PERK as a hub of multiple pathogenic pathways leading to memory deficits and neurodegeneration in Alzheimer’s disease von Ohno, Masuo

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Impairments in remote memory stabilization precede hippocampal synaptic and cognitive failures in 5XFAD Alzheimer mouse model von Kimura, Ryoichi, Ohno, Masuo

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Accelerated long‐term forgetting is a BACE1 inhibitor‐reversible incipient cognitive phenotype in Alzheimer’s disease model mice von Ohno, Masuo

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Mitochondrial dysfunction and accumulation of the β-secretase-cleaved C-terminal fragment of APP in Alzheimer's disease transgenic mice von Devi, Latha, Ohno, Masuo

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Phospho-eIF2α level is important for determining abilities of BACE1 reduction to rescue cholinergic neurodegeneration and memory defects in 5XFAD mice von Devi, Latha, Ohno, Masuo

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Deletion of the eIF2α Kinase GCN2 fails to rescue the memory decline associated with Alzheimer's disease von Devi, Latha, Ohno, Masuo

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The polyphenol oleuropein aglycone protects TgCRND8 mice against Aß plaque pathology von Grossi, Cristina, Rigacci, Stefania, Ambrosini, Stefano, Ed Dami, Teresa, Luccarini, Ilaria, Traini, Chiara, Failli, Paola, Berti, Andrea, Casamenti, Fiorella, Stefani, Massimo

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Partial reduction of BACE1 improves synaptic plasticity, recent and remote memories in Alzheimer's disease transgenic mice von Kimura, Ryoichi, Devi, Latha, Ohno, Masuo

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Post-injury treatment with 7,8-dihydroxyflavone, a TrkB receptor agonist, protects against experimental traumatic brain injury via PI3K/Akt signaling von Wu, Chun-Hu, Hung, Tai-Ho, Chen, Chien-Cheng, Ke, Chia-Hua, Lee, Chun-Yen, Wang, Pei-Yi, Chen, Szu-Fu

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Tau reduction diminishes spatial learning and memory deficits after mild repetitive traumatic brain injury in mice von Cheng, Jason S, Craft, Ryan, Yu, Gui-Qiu, Ho, Kaitlyn, Wang, Xin, Mohan, Geetha, Mangnitsky, Sergey, Ponnusamy, Ravikumar, Mucke, Lennart

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Mechanisms underlying insulin deficiency-induced acceleration of β-amyloidosis in a mouse model of Alzheimer's disease von Devi, Latha, Alldred, Melissa J, Ginsberg, Stephen D, Ohno, Masuo

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Inhibition of Polo-like kinase 2 ameliorates pathogenesis in Alzheimer's disease model mice von Lee, Ji Soo, Lee, Yeunkum, André, Emily A, Lee, Kea Joo, Nguyen, Thien, Feng, Yang, Jia, Nuo, Harris, Brent T, Burns, Mark P, Pak, Daniel T S

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Pharmacological activation of the nuclear receptor REV-ERB reverses cognitive deficits and reduces amyloid-β burden in a mouse model of Alzheimer's disease von Roby, Deborah A, Ruiz, Fernanda, Kermath, Bailey A, Voorhees, Jaymie R, Niehoff, Michael, Zhang, Jinsong, Morley, John E, Musiek, Erik S, Farr, Susan A, Burris, Thomas P

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A combination Alzheimer's therapy targeting BACE1 and neprilysin in 5XFAD transgenic mice von Devi, Latha, Ohno, Masuo

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Reversal of autophagy dysfunction in the TgCRND8 mouse model of Alzheimer's disease ameliorates amyloid pathologies and memory deficits von YANG, Dun-Sheng, STAVRIDES, Philip, PAWLIK, Monika, PETERHOFF, Corrinne M, YANG, Austin J, WILSON, Donald A, GEORGE-HYSLOP, Peter St, WESTAWAY, David, MATHEWS, Paul M, LEVY, Efrat, CUERVO, Ana M, NIXON, Ralph A, MOHAN, Panaiyur S, KAUSHIK, Susmita, KUMAR, Asok, OHNO, Masuo, SCHMIDT, Stephen D, WESSON, Daniel, BANDYOPADHYAY, Urmi, YING JIANG

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Alzheimer’s therapy targeting the β-secretase enzyme BACE1: Benefits and potential limitations from the perspective of animal model studies von Ohno, Masuo

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Perinatal Choline Supplementation Reduces Amyloidosis and Increases Choline Acetyltransferase Expression in the Hippocampus of the APPswePS1dE9 Alzheimer's Disease Model Mice von Mellott, Tiffany J, Huleatt, Olivia M, Shade, Bethany N, Pender, Sarah M, Liu, Yi B, Slack, Barbara E, Blusztajn, Jan K

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No Overt Deficits in Aged Tau-Deficient C57Bl/6.Mapttm1(EGFP)Kit GFP Knockin Mice von van Hummel, Annika, Bi, Mian, Ippati, Stefania, van der Hoven, Julia, Volkerling, Alexander, Lee, Wei S, Tan, Daniel C S, Bongers, Andre, Ittner, Arne, Ke, Yazi D, Ittner, Lars M

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APP is cleaved by Bace1 in pre-synaptic vesicles and establishes a pre-synaptic interactome, via its intracellular domain, with molecular complexes that regulate pre-synaptic vesic... von Del Prete, Dolores, Lombino, Franco, Liu, Xinran, D'Adamio, Luciano

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BACE1-cleavage of Sez6 and Sez6L is elevated in Niemann-Pick type C disease mouse brains von Causevic, Mirsada, Dominko, Kristina, Malnar, Martina, Vidatic, Lea, Cermak, Stjepko, Pigoni, Martina, Kuhn, Peer-Hendrik, Colombo, Alessio, Havas, Daniel, Flunkert, Stefanie, McDonald, Jessica, Gunnersen, Jenny M, Hutter-Paier, Birgit, Tahirovic, Sabina, Windisch, Manfred, Krainc, Dimitri, Lichtenthaler, Stefan F, Hecimovic, Silva

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