Exosomal miR-135b shed from hypoxic multiple myeloma cells enhances angiogenesis by targeting factor-inhibiting HIF-1 von Umezu, Tomohiro, Tadokoro, Hiroko, Azuma, Kenko, Yoshizawa, Seiichiro, Ohyashiki, Kazuma, Ohyashiki, Junko H.

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Extracellular vesicle-mediated cell–cell communication in haematological neoplasms von Ohyashiki, Junko H., Umezu, Tomohiro, Ohyashiki, Kazuma

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Genetic Variants in C5 and Poor Response to Eculizumab von Nishimura, Jun-ichi, Yamamoto, Masaki, Hayashi, Shin, Ohyashiki, Kazuma, Ando, Kiyoshi, Brodsky, Andres L, Noji, Hideyoshi, Kitamura, Kunio, Eto, Tetsuya, Takahashi, Toru, Masuko, Masayoshi, Matsumoto, Takuro, Wano, Yuji, Shichishima, Tsutomu, Shibayama, Hirohiko, Hase, Masakazu, Li, Lan, Johnson, Krista, Lazarowski, Alberto, Tamburini, Paul, Inazawa, Johji, Kinoshita, Taroh, Kanakura, Yuzuru

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The oral iron chelator deferasirox represses signaling through the mTOR in myeloid leukemia cells by enhancing expression of REDD1 von Ohyashiki, Junko H., Kobayashi, Chiaki, Hamamura, Ryoko, Okabe, Seiichi, Tauchi, Tetsuzo, Ohyashiki, Kazuma

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Lineage-specific RUNX2 super-enhancer activates MYC and promotes the development of blastic plasmacytoid dendritic cell neoplasm von Kubota, Sho, Tokunaga, Kenji, Umezu, Tomohiro, Yokomizo-Nakano, Takako, Sun, Yuqi, Oshima, Motohiko, Tan, Kar Tong, Yang, Henry, Kanai, Akinori, Iwanaga, Eisaku, Asou, Norio, Maeda, Takahiro, Nakagata, Naomi, Iwama, Atsushi, Ohyashiki, Kazuma, Osato, Motomi, Sashida, Goro

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Down-regulation of miR-92 in human plasma is a novel marker for acute leukemia patients von Tanaka, Masami, Oikawa, Kosuke, Takanashi, Masakatsu, Kudo, Motoshige, Ohyashiki, Junko, Ohyashiki, Kazuma, Kuroda, Masahiko

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New Comprehensive Cytogenetic Scoring System for Primary Myelodysplastic Syndromes (MDS) and Oligoblastic Acute Myeloid Leukemia After MDS Derived From an International Database Me... von SCHANZ, Julie, TÜCHLER, Heinz, STEIDL, Christian, FONATSCH, Christa, PFEILSTÖCKER, Michael, NÖSSLINGER, Thomas, VALENT, Peter, GIAGOUNIDIS, Aristoteles, AUL, Carlo, LÜBBERT, Michael, STAUDER, Reinhard, KRIEGER, Otto, SOLE, Francesc, GARCIA-MANERO, Guillermo, FADERL, Stefan, PIERCE, Sherry, LE BEAU, Michelle M, BENNETT, John M, GREENBERG, Peter, GERMING, Ulrich, HAASE, Detlef, MALLO, Mar, LUNO, Elisa, CERVERA, José, GRANADA, Isabel, HILDEBRANDT, Barbara, SLOVAK, Marilyn L, OHYASHIKI, Kazuma

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Effect of the extracellular component of bone marrow mesenchymal stromal cells from healthy donors on hematologic neoplasms and their angiogenesis von Gladkova, Nina, Umezu, Tomohiro, Imanishi, Satoshi, Kawana, Chiaki, Ohyashiki, Junko H., Ohyashiki, Kazuma

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Potential of a sphingosine 1‑phosphate receptor antagonist and sphingosine kinase inhibitors as targets for multiple myeloma treatment von Tanaka, Yuko, Okabe, Seiichi, Ohyashiki, Kazuma, Gotoh, Akihiko

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Clinical impact of down-regulated plasma miR-92a levels in non-Hodgkin's lymphoma von Ohyashiki, Kazuma, Umezu, Tomohiro, Yoshizawa, Sei-Ichiro, Ito, Yoshikazu, Ohyashiki, Michiyo, Kawashima, Hisashi, Tanaka, Masami, Kuroda, Masahiko, Ohyashiki, Junko H

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Exosomal miRNA Signatures for Late-Onset Acute Graft-Versus-Host Disease in Allogenic Hematopoietic Stem Cell Transplantation von Yoshizawa, Seiichiro, Umezu, Tomohiro, Saitoh, Yuu, Gotoh, Moritaka, Akahane, Daigo, Kobayashi, Chiaki, Ohyashiki, Junko H, Ohyashiki, Kazuma

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Sustained upregulation of effector natural killer cells in chronic myeloid leukemia after discontinuation of imatinib von Mizoguchi, Izuru, Yoshimoto, Takayuki, Katagiri, Seiichiro, Mizuguchi, Junichiro, Tauchi, Tetsuzo, Kimura, Yukihiko, Inokuchi, Koiti, Ohyashiki, Junko H., Ohyashiki, Kazuma

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Replenishing exosomes from older bone marrow stromal cells with miR-340 inhibits myeloma-related angiogenesis von Umezu, Tomohiro, Imanishi, Satoshi, Azuma, Kenko, Kobayashi, Chiaki, Yoshizawa, Seiichiro, Ohyashiki, Kazuma, Ohyashiki, Junko H.

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Therapeutic targeting of Aurora A kinase in Philadelphia chromosome-positive ABL tyrosine kinase inhibitor-resistant cells von Okabe, Seiichi, Tauchi, Tetsuzo, Tanaka, Yuko, Ohyashiki, Kazuma

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Phase 1/2 study of the WT1 peptide cancer vaccine WT4869 in patients with myelodysplastic syndrome von Ueda, Yasunori, Ogura, Michinori, Miyakoshi, Shigesaburo, Suzuki, Takahiro, Heike, Yuji, Tagashira, Shuzo, Tsuchiya, Satoru, Ohyashiki, Kazuma, Miyazaki, Yasushi

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Activity of a novel G-quadruplex-interactive telomerase inhibitor, telomestatin (SOT-095), against human leukemia cells: involvement of ATM-dependent DNA damage response pathways von TAUCHI, Tetsuzo, SHIN-YA, Kazuo, SASHIDA, Goro, SUMI, Masahiko, NAKAJIMA, Akihiro, SHIMAMOTO, Takashi, OHYASHIKI, Junko H, OHYASHIKI, Kazuma

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Poly (ADP-ribose) polymerase inhibitors selectively induce cytotoxicity in TCF3-HLF–positive leukemic cells von Piao, Jinhua, Takai, Shiori, Kamiya, Takahiro, Inukai, Takeshi, Sugita, Kanji, Ohyashiki, Kazuma, Delia, Domenico, Masutani, Mitsuko, Mizutani, Shuki, Takagi, Masatoshi

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Predisposed genomic instability in pre-treatment bone marrow evolves to therapy -related myeloid neoplasms in malignant lymphoma von Katagiri, Seiichiro, Makishima, Hideki, Azuma, Kenko, Nannya, Yasuhito, Saitoh, Yuu, Yoshizawa, Seiichiro, Akahane, Daigo, Fujimoto, Hiroaki, Ito, Yoshikazu, Velaga, Ravi, Umezu, Tomohiro, Ohyashiki, Junko H., Ogawa, Seishi, Ohyashiki, Kazuma

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Overexpression of RUNX3 Represses RUNX1 to Drive Transformation of Myelodysplastic Syndrome von Yokomizo-Nakano, Takako, Kubota, Sho, Bai, Jie, Hamashima, Ai, Morii, Mariko, Sun, Yuqi, Katagiri, Seiichiro, Iimori, Mihoko, Kanai, Akinori, Tanaka, Daiki, Oshima, Motohiko, Harada, Yuka, Ohyashiki, Kazuma, Iwama, Atsushi, Harada, Hironori, Osato, Motomi, Sashida, Goro

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Treatment-free remission after first-line dasatinib treatment in patients with chronic myeloid leukemia in the chronic phase: the D-NewS Study of the Kanto CML Study Group von Yamaguchi, Hiroki, Takezako, Naoki, Ohashi, Kazuteru, Oba, Koji, Kumagai, Takashi, Kozai, Yasuji, Wakita, Hisashi, Yamamoto, Koh, Fujita, Akira, Igarashi, Tadahiko, Yoshida, Chikashi, Ohyashiki, Kazuma, Okamoto, Shinichiro, Sakamoto, Junichi, Sakamaki, Hisashi, Inokuchi, Koiti

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