The role of sphingomyelin and sphingomyelin synthases in cell death, proliferation and migration—from cell and animal models to human disorders von Taniguchi, Makoto, Okazaki, Toshiro

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Sphingomyelin synthase 2 deficiency inhibits the induction of murine colitis‐associated colon cancer von Ohnishi, Toshio, Hashizume, Chieko, Taniguchi, Makoto, Furumoto, Hidehiro, Han, Jia, Gao, Rongfen, Kinami, Shinichi, Kosaka, Takeo, Okazaki, Toshiro

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Ceramide/Sphingomyelin Rheostat Regulated by Sphingomyelin Synthases and Chronic Diseases in Murine Models von Taniguchi, Makoto, Okazaki, Toshiro

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Analysis of lipid-composition changes in plasma membrane microdomains[S] von Ogiso, Hideo, Taniguchi, Makoto, Okazaki, Toshiro

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Deficiency of sphingomyelin synthase 1 but not sphingomyelin synthase 2 reduces bone formation due to impaired osteoblast differentiation von Matsumoto, Goichi, Hashizume, Chieko, Watanabe, Ken, Taniguchi, Makoto, Okazaki, Toshiro

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Ceramide Metabolism Regulated by Sphingomyelin Synthase 2 Is Associated with Acquisition of Chemoresistance via Exosomes in Human Leukemia Cells von Taniguchi, Makoto, Nagaya, Shingo, Yuyama, Kohei, Kotani, Ai, Igarashi, Yasuyuki, Okazaki, Toshiro

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Plasma membrane sphingomyelin modulates thymocyte development by inhibiting TCR-induced apoptosis von Toshima, Kaoru, Nagafuku, Masakazu, Okazaki, Toshiro, Kobayashi, Toshihide, Inokuchi, Jin-ichi

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Role of ceramide/sphingomyelin (SM) balance regulated through “SM cycle” in cancer von Taniguchi, Makoto, Okazaki, Toshiro

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Dynamic Modification of Sphingomyelin in Lipid Microdomains Controls Development of Obesity, Fatty Liver, and Type 2 Diabetes von Mitsutake, Susumu, Zama, Kota, Yokota, Hazuki, Yoshida, Tetsuya, Tanaka, Miki, Mitsui, Masaru, Ikawa, Masahito, Okabe, Masaru, Tanaka, Yoshikazu, Yamashita, Tadashi, Takemoto, Hiroshi, Okazaki, Toshiro, Watanabe, Ken, Igarashi, Yasuyuki

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Deficiency of sphingomyelin synthase 2 prolongs survival by the inhibition of lymphoma infiltration through ICAM‐1 reduction von Taniguchi, Makoto, Ueda, Yoshibumi, Matsushita, Michiko, Nagaya, Shingo, Hashizume, Chieko, Arai, Kenta, Kabayama, Kazuya, Fukase, Koichi, Watanabe, Ken, Wardhani, Lusi Oka, Hayashi, Kazuhiko, Okazaki, Toshiro

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Sphingomyelin in microdomains of the plasma membrane regulates amino acid‐stimulated mTOR signal activation von Zama, Kota, Mitsutake, Susumu, Okazaki, Toshiro, Igarashi, Yasuyuki

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Epidermal permeability barrier function and sphingolipid content in the skin of sphingomyelin synthase 2 deficient mice von Nomoto, Koji, Itaya, Yurina, Watanabe, Ken, Yamashita, Tadashi, Okazaki, Toshiro, Tokudome, Yoshihiro

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Comparative lipid analysis in the normal and cancerous organoids of MDCK cells von Yoshizaki, Hisayoshi, Ogiso, Hideo, Okazaki, Toshiro, Kiyokawa, Etsuko

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Tissue-selective alteration of ethanolamine plasmalogen metabolism in dedifferentiated colon mucosa von Lopez, Daniel H., Bestard-Escalas, Joan, Garate, Jone, Maimó-Barceló, Albert, Fernández, Roberto, Reigada, Rebeca, Khorrami, Sam, Ginard, Daniel, Okazaki, Toshiro, Fernández, José A., Barceló-Coblijn, Gwendolyn

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Mitochondrial Dysfunction and Increased Reactive Oxygen Species Impair Insulin Secretion in Sphingomyelin Synthase 1-null Mice von Yano, Masato, Watanabe, Ken, Yamamoto, Tadashi, Ikeda, Kazutaka, Senokuchi, Takafumi, Lu, Meihong, Kadomatsu, Tsuyoshi, Tsukano, Hiroto, Ikawa, Masahito, Okabe, Masaru, Yamaoka, Shohei, Okazaki, Toshiro, Umehara, Hisanori, Gotoh, Tomomi, Song, Wen-Jie, Node, Koichi, Taguchi, Ryo, Yamagata, Kazuya, Oike, Yuichi

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Differential changes in sphingolipids between TNF-induced necroptosis and apoptosis in U937 cells and necroptosis-resistant sublines von Sawai, Hirofumi, Ogiso, Hideo, Okazaki, Toshiro

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Knockdown of sphingomyelin synthase 2 inhibits osteoclastogenesis by decreasing RANKL expression in mouse primary osteoblasts von YOSHIKAWA, Yoshihiro, YOSHIZAWA, Tatsuya, DOMAE, Eisuke, HIRAI, Yuya, KAMADA, Aiko, OKAZAKI, Toshiro, IKEO, Takashi

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Deficient Leptin Signaling Ameliorates Systemic Lupus Erythematosus Lesions in MRL/Mp- Faslpr Mice von Fujita, Yoshimasa, Fujii, Takao, Mimori, Tsuneyo, Sato, Tomomi, Nakamura, Takuji, Iwao, Haruka, Nakajima, Akio, Miki, Miyuki, Sakai, Tomoyuki, Kawanami, Takafumi, Tanaka, Masao, Masaki, Yasufumi, Fukushima, Toshihiro, Okazaki, Toshiro, Umehara, Hisanori

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Role of Sphingolipids and Metabolizing Enzymes in Hematological Malignancies von Kitatani, K., Tohoku Medical Megabank Organization, Sendai, Japan, Taniguchi, M., Kanazawa Medical University, Uchinada, Japan, Okazaki, T., Kanazawa Medical University, Uchinada, Japan

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Regulation of Cell Migration by Sphingomyelin Synthases: Sphingomyelin in Lipid Rafts Decreases Responsiveness to Signaling by the CXCL12/CXCR4 Pathway von Asano, Satoshi, Kitatani, Kazuyuki, Taniguchi, Makoto, Hashimoto, Mayumi, Zama, Kota, Mitsutake, Susumu, Igarashi, Yasuyuki, Takeya, Hiroyuki, Kigawa, Junzo, Hayashi, Akira, Umehara, Hisanori, Okazaki, Toshiro

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