Briccio, Lici A, Feng, Xinxin, Upadhyay, Ashutosh, Pujari, Venugopal, Lechartier, Benoit, Fontes, Fabio L, Yang, Hongliang, Rao, Guodong, Zhu, Wei, Gulati, Anmol, No, Joo Hwan, Cintra, Giovana, Bogue, Shannon, Liu, Yi-Liang, Molohon, Katie, Orlean, Peter, Mitchell, Douglas A, Freitas-Junior, Lucio, Ren, Feifei, Sun, Hong, Jiang, Tong, Li, Yujie, Guo, Rey-Ting, Cole, Stewart T, Gennis, Robert B, Crick, Dean C, Oldfield, Eric

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Antagonism screen for inhibitors of bacterial cell wall biogenesis uncovers an inhibitor of undecaprenyl diphosphate synthase von Farha, Maya A., Czarny, Tomasz L., Myers, Cullen L., Worrall, Liam J., French, Shawn, Conrady, Deborah G., Wang, Yang, Oldfield, Eric, Strynadka, Natalie C. J., Brown, Eric D.

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Lipophilic bisphosphonates reduced cyst burden and ameliorated hyperactivity of mice chronically infected with Toxoplasma gondii von Sleda, Melissa A, Pitafi, Zaid F, Song, WenZhan, Oldfield, Eric, Moreno, Silvia N J

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Phenylthiazole Antibacterial Agents Targeting Cell Wall Synthesis Exhibit Potent Activity in Vitro and in Vivo against Vancomycin-Resistant Enterococci von Mohammad, Haroon, Younis, Waleed, Chen, Lu, Peters, Christine E, Pogliano, Joe, Pogliano, Kit, Cooper, Bruce, Zhang, Jianan, Mayhoub, Abdelrahman, Oldfield, Eric, Cushman, Mark, Seleem, Mohamed N

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Human Platelet Dense Granules Contain Polyphosphate and Are Similar to Acidocalcisomes of Bacteria and Unicellular Eukaryotes von Ruiz, Felix A, Lea, Christopher R, Oldfield, Eric, Docampo, Roberto

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Thermodynamics of Bisphosphonates Binding to Human Bone: A Two-Site Model von Mukherjee, Sujoy, Huang, Cancan, Guerra, Francisco, Wang, Ke, Oldfield, Eric

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Reduced cell proliferation by IKK2 depletion in a mouse lung-cancer model von Xia, Yifeng, Yeddula, Narayana, Leblanc, Mathias, Ke, Eugene, Zhang, Yonghui, Oldfield, Eric, Shaw, Reuben J., Verma, Inder M.

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The Chemical Nature of Hydrogen Bonding in Proteins via NMR:  J-Couplings, Chemical Shifts, and AIM Theory von Arnold, William D, Oldfield, Eric

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Distinct Energy-Coupling Factor Transporter Subunits Enable Flavin Acquisition and Extracytosolic Trafficking for Extracellular Electron Transfer in Listeria monocytogenes von Rivera-Lugo, Rafael, Huang, Shuo, Lee, Frank, Méheust, Raphaël, Iavarone, Anthony T, Sidebottom, Ashley M, Oldfield, Eric, Portnoy, Daniel A, Light, Samuel H

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Bisphosphonate-Generated ATP-Analogs Inhibit Cell Signaling Pathways von Malwal, Satish R, O’Dowd, Bing, Feng, Xinxin, Turhanen, Petri, Shin, Christopher, Yao, Jiaqi, Kim, Boo Kyung, Baig, Noman, Zhou, Tianhui, Bansal, Sandhya, Khade, Rahul L, Zhang, Yong, Oldfield, Eric

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Tetra- to Dodecanuclear Oxomolybdate Complexes with Functionalized Bisphosphonate Ligands: Activity in Killing Tumor Cells von Compain, Jean-Daniel, Mialane, Pierre, Marrot, Jérôme, Sécheresse, Francis, Zhu, Wei, Oldfield , Eric, Dolbecq, Anne

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Resistance-resistant antibiotics von Oldfield, Eric, Feng, Xinxin

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Ultrahigh resolution protein structures using NMR chemical shift tensors von Wylie, Benjamin J, Sperling, Lindsay J, Nieuwkoop, Andrew J, Franks, W. Trent, Oldfield, Eric, Rienstra, Chad M

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Antibacterial Drug Leads: DNA and Enzyme Multitargeting von Zhu, Wei, Wang, Yang, Li, Kai, Gao, Jian, Huang, Chun-Hsiang, Chen, Chun-Chi, Ko, Tzu-Ping, Zhang, Yonghui, Guo, Rey-Ting, Oldfield, Eric

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The Heptaprenyl Diphosphate Synthase (Coq1) Is the Target of a Lipophilic Bisphosphonate That Protects Mice against Toxoplasma gondii Infection von Sleda, Melissa A, Li, Zhu-Hong, Behera, Ranjan, Baierna, Baihetiya, Li, Catherine, Jumpathong, Jomkwan, Malwal, Satish R, Kawamukai, Makoto, Oldfield, Eric, Moreno, Silvia N J

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Isoprenoid Biosynthesis Inhibitors Targeting Bacterial Cell Growth von Desai, Janish, Wang, Yang, Wang, Ke, Malwal, Satish R., Oldfield, Eric

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